Daria Pagliara

Decolonization of multi-drug resistant bacteria by fecal microbiota transplantation in five pediatric patients before allogeneic hematopoietic stem cell transplantation: gut microbiota profiling, infectious and clinical outcomes.

Authors:

Pietro Merli Lorenza Putignani Annalisa Ruggeri Federica Del Chierico Livia Gargiullo Federica Galaverna Stefania Gaspari Daria Pagliara Alessandra Russo Stefania Pane Luisa Strocchio Mattia Algeri Francesca Rea Erminia Francesca Romeo Paola Bernaschi Andrea Onetti Muda Bruno Dallapiccola Franco Locatelli

Haematologica 2020 11 1;105(11):2686-2690. Epub 2020 Nov 1.

Dept. of Hematology/Oncology, Cellular and Gene Therapy,Bambino Gesù Children Hospital,Rome.

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November 2020

Canonical and Noncanonical Roles of Fanconi Anemia Proteins: Implications in Cancer Predisposition.

Authors:

Giacomo Milletti Luisa Strocchio Daria Pagliara Katia Girardi Roberto Carta Angela Mastronuzzi Franco Locatelli Francesca Nazio

Cancers (Basel) 2020 Sep 20;12(9). Epub 2020 Sep 20.

Department of Pediatric Hemato-Oncology and Cell and Gene Therapy, Istituto di Ricovero e Cura a Carattere Scientifico Bambino Gesù Children's Hospital, 00146 Rome, Italy.

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September 2020

Phenotypic and Functional Characterization of NK Cells in αβT-Cell and B-Cell Depleted Haplo-HSCT to Cure Pediatric Patients with Acute Leukemia.

Cancers (Basel) 2020 Aug 5;12(8). Epub 2020 Aug 5.

Laboratory of Immunology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale Policlinico San Martino, 16132 Genoa, Italy.

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August 2020

Immune Modulation Properties of Zoledronic Acid on TcRγδ T-Lymphocytes After TcRαβ/CD19-Depleted Haploidentical Stem Cell Transplantation: An analysis on 46 Pediatric Patients Affected by Acute Leukemia.

Authors:

Pietro Merli Mattia Algeri Federica Galaverna Giuseppe Maria Milano Valentina Bertaina Simone Biagini Elia Girolami Giuseppe Palumbo Matilde Sinibaldi Marco Becilli Giovanna Leone Emilia Boccieri Lavinia Grapulin Stefania Gaspari Irma Airoldi Luisa Strocchio Daria Pagliara Franco Locatelli

Front Immunol 2020 12;11:699. Epub 2020 May 12.

Department of Pediatric Hematology and Oncology and of Cell and Gene Therapy, Scientific Institute for Research and Healthcare (IRCCS), Bambino Gesù Childrens' Hospital, Rome, Italy.

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May 2020

Partial T cell defects and expanded CD56 NK cells in an SCID patient carrying hypomorphic mutation in the IL2RG gene.

Authors:

Cristina Cifaldi Nicola Cotugno Silvia Di Cesare Silvia Giliani Gigliola Di Matteo Donato Amodio Eva Piano Mortari Maria Chiriaco Danilo Buonsenso Paola Zangari Daria Pagliara Stefania Gaspari Rita Carsetti Paolo Palma Andrea Finocchi Franco Locatelli Paolo Rossi Margherita Doria Caterina Cancrini

J Leukoc Biol 2020 08 11;108(2):739-748. Epub 2020 May 11.

Unit of Immune and Infectious Diseases, Academic Department of Pediatrics, Bambino Gesù Childrens' Hospital-Scientific Institute for Research and Healthcare (IRCCS), Rome, Italy.

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August 2020

Occurrence of long-term effects after hematopoietic stem cell transplantation in children affected by acute leukemia receiving either busulfan or total body irradiation: results of an AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) retrospective study.

Authors:

Francesco Saglio Marco Zecca Daria Pagliara Giovanna Giorgiani Adriana Balduzzi Elisabetta Calore Claudio Favre Maura Faraci Arcangelo Prete Francesco Paolo Tambaro Paola Quarello Franco Locatelli Franca Fagioli

Bone Marrow Transplant 2020 Oct 29;55(10):1918-1927. Epub 2020 Jan 29.

Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, Torino, Italy.

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October 2020

Occurrence of long-term effects after hematopoietic stem cell transplantation in children affected by acute leukemia receiving either busulfan or total body irradiation: results of an AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) retrospective study.

Authors:

Francesco Saglio Marco Zecca Daria Pagliara Giovanna Giorgiani Adriana Balduzzi Elisabetta Calore Claudio Favre Maura Faraci Arcangelo Prete Francesco Paolo Tambaro Paola Quarello Franco Locatelli Franca Fagioli

Bone Marrow Transplant 2020 Oct 29;55(10):1918-1927. Epub 2020 Jan 29.

Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, Torino, Italy.

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October 2020

Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation.

Authors:

Pietro Merli Ignazio Caruana Rita De Vito Luisa Strocchio Gerrit Weber Francesca Del Bufalo Vanessa Buatois Paolo Montanari Maria Giuseppina Cefalo Angela Pitisci Mattia Algeri Federica Galaverna Concetta Quintarelli Valentina Cirillo Daria Pagliara Walter Ferlin Maria Ballabio Cristina De Min Franco Locatelli

Haematologica 2019 11 21;104(11):2314-2323. Epub 2019 Feb 21.

Bambino Ges Children's Hospital, Department of Pediatric Hematology/Oncology, Cellular and Gene Therapy, Rome, Italy.

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November 2019

Unrelated donor vs HLA-haploidentical α/β T-cell- and B-cell-depleted HSCT in children with acute leukemia.

Blood 2018 12 22;132(24):2594-2607. Epub 2018 Oct 22.

Department of Pediatric Hematology/Oncology and Cell and Gene Therapy, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Ospedale Bambino Gesù, Rome, Italy.

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December 2018

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

Cell Rep 2018 06;23(13):3946-3959.e6

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; Department of Molecular Cell Biology and Immunology, VU Medical Center, Amsterdam, the Netherlands. Electronic address:

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June 2018

Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma.

Authors:

Concetta Quintarelli Domenico Orlando Iolanda Boffa Marika Guercio Vinicia Assunta Polito Andrea Petretto Chiara Lavarello Matilde Sinibaldi Gerrit Weber Francesca Del Bufalo Ezio Giorda Marco Scarsella Stefania Petrini Daria Pagliara Franco Locatelli Biagio De Angelis Ignazio Caruana

Oncoimmunology 2018;7(6):e1433518. Epub 2018 Mar 15.

Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.

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March 2018

Novel X-Linked Inhibitor of Apoptosis Mutation in Very Early-Onset Inflammatory Bowel Disease Child Successfully Treated with HLA-Haploidentical Hemapoietic Stem Cells Transplant after Removal of αβ T and B Cells.

Authors:

Cristina Cifaldi Maria Chiriaco Gigliola Di Matteo Silvia Di Cesare Scarselli Alessia Paola De Angelis Francesca Rea Giulia Angelino Maria Pastore Valentina Ferradini Daria Pagliara Caterina Cancrini Paolo Rossi Alice Bertaina Andrea Finocchi

Front Immunol 2017 22;8:1893. Epub 2017 Dec 22.

University Department of Pediatrics, Unit of Immunology and Infectious Diseases, Bambino Gesù Children's Hospital, Rome, Italy.

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December 2017

Reconstitution of multifunctional CD56CD16 natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation.

Authors:

Helena Stabile Paolo Nisti Giovanna Peruzzi Cinzia Fionda Daria Pagliara Pomonia Letizia Brescia Pietro Merli Franco Locatelli Angela Santoni Angela Gismondi

Oncoimmunology 2017;6(9):e1342024. Epub 2017 Aug 10.

Dept. Molecular Medicine.

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August 2017

Efficacy of two different doses of rabbit anti-T-lymphocyte globulin to prevent graft-versus-host disease in children with haematological malignancies transplanted from an unrelated donor: a multicentre, randomised, open-label, phase 3 trial.

