David A Fox

David A Fox

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David A Fox

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CD13/Aminopeptidase N Is a Potential Therapeutic Target for Inflammatory Disorders.

J Immunol 2020 Jan;204(1):3-11

Division of Rheumatology, Clinical Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI 48109; and

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http://dx.doi.org/10.4049/jimmunol.1900868DOI Listing
January 2020

Pharmacological inhibition of TAK1, with the selective inhibitor takinib, alleviates clinical manifestation of arthritis in CIA mice.

Arthritis Res Ther 2019 Dec 17;21(1):292. Epub 2019 Dec 17.

Department of Pharmacology and Cancer Biology, Duke University School of Medicine, LSRC C112, 308 Research Drive, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1186/s13075-019-2073-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918687PMC
December 2019

Patterns of glucocorticoid prescribing and provider-level variation in a commercially insured incident rheumatoid arthritis population: A retrospective cohort study.

Semin Arthritis Rheum 2019 Sep 7. Epub 2019 Sep 7.

VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA; Institute for Healthcare Policy and Innovation, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/j.semarthrit.2019.09.002DOI Listing
September 2019

Angiogenic and Arthritogenic Properties of the Soluble Form of CD13.

J Immunol 2019 Jul 12;203(2):360-369. Epub 2019 Jun 12.

Division of Rheumatology, Clinical Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI 48109.

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http://dx.doi.org/10.4049/jimmunol.1801276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644048PMC
July 2019

Absence of complement component 3 does not prevent classical pathway-mediated hemolysis.

Blood Adv 2019 Jun;3(12):1808-1814

Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1182/bloodadvances.2019031591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595256PMC
June 2019

Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.

Proc Natl Acad Sci U S A 2019 02 12;116(9):3695-3702. Epub 2019 Feb 12.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109;

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http://dx.doi.org/10.1073/pnas.1813006116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397533PMC
February 2019

The role of CD6 in autoimmune diseases.

Authors:
David A Fox

Cell Mol Immunol 2018 11 23;15(11):1001-1002. Epub 2018 Mar 23.

Division of Rheumatology and Clinical Autoimmunity Center of Excellence, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/s41423-018-0015-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207704PMC
November 2018

Targeting CD6 for the treatment of experimental autoimmune uveitis.

J Autoimmun 2018 06 19;90:84-93. Epub 2018 Feb 19.

Department of Immunology, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2018.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949263PMC
June 2018

Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.

J Immunol 2018 06 25;200(12):4094-4101. Epub 2018 Apr 25.

Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195;

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http://dx.doi.org/10.4049/jimmunol.1701716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988965PMC
June 2018

Clinical and experimental evidence for targeting CD6 in immune-based disorders.

Autoimmun Rev 2018 May 9;17(5):493-503. Epub 2018 Mar 9.

Group of Immunereceptors of the Innate and Adaptive System, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Servei d'Immunologia, Hospital Clínic de Barcelona, Barcelona, Spain; Departament de Biomedicina, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972183005
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http://dx.doi.org/10.1016/j.autrev.2017.12.004DOI Listing
May 2018

Establishing clinical severity for PROMIS measures in adult patients with rheumatic diseases.

Qual Life Res 2018 Mar 5;27(3):755-764. Epub 2017 Oct 5.

Division of Rheumatology, University of Michigan, 300 North Ingalls Building, Room 7C27, Ann Arbor, MI, 48109-5422, USA.

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http://dx.doi.org/10.1007/s11136-017-1709-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845827PMC
March 2018

Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Sci Immunol 2018 03;3(21)

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/sciimmunol.aar3701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497166PMC
March 2018

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

Arthritis Res Ther 2018 02 12;20(1):31. Epub 2018 Feb 12.

Division of Rheumatology and Clinical Autoimmunity Center of Excellence, Department of Internal Medicine, University of Michigan Medical School, 4368 BSRB, 109 Zina Pitcher Drive, Ann Arbor, MI, 48109-2200, USA.

