Daved H Fremont

Daved H Fremont

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Daved H Fremont

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Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.

Cell 2019 Jun 9;177(7):1725-1737.e16. Epub 2019 May 9.

Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.04.006DOI Listing
June 2019

Molluscum contagiosum virus MC80 sabotages MHC-I antigen presentation by targeting tapasin for ER-associated degradation.

PLoS Pathog 2019 Apr 29;15(4):e1007711. Epub 2019 Apr 29.

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.plos.org/10.1371/journal.ppat.1007711
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http://dx.doi.org/10.1371/journal.ppat.1007711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508746PMC
April 2019

Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice.

Cell Rep 2019 Feb;26(6):1585-1597.e4

Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420780PMC
February 2019

Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.

Proc Natl Acad Sci U S A 2018 09 7;115(39):E9201-E9210. Epub 2018 Sep 7.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110;

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http://dx.doi.org/10.1073/pnas.1805797115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166816PMC
September 2018

Altered compensatory cytokine signaling underlies the discrepancy between and mice.

J Exp Med 2018 05 23;215(5):1417-1435. Epub 2018 Mar 23.

Department of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, MO

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http://dx.doi.org/10.1084/jem.20171784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940266PMC
May 2018

Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in Mice.

J Virol 2018 Apr 14;92(7). Epub 2018 Mar 14.

Department of Medicine/Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, USA

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http://dx.doi.org/10.1128/JVI.00038-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972878PMC
April 2018

Cross-priming induces immunodomination in the presence of viral MHC class I inhibition.

PLoS Pathog 2018 02 14;14(2):e1006883. Epub 2018 Feb 14.

Division of Rheumatology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812664PMC
February 2018

Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor.

Cell 2018 01 21;172(3):534-548.e19. Epub 2017 Dec 21.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.037DOI Listing
January 2018

Targeting of IL-2 to cytotoxic lymphocytes as an improved method of cytokine-driven immunotherapy.

Oncoimmunology 2017 10;6(2):e1265721. Epub 2017 Jan 10.

Department of Surgery, University of Virginia , Charlottesville, VA, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1265721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353927PMC
January 2017

Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy.

Nat Commun 2016 09 21;7:12878. Epub 2016 Sep 21.

Department of Surgery, Washington University in St Louis, 660 South Euclid Avenue, St Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036003PMC
http://dx.doi.org/10.1038/ncomms12878DOI Listing
September 2016

Structural Basis of Zika Virus-Specific Antibody Protection.

Cell 2016 Aug 27;166(4):1016-1027. Epub 2016 Jul 27.

Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA; The Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983199PMC
August 2016

Discovery of a proteinaceous cellular receptor for a norovirus.

Science 2016 08 18;353(6302):933-6. Epub 2016 Aug 18.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1126/science.aaf1220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484048PMC
August 2016

Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.

Structure 2016 Jan 3;24(1):57-69. Epub 2015 Dec 3.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2015.10.018DOI Listing
January 2016

Correlating RANK ligand/RANK binding kinetics with osteoclast formation and function.

J Cell Biochem 2015 Nov;116(11):2476-83

Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1002/jcb.25191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581524PMC
November 2015

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Cell 2015 Nov 6;163(5):1095-1107. Epub 2015 Nov 6.

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.10.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659373PMC
November 2015

Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily.

Viruses 2015 Aug 28;7(9):4878-98. Epub 2015 Aug 28.

Department of Pathology and Immunology, Washington University School of Medicine,  St. Louis, MO 63110, USA.

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http://dx.doi.org/10.3390/v7092848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584292PMC
August 2015

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites.

J Immunol 2015 Jul 10;195(2):587-601. Epub 2015 Jun 10.

Division of Infectious Diseases, Allergy, and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO 63104; Department of Microbiology and Immunology, Edward A. Doisy Research Center, Saint Louis University School of Medicine, Saint Louis, MO 63104

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http://www.jimmunol.org/content/early/2015/06/09/jimmunol.14
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1402545
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http://dx.doi.org/10.4049/jimmunol.1402545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490942PMC
July 2015

Target selection for structural genomics of infectious diseases.

Methods Mol Biol 2014 ;1140:35-51

Dept. of Structural and Molecular Biology, University College London, Gower Street, WC1E 6BT, London, UK.

