Publications by authors named "Daryl Waggott"

40Publications

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.

Sci Rep 2018 04 24;8(1):6451. Epub 2018 Apr 24.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-24735-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915424PMC
April 2018

Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort.

J Pers Med 2017 May 24;7(2). Epub 2017 May 24.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jpm7020003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491979PMC
May 2017

Erratum to: A bedr way of genomic interval processing.

Source Code Biol Med 2017 9;12. Epub 2017 Jan 9.

Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, M5G 0A3 Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13029-016-0061-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223540PMC
January 2017

A bedr way of genomic interval processing.

Source Code Biol Med 2016 15;11:14. Epub 2016 Dec 15.

Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, M5G 0A3 Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13029-016-0059-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157088PMC
December 2016

A genome-wide association study of non-HPV-related head and neck squamous cell carcinoma identifies prognostic genetic sequence variants in the MAP-kinase and hormone pathways.

Cancer Epidemiol 2016 06 9;42:173-80. Epub 2016 May 9.

Ontario Cancer Institute and Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada,; Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canep.2016.05.001DOI Listing
June 2016

Medical implications of technical accuracy in genome sequencing.

Genome Med 2016 Mar 2;8(1):24. Epub 2016 Mar 2.

Department of Medicine, Stanford University, Stanford, CA, 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13073-016-0269-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774017PMC
March 2016

Sports genetics moving forward: lessons learned from medical research.

Physiol Genomics 2016 Mar 12;48(3):175-82. Epub 2016 Jan 12.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, California; Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University, Stanford, California; Department of Genetics, Stanford University, Stanford, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/physiolgenomics.00109.2015DOI Listing
March 2016

Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data.

PLoS Genet 2015 Oct 8;11(10):e1005496. Epub 2015 Oct 8.

Stanford Center for Inherited Cardiovascular Disease, Stanford University, Stanford, California, United States of America; Stanford Cardiovascular Institute, Stanford University, Stanford, California, United States of America; Division of Cardiovascular Medicine, Stanford University, Stanford, California, United States of America; Department of Genetics, Stanford University, Stanford, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.pgen.1005496
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1005496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598191PMC
October 2015

Spatial genomic heterogeneity within localized, multifocal prostate cancer.

Nat Genet 2015 Jul 25;47(7):736-45. Epub 2015 May 25.

1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [2] Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. [3] Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3315DOI Listing
July 2015

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection.

Nat Methods 2015 Jul 18;12(7):623-30. Epub 2015 May 18.

1] Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada. [2] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [3] Department of Pharmacology &Toxicology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth.3407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856034PMC
July 2015

Developing a prognostic micro-RNA signature for human cervical carcinoma.

PLoS One 2015 16;10(4):e0123946. Epub 2015 Apr 16.

Ontario Cancer Institute, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123946PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399941PMC
May 2016

Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway.

Mol Cell Proteomics 2014 Dec 30;13(12):3572-84. Epub 2014 Sep 30.

From the ‡Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 1L7; §Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada M5T 2M9;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M114.041764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256506PMC
December 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin.

Genes Chromosomes Cancer 2014 Oct 18;53(10):845-56. Epub 2014 Jun 18.

Department of Pathology, University Health Network, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22195DOI Listing
October 2014

A case report and genetic characterization of a massive acinic cell carcinoma of the parotid with delayed distant metastases.

Case Rep Oncol Med 2013 3;2013:270362. Epub 2013 Apr 3.

Department of Otolaryngology Head and Neck Surgery, The University of Western Ontario, Victoria Hospital, London Health Science Centre, Room B3-431A, 800 Commissioners Road East, London, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2013/270362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638544PMC
August 2013

Systematic evaluation of medium-throughput mRNA abundance platforms.

RNA 2013 Jan 20;19(1):51-62. Epub 2012 Nov 20.

Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1261/rna.034710.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527726PMC
January 2013

New susceptibility loci associated with kidney disease in type 1 diabetes.

PLoS Genet 2012 Sep 20;8(9):e1002921. Epub 2012 Sep 20.

Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum Helsinki, Helsinki, Finland.

View Article

Download full-text PDF

Source
http://pure.qub.ac.uk/portal/files/2407268/New_Susceptibilit
Web Search
http://dx.plos.org/10.1371/journal.pgen.1002921
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1002921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447939PMC
September 2012

NanoStringNorm: an extensible R package for the pre-processing of NanoString mRNA and miRNA data.

Bioinformatics 2012 Jun 17;28(11):1546-8. Epub 2012 Apr 17.

Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/bts188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356845PMC
June 2012

BR-squared: a practical solution to the winner's curse in genome-wide scans.

Hum Genet 2011 May 19;129(5):545-52. Epub 2011 Jan 19.

Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-011-0948-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074069PMC
May 2011

Transmission-ratio distortion in the Framingham Heart Study.

BMC Proc 2009 Dec 15;3 Suppl 7:S51. Epub 2009 Dec 15.

Program in Genetics and Genome Biology, Hospital for Sick Children, 101 College Street, TMDT East Tower, Toronto, ON M5G 1X8 Canada.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795951PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s51DOI Listing
December 2009

Region-based analysis in genome-wide association study of Framingham Heart Study blood lipid phenotypes.

BMC Proc 2009 Dec 15;3 Suppl 7:S127. Epub 2009 Dec 15.

Samuel Lunenfeld Research Institute of Mount Sinai Hospital, 60 Murray Street, Box 18, Toronto, Ontario M5T 3L9, Canada.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795900PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s127DOI Listing
December 2009

Genome-wide association analyses of North American Rheumatoid Arthritis Consortium and Framingham Heart Study data utilizing genome-wide linkage results.

BMC Proc 2009 Dec 15;3 Suppl 7:S103. Epub 2009 Dec 15.

Dalla Lana School of Public Health, University of Toronto, 6th Floor, Health Sciences Building, 155 College Street, Toronto, Ontario M5T 3M7 Canada.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795874PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s103DOI Listing
December 2009

Were genome-wide linkage studies a waste of time? Exploiting candidate regions within genome-wide association studies.

Genet Epidemiol 2010 Feb;34(2):107-18

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ont., Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.20438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811772PMC
February 2010