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http://dx.doi.org/10.1186/s13075-018-1519-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809993PMC
February 2018

CD318 is a ligand for CD6.

Proc Natl Acad Sci U S A 2017 08 31;114(33):E6912-E6921. Epub 2017 Jul 31.

Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1704008114
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http://dx.doi.org/10.1073/pnas.1704008114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565428PMC
August 2017

Transforming growth factor β activated kinase 1: a potential therapeutic target for rheumatic diseases.

Rheumatology (Oxford) 2017 07;56(7):1060-1068

Department of Pharmaceutical Sciences, Washington State University College of Pharmacy, Spokane, WA.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/kew301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850516PMC
July 2017

Seven-Year Outcomes of the Silicone Arthroplasty in Rheumatoid Arthritis Prospective Cohort Study.

Arthritis Care Res (Hoboken) 2017 07 9;69(7):973-981. Epub 2017 Jun 9.

The University of Michigan School of Public Health, Ann Arbor.

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http://dx.doi.org/10.1002/acr.23105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376377PMC
July 2017

Synovial cellular and molecular markers in rheumatoid arthritis.

Semin Immunopathol 2017 06 11;39(4):385-393. Epub 2017 May 11.

Division of Rheumatology and the Clinical Autoimmunity Center of Excellence, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/s00281-017-0631-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521018PMC
June 2017

CD6 as a potential target for treating multiple sclerosis.

Proc Natl Acad Sci U S A 2017 03 16;114(10):2687-2692. Epub 2017 Feb 16.

Department of Immunology, Cleveland Clinic, Cleveland, OH 44195;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1615253114
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http://dx.doi.org/10.1073/pnas.1615253114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347585PMC
March 2017

TLRs, future potential therapeutic targets for RA.

Autoimmun Rev 2017 Feb 15;16(2):103-113. Epub 2016 Dec 15.

Division of Rheumatology, Jesse Brown VA, Medical Center, Chicago, IL 60612, USA; Department of Medicine, Division of Rheumatology, University of Illinois at Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290220PMC
February 2017

Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes.

PLoS One 2016;11(9):e0162008. Epub 2016 Sep 22.

Division of Rheumatology and Clinical Autoimmunity Center of Excellence, Department of Internal Medicine University of Michigan, Ann Arbor, Michigan, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033571PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162008PLOS
September 2016

Phospholipase D enzymes facilitate IL-17- and TNFα-induced expression of proinflammatory genes in rheumatoid arthritis synovial fibroblasts (RASF).

Immunol Lett 2016 06 4;174:9-18. Epub 2016 Apr 4.

The University of Michigan, Ann Arbor, USA. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2016.04.001DOI Listing
June 2016

Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis.

Arthritis Res Ther 2016 Apr 12;18:87. Epub 2016 Apr 12.

Division of Rheumatology, Department of Internal Medicine and Clinical Autoimmunity Center of Excellence, University of Michigan Medical School, 109 Zina Pitcher Drive, 4023 BSRB, Ann Arbor, MI, 48109-2200, USA.

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http://dx.doi.org/10.1186/s13075-016-0984-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830090PMC
April 2016

Activation of the Thromboxane A2 Receptor by 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma.

J Invest Dermatol 2015 Dec 19;135(12):3153-3162. Epub 2015 Aug 19.

Department of Internal Medicine, Division of Rheumatology, University of Michigan Scleroderma Program, Ann Arbor, Michigan, USA; Department of Internal Medicine, Division of Rheumatology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1038/jid.2015.323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648660PMC
December 2015

Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts.

Arthritis Res Ther 2014 ;16(5):411

Department of Internal Medicine, Division of Rheumatology, University of Michigan Medical School, 109 Zina Pitcher Dr., 4388 BSRB, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1186/s13075-014-0411-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558991PMC
August 2015

Citrullination: A Specific Target for the Autoimmune Response in Rheumatoid Arthritis.

Authors:
David A Fox

J Immunol 2015 Jul;195(1):5-7

Division of Rheumatology and Clinical Autoimmunity Center of Excellence, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109

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http://dx.doi.org/10.4049/jimmunol.1501021DOI Listing
July 2015

SH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis model.