Authors:

Franco Locatelli Maria Ester Bernardo Alice Bertaina Carla Rognoni Patrizia Comoli Attilio Rovelli Andrea Pession Franca Fagioli Claudio Favre Edoardo Lanino Giovanna Giorgiani Pietro Merli Daria Pagliara Arcangelo Prete Marco Zecca

Lancet Oncol 2017 08 10;18(8):1126-1136. Epub 2017 Jul 10.

Oncoematologia Pediatrica, Fondazione IRCCS Policlinico "San Matteo", Pavia, Italy.

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August 2017

Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion.

Blood 2017 08 6;130(5):677-685. Epub 2017 Jun 6.

Immunology Research Area, IRCCS Ospedale Bambino Gesù, Rome, Italy.

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August 2017

Preservation of Antigen-Specific Functions of αβ T Cells and B Cells Removed from Hematopoietic Stem Cell Transplants Suggests Their Use As an Alternative Cell Source for Advanced Manipulation and Adoptive Immunotherapy.

Authors:

Giuseppina Li Pira Stefano Di Cecca Simone Biagini Elia Girolami Elisabetta Cicchetti Valentina Bertaina Concetta Quintarelli Ignazio Caruana Barbarella Lucarelli Pietro Merli Daria Pagliara Letizia Pomponia Brescia Alice Bertaina Mauro Montanari Franco Locatelli

Front Immunol 2017 23;8:332. Epub 2017 Mar 23.

Department of Pediatric Hematology and Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy; Department of Pediatrics, University of Pavia, Pavia, Italy.

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March 2017

Selective Depletion of αβ T Cells and B Cells for Human Leukocyte Antigen-Haploidentical Hematopoietic Stem Cell Transplantation. A Three-Year Follow-Up of Procedure Efficiency.

Authors:

Giuseppina Li Pira David Malaspina Elia Girolami Simone Biagini Elisabetta Cicchetti Gianpiero Conflitti Manuel Broglia Stefano Ceccarelli Stefania Lazzaro Daria Pagliara Antonella Meschini Alice Bertaina Mauro Montanari Franco Locatelli

Biol Blood Marrow Transplant 2016 11 9;22(11):2056-2064. Epub 2016 Aug 9.

Department of Pediatric Hematology-Oncology, IRCCS Bambino Gesù Children's Hospital, Rome, Italy; Department of Pediatric Sciences, University of Pavia, Pavia, Italy.

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November 2016

Response to comment on Multifunctional human CD56low CD16low NK cells are the prominent subset in bone marrow of both pediatric healthy donors and leukemic patients.

Authors:

Helena Stabile Paolo Nisti Daria Pagliara Franco Locatelli Angela Santoni Angela Gismondi

Haematologica 2015 Aug;100(8):e332-3

Department of Molecular Medicine, University of Rome "La Sapienza", University of Pavia, Italy

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August 2015

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes.

Authors:

Irma Airoldi Alice Bertaina Ignazia Prigione Alessia Zorzoli Daria Pagliara Claudia Cocco Raffaella Meazza Fabrizio Loiacono Barbarella Lucarelli Maria Ester Bernardo Giulia Barbarito Daniela Pende Alessandro Moretta Vito Pistoia Lorenzo Moretta Franco Locatelli

Blood 2015 Apr 22;125(15):2349-58. Epub 2015 Jan 22.

Department of Pediatric Hematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico Bambino Gesù Children's Hospital, Rome, Italy; Department of Pediatric Science, University of Pavia, Pavia, Italy.

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April 2015

Multifunctional human CD56 low CD16 low natural killer cells are the prominent subset in bone marrow of both healthy pediatric donors and leukemic patients.

Authors:

Helena Stabile Paolo Nisti Stefania Morrone Daria Pagliara Alice Bertaina Franco Locatelli Angela Santoni Angela Gismondi

Haematologica 2015 Apr 16;100(4):489-98. Epub 2015 Jan 16.

Department Molecular Medicine, University of Rome "La Sapienza" Eleonora Lorillard Spencer Cenci Foundation, Rome

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April 2015

HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders.

Blood 2014 Jul 28;124(5):822-6. Epub 2014 May 28.

