David A Isenberg

David A Isenberg

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Under crossfire: thromboembolic risk in systemic lupus erythematosus.

Rheumatology (Oxford) 2019 Jun;58(6):940-952

Haemostasis Research Unit, Department of Haematology, University College London, London, UK.

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http://dx.doi.org/10.1093/rheumatology/key307DOI Listing
June 2019

Osteopontin and Disease Activity in Patients with Recent-onset Systemic Lupus Erythematosus: Results from the SLICC Inception Cohort.

J Rheumatol 2019 May 15;46(5):492-500. Epub 2019 Jan 15.

From the Rheumatology/Division of Neuro and Inflammation Sciences, Department of Clinical and Experimental Medicine, Linköping University, Linköping; Department of Medicine, Unit of Rheumatology, Karolinska Institutet and Karolinska University Hospital, Stockholm; Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund; Unit for Clinical Therapy Research (ClinTRID), Karolinska University, Stockholm, Sweden; Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, Ontario; Division of Rheumatology, Centre Hospitalier Universitaire (CHU) de Québec - Université Laval, Quebec City, Quebec; Division of Rheumatology, Cumming School of Medicine - University of Calgary, Calgary, Alberta; Division of Rheumatology, Department of Medicine, McGill University Health Centre, Montreal, Quebec; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia; Department of Medicine and Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, Mexico; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea; Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham; Centre for Rheumatology Research, University College, London; Lupus Research Unit, The Rayne Institute, St. Thomas' Hospital, King's College London School of Medicine, London; Lanarkshire Centre for Rheumatology, Hairmyres Hospital, East Kilbride, Scotland; Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, The University of Manchester and UK National Institute for Health Research (NIHR) Manchester Biomedical Research Centre, Manchester University Foundation Trust, Manchester, UK; Cedars-Sinai/David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma; Department of Medicine, State University of New York (SUNY) Downstate Medical Center, Brooklyn, New York; Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama; Department of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Feinstein Institute for Medical Research, Manhasset, New York; Division of Rheumatology and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina; Autoimmunity Institute, Allegheny Health Network, Pittsburgh, Pennsylvania; Northwestern University and Feinberg School of Medicine, Chicago, Illinois; Division of Rheumatology, Emory University School of Medicine, Atlanta, Georgia; University of California San Diego School of Medicine, La Jolla, California; Division of Rheumatology, Medical University of South Carolina, Charleston, South Carolina; Division of Rheumatology, Columbia University Medical Center, New York, New York, USA; Department of Rheumatology, Center for Rheumatology Research Fossvogur Landspitali University Hospital, Reyjkavik, Iceland; Autoimmune Disease Unit, Department of Internal Medicine, Hospital Universitario Cruces, BioCruces Health Research Institute, University of the Basque Country, Barakaldo; Josep Font Autoimmune Diseases Laboratory, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain; Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey; Copenhagen Lupus and Vasculitis Clinic, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Rheumatology, Kantousspital, Schaffhausen, Switzerland.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.180713
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http://dx.doi.org/10.3899/jrheum.180713DOI Listing
May 2019

Construction of a frailty index as a novel health measure in systemic lupus erythematosus.

J Rheumatol 2019 Apr 15. Epub 2019 Apr 15.

