Darwin O Larco

Program in Neuroscience, Uniformed Services University of the Health Sciences, Bethesda, MD, United States; Center for Neuroscience and Regenerative Medicine, Bethesda, MD, United States; Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States. Electronic address:

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February 2017

Characterization of GPR101 transcript structure and expression patterns.

Authors:

Giampaolo Trivellin Ivana Bjelobaba Adrian F Daly Darwin O Larco Leonor Palmeira Fabio R Faucz Albert Thiry Letícia F Leal Liliya Rostomyan Martha Quezado Marie Helene Schernthaner-Reiter Marija M Janjic Chiara Villa T John Wu Stanko S Stojilkovic Albert Beckers Benjamin Feldman Constantine A Stratakis

J Mol Endocrinol 2016 08 9;57(2):97-111. Epub 2016 Jun 9.

Section on Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland, USA

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August 2016

Screening for GPR101 defects in pediatric pituitary corticotropinomas.

Authors:

Giampaolo Trivellin Ricardo R Correa Maria Batsis Fabio R Faucz Prashant Chittiboina Ivana Bjelobaba Darwin O Larco Martha Quezado Adrian F Daly Stanko S Stojilkovic T John Wu Albert Beckers Maya Lodish Constantine A Stratakis

Endocr Relat Cancer 2016 06 1;23(5):357-365. Epub 2016 Jun 1.

C Stratakis, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, United States

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June 2016

GnRH-(1-5) activates matrix metallopeptidase-9 to release epidermal growth factor and promote cellular invasion.

Authors:

Madelaine Cho-Clark Darwin O Larco Brian R Zahn Shaila K Mani T John Wu

Mol Cell Endocrinol 2015 Nov 12;415:114-25. Epub 2015 Aug 12.

Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA. Electronic address:

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November 2015

Autoshortloop feedback regulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion by its metabolite, GnRH-(1-5).

Authors:

Darwin O Larco Melissa Williams Lauren Schmidt Nick Sabel Jason Lange Michael J Woller T J Wu

Endocrine 2015 Jun 17;49(2):470-8. Epub 2014 Dec 17.

Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.

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June 2015

Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation.

Authors:

Giampaolo Trivellin Adrian F Daly Fabio R Faucz Bo Yuan Liliya Rostomyan Darwin O Larco Marie Helene Schernthaner-Reiter Eva Szarek Letícia F Leal Jean-Hubert Caberg Emilie Castermans Chiara Villa Aggeliki Dimopoulos Prashant Chittiboina Paraskevi Xekouki Nalini Shah Daniel Metzger Philippe A Lysy Emanuele Ferrante Natalia Strebkova Nadia Mazerkina Maria Chiara Zatelli Maya Lodish Anelia Horvath Rodrigo Bertollo de Alexandre Allison D Manning Isaac Levy Margaret F Keil Maria de la Luz Sierra Leonor Palmeira Wouter Coppieters Michel Georges Luciana A Naves Mauricette Jamar Vincent Bours T John Wu Catherine S Choong Jerome Bertherat Philippe Chanson Peter Kamenický William E Farrell Anne Barlier Martha Quezado Ivana Bjelobaba Stanko S Stojilkovic Jurgen Wess Stefano Costanzi Pengfei Liu James R Lupski Albert Beckers Constantine A Stratakis

N Engl J Med 2014 Dec 3;371(25):2363-74. Epub 2014 Dec 3.

The authors' affiliations are listed in the Appendix.

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December 2014

GnRH-(1-5) transactivates EGFR in Ishikawa human endometrial cells via an orphan G protein-coupled receptor.

Authors:

Madelaine Cho-Clark Darwin O Larco Nina N Semsarzadeh Florencia Vasta Shaila K Mani T John Wu

Mol Endocrinol 2014 Jan 1;28(1):80-98. Epub 2013 Jan 1.

Department of Obstetrics and Gynecology (T.J.W., M.C., F.V.) and the Program in Molecular and Cellular Biology (D.O.L., T.J.W.), Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland 20814; and Departments of Molecular and Cellular Biology and Neuroscience (S.K.M.), Baylor College of Medicine, Houston, Texas 77030.

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January 2014

β-Arrestin 2 is a mediator of GnRH-(1-5) signaling in immortalized GnRH neurons.

Authors:

Darwin O Larco Nina N Semsarzadeh Madelaine Cho-Clark Shaila K Mani T John Wu

Endocrinology 2013 Dec 18;154(12):4726-36. Epub 2013 Oct 18.

PhD, Department of Obstetrics and Gynecology, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, Maryland 20814.

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December 2013

The metabolite GnRH-(1-5) inhibits the migration of immortalized GnRH neurons.

Authors:

Darwin O Larco Madelaine Cho-Clark Shaila K Mani T John Wu

Endocrinology 2013 Feb 15;154(2):783-95. Epub 2013 Jan 15.

Program in Molecular and Cellular Biology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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February 2013

The effect of chronic immobilization stress on leptin signaling in the ovariectomized (OVX) rat.

Authors:

Darwin O Larco Danette F Cruthirds Michael J Weiser Robert J Handa T John Wu

Endocrine 2012 Dec 17;42(3):717-25. Epub 2012 Jun 17.

Program in Molecular and Cellular Biology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road # B2015, Bethesda, MD 20814, USA.

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December 2012