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http://dx.doi.org/10.1007/978-1-4939-0354-2_3DOI Listing
October 2014

Eukaryotic expression systems for structural studies.

Methods Mol Biol 2014 ;1140:107-16

Center for Structural Genomics of Infectious Diseases, Computational Institute, University of Chicago, Chicago, IL, 60557, USA.

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http://dx.doi.org/10.1007/978-1-4939-0354-2_8DOI Listing
October 2014

Oxidative refolding from inclusion bodies.

Methods Mol Biol 2014 ;1140:145-57

Center for Structural Genomics of Infectious Diseases, Computational Institute, University of Chicago, Chicago, IL, 60557, USA.

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http://dx.doi.org/10.1007/978-1-4939-0354-2_11DOI Listing
October 2014

Manipulation of receptor oligomerization as a strategy to inhibit signaling by TNF superfamily members.

Sci Signal 2014 Aug 19;7(339):ra80. Epub 2014 Aug 19.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Division of Bone and Mineral Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://stke.sciencemag.org/cgi/doi/10.1126/scisignal.2004948
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http://dx.doi.org/10.1126/scisignal.2004948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206197PMC
August 2014

Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement.

PLoS Pathog 2014 Apr 17;10(4):e1004072. Epub 2014 Apr 17.

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990716PMC
April 2014

Structural basis of Flavivirus NS1 assembly and antibody recognition.

Proc Natl Acad Sci U S A 2014 Mar 4;111(11):4285-90. Epub 2014 Mar 4.

Departments of Pathology and Immunology, Medicine, Molecular Microbiology, and Biochemistry and Molecular Biophysics, Washington University in St. Louis, St. Louis, MO 63110.

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http://dx.doi.org/10.1073/pnas.1322036111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964132PMC
March 2014

The unusual dynamics of parasite actin result from isodesmic polymerization.

Nat Commun 2013 ;4:2285

Department of Molecular Microbiology, Washington University School of Medicine, St Louis, Missouri 63110-1093, USA.

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http://dx.doi.org/10.1038/ncomms3285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765016PMC
February 2014

MMTV superantigens coerce an unconventional topology between the TCR and MHC class II.

J Immunol 2014 Feb 22;192(4):1896-906. Epub 2014 Jan 22.

Laboratoire d'Immunologie Moléculaire, Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec HC3 3J7, Canada;

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http://dx.doi.org/10.4049/jimmunol.1203130DOI Listing
February 2014

Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor.

J Virol 2014 Jan 30;88(1):538-46. Epub 2013 Oct 30.

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1128/JVI.02729-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911705PMC
January 2014

The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states.

J Virol 2013 Dec 9;87(24):13729-40. Epub 2013 Oct 9.

Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.02340-13
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http://dx.doi.org/10.1128/JVI.02340-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838241PMC
December 2013

Cowpox virus employs a two-pronged strategy to outflank MHCI antigen presentation.

Mol Immunol 2013 Sep 10;55(2):156-8. Epub 2013 Jan 10.

Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, United States.

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http://dx.doi.org/10.1016/j.molimm.2012.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737064PMC
September 2013

Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope.

PLoS Pathog 2012 4;8(10):e1002930. Epub 2012 Oct 4.

Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464233PMC
April 2013

Structural mechanism of ER retrieval of MHC class I by cowpox.

PLoS Biol 2012 27;10(11):e1001432. Epub 2012 Nov 27.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.plos.org/10.1371/journal.pbio.1001432
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http://dx.doi.org/10.1371/journal.pbio.1001432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507924PMC
April 2013

The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1.

Virology 2013 Apr 28;439(1):57-64. Epub 2013 Feb 28.

Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.

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http://dx.doi.org/10.1016/j.virol.2013.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608513PMC
April 2013

Crystal structure of the cowpox virus-encoded NKG2D ligand OMCP.

J Virol 2013 Jan 31;87(2):840-50. Epub 2012 Oct 31.

Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.

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http://dx.doi.org/10.1128/JVI.01948-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554055PMC
January 2013

Structure of the St. Louis encephalitis virus postfusion envelope trimer.

J Virol 2013 Jan 31;87(2):818-28. Epub 2012 Oct 31.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1128/JVI.01950-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554068PMC
January 2013

RANKL employs distinct binding modes to engage RANK and the osteoprotegerin decoy receptor.