Department of Medicine, Division of Rheumatology, Dalhousie University, Halifax, Nova Scotia, Canada; Department of Community Health & Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada; Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada; Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea;Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Instituto Nacional de Ciencias Medicas y Nutrición, Mexico City, Mexico; Cedars-Sinai/David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Divisions of Rheumatology and Clinical Epidemiology, Department of Medicine, McGill University, Montreal, Quebec, Canada; Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA; Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA; Division of Rheumatology, CHU de Québec et Université Laval, Quebec City, Canada; Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, ON, Canada; Arthritis Research UK Epidemiology Unit, Faculty of Biology Medicine and Health, Manchester Academic Health Sciences Center, The University of Manchester, and NIHR Manchester Musculoskeletal Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Center Manchester, UK; Center for Rheumatology, Department of Medicine, University College London, UK; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Lupus Research Unit, The Rayne Institute, St Thomas' Hospital, King's College London School of Medicine, UK, London, UK; Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA; Northwestern University and Feinberg School of Medicine, Chicago, IL, USA; Lupus Center of Excellence, Allegheny Health Network, Pittsburgh, PA, USA; Lanarkshire Center for Rheumatology, Hairmyres Hospital, East Kilbride, Scotland UK; Feinstein Institute for Medical Research, Manhasset, NY, USA; Autoimmune Diseases Research Unit, Department of Internal Medicine, BioCruces Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, Barakaldo, Spain; Emory University School of Medicine, Division of Rheumatology, Atlanta, Georgia, USA Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey; Unit for clinical therapy research (ClinTRID), Karolinska Institute, Stockholm, Sweden; Department of Clinical Sciences Lund, Rheumatology, Lund University, Lund, Sweden. Josep Font Autoimmune Diseases Laboratory, IDIBAPS, Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Spain; Medical University of South Carolina, Charleston, South Carolina, USA; UCSD School of Medicine, La Jolla, CA, USA; Copenhagen Lupus and Vasculitis Clinic, 4242, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; University of Manitoba, Winnipeg, Manitoba, Canada; Hospital for Joint Diseases, NYU, Seligman Center for Advanced Therapeutics, New York NY; Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Center and Dalhousie University, Halifax, Nova Scotia, Canada. Funding for this work was provided by the Nova Scotia Health Authority Research Fund. Dr. Sang-Cheol Bae's work was supported in part by NRF-2017M3A9B4050335, Republic of Korea. Dr. Caroline Gordon's work was supported by Lupus UK and the NIHR /Wellcome Trust Clinical Research Facility. The Montreal General Hospital Lupus Clinic is partially supported by the Singer Family Fund for Lupus Research. Dr. Clarke holds The Arthritis Society Chair in Rheumatic Diseases at the University of Calgary. Dr. Paul R. Fortin presently holds a tier 1 Canada Research Chair on Systemic Autoimmune Rheumatic Diseases at Université Laval, and part of this work was done while he was still holding a Distinguished Senior Investigator of The Arthritis Society. Dr. Bruce is a National Institute for Health Research (NIHR) Senior Investigator and is supported by Arthritis Research UK, the NIHR Manchester Biomedical Centre and the NIHR/Wellcome Trust Manchester Clinical Research Facility. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health. Dr Isenberg and Dr Rahman are supported by and supported by the National Institute for Health, Research University College London Hospitals Biomedical Research Center. The Hopkins Lupus Cohort is supported by the NIH (grant AR43727 and 69572). Dr. Mary Anne Dooley's work was supported by the NIH (grant RR00046). Dr. Ramsey-Goldman's work was supported by the NIH (grants 5UL1TR001422-02, formerly 8UL1TR000150 and UL-1RR-025741, K24-AR-02318, and P60AR064464 formerly P60-AR- 48098). Dr. Ruiz-Irastorza is supported by the Department of Education, Universities and Research of the Basque Government. Dr. Soren Jacobsen is supported by the Danish Rheumatism Association (A3865) and the Novo Nordisk Foundation (A05990). Dr. John G. Hanly is supported by the Canadian Institutes of Health Research (grant MOP-88526). Address Correspondence to: Dr. John G Hanly, Division of Rheumatology, Nova Scotia Rehabilitation Centre (2nd Floor), 1341 Summer Street, Halifax, Nova Scotia, Canada, B3H 4K4.Email:

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http://dx.doi.org/10.3899/jrheum.181338DOI Listing
April 2019

Present and novel biologic drugs in primary Sjögren's syndrome.

Clin Exp Rheumatol 2019 Apr 26. Epub 2019 Apr 26.

Centre for Rheumatology, Department of Medicine, University College London, UK.

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April 2019

Assessment of Response to B-Cell Depletion Using Rituximab in Cutaneous Lupus Erythematosus.

JAMA Dermatol 2018 Dec;154(12):1432-1440

Department of Rheumatology, University College London Hospital, University College London, London, United Kingdom.

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http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamadermatol.2018.3793DOI Listing
December 2018

Impact of pre-transplant time on dialysis on survival in patients with lupus nephritis.

Clin Rheumatol 2018 Sep 11;37(9):2399-2404. Epub 2018 May 11.

Centre for Rheumatology, Division of Medicine, University College London, 250 Euston Road, London, NW1 2PG, UK.

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http://dx.doi.org/10.1007/s10067-018-4115-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097102PMC
September 2018

Gene expression profiling identifies distinct molecular signatures in thrombotic and obstetric antiphospholipid syndrome.

J Autoimmun 2018 Sep 19;93:114-123. Epub 2018 Jul 19.

Centre for Rheumatology Research, Division of Medicine, University College London, Department of Medicine, Rayne Institute, 5 University Street, London, UK, WC1E 6JF, UK.

