Dave Sprengers

Dave Sprengers

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Dave Sprengers

Dave Sprengers

Publications by authors named "Dave Sprengers"

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Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth.

Cells 2020 Jan 4;9(1). Epub 2020 Jan 4.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.3390/cells9010121DOI Listing
January 2020

Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma.

Carcinogenesis 2019 03;40(1):155-163

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Gravendijkwal, NL, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/carcin/bgy130DOI Listing
March 2019

Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma.

J Mol Med (Berl) 2019 01 19;97(1):77-88. Epub 2018 Nov 19.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room Na-617, 's-Gravendijkwal 230, 3015CE, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s00109-018-1717-7
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http://dx.doi.org/10.1007/s00109-018-1717-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326978PMC
January 2019

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas.

Gastroenterology 2017 10 23;153(4):1107-1119.e10. Epub 2017 Jun 23.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Centre, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.06.017DOI Listing
October 2017

Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury.

Gastroenterology 2017 10 14;153(4):1133-1147. Epub 2017 Jul 14.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.07.006DOI Listing
October 2017

Factors associated with ethnical disparity in overall survival for patients with hepatocellular carcinoma.

Oncotarget 2017 Feb;8(9):15193-15204

Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.14771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362478PMC
February 2017

Multiple biopsy passes and the risk of complications of percutaneous liver biopsy.

Eur J Gastroenterol Hepatol 2017 Jan;29(1):36-41

aDepartment of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands bDepartment of Gastroenterology and Hepatology, AZ Nikolaas, Sint-Niklaas, Belgium cToronto Centre for Liver Disease, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://pdfs.journals.lww.com/eurojgh/2017/01000/Multiple_bio
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http://dx.doi.org/10.1097/MEG.0000000000000731DOI Listing
January 2017

Evidence of good prognosis of hepatocellular adenoma in post-menopausal women.

J Hepatol 2016 12 12;65(6):1163-1170. Epub 2016 Aug 12.

The Department of Gastroenterology and Hepatology, Erasmus Medical Centre, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.07.047DOI Listing
December 2016

Distinct Antiviral Potency of Sofosbuvir Against Hepatitis C and E Viruses.

Gastroenterology 2016 12 1;151(6):1251-1253. Epub 2016 Nov 1.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center and Postgraduate School Molecular Medicine, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2016.09.061DOI Listing
December 2016

Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling.

Neoplasia 2016 Dec 13;18(12):711-723. Epub 2016 Nov 13.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2016.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110474PMC
December 2016

IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN-stimulated genes.

FASEB J 2016 10 21;30(10):3352-3367. Epub 2016 Jun 21.

Department of Gastroenterology and Hepatology, Postgraduate School Molecular Medicine, Erasmus MC-University Medical Center, Rotterdam, The Netherlands; and

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http://dx.doi.org/10.1096/fj.201600356RDOI Listing
October 2016

Short article: Management of ruptured hepatocellular carcinoma in a European tertiary care center.

Eur J Gastroenterol Hepatol 2016 Aug;28(8):963-6

Departments of aGastroenterology and Hepatology bRadiology cSurgery, Erasmus MC University Medical Center Rotterdam dDepartment of Surgery, Division of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam eDepartment of Gastroenterology and Hepatology, Máxima Medical Center, Veldhoven, The Netherlands.

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http://dx.doi.org/10.1097/MEG.0000000000000652DOI Listing
August 2016

Hepatocellular carcinoma in noncirrhotic livers is associated with steatosis rather than steatohepatitis: potential implications for pathogenesis.

Eur J Gastroenterol Hepatol 2016 Aug;28(8):955-62

aDepartment of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht bDepartment of Gastroenterology and Hepatology cDepartment of Surgery, Erasmus Medical Center, Rotterdam dDepartment of Medical Oncology eDepartment of Gastroenterology and Hepatology fDepartment of Pathology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/MEG.0000000000000641DOI Listing
August 2016

Hepatocellular carcinoma in cirrhotic versus noncirrhotic livers: results from a large cohort in the Netherlands.