Department of Pediatric Hematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico Bambino Gesù Children's Hospital, Rome, Italy; Department of Pediatrics, University of Pavia, Pavia, Italy.

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July 2014

Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells.

Authors:

Giovanni F Torelli Nadia Peragine Sara Raponi Daria Pagliara Maria S De Propris Antonella Vitale Alice Bertaina Walter Barberi Lorenzo Moretta Giuseppe Basso Angela Santoni Anna Guarini Franco Locatelli Robin Foà

Haematologica 2014 Jul 21;99(7):1248-54. Epub 2014 Mar 21.

Hematology, Department of Cellular Biotechnologies and Hematology, Sapienza University, Rome.

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July 2014

HLA-haploidentical T cell-depleted allogeneic hematopoietic stem cell transplantation in children with Fanconi anemia.

Authors:

Marco Zecca Luisa Strocchio Daria Pagliara Patrizia Comoli Alice Bertaina Giovanna Giorgiani Cesare Perotti Franco Corbella Letizia Brescia Franco Locatelli

Biol Blood Marrow Transplant 2014 Apr 22;20(4):571-6. Epub 2014 Jan 22.

Dipartimento di Oncoematologia Pediatrica, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy; Department of Pediatric Science, Università degli Studi di Pavia, Italy. Electronic address:

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April 2014

Kindlin-3-independent adhesion of neutrophils from patients with leukocyte adhesion deficiency type III.

Authors:

Edith van de Vijver Anton T J Tool Özden Sanal Mualla Çetin Sule Ünal Selin Aytac Karl Seeger Daria Pagliara Sergio Rutella Timo K van den Berg Taco W Kuijpers

J Allergy Clin Immunol 2014 Apr 15;133(4):1215-8. Epub 2013 Dec 15.

Emma Children's Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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April 2014

Interleukin-7 mediates selective expansion of tumor-redirected cytotoxic T lymphocytes (CTLs) without enhancement of regulatory T-cell inhibition.

Authors:

Serena K Perna Daria Pagliara Aruna Mahendravada Hao Liu Malcolm K Brenner Barbara Savoldo Gianpietro Dotti

Clin Cancer Res 2014 Jan 4;20(1):131-9. Epub 2013 Oct 4.

Authors' Affiliations: Center for Cell and Gene Therapy, and Departments of Pediatrics, Immunology, and Medicine, Baylor College of Medicine, Methodist Hospital and Texas Children's Hospital, Houston, Texas; Dipartimento di Ematologia ed Oncologia Pediatrica, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy.

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January 2014

A novel flow cytometry-based platelet aggregation assay.

Authors:

Iris M De Cuyper Marjolein Meinders Edith van de Vijver Dirk de Korte Leendert Porcelijn Masja de Haas Johannes A Eble Karl Seeger Sergio Rutella Daria Pagliara Taco W Kuijpers Arthur J Verhoeven Timo K van den Berg Laura Gutiérrez

Blood 2013 Mar 9;121(10):e70-80. Epub 2013 Jan 9.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, The Netherlands.

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March 2013

Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: implications for adoptive T cell-based therapies for lymphoma.

Authors:

Serena K Perna Biagio De Angelis Daria Pagliara Sayyeda T Hasan Lan Zhang Aruna Mahendravada Helen E Heslop Malcolm K Brenner Cliona M Rooney Gianpietro Dotti Barbara Savoldo

Clin Cancer Res 2013 Jan 13;19(1):106-17. Epub 2012 Nov 13.

Center for Cell and Gene Therapy, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, Houston, TX 77030, USA.

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January 2013

Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan.

Authors:

Maria Ester Bernardo Eugenia Piras Adriana Vacca Giovanna Giorgiani Marco Zecca Alice Bertaina Daria Pagliara Benedetta Contoli Rita Maria Pinto Giovanni Caocci Angela Mastronuzzi Giorgio La Nasa Franco Locatelli

Blood 2012 Jul 29;120(2):473-6. Epub 2012 May 29.

Department of Pediatric Hematology-Oncology, Istituto di Ricovero e Cura a Carattere Scientifico, Bambino Gesù Children's Hospital, Piazzale S Onofrio, Rome, Italy.

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July 2012