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http://dx.doi.org/10.1016/j.jaut.2018.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123515PMC
September 2018

Recent developments in biologic therapies for the treatment of patients with systemic lupus erythematosus.

Rheumatology (Oxford) 2018 Apr 5. Epub 2018 Apr 5.

Department of Rheumatology, University College London, London, UK.

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http://dx.doi.org/10.1093/rheumatology/key064DOI Listing
April 2018

Very delayed lupus nephritis: a report of three cases and literature review.

Lupus Sci Med 2018 12;5(1):e000241. Epub 2018 Jan 12.

Centre for Rheumatology, University College London, London, UK.

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http://dx.doi.org/10.1136/lupus-2017-000241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786908PMC
January 2018

TRIM21 and the Function of Antibodies inside Cells.

Trends Immunol 2017 12 11;38(12):916-926. Epub 2017 Aug 11.

Centre for Rheumatology, Division of Medicine, University College London, London, UK.

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http://dx.doi.org/10.1016/j.it.2017.07.005DOI Listing
December 2017

Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity.

Clin Rev Allergy Immunol 2017 Oct;53(2):237-264

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.

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http://dx.doi.org/10.1007/s12016-017-8609-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597704PMC
October 2017

Obinutuzumab induces superior B-cell cytotoxicity to rituximab in rheumatoid arthritis and systemic lupus erythematosus patient samples.

Rheumatology (Oxford) 2017 07;56(7):1227-1237

Centre for Rheumatology, University College London, London, UK2Roche Pharmaceutical Research & Early Development, Roche Innovation Center Zurich, Schlieren, Switzerland3Academic Unit of Cancer Sciences, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1093/rheumatology/kex067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808665PMC
July 2017

Pragmatic Treatment of Patients With Systemic Lupus Erythematosus With Rituximab: Long-Term Effects on Serum Immunoglobulins.

Arthritis Care Res (Hoboken) 2017 06 24;69(6):857-866. Epub 2017 Apr 24.

University College London, Rayne Institute, London, UK.

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http://dx.doi.org/10.1002/acr.22993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485064PMC
June 2017

Mixed connective tissue disease-enigma variations?

Rheumatology (Oxford) 2017 03;56(3):326-333

Centre for Rheumatology, Division of Medicine, University College London, London, UK.

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http://dx.doi.org/10.1093/rheumatology/kew265DOI Listing
March 2017

Belimumab in systemic lupus erythematosus (SLE): evidence-to-date and clinical usefulness.

Ther Adv Musculoskelet Dis 2017 Mar 1;9(3):75-85. Epub 2017 Mar 1.

Centre for Rheumatology, University College London, Room 424, 4th Floor Rayne Building, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1177/1759720X17690474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349337PMC
March 2017

Comment on: Musculoskeletal complication of haematological disease: Reply.

Rheumatology (Oxford) 2017 02 11;56(2):321. Epub 2016 Nov 11.

Internal Medicine Department, ULSM - Hospital Pedro Hispano, Matosinhos, Portugal.

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http://dx.doi.org/10.1093/rheumatology/kew373DOI Listing
February 2017

Rituximab in the treatment of inflammatory myopathies: a review.

Rheumatology (Oxford) 2017 01 27;56(1):26-36. Epub 2016 Apr 27.

Centre for Rheumatology, Department of Medicine, University College London, London, UK

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http://rheumatology.oxfordjournals.org/content/early/2016/04
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http://dx.doi.org/10.1093/rheumatology/kew146DOI Listing
January 2017

Why do patients with myositis die? A retrospective analysis of a single-centre cohort.

Clin Exp Rheumatol 2016 Sep-Oct;34(5):820-826. Epub 2016 Aug 2.

Centre for Rheumatology, Department of Medicine, University College London, UK.

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January 2017

Cross-talk between iNKT cells and monocytes triggers an atheroprotective immune response in SLE patients with asymptomatic plaque.

Sci Immunol 2016 Dec;1(6)

Centre for Rheumatology Research, Department of Medicine, University College London, Rayne Building, London W1CE 6JF, U.K.

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http://dx.doi.org/10.1126/sciimmunol.aah4081DOI Listing
December 2016

Why, why, why de-lupus (does so badly in clinical trials).

Expert Rev Clin Immunol 2016 19;12(2):95-8. Epub 2016 Jan 19.

b Clinical Pharmacology Research Program , Oklahoma Medical Research Foundation , Oklahoma City , OK , USA.

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http://dx.doi.org/10.1586/1744666X.2016.1112270DOI Listing
November 2016

The diagnosis and management of the haematologic manifestations of lupus.