PLoS One 2014 21;9(8):e105518. Epub 2014 Aug 21.

Department of Oral and Craniofacial Sciences, School of Dentistry, University of Missouri-Kansas City, Kansas City, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105518PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140794PMC
May 2015

Patient expectations and long-term outcomes in rheumatoid arthritis patients: results from the SARA (Silicone Arthroplasty in Rheumatoid Arthritis) study.

Clin Rheumatol 2015 Apr 30;34(4):641-51. Epub 2014 Sep 30.

Department of Surgery, Section of Plastic Surgery, University of Michigan Health System, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/s10067-014-2775-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374599PMC
April 2015

Killer B lymphocytes and their fas ligand positive exosomes as inducers of immune tolerance.

Front Immunol 2015 20;6:122. Epub 2015 Mar 20.

Department of Internal Medicine-Rheumatology, University of Michigan Medical School , Ann Arbor, MI , USA ; Graduate Training Program in Immunology, University of Michigan Medical School , Ann Arbor, MI , USA.

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http://dx.doi.org/10.3389/fimmu.2015.00122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367442PMC
April 2015

Variation in rheumatoid hand and wrist surgery among medicare beneficiaries: a population-based cohort study.

J Rheumatol 2015 Mar 15;42(3):429-36. Epub 2015 Jan 15.

From the Department of Surgery, Section of Plastic Surgery, Department of Internal Medicine, and Division of Rheumatology, University of Michigan Medical School, University of Michigan Health System, Ann Arbor, Michigan; and the Department of Mathematics, New York City College of Technology, New York, New York, USA.L. Zhong, MD, MPH, Clinical Research Coordinator; K.C. Chung, MD, MS, Professor of Surgery, Assistant Dean for Faculty Affairs, Department of Surgery, Section of Plastic Surgery; O. Baser, PhD, Adjunct Professor, Department of Internal Medicine, University of Michigan Medical School; D.A. Fox, MD, Professor, Department of Internal Medicine, Division Chief, Division of Rheumatology; J.F. Waljee, MD, MS, Assistant Professor, Department of Surgery, Section of Plastic Surgery, University of Michigan Health System; H. Yuce, PhD, Associate Professor, Department of Mathematics, New York City College of Technology.

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http://dx.doi.org/10.3899/jrheum.140658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827611PMC
March 2015

The incidence of upper and lower extremity surgery for rheumatoid arthritis among Medicare beneficiaries.

J Bone Joint Surg Am 2015 Mar;97(5):403-10

Section of Plastic Surgery, Department of Surgery (J.W., L.Z., and K.C.C.), and Department of Internal Medicine (O.B. and D.A.F.), University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5340. E-mail address for K.C. Chung:

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http://jbjs.org/content/jbjsam/97/5/403.full.pdf
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http://jbjs.org/cgi/doi/10.2106/JBJS.N.00802
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http://dx.doi.org/10.2106/JBJS.N.00802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344595PMC
March 2015

Current and future approaches to the treatment of immunologic diseases: new targets and new therapeutic agents.

Authors:
David A Fox

Transl Res 2015 Feb 17;165(2):251-4. Epub 2014 Oct 17.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2014.10.009DOI Listing
February 2015

Noxa in rheumatic diseases: present understanding and future impact.

Rheumatology (Oxford) 2014 Sep 17;53(9):1539-46. Epub 2013 Dec 17.

Department of Pharmacology, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, Toledo, OH and Division of Rheumatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1093/rheumatology/ket408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135581PMC
September 2014

Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.

J Pharmacol Exp Ther 2014 Jun 4;349(3):480-6. Epub 2014 Apr 4.

Department of Pharmacology (A.J.H.) and Department of Internal Medicine, Division of Rheumatology (P.T., M.A.A., J.H.R., P.C., D.A.F., D.K.), University of Michigan Medical Center, Ann Arbor, Michigan; Vahlteich Medicinal Chemistry Core, College of Pharmacy, University of Michigan, Ann Arbor, Michigan (S.D.L.); and Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan (R.R.N.).

