David A Shafritz

Genes and Pathways Promoting Long-Term Liver Repopulation by hYAP-ERT2 Transduced Hepatocytes and Treatment of Jaundice in Gunn Rats.

Authors:

Esther A Peterson Zsuzsanna Polgar Gnanapackiam S Devakanmalai Yanfeng Li Fadi L Jaber Wei Zhang Xia Wang Niloy J Iqbal John W Murray Namita Roy-Chowdhury Wilber Quispe-Tintaya Alexander Y Maslov Tatyana L Tchaikovskaya Yogeshwar Sharma Leslie E Rogler Sanjeev Gupta Liang Zhu Jayanta Roy-Chowdhury David A Shafritz

Hepatol Commun 2019 Jan 20;3(1):129-146. Epub 2018 Nov 20.

Department of Medicine Marion Bessin Liver Research Center, Albert Einstein College of Medicine Bronx NY.

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January 2019

Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location.

Authors:

Mladen Yovchev Fadi L Jaber Zhonglei Lu Shachi Patel Joseph Locker Leslie E Rogler John W Murray Marius Sudol Mariana D Dabeva Liang Zhu David A Shafritz

Sci Rep 2016 Jan 14;6:19275. Epub 2016 Jan 14.

Marion Bessin Liver Research Center, Division of Gastroenterology and Liver Diseases, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461.

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January 2016

Repopulation of the fibrotic/cirrhotic rat liver by transplanted hepatic stem/progenitor cells and mature hepatocytes.

Authors:

Mladen I Yovchev Yuhua Xue David A Shafritz Joseph Locker Michael Oertel

Hepatology 2014 Jan 18;59(1):284-95. Epub 2013 Nov 18.

Marion Bessin Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, New York, NY; Department of Medicine (Division of Gastroenterology and Liver Diseases), Albert Einstein College of Medicine of Yeshiva University, New York, NY.

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January 2014

Activin A, p15INK4b signaling, and cell competition promote stem/progenitor cell repopulation of livers in aging rats.

Authors:

Anuradha Menthena Christoph I Koehler Jaswinderpal S Sandhu Mladen I Yovchev Ethel Hurston David A Shafritz Michael Oertel

Gastroenterology 2011 Mar 11;140(3):1009-20. Epub 2010 Dec 11.

Marion Bessin Liver Research Center, Division of Gastroenterology and Liver Diseases, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA.

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March 2011

To TWEAK, or not to TWEAK: that is the question.

Authors:

David A Shafritz

Hepatology 2010 Jul;52(1):13-5

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July 2010

Model systems and experimental conditions that lead to effective repopulation of the liver by transplanted cells.

Authors:

David A Shafritz Michael Oertel

Int J Biochem Cell Biol 2011 Feb 18;43(2):198-213. Epub 2010 Jan 18.

Marion Bessin Liver Research Center, Department of Medicine and Division of Hepatology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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February 2011

Purification of fetal liver stem/progenitor cells containing all the repopulation potential for normal adult rat liver.

Authors:

Michael Oertel Anuradha Menthena Yuan-Qing Chen Børge Teisner Charlotte Harken Jensen David A Shafritz

Gastroenterology 2008 Mar 10;134(3):823-32. Epub 2008 Jan 10.

Marion Bessin Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, USA.

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March 2008

Stem cells, cell transplantation and liver repopulation.

Authors:

Michael Oertel David A Shafritz

Biochim Biophys Acta 2008 Feb 23;1782(2):61-74. Epub 2007 Dec 23.

Marion Bessin Liver Research Center, Division of Hepatology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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February 2008

A human hepatocyte factory.

Authors:

David A Shafritz

Nat Biotechnol 2007 Aug;25(8):871-2

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August 2007

Comparison of hepatic properties and transplantation of Thy-1(+) and Thy-1(-) cells isolated from embryonic day 14 rat fetal liver.

Authors:

Michael Oertel Anuradha Menthena Yuan-Qing Chen David A Shafritz

Hepatology 2007 Oct;46(4):1236-45

Marion Bessin Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA.

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October 2007

Inactivation of p27Kip1 promotes chemical mouse liver tumorigenesis in the resistant strain C57BL/6J.

Authors:

Daqian Sun Hao Ren Michael Oertel Rani S Sellers David A Shafritz Liang Zhu

Mol Carcinog 2008 Jan;47(1):47-55

Department of Developmental and Molecular Biology, Marion Bessin Liver Research Center and Albert Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, New York, USA.

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January 2008

New cell surface markers for murine fetal hepatic stem cells identified through high density complementary DNA microarrays.

Authors:

Dirk Nierhoff Lauretta Levoci Sigrid Schulte Tobias Goeser Leslie E Rogler David A Shafritz

Hepatology 2007 Aug;46(2):535-47

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA.

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August 2007

BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm.

Authors:

Valerie Gouon-Evans Lise Boussemart Paul Gadue Dirk Nierhoff Christoph I Koehler Atsushi Kubo David A Shafritz Gordon Keller

Nat Biotechnol 2006 Nov 5;24(11):1402-11. Epub 2006 Nov 5.