J Autoimmun 2016 11 25;74:139-160. Epub 2016 Jul 25.

Department of Rheumatology, University College London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.07.001DOI Listing
November 2016

Exploring BAFF: its expression, receptors and contribution to the immunopathogenesis of Sjögren's syndrome.

Rheumatology (Oxford) 2016 09 20;55(9):1548-55. Epub 2016 Jan 20.

Centre for Rheumatology Research, Department of Medicine, University College London, London, UK

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http://dx.doi.org/10.1093/rheumatology/kev420DOI Listing
September 2016

DNA-damaging autoantibodies and cancer: the lupus butterfly theory.

Nat Rev Rheumatol 2016 07 24;12(7):429-34. Epub 2016 Mar 24.

Department of Therapeutic Radiology, Yale School of Medicine, 15 York Street, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1038/nrrheum.2016.23DOI Listing
July 2016

What can we learn from systemic lupus erythematosus pathophysiology to improve current therapy?

Expert Rev Clin Immunol 2015 ;11(10):1093-107

b 2 Centre for Rheumatology, University College London Hospitals, London, UK.

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http://dx.doi.org/10.1586/1744666X.2015.1078237DOI Listing
June 2016

Musculoskeletal complications of haematological disease.

Rheumatology (Oxford) 2016 Jun 5;55(6):968-81. Epub 2015 Oct 5.

Centre for Rheumatology, University College London Hospitals, London, UK

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http://www.rheumatology.oxfordjournals.org/lookup/doi/10.109
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http://dx.doi.org/10.1093/rheumatology/kev360DOI Listing
June 2016

Current pharmacological treatment of idiopathic inflammatory myopathies.

Expert Rev Clin Pharmacol 2016 Apr 6;9(4):547-558. Epub 2016 Feb 6.

c Centre for Rheumatology, Department of Medicine , University College London , London , UK.

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http://dx.doi.org/10.1586/17512433.2016.1136561DOI Listing
April 2016

A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus.

Immunity 2016 Mar 8;44(3):683-697. Epub 2016 Mar 8.

Centre for Rheumatology, Division of Medicine, University College London, 5 University Street, London WC1E 6JF, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803914PMC
March 2016

Advances in the treatment of ocular dryness associated with Sjögren׳s syndrome.

Semin Arthritis Rheum 2015 Dec 18;45(3):321-7. Epub 2015 Jun 18.

Department of Rheumatology, University College London Hospital, 3rd Floor Central, 250 Euston Rd, London NW1 2PG, UK.

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http://dx.doi.org/10.1016/j.semarthrit.2015.06.007DOI Listing
December 2015

Examining the prevalence of non-criteria anti-phospholipid antibodies in patients with anti-phospholipid syndrome: a systematic review.

Rheumatology (Oxford) 2015 Nov 7;54(11):2042-50. Epub 2015 Jul 7.

Centre for Rheumatology Research, Division of Medicine, Department of Medicine, Rayne Institute, 5 University Street and

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http://rheumatology.oxfordjournals.org/content/54/11/2042.fu
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http://www.rheumatology.oxfordjournals.org/lookup/doi/10.109
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http://dx.doi.org/10.1093/rheumatology/kev226DOI Listing
November 2015

Belimumab in systemic lupus erythematosus.

RMD Open 2015 3;1(1):e000011. Epub 2015 Mar 3.

Centre for Rheumatology, University College London Hospitals , London , UK.

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http://dx.doi.org/10.1136/rmdopen-2014-000011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612697PMC
October 2015

B-cell survival factors in autoimmune rheumatic disorders.

Ther Adv Musculoskelet Dis 2015 Aug;7(4):122-51

Centre for Rheumatology, University College London, Room 424, 4th Floor Rayne Building, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1177/1759720X15586782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530383PMC
August 2015

Safety and efficacy of hCDR1 (Edratide) in patients with active systemic lupus erythematosus: results of phase II study.

Lupus Sci Med 2015 11;2(1):e000104. Epub 2015 Aug 11.

UCLA & Cedars-Sinai Medical Center , Los Angeles, California , USA.

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http://dx.doi.org/10.1136/lupus-2015-000104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538379PMC
August 2015

Clinical trials perception in rheumatology patients: experience from a single rheumatology tertiary center.

J Rheumatol 2015 Jun 1;42(6):988-93. Epub 2015 Apr 1.