Eur J Gastroenterol Hepatol 2016 Mar;28(3):352-9

aDepartment of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht Departments of bGastroenterology and Hepatology cSurgery, Erasmus Medical Center, Rotterdam dDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden Departments of eMedical Oncology fGastroenterology and Hepatology gPathology, Academic Medical Center Amsterdam hDepartment of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/MEG.0000000000000527DOI Listing
March 2016

Requirement of the eukaryotic translation initiation factor 4F complex in hepatitis E virus replication.

Antiviral Res 2015 Dec 23;124:11-9. Epub 2015 Oct 23.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2015.10.016DOI Listing
December 2015

To target or not to target viral antigens in HBV related HCC?

J Hepatol 2015 Jun 21;62(6):1449-50. Epub 2015 Feb 21.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2015.01.043DOI Listing
June 2015

Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors.

Oncoimmunology 2015 Jun 19;4(6):e1008355. Epub 2015 Mar 19.

Department of Gastroenterology and Hepatology; Erasmus MC University Medical Center ; Rotterdam, the Netherlands ; Department of Gastroenterology and Hepatology; Academic Medical Center; University of Amsterdam ; the Netherlands.

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http://dx.doi.org/10.1080/2162402X.2015.1008355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485712PMC
June 2015

Multipotent mesenchymal stromal cells in liver cancer: implications for tumor biology and therapy.

Biochim Biophys Acta 2014 Dec 6;1846(2):439-45. Epub 2014 Sep 6.

Department of Gastroenterology and Hepatology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0304419X140008
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http://dx.doi.org/10.1016/j.bbcan.2014.08.008DOI Listing
December 2014

Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer.

Hepatology 2013 Jan 4;57(1):183-94. Epub 2012 Dec 4.

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.26013DOI Listing
January 2013

T-cell suppression mediated by regulatory T cells infiltrating hepatic tumors can be overcome by GITRL treatment.

Oncoimmunology 2013 Jan;2(1):e22450

Department of Gastroenterology and Hepatology; Erasmus MC-University Medical Center; Rotterdam, The Netherlands.

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http://dx.doi.org/10.4161/onci.22450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583921PMC
January 2013

Distinct requirements for CD1d intracellular transport for development of V(alpha)14 iNKT cells.

J Immunol 2009 Aug 8;183(3):1780-8. Epub 2009 Jul 8.

Department of Dermatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.4049/jimmunol.0901354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839504PMC
August 2009

Critical role for CD1d-restricted invariant NKT cells in stimulating intrahepatic CD8 T-cell responses to liver antigen.

Gastroenterology 2008 Jun 21;134(7):2132-43. Epub 2008 Feb 21.

Department of Dermatology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.02.037DOI Listing
June 2008

Induction of regulatory T-cells and interleukin-10-producing cells in non-responders to pegylated interferon-alpha therapy for chronic hepatitis B.

Antivir Ther 2007 ;12(7):1087-96

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.

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December 2007

Flowcytometric quantitation of hepatitis B viral antigens in hepatocytes from regular and fine-needle biopsies.

J Virol Methods 2007 Jun 27;142(1-2):189-97. Epub 2007 Feb 27.

Department of Surgery, Erasmus MC-University Medical Center, Rotterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S016609340700053
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http://dx.doi.org/10.1016/j.jviromet.2007.01.027DOI Listing
June 2007

Favorable effect of adefovir on the number and functionality of myeloid dendritic cells of patients with chronic HBV.

Hepatology 2006 Oct;44(4):907-14

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.21340DOI Listing
October 2006

Analysis of intrahepatic HBV-specific cytotoxic T-cells during and after acute HBV infection in humans.

J Hepatol 2006 Aug 6;45(2):182-9. Epub 2006 Feb 6.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2005.12.022DOI Listing
August 2006

Coarse vs. fine needle aspiration biopsy.

J Hepatol 2004 Sep;41(3):503-4; author reply 504

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http://dx.doi.org/10.1016/j.jhep.2004.04.037DOI Listing
September 2004

Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B.

Hepatology 2004 Sep;40(3):738-46

Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.20366DOI Listing
September 2004