Publications by authors named "David A Harrison"

97Publications

Trends in Intensive Care for Patients with COVID-19 in England, Wales and Northern Ireland.

Am J Respir Crit Care Med 2020 Dec 11. Epub 2020 Dec 11.

Intensive Care National Audit and Research Centre, 14207, London, United Kingdom of Great Britain and Northern Ireland;

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December 2020

Anxiety, depression and post-traumatic stress disorder management after critical illness: a UK multi-centre prospective cohort study.

Crit Care 2020 11 2;24(1):633. Epub 2020 Nov 2.

Critical Care Research Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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November 2020

COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland.

Intensive Care Med 2020 11 9;46(11):2035-2047. Epub 2020 Oct 9.

Intensive Care National Audit and Research Centre (ICNARC), Napier House, 24 High Holborn, London, WC1V 6AZ, UK.

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November 2020

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people.

Heart 2020 10 31;106(19):1503-1511. Epub 2020 Jul 31.

Division of Cardiovascular Medicine, British Heart Foundation Centre of Research Excellence, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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October 2020

Does delaying discharge from intensive care until after tracheostomy removal affect 30-day mortality? Propensity score matched cohort study.

BMJ Open 2020 06 7;10(6):e037762. Epub 2020 Jun 7.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, Oxon, UK.

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June 2020

A framework for extending trial design to facilitate missing data sensitivity analyses.

BMC Med Res Methodol 2020 03 17;20(1):66. Epub 2020 Mar 17.

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.

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March 2020

Higher ICU Capacity Strain Is Associated With Increased Acute Mortality in Closed ICUs.

Crit Care Med 2020 May;48(5):709-716

Intensive Care National Audit & Research Centre, London, United Kingdom.

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May 2020

Improving the Face Validity of a Composite Endpoint.

Crit Care Med 2020 02;48(2):257-258

Clinical Trials Unit, Intensive Care National Audit & Research Centre (ICNARC), London, United Kingdom.

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February 2020

Interventions to reduce Staphylococcus aureus in the management of eczema.

Cochrane Database Syst Rev 2019 10 29;2019(10). Epub 2019 Oct 29.

University of Nottingham, Centre of Evidence Based Dermatology, Queen's Medical Centre, Derby Road, Nottingham, UK, NG7 2UH.

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October 2019

Risk Factors at Index Hospitalization Associated With Longer-term Mortality in Adult Sepsis Survivors.

JAMA Netw Open 2019 05 3;2(5):e194900. Epub 2019 May 3.

Intensive Care National Audit & Research Centre, London, United Kingdom.

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May 2019

ICU Structure and Outcomes Following Traumatic Brain Injury.

Crit Care Med 2019 01;47(1):e68-e69

Division of Anaesthesia, University of Cambridge, Cambridge, United Kingdom Intensive Care National Audit & Research Centre, London, United Kingdom.

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January 2019

Anxiety, Depression and Post Traumatic Stress Disorder after critical illness: a UK-wide prospective cohort study.

Crit Care 2018 11 23;22(1):310. Epub 2018 Nov 23.

Associate Professor of Intensive Care Medicine, Oxford University Hospitals NHS Trust, Oxford, UK.

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November 2018

Relationship between height and outcomes among critically ill adults: a cohort study.

Intensive Care Med 2018 Dec 12;44(12):2122-2133. Epub 2018 Nov 12.

Department of Critical Care Medicine, Sunnybrook Hospital, 2075 Bayview Ave., Room D1.08, Toronto, ON, M4N 3M5, Canada.

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December 2018

A Comparison of Mortality From Sepsis in Brazil and England: The Impact of Heterogeneity in General and Sepsis-Specific Patient Characteristics.

Crit Care Med 2019 01;47(1):76-84

Department of Critical Care and Graduate Program in Translational Medicine, D'Or Institute for Research and Education - IDOR, Rio De Janeiro, Brazil.

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January 2019

'Lumping or splitting' in paediatric acute respiratory distress syndrome (PARDS).

Intensive Care Med 2018 09 24;44(9):1548-1550. Epub 2018 Aug 24.

Respiratory Critical Care and Anaesthesia Unit, UCL Great Ormond Street Institute of Child Health, London, UK.

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September 2018

Seeing their side versus feeling their pain: Differential consequences of perspective-taking and empathy at work.

