Dario Leosco

Dario Leosco

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Dario Leosco

Publications by authors named "Dario Leosco"

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Predisposing factors to heart failure in diabetic nephropathy: a look at the sympathetic nervous system hyperactivity.

Aging Clin Exp Res 2018 Jun 1. Epub 2018 Jun 1.

Division of Geriatrics, Department of Translational Medical Sciences, Federico II University of Naples, Via Sergio Pansini, 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s40520-018-0973-2DOI Listing
June 2018

Pressure injuries in elderly with acute myocardial infarction.

Clin Interv Aging 2017 19;12:1495-1501. Epub 2017 Sep 19.

Division of Geriatrics, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.2147/CIA.S135676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614743PMC
April 2018

Long-Term Caloric Restriction Improves Cardiac Function, Remodeling, Adrenergic Responsiveness, and Sympathetic Innervation in a Model of Postischemic Heart Failure.

Circ Heart Fail 2018 Mar;11(3):e004153

From the Division of Geriatrics, Department of Translational Medical Sciences, Federico II University of Naples, Italy (C.d.L., G.G., L.P., A.E., K.K., G.D.F., M.L.D., R.F., D. Liccardo, D. Leosco, N.F., G.R.); Center for Translational Medicine (C.d.L., D. Liccardo, W.J.K.), Department of Pharmacology (C.d.L., D. Liccardo, W.J.K.) and Cardiovascular Research Center (G.B., S.R.H.), Lewis Katz School of Medicine, Temple University, Philadelphia, PA; Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN), Italy (G.G., A.E., M.L.D., M.N., N.F., G.R.); and Neurology Imaging Unit, Imperial College London, United Kingdom (G.D.F.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858906PMC
March 2018

Adrenergic Drugs Blockers or Enhancers for Cognitive Decline ? What to Choose for Alzheimer's Disease Patients?

CNS Neurol Disord Drug Targets 2016 ;15(6):665-71

Department of Translational Medical Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131, Naples Italy.

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October 2017

Assessing Nephrological Competence among Geriatricians: A Proof of Concept Internet Survey.

PLoS One 2015 3;10(11):e0141388. Epub 2015 Nov 3.

Department of Medical, Surgical, Neurological, Aging and Metabolic Sciences, Second University of Naples, Napoli, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141388PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631491PMC
June 2016

Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart Failure.

Circ Res 2016 Apr 16;118(7):1116-24. Epub 2016 Feb 16.

From the Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN), Italy (G.R., G.G., D.F.V., N.F.); Division of Geriatrics, Department of Translational Medical Sciences (G.R., G.P., G.D.F., V.P., A.C., D. Liccardo, K.K., G.G., M.L.D.'A., C.d.L., N.F., D. Leosco), Division of Cardiology, Department of Advanced Biomedical Sciences (P.P.F., B.T.), Federico II University of Naples, Naples, Italy; SDN Foundation IRCCS, Institute of Diagnostic and Nuclear Development, Naples, Italy (S.P.); and Department of Pharmacology, Center of Translational Medicine, Temple University, Philadelphia, PA (A.C., D. Liccardo, W.J.K.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.308207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818176PMC
April 2016

Increased Epicardial Adipose Tissue Volume Correlates With Cardiac Sympathetic Denervation in Patients With Heart Failure.

Circ Res 2016 Apr 29;118(8):1244-53. Epub 2016 Feb 29.

From the Department of Translational Medical Sciences (V.P., G.R., G.P., G.D.F., L.P., G.G., A.C., N.F., D.L.) and Department of Advanced Biomedical Science (P.P.-F., T.P., A.C.), University Federico II, Naples, Italy; Department of Cardiology (G.R., G.G.) and Department of Neurology (M.N., A.E.), Salvatore Maugeri Foundation, IRCCS, Istituto di Telese, Benevento, Italy (G.R., G.G., M.N., A.E.); SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy (S.P.); Department of Cardiology and Cardiac Surgery, Casa di Cura San Michele, Maddaloni (CE), Italy (A.C., M.G.G., F.B., A.D.B.); Department of Cardiac Surgery, Ruggi D'Aragona Hospital, Salerno, Italy (E.C.); and Institute of Biostructure and Bioimaging Italian National Research Council (CNR), Naples, Italy (T.P.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307765DOI Listing
April 2016

Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases.

