Publications by authors named "Danxin Wang"

58Publications

SIRT1 Gene SNP rs932658 is Associated with Medication-Related Osteonecrosis of the Jaw.

J Bone Miner Res 2020 Sep 23. Epub 2020 Sep 23.

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America.

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http://dx.doi.org/10.1002/jbmr.4185DOI Listing
September 2020

Cis-acting regulatory elements regulating CYP3A4 transcription in human liver.

Pharmacogenet Genomics 2020 07;30(5):107-116

Department of Pharmacotherapy and Translational Research, College of Pharmacy, Center for Pharmacogenomics, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000402DOI Listing
July 2020

A comparison of genetic sampling methodologies for candidate-gene analyses.

J Transl Sci 2019 Jun 25;5(3). Epub 2018 Aug 25.

Department of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.15761/JTS.1000306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867604PMC
June 2019

XRCC1-mediated DNA repair is associated with progression-free survival of multiple myeloma patients after autologous stem cell transplant.

Mol Carcinog 2019 12 22;58(12):2327-2339. Epub 2019 Sep 22.

Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1002/mc.23121DOI Listing
December 2019

Ligand-Free Estrogen Receptor (ESR1) as Master Regulator for the Expression of CYP3A4 and Other Cytochrome P450 Enzymes in the Human Liver.

Mol Pharmacol 2019 10 9;96(4):430-440. Epub 2019 Aug 9.

Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida (D.W.); Department of Clinical Sciences, Bioinformatics Core Facility, University of Texas Southwestern Medical Center, Dallas, Texas (R.L.); and Mathematical Bioscience Institute, (G.R.) and Center for Pharmacogenomics, Department of Cancer Biology and Genetics, College of Medicine (W.S.), Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1124/mol.119.116897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724575PMC
October 2019

Response to the Comments on "Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Proteomics Method".

J Proteome Res 2019 03 9;18(3):1458-1459. Epub 2019 Jan 9.

Department of Clinical Pharmacy , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.8b00940DOI Listing
March 2019

CYP2D6 haplotypes with enhancer single-nucleotide polymorphism rs5758550 and rs16947 (*2 allele): implications for CYP2D6 genotyping panels.

Pharmacogenet Genomics 2019 02;29(2):39-47

Department of Cancer Biology and Genetics, Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1097/FPC.0000000000000363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441960PMC
February 2019

Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7α-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression.

Circ Genom Precis Med 2018 10;11(10):e002082

Department of Cancer Biology and Genetics, Center for Pharmacogenomics, College of Medicine, Ohio State University, Columbus (D.W., K.H., W.S.).

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https://www.ahajournals.org/doi/10.1161/CIRCGEN.118.002082
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http://dx.doi.org/10.1161/CIRCGEN.118.002082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211808PMC
October 2018

Estimation of Sobol's Sensitivity Indices under Generalized Linear Models.

Commun Stat Theory Methods 2018 20;47(21):5163-5195. Epub 2017 Nov 20.

Mathematical Bioscience Institute, The Ohio State University, 1735 Neil Ave., Columbus, OH 43210.

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http://dx.doi.org/10.1080/03610926.2017.1388397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141050PMC
November 2017

Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Based Proteomics Method.

J Proteome Res 2018 10 4;17(10):3606-3612. Epub 2018 Sep 4.

Department of Clinical Pharmacy , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.8b00620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309561PMC
October 2018

Intronic SNP in ESR1 encoding human estrogen receptor alpha is associated with brain ESR1 mRNA isoform expression and behavioral traits.

PLoS One 2017 15;12(6):e0179020. Epub 2017 Jun 15.

Center for Pharmacogenomics, Department of Cancer Biology and Genetics, College of Medicine and Public Health, Ohio State University, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179020PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472281PMC
September 2017

Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart.

Pharm Res 2017 Aug 24;34(8):1648-1657. Epub 2017 Jan 24.

Center for Pharmacogenomics and Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, 1005 BRT, 460 West 12th Ave, Columbus, Ohio, 43210, USA.

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http://dx.doi.org/10.1007/s11095-017-2102-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315374PMC
August 2017

The CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome: Genomic Architecture, Regulatory Variants, and Clinical Associations.

Hum Mutat 2017 01 7;38(1):112-119. Epub 2016 Nov 7.

Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1002/humu.23135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154896PMC
January 2017

Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus.