J Appl Psychol 2018 Aug 16;103(8):894-915. Epub 2018 Apr 16.

Management Department, McCombs School of Business, University of Texas at Austin.

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August 2018

Estimating attributable fraction of mortality from sepsis to inform clinical trials.

J Crit Care 2018 06 31;45:33-39. Epub 2018 Jan 31.

Interdepartmental Division of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, D5 03, Toronto, Ontario M4N 3M5, Canada. Electronic address:

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June 2018

Incidence and Outcomes for Patients With Cirrhosis Admitted to the United Kingdom Critical Care Units.

Crit Care Med 2018 05;46(5):705-712

Liver Intensive Therapy Unit, Institute of Liver Studies, King's College Hospital, Denmark Hill, London, United Kingdom.

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May 2018

Exploring the impact of using measured or estimated values for height and weight on the relationship between BMI and acute hospital mortality.

J Crit Care 2018 04 15;44:196-202. Epub 2017 Nov 15.

Department of Intensive Care, St. George's University Hospitals NHS Foundation Trust, London SW17 0QT, United Kingdom.

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April 2018

Religious/Spiritual Struggle in Young Adult Hematopoietic Cell Transplant Survivors.

J Adolesc Young Adult Oncol 2018 04 3;7(2):210-216. Epub 2017 Nov 3.

7 Division of Pediatric Oncology, Department of Pediatrics, Mary Bridge Hospital/MultiCare Health System , Tacoma, Washington.

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April 2018

The effect of postal questionnaire burden on response rate and answer patterns following admission to intensive care: a randomised controlled trial.

BMC Med Res Methodol 2017 03 27;17(1):49. Epub 2017 Mar 27.

Kadoorie Centre for Critical Care Research and Education, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK.

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March 2017

Association of Intensive Care Unit Patient-to-Intensivist Ratios With Hospital Mortality.

JAMA Intern Med 2017 03;177(3):388-396

Interdepartmental Division of Critical Care Medicine, University of Toronto, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada6Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, New York7Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.

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March 2017

qSOFA for Identifying Sepsis Among Patients With Infection.

JAMA 2017 01;317(3):267-268

Intensive Care National Audit & Research Centre (ICNARC), London, United Kingdom.

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January 2017

Psychometric assessment of the Family Satisfaction in the Intensive Care Unit questionnaire in the United Kingdom.

J Crit Care 2017 04 5;38:346-350. Epub 2016 Nov 5.

Clinical Trials Unit, Intensive Care National Audit and Research Centre, London, United Kingdom.

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April 2017

Development and validation of the new ICNARC model for prediction of acute hospital mortality in adult critical care.

J Crit Care 2017 04 21;38:335-339. Epub 2016 Nov 21.

Intensive Care National Audit & Research Centre (ICNARC), London, UK. Electronic address:

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April 2017

Determining best methods to screen for religious/spiritual distress.

Support Care Cancer 2017 02 6;25(2):471-479. Epub 2016 Oct 6.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.

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February 2017

Maternal morbidity and mortality from severe sepsis: a national cohort study.

BMJ Open 2016 08 23;6(8):e012323. Epub 2016 Aug 23.

National Perinatal Epidemiology Unit (NPEU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.

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August 2016

Differences in Impact of Definitional Elements on Mortality Precludes International Comparisons of Sepsis Epidemiology-A Cohort Study Illustrating the Need for Standardized Reporting.

Crit Care Med 2016 Dec;44(12):2223-2230

1Department of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.2Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom.3Intensive Care National Audit and Research Centre, London, United Kingdom.

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December 2016

Relationship Between Peak Lactate and Patient Outcome Following High-Risk Gastrointestinal Surgery: Influence of the Nature of Their Surgery: Elective Versus Emergency.

Crit Care Med 2016 May;44(5):918-25

1Surrey Peri-operative Anaesthesia Critical care collaborative Research group (SPACeR), Faculty of Health and Medical Sciences, University of Surrey, Surrey, United Kingdom. 2Intensive Care Unit, Royal Surrey County Hospital, Guildford, United Kingdom. 3National Intensive Care Surveillance, Quality Secretariat Building, Castle Street Hospital for Women, Colombo, Sri Lanka. 4Intensive Care National Audit and Research Centre (ICNARC), London, United Kingdom.