Nat Commun 2016 Mar 2;7:10877. Epub 2016 Mar 2.

Department of Pharmacology and Center for Translational Medicine, Temple University School of Medicine, N. Broad Street, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1038/ncomms10877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778065PMC
March 2016

β Adrenergic Receptor Kinase C-Terminal Peptide Gene-Therapy Improves β2-Adrenergic Receptor-Dependent Neoangiogenesis after Hindlimb Ischemia.

J Pharmacol Exp Ther 2016 Feb 24;356(2):503-13. Epub 2015 Nov 24.

Division of Geriatrics, Department of Translational Medical Sciences, Federico II University of Naples, Italy (A.C., D.Li., G.G., M.L.D.A., D.Le., N.F., G.R.); Center for Translational Medicine, Temple University, Philadelphia, Pennsylvania (A.C., D.Li., W.J.K.); Department of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, Florida (A.L.); Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme BN, Italy (F.R., G.R.).

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http://dx.doi.org/10.1124/jpet.115.228411DOI Listing
February 2016

Autonomic dysfunction in Alzheimer's disease: tools for assessment and review of the literature.

J Alzheimers Dis 2014 ;42(2):369-77

Department of Translational Medical Sciences, Federico II University of Naples, Naples, Italy Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese, Telese Terme (BN), Italy.

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http://dx.doi.org/10.3233/JAD-140513DOI Listing
July 2015

Impact of an Innovative Educational Strategy on Medication Appropriate Use and Length of Stay in Elderly Patients.

Medicine (Baltimore) 2015 Jun;94(24):e918

From Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy (GC, GP); Centro Medicina dell'Invecchiamento, Università Cattolica del Sacro Cuore, Rome, Italy (GG, RB); Division of Brain Sciences, Imperial College London, UK (GP); Department of Medicine and Surgery, University of Salerno, Baronissi (SA), Italy (GR, VC, AF); Department of Translational Medical Sciences, Federico II University of Naples, Naples, Italy (GR, DL, NF); and Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese, Telese Terme (BN), Italy (GR, NF).

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http://dx.doi.org/10.1097/MD.0000000000000918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616548PMC
June 2015

Adrenal adrenoceptors in heart failure.

Front Physiol 2014 7;5:246. Epub 2014 Jul 7.

Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme Telese Terme, Italy.

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http://dx.doi.org/10.3389/fphys.2014.00246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084669PMC
July 2014

Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms.

Hypertension 2014 Feb 11;63(2):404-12. Epub 2013 Nov 11.

Department of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, 3200 S University Dr, HPD Bldg/Room 1338, Fort Lauderdale, FL 33328.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889868PMC
February 2014

Sudden onset of coma in a 70-year-old woman with cryoglobulinemia.

Am J Case Rep 2014 3;15:56-9. Epub 2014 Feb 3.

Department of Translational Medical Sciences, Federico II University of Naples, Naples, Italy ; Division of Cardiology, "Salvatore Maugeri" Foundation - IRCCS - Institute of Telese Terme, Telese Terme (BN), Italy.

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http://dx.doi.org/10.12659/AJCR.889868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917880PMC
February 2014

β-adrenergic receptor responsiveness in aging heart and clinical implications.

Front Physiol 2014 Jan 9;4:396. Epub 2014 Jan 9.

Department of Translational Medical Sciences, University of Naples "Federico II" Naples, Italy.

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http://dx.doi.org/10.3389/fphys.2013.00396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885807PMC
January 2014

Effects of exercise training on cardiovascular adrenergic system.

Front Physiol 2013 Nov 28;4:348. Epub 2013 Nov 28.

Department of Translational Medical Sciences, University of Naples "Federico II," Naples, Italy.

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http://dx.doi.org/10.3389/fphys.2013.00348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842896PMC
November 2013

β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy.

Circulation 2013 Oct 22;128(15):1612-22. Epub 2013 Aug 22.

Division of Geriatrics, Department of Translational Medical Sciences (A.C., G.R., D.L., G.P., N.F., D.L.), Department of Pediatrics and European Laboratory for the Investigation of Food-Induced Diseases (M.V.B.), and Division of Cardiology, Department of Advanced Biomedical Sciences (M.C.D.A., R.P., E.D.P., P.C., B.T., A.R.), Federico II University, Naples, Italy; Center of Translational Medicine, Temple University, Philadelphia, PA (A.C., J.E.R., W.J.K.); Division of Cardiology, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN), Italy (G.R., C.Z., N.F.); and the Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom (T.M.P.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952877PMC
October 2013

Cardiovascular involvement in patients affected by acromegaly: an appraisal.

