Daren L Knoell

Daren L Knoell

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Daren L Knoell

Publications by authors named "Daren L Knoell"

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Insufficient zinc intake enhances lung inflammation in response to agricultural organic dust exposure.

J Nutr Biochem 2019 Aug 3;70:56-64. Epub 2019 May 3.

The University of Nebraska Medical Center College of Medicine, Omaha, NE 68198. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2019.04.007DOI Listing
August 2019

Essential Role of Zinc and Zinc Transporters in Myeloid Cell Function and Host Defense against Infection.

J Immunol Res 2018 17;2018:4315140. Epub 2018 Oct 17.

Department of Pharmacy Practice, College of Pharmacy, 86120 Nebraska Medical Center Omaha, NE 68198-6120, USA.

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https://www.hindawi.com/journals/jir/2018/4315140/
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http://dx.doi.org/10.1155/2018/4315140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207864PMC
January 2019

IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae.

PLoS One 2016 6;11(9):e0161931. Epub 2016 Sep 6.

Pulmonary, Allergy, Critical Care and Sleep Medicine, Davis Heart and Lung Research Institute, Department of Internal Medicine, Ohio State University Medical Center, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161931PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012667PMC
August 2017

Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition.

PLoS One 2017 5;12(1):e0169531. Epub 2017 Jan 5.

Center for Microbial Interface Biology, The Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169531PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215883PMC
August 2017

Alveolar Epithelial Cells in Mycobacterium tuberculosis Infection: Active Players or Innocent Bystanders?

J Innate Immun 2016 18;8(1):3-14. Epub 2015 Sep 18.

Department of Microbial Infection and Immunity, College of Medicine, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1159/000439275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724319PMC
October 2016

Cadmium attenuates the macrophage response to LPS through inhibition of the NF-κB pathway.

Am J Physiol Lung Cell Mol Physiol 2016 Oct 5;311(4):L754-L765. Epub 2016 Aug 5.

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio; and Department of Pharmacy, The Ohio State College of Pharmacy, Columbus, Ohio

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http://www.physiology.org/doi/10.1152/ajplung.00022.2016
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http://dx.doi.org/10.1152/ajplung.00022.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142123PMC
October 2016

Retraction notice to "TGF-β1 regulation of human AT1 receptor mRNA splice variants harboring exon 2".

Mol Cell Endocrinol 2016 10;434:288

College of Pharmacy, Division of Pharmacology, The Ohio State University, Columbus, OH 43210, United States; Davis Heart and Lung Research Institute, The Ohio State University, DHLRI 515, 473 West 12th Avenue, Columbus, OH 43210, United States.

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http://dx.doi.org/10.1016/j.mce.2016.08.003DOI Listing
October 2016

Zinc regulates the acute phase response and serum amyloid A production in response to sepsis through JAK-STAT3 signaling.

PLoS One 2014 14;9(4):e94934. Epub 2014 Apr 14.

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, United States of America; Department of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094934PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986341PMC
May 2015

Tissue-Specific Induction of Mouse ZIP8 and ZIP14 Divalent Cation/Bicarbonate Symporters by, and Cytokine Response to, Inflammatory Signals.

Int J Toxicol 2014 05 10;33(3):246-258. Epub 2014 Apr 10.

Department of Environmental Health, Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, OH, USA

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http://dx.doi.org/10.1177/1091581814529310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193950PMC
May 2014

ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB.

Cell Rep 2013 Feb 9;3(2):386-400. Epub 2013 Feb 9.

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615478PMC
February 2013

Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA.

J Immunol 2012 Jul 6;189(1):433-43. Epub 2012 Jun 6.

Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.4049/jimmunol.1101375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381894PMC
July 2012

Cadmium-mediated toxicity of lung epithelia is enhanced through NF-κB-mediated transcriptional activation of the human zinc transporter ZIP8.

Am J Physiol Lung Cell Mol Physiol 2012 May 17;302(9):L909-18. Epub 2012 Feb 17.

Integrated Biomedical Science Graduate Program, College of Medicine, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1152/ajplung.00351.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362162PMC
May 2012

PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration.

Am J Physiol Lung Cell Mol Physiol 2012 Feb 28;302(3):L287-99. Epub 2011 Oct 28.

Department of Biomedical Engineering, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1152/ajplung.00037.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289272PMC
February 2012

Intestinal epithelium is more susceptible to cytopathic injury and altered permeability than the lung epithelium in the context of acute sepsis.

Int J Exp Pathol 2011 Oct 13;92(5):366-76. Epub 2011 Aug 13.

Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, The Ohio State University Medical Center, Columbus, OH 43210-1252, USA.

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http://dx.doi.org/10.1111/j.1365-2613.2011.00783.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174335PMC
October 2011

A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission.

Am J Clin Nutr 2011 Jun 27;93(6):1356-64. Epub 2011 Apr 27.

Division of Pulmonary, Critical Care and Sleep Medicine and Human Nutrition, The Ohio State University Medical Center, Columbus, OH 43210, USA.