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May 2016

Cost-effectiveness of a cardiac output-guided haemodynamic therapy algorithm in high-risk patients undergoing major gastrointestinal surgery.

Perioper Med (Lond) 2015 14;4:13. Epub 2015 Dec 14.

Queen Mary University of London, London, EC1M 6BQ UK ; Adult Critical Care Unit, Royal London Hospital, Whitechapel, London, E1 1BB UK.

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December 2015

Ups and downs of the expatriate experience? Understanding work adjustment trajectories and career outcomes.

J Appl Psychol 2016 Apr 14;101(4):549-68. Epub 2015 Dec 14.

Department of Management, Opus College of Business, University of St. Thomas.

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April 2016

Spiritual or religious struggle in hematopoietic cell transplant survivors.

Psychooncology 2017 02 15;26(2):270-277. Epub 2015 Nov 15.

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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February 2017

Regional variation in critical care provision and outcome after high-risk surgery.

Intensive Care Med 2015 Oct 23;41(10):1809-16. Epub 2015 Jul 23.

Intensive Care National Audit and Research Centre, London, UK.

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October 2015

Factors that influence the way local communities respond to consultation processes about major service change: A qualitative study.

Health Policy 2015 Sep 1;119(9):1210-7. Epub 2015 May 1.

Department of Applied Health Research, University College London, 1-19 Torrington Place, London WC1E 7HB, UK.

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September 2015

Who gets credit for input? Demographic and structural status cues in voice recognition.

J Appl Psychol 2015 Nov 27;100(6):1765-84. Epub 2015 Apr 27.

Department of Management and Organizations.

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November 2015

External Validation and Recalibration of Risk Prediction Models for Acute Traumatic Brain Injury among Critically Ill Adult Patients in the United Kingdom.

J Neurotrauma 2015 Oct 12;32(19):1522-37. Epub 2015 Jun 12.

1 Clinical Trials Unit, Intensive Care National Audit and Research Centre , Napier House, London, United Kingdom .

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October 2015

Factors that influence the way communities respond to proposals for major changes to local emergency services: a qualitative study.

PLoS One 2015 25;10(3):e0120766. Epub 2015 Mar 25.

Department of Applied Health Research, University College London, 1-19 Torrington Place, London WC1E 6BT, United Kingdom.

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March 2016

Trial of early, goal-directed resuscitation for septic shock.

N Engl J Med 2015 Apr 17;372(14):1301-11. Epub 2015 Mar 17.

From the Clinical Trials Unit, Intensive Care National Audit and Research Centre (P.R.M., G.S.P., D.A.H., R.J., S.E.H., K.M.R.), Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine (M.Z.S., R.D.G.), and Faculty of Medicine, Imperial College London (D.B.), Department of Acute Medicine, Chelsea and Westminster Hospital NHS Foundation Trust (D.B.), and Bloomsbury Institute of Intensive Care Medicine, University College London (M.S.), London, the Department of Intensive Care Medicine, University of Birmingham, Birmingham (J.F.B.), Department of Cardiovascular Sciences, University of Leicester, Leicester (T.J.C.), and Nuffield Division of Anaesthetics, University of Oxford, Oxford (J.D.Y.) - all in the United Kingdom; and the Departments of Surgery and Emergency Medicine, Washington University at St. Louis, St. Louis (T.M.O.).

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April 2015

External validation of the Intensive Care National Audit & Research Centre (ICNARC) risk prediction model in critical care units in Scotland.

BMC Anesthesiol 2014 15;14:116. Epub 2014 Dec 15.

Intensive Care National Audit & Research Centre (ICNARC), Napier House, 24 High Holborn, London, WC1V 6AZ UK.

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July 2015

The impact of the organization of high-dependency care on acute hospital mortality and patient flow for critically ill patients.

Am J Respir Crit Care Med 2015 Jan;191(2):186-93

1 Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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January 2015

The CALORIES trial: statistical analysis plan.

Crit Care Resusc 2014 Dec;16(4):248-54

Intensive Care National Audit and Research Centre, London, United Kingdom.

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December 2014

Trial of the route of early nutritional support in critically ill adults.

N Engl J Med 2014 Oct 1;371(18):1673-84. Epub 2014 Oct 1.