Structure 2012 Nov 2;20(11):1971-82. Epub 2012 Oct 2.

Department of Pathology and Immunology, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1016/j.str.2012.08.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607351PMC
November 2012

Subversion of cytokine networks by virally encoded decoy receptors.

Immunol Rev 2012 Nov;250(1):199-215

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://doi.wiley.com/10.1111/imr.12009
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http://dx.doi.org/10.1111/imr.12009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693748PMC
November 2012

Crystal structure of the Japanese encephalitis virus envelope protein.

J Virol 2012 Feb 7;86(4):2337-46. Epub 2011 Dec 7.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1128/JVI.06072-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302414PMC
February 2012

Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature.

Virology 2012 Jan 12;422(2):174-84. Epub 2011 Nov 12.

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.virol.2011.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356770PMC
January 2012

Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides.

J Biol Chem 2011 Oct 31;286(41):35329-33. Epub 2011 Aug 31.

Dipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, Viale Europa 11, 25123 Brescia, Italy.

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http://dx.doi.org/10.1074/jbc.C111.290494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195614PMC
October 2011

Structural and biophysical analysis of BST-2/tetherin ectodomains reveals an evolutionary conserved design to inhibit virus release.

J Biol Chem 2011 Jan 17;286(4):2987-97. Epub 2010 Nov 17.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M110.190538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024793PMC
January 2011

Genotype-specific neutralization and protection by antibodies against dengue virus type 3.

J Virol 2010 Oct 11;84(20):10630-43. Epub 2010 Aug 11.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Ave., Box 8051, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.01190-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950583PMC
October 2010

Basic and translational applications of engineered MHC class I proteins.

Trends Immunol 2010 Oct 9;31(10):363-9. Epub 2010 Sep 9.

Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.it.2010.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949479PMC
October 2010

Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.

J Virol 2010 Sep 30;84(18):9227-39. Epub 2010 Jun 30.

Department of Medicine,Washington University School of Medicine, 660 South Euclid Ave., Box 8051, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.01087-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937608PMC
September 2010

A short N-terminal peptide motif on flavivirus nonstructural protein NS1 modulates cellular targeting and immune recognition.

J Virol 2010 Sep 30;84(18):9516-32. Epub 2010 Jun 30.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Ave., Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.00775-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937659PMC
September 2010

Cutting edge: FcR-like 5 on innate B cells is targeted by a poxvirus MHC class I-like immunoevasin.

J Immunol 2010 Jul 2;185(1):28-32. Epub 2010 Jun 2.

Division of Pediatric Rheumatology, Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.4049/jimmunol.1000240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321838PMC
July 2010

Preparation of stable single-chain trimers engineered with peptide, beta2 microglobulin, and MHC heavy chain.

Curr Protoc Immunol 2009 Nov;Chapter 17:Unit17.5

Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1002/0471142735.im1705s87DOI Listing
November 2009

Capturing a flavivirus pre-fusion intermediate.

PLoS Pathog 2009 Nov 26;5(11):e1000672. Epub 2009 Nov 26.

Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776511PMC
November 2009

T-cell tolerance for variability in an HLA class I-presented influenza A virus epitope.

J Virol 2009 Sep 24;83(18):9206-14. Epub 2009 Jun 24.

Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA.

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http://dx.doi.org/10.1128/JVI.00932-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738244PMC
September 2009

MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution.

Proc Natl Acad Sci U S A 2009 May 30;106(20):8290-5. Epub 2009 Apr 30.

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0903196106
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http://dx.doi.org/10.1073/pnas.0903196106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688861PMC
May 2009

A therapeutic antibody against west nile virus neutralizes infection by blocking fusion within endosomes.

PLoS Pathog 2009 May 29;5(5):e1000453. Epub 2009 May 29.

Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1371/journal.ppat.1000453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679195PMC
May 2009

The structural immunology of antibody protection against West Nile virus.

Immunol Rev 2008 Oct;225:212-25

Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2008.00676.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646609PMC
October 2008

Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development.

Cell Host Microbe 2008 Sep;4(3):229-38

Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institutes of Health, 33 North Drive, Building 33, Room 1E19A.2, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.chom.2008.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678546PMC
September 2008

Ebola images emerge from the cave.

