David A Okar

David A Okar

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David A Okar

David A Okar

Publications by authors named "David A Okar"

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Molecular coordination of hepatic glucose metabolism by the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase:glucokinase complex.

Mol Endocrinol 2007 Jun 20;21(6):1478-87. Epub 2007 Mar 20.

Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, Minnesota 55417, USA.

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http://dx.doi.org/10.1210/me.2006-0356DOI Listing
June 2007

Enhancing hepatic glycolysis reduces obesity: differential effects on lipogenesis depend on site of glycolytic modulation.

Cell Metab 2005 Aug;2(2):131-40

Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1016/j.cmet.2005.07.003DOI Listing
August 2005

Identification and characterization of the ATP-binding site in human pancreatic glucokinase.

Arch Biochem Biophys 2005 Apr;436(1):23-31

Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.abb.2005.01.018DOI Listing
April 2005

Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Adv Enzyme Regul 2004 ;44:123-54

Veterans Administration Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA.

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http://dx.doi.org/10.1016/j.advenzreg.2003.11.006DOI Listing
March 2005

Reduction of hepatic glucose production as a therapeutic target in the treatment of diabetes.

Curr Drug Targets Immune Endocr Metabol Disord 2005 Mar;5(1):51-9

Department of Biochemistry, Molecular Biology and Biophysics, Medical School, University of Minnesota, 6-155 Jackson Hall, 321 Church Street SE, Minneapolis, Minnesota 55455, USA.

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March 2005

A potential role for fructose-2,6-bisphosphate in the stimulation of hepatic glucokinase gene expression.

Endocrinology 2004 Feb 14;145(2):650-8. Epub 2003 Nov 14.

Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, 321 Church Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1210/en.2003-1290DOI Listing
February 2004

Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice using in vivo (13)C NMR measurements of hepatic carbohydrate metabolism.

Eur J Biochem 2002 Sep;269(18):4418-26

Departments of RadiologyBiochemistry, Molecular Biology and Biophysics Neuroscience University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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September 2002

Starvation amidst plenty: PDKs and diabetes mellitus.

Authors:
David A Okar

Trends Endocrinol Metab 2002 May-Jun;13(4):142

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August 2002

Starvation amidst plenty: PDKs and diabetes mellitus.

Authors:
David A Okar

Trends Biochem Sci 2002 May;27(5):227-8

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May 2002

Increasing fructose 2,6-bisphosphate overcomes hepatic insulin resistance of type 2 diabetes.

Am J Physiol Endocrinol Metab 2002 Jan;282(1):E38-45

Department of Biochemistry, Molecular Biology and Biophysics, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1152/ajpendo.2002.282.1.E38DOI Listing
January 2002