Pharmacogenet Genomics 2016 May;26(5):197-207

aCenter for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus, Ohio bDepartment of Clinical Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821783PMC
May 2016

CYP3A4 intronic SNP rs35599367 (CYP3A4*22) alters RNA splicing.

Pharmacogenet Genomics 2016 Jan;26(1):40-3

Center for Pharmacogenomics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674354PMC
January 2016

Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.

PLoS One 2015 2;10(9):e0136798. Epub 2015 Sep 2.

Center for Pharmacogenomics, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America; Department of Medical Genetics, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136798PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558023PMC
May 2016

Analyzing allele specific RNA expression using mixture models.

BMC Genomics 2015 Aug 1;16:566. Epub 2015 Aug 1.

Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1186/s12864-015-1749-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521363PMC
August 2015

Regulation of cholesteryl ester transfer protein expression by upstream polymorphisms: reduced expression associated with rs247616.

Pharmacogenet Genomics 2015 Aug;25(8):394-401

Department of Pharmacology, Center for Pharmacogenomics, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499003PMC
August 2015

Response to paper by Kelly et al "The opioid receptor pharmacology of GSK1521498 compared to other ligands with different effects on compulsive reward-related behaviors" published in Psychopharmacology 232, 305-314, 2014.

Psychopharmacology (Berl) 2015 Apr 6;232(8):1493-4. Epub 2015 Mar 6.

College of Medicine, The Ohio State University, Columbus, OH, USA,

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http://dx.doi.org/10.1007/s00213-015-3892-3DOI Listing
April 2015

Functional characterization of CYP2D6 enhancer polymorphisms.

Hum Mol Genet 2015 Mar 7;24(6):1556-62. Epub 2014 Nov 7.

Center for Pharmacogenomics, School of Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1093/hmg/ddu566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381757PMC
March 2015

The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.

J Pers Med 2012 Oct;2(4):175-91

Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.3390/jpm2040175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901424PMC
October 2012

Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients.

BMC Med Genomics 2012 Jul 23;5:32. Epub 2012 Jul 23.

Department of Pharmacology, Program in Pharmacogenomics, School of Biomedical Science, College of Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1186/1755-8794-5-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418550PMC
July 2012

Polymorphisms of the SAMHD1 gene are not associated with the infection and natural control of HIV type 1 in Europeans and African-Americans.

AIDS Res Hum Retroviruses 2012 Dec 1;28(12):1565-73. Epub 2012 Jun 1.

Center for Retrovirus Research, Department of Veterinary Bioscience, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1089/AID.2012.0039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505062PMC
December 2012

CYP2C9 promoter variable number tandem repeat polymorphism regulates mRNA expression in human livers.

Drug Metab Dispos 2012 May 30;40(5):884-91. Epub 2012 Jan 30.

Program in Pharmacogenomics, Department of Pharmacology, School of Medicine, The Ohio State University, 333 West 10th Ave., Columbus, OH 43210, USA.

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http://dx.doi.org/10.1124/dmd.111.044255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336799PMC
May 2012

Human N-acetyltransferase 1 *10 and *11 alleles increase protein expression through distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity.

Pharmacogenet Genomics 2011 Oct;21(10):652-64

Department of Pharmacology, Program in Pharmacogenomics, School of Biomedical Science, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283498ee9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172334PMC
October 2011

Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.

Neuropsychopharmacology 2011 Mar 8;36(4):753-62. Epub 2010 Dec 8.

Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, OH 43210-1239, USA.

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http://dx.doi.org/10.1038/npp.2010.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055737PMC
March 2011

Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms.

Eur J Hum Genet 2011 Jan 11;19(1):76-83. Epub 2010 Aug 11.

Neuroscience Graduate Studies Program, Department of Pharmacology, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1038/ejhg.2010.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995013PMC
January 2011

Allele-specific tumor spectrum in pten knockin mice.

Proc Natl Acad Sci U S A 2010 Mar 1;107(11):5142-7. Epub 2010 Mar 1.

Department of Molecular Genetics, College of Biological Sciences, Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.0912524107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841921PMC
March 2010

Genotyping panel for assessing response to cancer chemotherapy.

BMC Med Genomics 2008 Jun 11;1:24. Epub 2008 Jun 11.

Program in Pharmacogenomics, Department of Pharmacology, Comprehensive Cancer Center, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 West 10th Avenue, Columbus, OH 43210-1239, USA.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/175
Publisher Site
http://dx.doi.org/10.1186/1755-8794-1-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442111PMC
June 2008

Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement.