Cell Host Microbe 2008 Aug;4(2):87-9

Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S193131280800230
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http://dx.doi.org/10.1016/j.chom.2008.07.011DOI Listing
August 2008

MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells.

J Exp Med 2008 May 28;205(5):1201-11. Epub 2008 Apr 28.

Department of Pathology and Immunology, Washington University, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1084/jem.20072579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373850PMC
May 2008

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.

Nat Struct Mol Biol 2008 Mar 10;15(3):312-7. Epub 2008 Feb 10.

Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907-2054, USA.

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http://dx.doi.org/10.1038/nsmb.1382DOI Listing
March 2008

Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator.

J Immunol 2008 Jan;180(2):940-7

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.4049/jimmunol.180.2.940DOI Listing
January 2008

Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.

J Exp Med 2007 Dec 10;204(13):3157-72. Epub 2007 Dec 10.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1084/jem.20071677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150966PMC
December 2007

Induction of epitope-specific neutralizing antibodies against West Nile virus.

J Virol 2007 Nov 22;81(21):11828-39. Epub 2007 Aug 22.

Departments of Medicine, Molecular Microbiology, and Pathology and Immunology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.00643-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168772PMC
November 2007

Structural engineering of pMHC reagents for T cell vaccines and diagnostics.

Chem Biol 2007 Aug;14(8):909-22

Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.chembiol.2007.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601489PMC
August 2007

Antigen-specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis.

Eur J Immunol 2007 Jul;37(7):1845-54

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1002/eji.200737192DOI Listing
July 2007

Patterns of nonclassical MHC antigen presentation.

Nat Immunol 2007 Jun;8(6):563-8

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/ni1475DOI Listing
June 2007

Disulfide bond engineering to trap peptides in the MHC class I binding groove.

J Immunol 2007 May;178(10):6280-9

Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.4049/jimmunol.178.10.6280DOI Listing
May 2007

The chemokine binding protein M3 prevents diabetes induced by multiple low doses of streptozotocin.

J Immunol 2007 Apr;178(7):4623-31

Immunobiology Center, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA.

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http://dx.doi.org/10.4049/jimmunol.178.7.4623DOI Listing
April 2007

The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection.

Cell Host Microbe 2007 Apr;1(2):135-45

Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.chom.2007.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656919PMC
April 2007

Crystal structure of the West Nile virus envelope glycoprotein.

J Virol 2006 Dec 20;80(23):11467-74. Epub 2006 Sep 20.

Department of Pathology & Immunology, Washington University School of Medicine, Campus Box 8118, 660 South Euclid Avenue, St. Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1128/JVI.01125-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1642602PMC
December 2006

Antibody recognition and neutralization determinants on domains I and II of West Nile Virus envelope protein.

J Virol 2006 Dec 11;80(24):12149-59. Epub 2006 Oct 11.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Ave., Box 8051, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.01732-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1676294PMC
December 2006

Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b.

Adv Exp Med Biol 2006 ;581:115-20

Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1007/978-0-387-33012-9_20DOI Listing
December 2006

West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H.

Proc Natl Acad Sci U S A 2006 Dec 28;103(50):19111-6. Epub 2006 Nov 28.

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1073/pnas.0605668103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664712PMC
December 2006

Structural determinants of chemokine binding by an Ectromelia virus-encoded decoy receptor.

J Virol 2006 Aug;80(15):7439-49

Department of Pathology and Immunology, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1128/JVI.00576-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563704PMC
August 2006

West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody.

Proc Natl Acad Sci U S A 2006 Aug 8;103(33):12400-4. Epub 2006 Aug 8.

Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, IN 47907-2054, USA.

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http://dx.doi.org/10.1073/pnas.0603488103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567891PMC
August 2006

Structural definition of the H-2Kd peptide-binding motif.

J Biol Chem 2006 Apr 10;281(15):10618-25. Epub 2006 Feb 10.

Department of Pathology and Immunology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1074/jbc.M510511200DOI Listing
April 2006

Structural definition of the F-actin-binding THATCH domain from HIP1R.

Nat Struct Mol Biol 2006 Feb 15;13(2):121-30. Epub 2006 Jan 15.

Department of Pathology and Immunology, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/nsmb1043DOI Listing
February 2006