From the Department of Rheumatology, University College London Hospitals National Health Service (NHS) Foundation Trust; Centre for Nephrology, University College London, London, UK.C. Ciurtin, PhD, Consultant Rheumatologist; M. Leandro, PhD, Consultant Rheumatologist; H. Fitz-Clarence, PhD, Consultant Rheumatologist; H. Nguyen, MSc, Rheumatology Researcher; D.A. Isenberg, MD, Academic Director, Centre for Rheumatology Research, Department of Rheumatology, University College London Hospitals NHS Foundation Trust; S.B. Walsh, PhD, Senior Lecturer in Experimental Medicine and Honorary Consultant Nephrologist, Centre for Nephrology, University College London.

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http://dx.doi.org/10.3899/jrheum.141091DOI Listing
June 2015

Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis.

Rheumatology (Oxford) 2015 Apr 30;54(4):722-7. Epub 2014 Sep 30.

Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and Arthritis Research UK Centre for Adolescent Rheumatology, University College London Hospital and Great Ormond Street Hospital, London, UK.

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http://dx.doi.org/10.1093/rheumatology/keu360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372675PMC
April 2015

Asymmetric appearance of immunological abnormalities in close relatives of patients with systemic lupus erythematosus.

Clin Immunol 2015 Apr 28;157(2):226-7. Epub 2015 Jan 28.

Centre for Rheumatology, University College London, London, UK.

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http://dx.doi.org/10.1016/j.clim.2015.01.009DOI Listing
April 2015

Pathology of systemic lupus erythematosus: the challenges ahead.

Methods Mol Biol 2014 ;1134:1-16

Internal Medicine Department, Hospital Garcia de Orta, EPE, Almada, Portugal.

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http://dx.doi.org/10.1007/978-1-4939-0326-9_1DOI Listing
September 2014

A comparison of the outcome of adolescent and adult-onset systemic lupus erythematosus.

Rheumatology (Oxford) 2014 Jun 6;53(6):1130-5. Epub 2014 Feb 6.

Department of Medicine, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal, Department of Rheumatology, University College Hospital, Arthritis Research UK Centre for Adolescent Rheumatology, University College London and Department of Rheumatology, University College Hospital, London, UK.

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http://dx.doi.org/10.1093/rheumatology/ket488DOI Listing
June 2014

Is the age of eponymous diseases in rheumatology over?

Br J Hosp Med (Lond) 2014 Apr;75(4):184-5

Professor of Rheumatology Centre for Rheumatology UCL Division of Medicine University College London, London WC1E 6JF.

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April 2014

Rituximab as an effective alternative therapy in refractory idiopathic inflammatory myopathies.

Clin Exp Rheumatol 2013 Nov-Dec;31(6):896-903. Epub 2013 Sep 18.

Autoimmune Diseases Unit, Department of Internal Medicine, Juan Ramón Jiménez Hospital, Huelva, Andalucía, Spain.

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March 2014

Recent developments in the treatment of patients with systemic lupus erythematosus: focusing on biologic therapies.

Expert Opin Biol Ther 2014 Mar 6;14(3):311-26. Epub 2014 Jan 6.

University College Hospital, Department of Rheumatology , 3rd floor central, 250 Euston Road, London, NW1 2PG , UK.

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http://www.tandfonline.com/doi/full/10.1517/14712598.2014.87
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http://dx.doi.org/10.1517/14712598.2014.871256DOI Listing
March 2014

The coming of age of adolescent rheumatology.

Nat Rev Rheumatol 2014 03 7;10(3):187-93. Epub 2014 Jan 7.

Arthritis Research UK Centre for Adolescent Rheumatology, University College London, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1038/nrrheum.2013.202DOI Listing
March 2014

Systemic lupus erythematosus in 2013. Taking a closer look at biologic therapy for SLE.

Nat Rev Rheumatol 2014 Feb 17;10(2):71-2. Epub 2013 Dec 17.

Centre for Rheumatology, University College London, Room 424, 4th Floor Rayne Building, 5 University Street, London WC1E 6JF, UK.

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http://www.nature.com/articles/nrrheum.2013.203
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http://dx.doi.org/10.1038/nrrheum.2013.203DOI Listing
February 2014

Antinuclear antibodies seroconversion in 100 patients with lupus.

Clin Exp Rheumatol 2013 Jul-Aug;31(4):656. Epub 2013 Apr 9.

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October 2013

Reprint of: B cell elimination in systemic lupus erythematosus. Clin. Immunol. 146(2) 90-103.

Clin Immunol 2013 Sep 4;148(3):344-58. Epub 2013 Apr 4.