Blood 2008 Aug 3;112(4):1013-21. Epub 2008 Jun 3.

Department of Pharmacology, Program in Pharmacogenetics, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1182/blood-2008-03-144899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515137PMC
August 2008

Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment.

J Pharmacol Exp Ther 2007 May 31;321(2):544-52. Epub 2007 Jan 31.

Department of Pharmacology, School of Medicine and Public Health, The Ohio State University, 333 West 10th Ave., Columbus, OH 43210, USA.

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http://dx.doi.org/10.1124/jpet.106.118810DOI Listing
May 2007

Searching for polymorphisms that affect gene expression and mRNA processing: example ABCB1 (MDR1).

AAPS J 2006 Aug 18;8(3):E515-20. Epub 2006 Aug 18.

Department of Pharmacology, Program in Pharmacogenetics, College of Medicine and Public Health, The Ohio State University, 333 West 10th Ave, Graves Hall 5168, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1208/aapsj080361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761059PMC
August 2006

Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues.

Pharmacogenet Genomics 2006 Oct;16(10):735-45

Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1097/01.fpc.0000230119.34205.8aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688811PMC
October 2006

Calmodulin binding to peptides derived from the i3 loop of muscarinic receptors.

Pharm Res 2006 Apr;23(4):647-53

Department of Biopharmaceutical Sciences, School of Pharmacy, University of California, San Francisco 94143-0446, USA.

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http://dx.doi.org/10.1007/s11095-006-9784-9DOI Listing
April 2006

Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability.

Pharmacogenet Genomics 2005 Oct;15(10):693-704

Department of Pharmacology, Program in Pharmacogenomics, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA.

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October 2005

Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

J Biol Chem 2005 Sep 26;280(38):32618-24. Epub 2005 Jul 26.

Program in Pharmacogenomics, Department of Pharmacology, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1074/jbc.M504942200DOI Listing
September 2005

Calmodulin interaction with peptides from G-protein coupled receptors measured with S-Tag labeling.

Biochem Biophys Res Commun 2005 Jul;333(2):390-5

Department of Pharmacology, College of Medicine and Public Health, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.bbrc.2005.05.129DOI Listing
July 2005

Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics.

Pharmacol Ther 2005 Apr 15;106(1):19-38. Epub 2004 Dec 15.

Integrated Biomedical Sciences Graduate Program, Department of Pharmacology, College of Medicine and Public Health, The Ohio State University, 5072 Graves Hall, 333 W. 10th Avenue, Columbus, OH 43210-1239, USA.

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http://dx.doi.org/10.1016/j.pharmthera.2004.11.001DOI Listing
April 2005

Opioid receptor homo- and heterodimerization in living cells by quantitative bioluminescence resonance energy transfer.

Mol Pharmacol 2005 Jun 18;67(6):2173-84. Epub 2005 Mar 18.

Department of Pharmacology, School of Medicine and Public Health, The Ohio State University, Columbus, OH 43210, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.104.01
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http://dx.doi.org/10.1124/mol.104.010272DOI Listing
June 2005

Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities.

Life Sci 2005 Feb 8;76(13):1427-37. Epub 2004 Dec 8.

Department of Pharmacology, College of Medicine and Public Health, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.lfs.2004.10.024DOI Listing
February 2005

Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence.

J Pharmacol Exp Ther 2004 Feb 4;308(2):512-20. Epub 2003 Nov 4.

Department of Biopharmaceutical Sciences and Pharmaceutical Chemistry, Wheeler Center for Neurobiology of Addiction, University of California San Francisco,

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http://dx.doi.org/10.1124/jpet.103.054049DOI Listing
February 2004

Serum response factor activation by muscarinic receptors via RhoA. Novel pathway specific to M1 subtype involving calmodulin, calcineurin, and Pyk2.

J Biol Chem 2002 Oct 27;277(43):40789-98. Epub 2002 Aug 27.

Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry, University of California, San Francisco, CA 94143-0446, USA.

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http://dx.doi.org/10.1074/jbc.M202745200DOI Listing
October 2002

Differential effects of mu-opioid receptor ligands on Ca(2+) signaling.

J Pharmacol Exp Ther 2002 Sep;302(3):1002-12

Department of Biopharmaceutical Sciences and Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1124/jpet.302.3.1002DOI Listing
September 2002