Darrell R Borger

Darrell R Borger

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Darrell R Borger

Darrell R Borger

Publications by authors named "Darrell R Borger"

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48Publications

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Phase II Study of Proton-Based Stereotactic Body Radiation Therapy for Liver Metastases: Importance of Tumor Genotype.

J Natl Cancer Inst 2017 09;109(9)

Department of Radiation Oncology, Department of Pathology, Division of Biostatistics, Department of Medicine, Division of Medical Oncology, Department of Medicine, Department of Radiology, and Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1093/jnci/djx031DOI Listing
September 2017

Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas.

J Neurosurg 2017 08 25;127(2):438-444. Epub 2016 Nov 25.

Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.3171/2016.8.JNS161076DOI Listing
August 2017

Biliary Adenofibroma of Liver: Morphology, Tumor Genetics, and Outcomes in 6 Cases.

Am J Surg Pathol 2017 Apr;41(4):499-505

*Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada †Massachusetts General Hospital, Boston, MA ‡Oregon Health & Science University, Portland, OR §National Institute of Health/National Cancer Institute, Rockville, MD ∥Caritas Medical Center, Kowloon, Hong Kong ¶University of Florida, Gainesville, FL #University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1097/PAS.0000000000000773DOI Listing
April 2017

Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma.

Oncologist 2016 Feb 1;21(2):214-9. Epub 2016 Feb 1.

Division of Neuro-Oncology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Division of Hematology/Oncology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1634/theoncologist.2015-0342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746092PMC
February 2016

HER2 over-expressing high grade endometrial cancer expresses high levels of p95HER2 variant.

Gynecol Oncol 2015 Apr 17;137(1):160-6. Epub 2015 Jan 17.

Vincent Center for Reproductive Biology, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, United States; Gynecologic Oncology Division, Vincent Department of Obstetrics & Gynecology, Massachusetts General Hospital, Boston, MA 02114, United States; Harvard Medical School, Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.ygyno.2015.01.533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380649PMC
April 2015

Microsatellite instability in gallbladder carcinoma.

Virchows Arch 2015 Apr 14;466(4):393-402. Epub 2015 Feb 14.

Pathology Service, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Warren 256, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00428-015-1720-0DOI Listing
April 2015

Dual HER2 targeting impedes growth of HER2 gene-amplified uterine serous carcinoma xenografts.

Clin Cancer Res 2014 Dec 7;20(24):6517-6528. Epub 2014 Oct 7.

Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, United States.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268047PMC
December 2014

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

Clin Cancer Res 2014 Jun 8;20(11):2898-909. Epub 2014 Apr 8.

Authors' Affiliations: Department of Neurosurgery; Division of Hematology/Oncology, Department of Neurology, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Translational Research Laboratory; Department of Pathology; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge; Translational Neuro-Oncology Laboratory; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts; Vesalius Research Center, VIB and Department of Oncology, KU Leuven, Leuven, BelgiumAuthors' Affiliations: Department of Neurosurgery; Division of Hematology/Oncology, Department of Neurology, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Translational Research Laboratory; Department of Pathology; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge; Translational Neuro-Oncology Laboratory; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts; Vesalius Research Center, VIB and Department of Oncology, KU Leuven, Leuven, BelgiumAuthors' Affiliations: Department of Neurosurgery; Division of Hematology/Oncology, Department of Neurology, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Translational Research Laboratory; Department of Pathology; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge; Translational Neuro-Oncology Laboratory; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts; Vesalius Research Center, VIB and Department of Oncology, KU Leuven, Leuven, Belgium

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070445PMC
June 2014

BRAF mutation in 'sarcomas': a possible method to detect de-differentiated melanomas.

Histopathology 2014 Apr 7;64(5):639-46. Epub 2013 Dec 7.

Department of Pathology, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/his.12305DOI Listing
April 2014

Inactivation of the tumor suppressor WTX in a subset of pediatric tumors.

Genes Chromosomes Cancer 2014 Jan 5;53(1):67-77. Epub 2013 Nov 5.

Department of Pathology, Massachusetts General Hospital, Boston, MA; Cancer Center, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1002/gcc.22118DOI Listing
January 2014

BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults.

J Clin Oncol 2013 May 1;31(14):e233-6. Epub 2013 Apr 1.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2012.46.0220DOI Listing
May 2013

Case records of the Massachusetts General Hospital. Case 14-2013. A 70-year-old woman with vaginal bleeding.

N Engl J Med 2013 May;368(19):1827-35

Division of Hematology and Oncology, Massachusetts General Hospital, and Department of Medicine, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1056/NEJMcpc1209276DOI Listing
May 2013

IDH mutations: new genetic signatures in cholangiocarcinoma and therapeutic implications.

Expert Rev Anticancer Ther 2012 May;12(5):543-6

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http://dx.doi.org/10.1586/era.12.32DOI Listing
May 2012

Tissue-specific signatures of activating PIK3CA and RAS mutations in carcinosarcomas of gynecologic origin.

Gynecol Oncol 2011 Apr 17;121(1):212-7. Epub 2010 Dec 17.

Vincent Center for Reproductive Biology, MGH/Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009082581000867
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http://dx.doi.org/10.1016/j.ygyno.2010.11.039DOI Listing
April 2011

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications.

PLoS One 2011 Mar 29;6(3):e17948. Epub 2011 Mar 29.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017948PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066220PMC
March 2011

A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer.

J Mol Diagn 2011 Jan 23;13(1):74-84. Epub 2010 Dec 23.

Vanderbilt-Ingram Cancer Center, the Department of Medicine/Division of Hematology-Oncology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2010.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070558PMC
January 2011

Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells.

Reprod Biol Endocrinol 2010 Dec 1;8:147. Epub 2010 Dec 1.

Vincent Center for Reproductive Biology, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1186/1477-7827-8-147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027593PMC
December 2010

Decreased survival in EGFR gene amplified vulvar carcinoma.

Gynecol Oncol 2008 Nov 3;111(2):289-97. Epub 2008 Sep 3.

Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, THR 901A, 55 Fruit Street, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1016/j.ygyno.2008.07.038DOI Listing
November 2008

AMP-activated protein kinase is essential for survival in chronic hypoxia.

Biochem Biophys Res Commun 2008 May 24;370(2):230-4. Epub 2008 Mar 24.

Dana-Farber Cancer Institute, Department of Medical Oncology, Harvard Medical School, Mayer Building 440, 44 Binney Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbrc.2008.03.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387098PMC
May 2008

Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53.

J Virol 2006 May;80(9):4292-303

Dana-Farber Cancer Institute, Department of Medical Oncology, Harvard Medical School, Mayer Building 457, 44 Binney Street, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1128/JVI.80.9.4292-4303.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472010PMC
May 2006