Department of Gene and Cell Medicine, Black Family Stem Cell Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, New York 10029, USA.

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November 2006

Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice.

Authors:

Charles S Landis Kosho Yamanouchi Hongchao Zhou Sankar Mohan Namita Roy-Chowdhury David A Shafritz Alan Koretsky Jayanta Roy-Chowdhury Hoby P Hetherington Chandan Guha

Hepatology 2006 Nov;44(5):1250-8

Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.

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November 2006

Properties of cryopreserved fetal liver stem/progenitor cells that exhibit long-term repopulation of the normal rat liver.

Authors:

Michael Oertel Anuradha Menthena Yuan-Qing Chen David A Shafritz

Stem Cells 2006 Oct 15;24(10):2244-51. Epub 2006 Jun 15.

Marion Bessin Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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October 2006

Cell competition leads to a high level of normal liver reconstitution by transplanted fetal liver stem/progenitor cells.

Authors:

Michael Oertel Anuradha Menthena Mariana D Dabeva David A Shafritz

Gastroenterology 2006 Feb;130(2):507-20; quiz 590

Marion Bessin Liver Research Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA.

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February 2006

Liver stem cells and prospects for liver reconstitution by transplanted cells.

Authors:

David A Shafritz Michael Oertel Anuradha Menthena Dirk Nierhoff Mariana D Dabeva

Hepatology 2006 Feb;43(2 Suppl 1):S89-98

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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February 2006

Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation.

Authors:

Wenjun Ju Atsushi Ogawa Joerg Heyer Dirk Nierhof Liping Yu Raju Kucherlapati David A Shafritz Erwin P Böttinger

Mol Cell Biol 2006 Jan;26(2):654-67

Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Pl., Box 1118, New York, New York 10029, USA.

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January 2006

Whole fetal liver transplantation--a new approach to cell therapy.

Authors:

Ran Oren Yigal Breitman Eyal Gur Alexandra Traister Isabel Zvibel Eli Brazovsky David A Shafritz Zamir Halpern

Liver Transpl 2005 Aug;11(8):929-33

Liver Unit, Department of Gastroenterology, Tel Aviv Sourasky Medical Center (TASMC), Tel Aviv, Israel.

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August 2005

Purification and characterization of mouse fetal liver epithelial cells with high in vivo repopulation capacity.

Authors:

Dirk Nierhoff Atsushi Ogawa Michael Oertel Yuan-Qing Chen David A Shafritz

Hepatology 2005 Jul;42(1):130-9

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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July 2005

Bone marrow progenitors are not the source of expanding oval cells in injured liver.

Authors:

Anuradha Menthena Niloyjyoti Deb Michael Oertel Petar N Grozdanov Jaswinder Sandhu Shalin Shah Chandan Guha David A Shafritz Mariana D Dabeva

Stem Cells 2004 ;22(6):1049-61

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.

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April 2005

Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays.

Authors:

Petko M Petkov Jiri Zavadil David Goetz Tearina Chu Robert Carver Charles E Rogler Erwin P Bottinger David A Shafritz Mariana D Dabeva

Hepatology 2004 Mar;39(3):617-27

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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March 2004

p27Kip1 inactivation provides a proliferative advantage to transplanted hepatocytes in DPPIV/Rag2 double knockout mice after repeated host liver injury.

Authors:

Ray-Hwang Yuan Atsushi Ogawa Emi Ogawa David Neufeld Liang Zhu David A Shafritz

Cell Transplant 2003 ;12(8):907-19

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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September 2004

Hepatic stem cells and liver repopulation.

Authors:

Mariana D Dabeva David A Shafritz

Semin Liver Dis 2003 Nov;23(4):349-62

Department of Medicine, Albert Einstein College of Medicine, Marion Bessin Liver Research Center, Bronx, New York 10461, USA.

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November 2003

HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver.

Authors:

Orit Kollet Shoham Shivtiel Yuan-Qing Chen Jenny Suriawinata Swan N Thung Mariana D Dabeva Joy Kahn Asaf Spiegel Ayelet Dar Sarit Samira Polina Goichberg Alexander Kalinkovich Fernando Arenzana-Seisdedos Arnon Nagler Izhar Hardan Michel Revel David A Shafritz Tsvee Lapidot

J Clin Invest 2003 Jul;112(2):160-9

Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.

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July 2003

Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors.

Authors:

Michael Oertel Richard Rosencrantz Yuan-Qing Chen Prashanthi N Thota Jaswinderpal S Sandhu Mariana D Dabeva Annmarie L Pacchia Martin E Adelson Joseph P Dougherty David A Shafritz

Hepatology 2003 May;37(5):994-1005

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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May 2003

Liver stem cells and model systems for liver repopulation.

Authors:

David A Shafritz Mariana D Dabeva

J Hepatol 2002 Apr;36(4):552-64

Marion Bessin Liver Research Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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April 2002

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