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http://dx.doi.org/10.1124/jpet.114.213520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019321PMC
June 2014

Human B Cell-Derived Lymphoblastoid Cell Lines Constitutively Produce Fas Ligand and Secrete MHCII(+)FasL(+) Killer Exosomes.

Front Immunol 2014 2;5:144. Epub 2014 Apr 2.

Graduate Program in Immunology, University of Michigan , Ann Arbor, MI , USA ; Division of Rheumatology, Department of Internal Medicine, University of Michigan , Ann Arbor, MI , USA.

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http://dx.doi.org/10.3389/fimmu.2014.00144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980107PMC
April 2014

T cell subsets and their role in the pathogenesis of rheumatic disease.

Curr Opin Rheumatol 2014 Mar;26(2):204-10

aUniversity of Arkansas, Little Rock, Arkansas bUniversity of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000036DOI Listing
March 2014

Regulation of Th17 maturation by interleukin 4.

Crit Rev Immunol 2013 ;33(5):379-87

Division of Rheumatology, University of Michigan, Ann Arbor, MI 48109-5422.

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http://dx.doi.org/10.1615/critrevimmunol.2013007096DOI Listing
January 2014

Voriconazole-induced periostitis causing arthralgias mimicking a flare of granulomatosis with polyangiitis.

J Clin Rheumatol 2013 Dec;19(8):444-5

From the Division of Rheumatology, Department of Medicine, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1097/RHU.0000000000000045DOI Listing
December 2013

The roles of IFN-γ versus IL-17 in pathogenic effects of human Th17 cells on synovial fibroblasts.

Mod Rheumatol 2013 Nov 11;23(6):1140-50. Epub 2013 Jan 11.

University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/s10165-012-0811-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710715PMC
November 2013

The effect of swan neck and boutonniere deformities on the outcome of silicone metacarpophalangeal joint arthroplasty in rheumatoid arthritis.

Plast Reconstr Surg 2013 Sep;132(3):597-603

Section of Plastic Surgery, University of Michigan Health System, 1500 East Medical Center Drive, 2130 Taubman Center, SPC 5340, Ann Arbor, MI 48109-5340, USA.

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http://dx.doi.org/10.1097/PRS.0b013e31829ad1c1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153347PMC
September 2013

Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling.

Arthritis Rheum 2013 Mar;65(3):618-26

University of Michigan School of Medicine, Ann Arbor, MI 48109-5680, USA.

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http://dx.doi.org/10.1002/art.37814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582785PMC
March 2013

Reflecting on early arthritis.

J Rheumatol 2012 Nov;39(11):2059-61

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http://dx.doi.org/10.3899/jrheum.121030DOI Listing
November 2012

Treg cells to the rescue.

Authors:
David A Fox

Arthritis Rheum 2012 Aug;64(8):2426-8

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http://dx.doi.org/10.1002/art.34511DOI Listing
August 2012

Kinase inhibition--a new approach to the treatment of rheumatoid arthritis.

Authors:
David A Fox

N Engl J Med 2012 Aug;367(6):565-7

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http://dx.doi.org/10.1056/NEJMe1206315DOI Listing
August 2012

Epilogue: how will we care for patients with early arthritis?

Rheum Dis Clin North Am 2012 May 25;38(2):427-9. Epub 2012 May 25.

Division of Rheumatology, Department of Medicine, Keck School of Medicine at the University of Southern California, USC Medical Center, IRD 427, 2010 Zonal Avenue, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/j.rdc.2012.04.003DOI Listing
May 2012

Sensitivity and resistance to regulation by IL-4 during Th17 maturation.

J Immunol 2011 Nov 26;187(9):4440-50. Epub 2011 Sep 26.

Division of Rheumatology, Department of Internal Medicine and Rheumatic Disease Research Core Center, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.4049/jimmunol.1002860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197869PMC
November 2011

Properties of the International Classification for Functioning, Disability and Health in assessing hand outcomes in patients with rheumatoid arthritis.