Int J Cardiol 2013 Sep 4;167(5):1712-8. Epub 2012 Dec 4.

Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2012.11.109DOI Listing
September 2013

GRK2 blockade with βARKct is essential for cardiac β2-adrenergic receptor signaling towards increased contractility.

Cell Commun Signal 2013 Aug 28;11:64. Epub 2013 Aug 28.

Department of Pharmaceutical Sciences, Laboratory for the Study of Neurohormonal Control of the Circulation, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL 33328, USA.

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http://dx.doi.org/10.1186/1478-811X-11-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846709PMC
August 2013

[Adipokines and coronary artery disease].

Monaldi Arch Chest Dis 2012 Sep;78(3):120-8

Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II, Italy.

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http://www.monaldi-archives.org/index.php/macd/article/view/
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http://dx.doi.org/10.4081/monaldi.2012.117DOI Listing
September 2012

Coronary computed tomography: current role and future perspectives for cardiovascular risk stratification.

Eur Heart J Cardiovasc Imaging 2012 Jun 20;13(6):453-8. Epub 2012 Apr 20.

Department of Internal Medicine, Cardiovascular and Immunological Sciences, Federico II University, Via S Pansini 5, Naples, Italy.

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http://dx.doi.org/10.1093/ehjci/jes081DOI Listing
June 2012

Unrestricted use of endeavor resolute zotarolimus-eluting stent in daily clinical practice: a prospective registry.

J Invasive Cardiol 2012 Jun;24(6):251-5

Department of Clinical Medicine, Cardiovascular Sciences and Immunology, Federico II University, Via S. Pansini, 5. 80131. Naples, Italy.

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June 2012

Statins and the elderly: recent evidence and current indications.

Aging Clin Exp Res 2012 Jun;24(3 Suppl):47-55

Department of Clinical Medicine and Cardiovascular and Immunology Sciences, University of Naples Federico II, via Pansini 5, 80131 Napoli, Italy.

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June 2012

[Clinical and therapeutic value of carotid intima-media thickness].

Monaldi Arch Chest Dis 2011 Sep;76(3):132-5

Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università degli Studi di Napoli Federico II, Napoli, Italia.

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http://dx.doi.org/10.4081/monaldi.2011.184DOI Listing
September 2011

[From myocardium to the atherosclerotic plaque: new perspectives in cardiologic imaging].

Monaldi Arch Chest Dis 2011 Jun;76(2):60-5

Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università degli Studi di Napoli Federico II, Italy.

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http://dx.doi.org/10.4081/monaldi.2011.190DOI Listing
June 2011

GRK2 as a novel gene therapy target in heart failure.

J Mol Cell Cardiol 2011 May 25;50(5):785-92. Epub 2010 Aug 25.

Center for Translational Medicine and George Zallie and Family Laboratory for Cardiovascular Gene Therapy, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2010.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005526PMC
May 2011

A new approach to percutaneous coronary revascularization in patients requiring undeferrable non-cardiac surgery.

Int J Cardiol 2011 Feb 22;146(3):399-403. Epub 2009 Aug 22.

Department of Clinical Medicine, Cardiovascular Science and Immunology, Federico II University, Naples, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2009.07.027DOI Listing
February 2011

An active lifestyle prior to coronary surgery is associated with improved survival in elderly patients.

J Gerontol A Biol Sci Med Sci 2010 Jul 27;65(7):758-63. Epub 2010 Jan 27.

Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Federico II University, Via Pansini 5, 80131 Naples, Italy.

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https://academic.oup.com/biomedgerontology/article-lookup/do
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http://dx.doi.org/10.1093/gerona/glp216DOI Listing
July 2010

The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance.

Cardiovasc Res 2009 Dec 20;84(3):407-15. Epub 2009 Jul 20.

Dipartimento di Medicina Clinica, Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università Federico II, Via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1093/cvr/cvp252DOI Listing
December 2009

Hypermagnesemia predicts mortality in elderly with congestive heart disease: relationship with laxative and antacid use.