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https://academic.oup.com/ajcn/article/93/6/1356/4597841
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http://dx.doi.org/10.3945/ajcn.110.008417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095505PMC
June 2011

Endothelial dysfunction and claudin 5 regulation during acrolein-induced lung injury.

Am J Respir Cell Mol Biol 2011 Apr 4;44(4):483-90. Epub 2010 Jun 4.

Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15219-3130, USA.

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http://dx.doi.org/10.1165/rcmb.2009-0391OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095921PMC
April 2011

Formyl peptide receptor ligands promote wound closure in lung epithelial cells.

Am J Respir Cell Mol Biol 2011 Mar 1;44(3):264-9. Epub 2010 Oct 1.

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, OH 43210-1252, USA.

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http://dx.doi.org/10.1165/rcmb.2010-0246RCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095929PMC
March 2011

Impact of zinc metabolism on innate immune function in the setting of sepsis.

Int J Vitam Nutr Res 2010 Oct;80(4-5):271-7

Dorothy M. Davis Heart and Lung Research Institute, and Department of Pharmacy, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1024/0300-9831/a000034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279174PMC
October 2010

Cadmium regulates the expression of the CFTR chloride channel in human airway epithelial cells.

Toxicol Sci 2010 Jul 2;116(1):349-58. Epub 2010 Apr 2.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1093/toxsci/kfq101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886859PMC
July 2010

Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-kappaB.

Am J Physiol Lung Cell Mol Physiol 2010 Jun 5;298(6):L744-54. Epub 2010 Mar 5.

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1152/ajplung.00368.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886607PMC
June 2010

A genotyping exercise for pharmacogenetics in pharmacy practice.

Am J Pharm Educ 2009 May;73(3):43

College of Pharmacy, The Davis Heart and Lung Research Institute, The Ohio State University, 473 W 12th Avenue, Columbus, OH 43210, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703267PMC
http://dx.doi.org/10.5688/aj730343DOI Listing
May 2009

Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis.

Crit Care Med 2009 Apr;37(4):1380-8

Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Medical Center, Columbus, OH, USA.

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http://pdfs.journals.lww.com/ccmjournal/2009/04000/Zinc_defi
Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/CCM.0b013e31819cefe4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905048PMC
April 2009

Inhibition of the phosphatase PTEN protects mice against oleic acid-induced acute lung injury.

Br J Pharmacol 2009 Jan;156(1):189-200

The Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1111/j.1476-5381.2008.00020.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697782PMC
January 2009

Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2.

Am J Respir Cell Mol Biol 2008 Nov 12;39(5):536-42. Epub 2008 May 12.

Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD, USA.

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http://dx.doi.org/10.1165/rcmb.2008-0059OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2574525PMC
November 2008

The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia.

Am J Physiol Lung Cell Mol Physiol 2008 Jun 4;294(6):L1127-36. Epub 2008 Apr 4.

Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, 473 W. 12th Ave., Rm. 405A, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1152/ajplung.00057.2008DOI Listing
June 2008

TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways.

Am J Physiol Lung Cell Mol Physiol 2007 Sep 29;293(3):L790-9. Epub 2007 Jun 29.

Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1152/ajplung.00099.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413071PMC
September 2007

Zinc modulates cytokine-induced lung epithelial cell barrier permeability.

Am J Physiol Lung Cell Mol Physiol 2006 Dec 14;291(6):L1132-41. Epub 2006 Jul 14.

Department of Pharmacy, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1152/ajplung.00207.2006DOI Listing
December 2006

TGF-β1 regulation of human AT1 receptor mRNA splice variants harboring exon 2.

Mol Cell Endocrinol 2006 04 28;249(1-2):21-31. Epub 2006 Feb 28.

College of Pharmacy, Division of Pharmacology, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.mce.2006.01.009DOI Listing
April 2006

Zinc modulates airway epithelium susceptibility to death receptor-mediated apoptosis.

Am J Physiol Lung Cell Mol Physiol 2006 Mar 11;290(3):L433-41. Epub 2005 Nov 11.

Davis Heart and Lung Research Institute, 500 W. 12th Ave., Parks Hall, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1152/ajplung.00341.2005DOI Listing
March 2006

Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium.

Am J Respir Cell Mol Biol 2005 Apr 30;32(4):319-25. Epub 2004 Dec 30.

Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1165/rcmb.2004-0322OCDOI Listing
April 2005

Opposing effect by cytokines on Fas-mediated apoptosis in A549 lung epithelial cells.

Am J Respir Cell Mol Biol 2002 Jan;26(1):58-66

Department of Pharmacy, Ohio State University College of Pharmacy, and Department of Internal Medicine, Ohio State University College of Medicine, Columbus, Ohio 43210, USA.

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http://www.atsjournals.org/doi/abs/10.1165/ajrcmb.26.1.4285
Publisher Site
http://dx.doi.org/10.1165/ajrcmb.26.1.4285DOI Listing
January 2002