J Rehabil Med 2011 Mar;43(4):292-8

Department of Surgery, Section of Plastic Surgery, University of Michigan Health System, 1500 E. Medical Center Drive 2130 Taubman Center, Ann Arbor, MI 48109-5340, USA.

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http://dx.doi.org/10.2340/16501977-0671DOI Listing
March 2011

Historical perspective on the etiology of rheumatoid arthritis.

Hand Clin 2011 Feb;27(1):1-10

Section of Plastic Surgery, University of Michigan Health System, 2130 Taubman Center, SPC 5340, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5340, USA.

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http://dx.doi.org/10.1016/j.hcl.2010.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119866PMC
February 2011

Advances in the medical treatment of rheumatoid arthritis.

Hand Clin 2011 Feb;27(1):11-20

Division of Rheumatology, University of Michigan, 3918 Taubman Center, 1500 East Medical Center, SPC 5358, Ann Arbor, MI 48109-5358, USA.

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http://dx.doi.org/10.1016/j.hcl.2010.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135413PMC
February 2011

A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis.

Arthritis Res Ther 2011 Feb 4;13(1):R15. Epub 2011 Feb 4.

Division of Rheumatology and Rheumatic Diseases Research Core Center, Department of Internal Medicine, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

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http://arthritis-research.biomedcentral.com/articles/10.1186
Publisher Site
http://dx.doi.org/10.1186/ar3239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241359PMC
February 2011

Are Th17 cells an appropriate new target in the treatment of rheumatoid arthritis?

Clin Transl Sci 2010 Dec;3(6):319-26

University of Michigan Health System, Department of Internal Medicine, Division of Rheumatology, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2010.00233.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057561PMC
December 2010

Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets.

Best Pract Res Clin Rheumatol 2010 Aug;24(4):463-77

Division of Rheumatology, Department of Internal Medicine and Rheumatic Disease Core Center, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1016/j.berh.2009.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146352PMC
August 2010

Preface: rheumatoid arthritis--halfway there.

Authors:
David A Fox

Rheum Dis Clin North Am 2010 May;36(2):xiii-xiv

Division of Rheumatology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.rdc.2010.03.005DOI Listing
May 2010

Cell-cell interactions in rheumatoid arthritis synovium.

Rheum Dis Clin North Am 2010 May;36(2):311-23

Division of Rheumatology and Rheumatic Diseases Research Core Center, 3918 Taubman Center, 1500 East Medical Center Drive, The University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.rdc.2010.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879397PMC
May 2010

Targeting IL-17 and Th17 cells in rheumatoid arthritis.

Rheum Dis Clin North Am 2010 May;36(2):345-66

Section of Rheumatology, Department of Medicine, The University of Arizona, 1501 North Campbell Avenue, Tucson, AZ 85724, USA.

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http://dx.doi.org/10.1016/j.rdc.2010.02.006DOI Listing
May 2010

Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4.

Arthritis Res Ther 2009 26;11(5):R158. Epub 2009 Oct 26.

Section of Rheumatology, Department of Medicine, University of Arizona, 1501 N. Campbell Avenue, Rm 6310, Tucson, Arizona 85724, USA.

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http://dx.doi.org/10.1186/ar2838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787258PMC
February 2010

Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis.

Arthritis Res Ther 2009 25;11(4):R128. Epub 2009 Aug 25.

Department of Internal Medicine, Division of Rheumatology, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1186/ar2795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745812PMC
December 2009

Outcomes of silicone arthroplasty for rheumatoid metacarpophalangeal joints stratified by fingers.

J Hand Surg Am 2009 Nov;34(9):1647-52

Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI 48109-0340, USA.

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http://dx.doi.org/10.1016/j.jhsa.2009.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413434PMC
November 2009

A multicenter clinical trial in rheumatoid arthritis comparing silicone metacarpophalangeal joint arthroplasty with medical treatment.

J Hand Surg Am 2009 May-Jun;34(5):815-23

Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI 48109-5340, USA.