Rejuvenation Res 2008 Feb;11(1):129-38

Rehabilitative Cardiology Unit of S. Maugeri Foundation, Scientific Institute of Telese/Campoli, IRCCS, Telese Terme, Italy.

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http://dx.doi.org/10.1089/rej.2007.0583DOI Listing
February 2008

Lymphocyte G-protein-coupled receptor kinase-2 is upregulated in patients with Alzheimer's disease.

Neurosci Lett 2007 Mar 19;415(3):279-82. Epub 2007 Jan 19.

Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università Federico II, Via Pansini 5, Edificio 2, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.neulet.2007.01.034DOI Listing
March 2007

Exercise training affects age-induced changes in SOD and heat shock protein expression in rat heart.

Exp Gerontol 2006 Aug 5;41(8):764-70. Epub 2006 Jul 5.

Department of Experimental Medicine and Excellence Center of Cardiovascular Disease, Second University of Naples, Naples 80138, Italy.

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http://dx.doi.org/10.1016/j.exger.2006.05.008DOI Listing
August 2006

Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure.

Eur Heart J 2005 Sep 29;26(17):1752-8. Epub 2005 Jul 29.

Department of Medicina Clinica Scienze Cardiovascolari ed Immunologiche, Federico II University, Via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1093/eurheartj/ehi429DOI Listing
September 2005

Echocardiographic evaluation of left ventricular end-systolic elastance in the elderly.

Eur J Heart Fail 2005 Aug;7(5):829-33

Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università degli Studi di Napoli Federico II, Via S. Pansini, 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.ejheart.2004.09.008DOI Listing
August 2005

Insulin-induced changes in beta-adrenergic response: an experimental study in the isolated rat papillary muscle.

Am J Hypertens 2005 Mar;18(3):348-53

Department of Health Sciences, University of Molise, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese/Campoli, Via dei Bagni Vecchi, 82037 Telese Terme, Italy.

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http://dx.doi.org/10.1016/j.amjhyper.2004.10.006DOI Listing
March 2005

Aging exacerbates negative remodeling and impairs endothelial regeneration after balloon injury.

Am J Physiol Heart Circ Physiol 2004 Dec 1;287(6):H2850-60. Epub 2004 Jul 1.

Div. of Cardiology, Magna Graecia Univ., Via Tommaso Campanella, 115, 88100 Catanzaro, Italy.

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http://dx.doi.org/10.1152/ajpheart.01119.2003DOI Listing
December 2004

[Epidemiology and risk factors for heart failure in the elderly].

Ital Heart J 2004 Dec;5 Suppl 10:9S-16S

Università degli Studi Federico II, Napoli.

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December 2004

Disability and 6-year mortality in elderly population. Role of visual impairment.

Aging Clin Exp Res 2004 Oct;16(5):382-8

Department of Rehabilitation, Salvatore Maugeri Foundation, Telese/Campoli (Bn), Italy.

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October 2004

Angiotensin II-receptor antagonist losartan does not prevent nitroglycerin tolerance in patients with coronary artery disease.

Cardiovasc Drugs Ther 2004 Sep;18(5):363-70

Division of Cardiology, Fondazione Salvatore Maugeri, IRCCS Scientific Institute of Telese Terme, Via Bagni Vecchi, 82037 Telese Termi, Italy.

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http://dx.doi.org/10.1007/s10557-005-5060-1DOI Listing
September 2004

Body mass index and preinfarction angina in elderly patients with acute myocardial infarction.

Am J Clin Nutr 2003 Oct;78(4):796-801

Cattedra di Geriatria, Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Università degli Studi di Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1093/ajcn/78.4.796DOI Listing
October 2003

Exercise restores beta-adrenergic vasorelaxation in aged rat carotid arteries.

Am J Physiol Heart Circ Physiol 2003 Jul 13;285(1):H369-74. Epub 2003 Mar 13.

Department of Clinic Medicine, University of Naples "Federico II," Via Sergio Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1152/ajpheart.00019.2003DOI Listing
July 2003

Immediate and long-term outcome of recanalization of chronic total coronary occlusions.

J Interv Cardiol 2002 Jun;15(3):173-9

Division of Cardiology, Federico II University, Via S. Pansini 5, 80131 Naples, Italy.

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June 2002