From the Clinical Trials Unit, Intensive Care National Audit and Research Centre (S.E.H., F.P., D.A.H., K.M.R.), the Departments of Nutrition and Dietetics (D.E.B.) and Adult Critical Care (D.E.B., R.B.), Guy's and St. Thomas' NHS Foundation Trust, the Department of Intensive Care, Imperial College Healthcare NHS Trust (E.S., R.L.), the Division of Asthma, Allergy and Lung Biology, King's College London (R.B.), National Institute for Health Research Biomedical Research Centre, University College London Hospitals NHS Foundation Trust and University College London (G.B., M.G.M.), and the Department of Surgery and Cancer, Imperial College London (R.L.) - all in London.

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October 2014

Why try to predict ICU outcomes?

Curr Opin Crit Care 2014 Oct;20(5):544-9

Intensive Care National Audit & Research Centre (ICNARC), London, United Kingdom.

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October 2014

Development and validation of risk models to predict outcomes following in-hospital cardiac arrest attended by a hospital-based resuscitation team.

Resuscitation 2014 Aug 14;85(8):993-1000. Epub 2014 May 14.

Intensive Care National Audit & Research Centre (ICNARC), Napier House, 24 High Holborn, London WC1V 6AZ, UK.

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August 2014

Incidence and outcome of in-hospital cardiac arrest in the United Kingdom National Cardiac Arrest Audit.

Resuscitation 2014 Aug 15;85(8):987-92. Epub 2014 Apr 15.

Intensive Care National Audit & Research Centre (ICNARC), Napier House High Holborn, London WC1V 6AZ, UK.

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August 2014

The Protocolised Management in Sepsis (ProMISe) trial statistical analysis plan.

Crit Care Resusc 2013 Dec;15(4):311-7

Clinical Trials Unit, Intensive Care National Audit and Research Centre, London, United Kingdom.

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December 2013

The presentation, recognition and management of bipolar depression in primary care.

J Gen Intern Med 2013 Dec;28(12):1648-56

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 1959 NE Pacific St, Box 356560, Seattle, WA, 98195-6560, USA,

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December 2013

Relation between volume and outcome for patients with severe sepsis in United Kingdom: retrospective cohort study.

BMJ 2012 May 29;344:e3394. Epub 2012 May 29.

Department of Critical Care, Respiratory Division, McGill University, 1650 Cedar Avenue, Montreal, Quebec, Canada H3G 1A4.

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May 2012

Prevalence and outcome of cirrhosis patients admitted to UK intensive care: a comparison against dialysis-dependent chronic renal failure patients.

Intensive Care Med 2012 Jun 29;38(6):991-1000. Epub 2012 Mar 29.

Department of Clinical Pharmacology, University College London, 5 University Street, London WC1E 6JF, UK.

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June 2012

Is Drotrecogin alfa (activated) for adults with severe sepsis, cost-effective in routine clinical practice?

Crit Care 2011 26;15(5):R228. Epub 2011 Sep 26.

Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, 15-17 Tavistock Place, London, WC1H 9SH, UK.

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August 2012

Centrality and charisma: comparing how leader networks and attributions affect team performance.

J Appl Psychol 2011 Nov 5;96(6):1209-22. Epub 2011 Sep 5.

School of Management, University at Buffalo, Buffalo, NY 14260, USA.

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November 2011

Comparison of medical admissions to intensive care units in the United States and United Kingdom.

Am J Respir Crit Care Med 2011 Jun 25;183(12):1666-73. Epub 2011 Mar 25.

Department of Anesthesiology, Columbia University, New York, New York, USA.

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June 2011

Debunking four myths about employee silence.

Harv Bus Rev 2010 Jun;88(6):26

Cornell's Johnson School, USA.

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June 2010

The effects of critical care outreach services before and after critical care: a matched-cohort analysis.

J Crit Care 2010 Jun;25(2):196-204

Intensive Care National Audit & Research Centre, Tavistock House, Tavistock Square, London WC1H 9HR, UK.

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June 2010

Bad apples, bad cases, and bad barrels: meta-analytic evidence about sources of unethical decisions at work.

J Appl Psychol 2010 Jan;95(1):1-31

Department of Management and Organization, Pennsylvania State University, University Park, PA16801, USA.

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January 2010