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http://dx.doi.org/10.1016/j.jhsa.2009.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381953PMC
July 2009

A prospective study comparing outcomes after reconstruction in rheumatoid arthritis patients with severe ulnar drift deformities.

Plast Reconstr Surg 2009 Jun;123(6):1769-77

Department of Surgery, Division of Rheumatology, Section of Plastic Surgery, University of Michigan Health System, Ann Arbor, Mich, USA.

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http://dx.doi.org/10.1097/PRS.0b013e3181a65b5aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735852PMC
June 2009

The future of ILAR.

Authors:
David A Fox

Clin Rheumatol 2009 May 28;28(5):493-4. Epub 2009 Feb 28.

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http://dx.doi.org/10.1007/s10067-009-1136-9DOI Listing
May 2009

Unity in the field of rheumatology: the role of the ACR.

Authors:
David A Fox

Arthritis Rheum 2009 Feb;60(2):313-6

University of Michigan, Ann Arbor, MI 48109-0358, USA.

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http://dx.doi.org/10.1002/art.24334DOI Listing
February 2009

CD19+CD5+ B cells in primary IgA nephropathy.

J Am Soc Nephrol 2008 Nov 23;19(11):2130-9. Epub 2008 Jul 23.

Department of Immunology, Wuhan University School of Medicine, Wuhan University, Dong Hu Road 115, 430071 Wuchang, Wuhan, P.R. China.

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http://dx.doi.org/10.1681/ASN.2007121303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573008PMC
November 2008

Regulatory T cells in rheumatoid arthritis.

Curr Rheumatol Rep 2008 Oct;10(5):405-12

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http://dx.doi.org/10.1007/s11926-008-0065-yDOI Listing
October 2008

Th17 cells in human disease.

Immunol Rev 2008 Jun;223:87-113

Department of Internal Medicine, Division of Rheumatology, Rheumatic Disease Core Center, University of Michigan, Ann Arbor, MI 48109-5358, USA.

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http://doi.wiley.com/10.1111/j.1600-065X.2008.00628.x
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http://dx.doi.org/10.1111/j.1600-065X.2008.00628.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299089PMC
June 2008

High-throughput profiling of ion channel activity in primary human lymphocytes.

Anal Chem 2008 May 24;80(10):3728-35. Epub 2008 Apr 24.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://deepblue.lib.umich.edu/bitstream/2027.42/61560/1/dane
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http://pubs.acs.org/doi/abs/10.1021/ac800164v
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May 2008

Interactions of T cells with fibroblast-like synoviocytes: role of the B7 family costimulatory ligand B7-H3.

J Immunol 2008 Mar;180(5):2989-98

Rheumatic Disease Core Center and Division of Rheumatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109-0358, USA.

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http://dx.doi.org/10.4049/jimmunol.180.5.2989DOI Listing
March 2008

The past and the future of Arthritis & Rheumatism: a view from the American College of Rheumatology.

Authors:
David A Fox

Arthritis Rheum 2008 Feb;58(2 Suppl):S7-S10

Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48109-0358, USA.

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http://dx.doi.org/10.1002/art.23052DOI Listing
February 2008

Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cells.

Am J Pathol 2007 Nov 6;171(5):1588-98. Epub 2007 Sep 6.

Department of Internal Medicine, Division of Rheumatology, Rheumatic Disease Core Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.2353/ajpath.2007.070004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043519PMC
November 2007

Cells of the synovium in rheumatoid arthritis. T lymphocytes.

Arthritis Res Ther 2007 ;9(1):202

Department of Internal Medicine, Division of Rheumatology and Rheumatic Diseases Core Center, University of Michigan Medical School, Ann Arbor, MI 48109-2200, USA.

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http://dx.doi.org/10.1186/ar2107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860060PMC
April 2007

Regulatory T cell defects in rheumatoid arthritis.

Arthritis Rheum 2007 Mar;56(3):710-3

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http://dx.doi.org/10.1002/art.22415DOI Listing
March 2007