Department of Internal Medicine, Egas Moniz Hospital, Lisbon, Portugal.

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http://dx.doi.org/10.1016/j.clim.2013.04.001DOI Listing
September 2013

Aberrant B-lymphocyte responses in lupus: inherent or induced and potential therapeutic targets.

Eur J Clin Invest 2013 Aug 23;43(8):866-80. Epub 2013 May 23.

Bone & Joint Research Unit, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1111/eci.12111DOI Listing
August 2013

B-lymphocyte signalling abnormalities and lupus immunopathology.

Int Rev Immunol 2013 Aug 14;32(4):428-44. Epub 2013 Jun 14.

Bone & Joint Research Unit, William Harvey Research Institute, Barts.

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http://dx.doi.org/10.3109/08830185.2013.788648DOI Listing
August 2013

Assessment of disease activity, damage and quality of life in systemic lupus erythematosus: new aspects.

Best Pract Res Clin Rheumatol 2013 Jun 5;27(3):309-18. Epub 2013 Oct 5.

University College Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.berh.2013.10.003DOI Listing
June 2013

Global trends, potential mechanisms and early detection of organ damage in SLE.

Nat Rev Rheumatol 2013 May 11;9(5):301-10. Epub 2012 Dec 11.

Division of Rheumatology, Department of Medicine, University Medicine Cluster, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Level 10, NUHS Tower Block, Singapore 119228.

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http://dx.doi.org/10.1038/nrrheum.2012.208DOI Listing
May 2013

Dr. Eisenberg replies.

Authors:
David A Isenberg

J Rheumatol 2013 May;40(5):734

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May 2013

Outcome predictors in patients with idiopathic inflammatory myopathies.

Clin Exp Rheumatol 2012 Nov-Dec;30(6):980. Epub 2012 Dec 17.

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March 2013

B cell elimination in systemic lupus erythematosus.

Clin Immunol 2013 Feb 27;146(2):90-103. Epub 2012 Nov 27.

Department of Internal Medicine, Egas Moniz Hospital, Lisbon, Portugal.

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http://dx.doi.org/10.1016/j.clim.2012.11.006DOI Listing
February 2013

CD19+CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation.

Sci Transl Med 2013 Feb;5(173):173ra23

Centre for Rheumatology, Division of Medicine, University College London, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1126/scitranslmed.3005407DOI Listing
February 2013

Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome.

Thromb Haemost 2013 Jan 15;109(1):72-8. Epub 2012 Nov 15.

Centre for Rheumatology, Division of Medicine University College London, Rayne Institute, 4 th Floor, Room 422, 5 University Street, London.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH12-05-0346
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http://dx.doi.org/10.1160/TH12-05-0346DOI Listing
January 2013

Rhubarb and reliability -- a Jane Austen view of systemic lupus erythematosus.

Authors:
David A Isenberg

J Rheumatol 2013 Jan;40(1):7-8

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http://dx.doi.org/10.3899/jrheum.121224DOI Listing
January 2013

Connective tissue diseases: SLE-associated arthropathy: truly a benign entity?

Nat Rev Rheumatol 2012 Dec 13;8(12):695-6. Epub 2012 Nov 13.

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http://dx.doi.org/10.1038/nrrheum.2012.200DOI Listing
December 2012

Rituximab-it was the best of times, it was the worst of times.

Authors:
David A Isenberg

Autoimmun Rev 2012 Sep 12;11(11):790-1. Epub 2012 Feb 12.

University College London, United Kingdom.

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http://dx.doi.org/10.1016/j.autrev.2012.02.005DOI Listing
September 2012

B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels.

Rheumatology (Oxford) 2012 Jul 15;51(7):1208-15. Epub 2012 Feb 15.

Centre for Rheumatology, University College London, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1093/rheumatology/ker526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380246PMC
July 2012

Lipid-antigen presentation by CD1d(+) B cells is essential for the maintenance of invariant natural killer T cells.

Immunity 2012 Mar 8;36(3):477-90. Epub 2012 Mar 8.

Centre for Rheumatology Research, Division of Medicine, University College London, London WC1E 6JF, UK.

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http://dx.doi.org/10.1016/j.immuni.2012.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391684PMC
March 2012

Meryl Streep and the problems of clinical trials.

Authors:
David A Isenberg

Arthritis Res Ther 2012 Mar 23;14(2):113. Epub 2012 Mar 23.

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http://dx.doi.org/10.1186/ar3751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446407PMC
March 2012