Danny Vesprini

Danny Vesprini

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Danny Vesprini

Danny Vesprini

Publications by authors named "Danny Vesprini"

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Stereotactic Body Radiation Therapy Boost for Intermediate-Risk Prostate Cancer: A Phase 1 Dose-Escalation Study.

Int J Radiat Oncol Biol Phys 2019 Aug 16;104(5):1066-1073. Epub 2019 Apr 16.

Sunnybrook Health Sciences Centre-Odette Cancer Centre, Toronto, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2019.04.006DOI Listing
August 2019

SABR in High-Risk Prostate Cancer: Outcomes From 2 Prospective Clinical Trials With and Without Elective Nodal Irradiation.

Int J Radiat Oncol Biol Phys 2019 May 14;104(1):36-41. Epub 2018 Nov 14.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Canada; Department of Health Policy, Measurement and Evaluation, University of Toronto, Toronto, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03603016183399
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http://dx.doi.org/10.1016/j.ijrobp.2018.11.011DOI Listing
May 2019

Combining urinary DNA methylation and cell-free microRNA biomarkers for improved monitoring of prostate cancer patients on active surveillance.

Urol Oncol 2019 May 16;37(5):297.e9-297.e17. Epub 2019 Feb 16.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2019.01.031DOI Listing
May 2019

Reproducibility of PD-L1 immunohistochemistry interpretation across various types of genitourinary and head/neck carcinomas, antibody clones, and tissue types.

Hum Pathol 2018 Dec 1;82:131-139. Epub 2018 Aug 1.

Department of Laboratory Medicine and Molecular Diagnostics, Sunnybrook Health Sciences Centre, Toronto, ON, M4N 3M5, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M4N 3M5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.07.024DOI Listing
December 2018

Basal-subtype bladder tumours show a 'hot' immunophenotype.

Histopathology 2018 Nov 14;73(5):748-757. Epub 2018 Aug 14.

Department of Anatomic Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/his.13696DOI Listing
November 2018

Immune infiltrates and PD-L1 expression in treatment-naïve acinar prostatic adenocarcinoma: an exploratory analysis.

J Clin Pathol 2018 Nov 26;71(11):1023-1027. Epub 2018 Sep 26.

Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

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http://jcp.bmj.com/lookup/doi/10.1136/jclinpath-2018-205404
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http://dx.doi.org/10.1136/jclinpath-2018-205404DOI Listing
November 2018

Prospective Study of Breast Radiation Dermatitis.

Clin Breast Cancer 2018 10 15;18(5):e789-e795. Epub 2018 Mar 15.

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S15268209183000
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http://dx.doi.org/10.1016/j.clbc.2018.03.008DOI Listing
October 2018

A Systematic Review of Heart Dose in Breast Radiotherapy.

Clin Breast Cancer 2018 10 14;18(5):e819-e824. Epub 2018 Jun 14.

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2018.05.010DOI Listing
October 2018

Radiation-induced Skin Toxicity in Breast Cancer Patients: A Systematic Review of Randomized Trials.

Clin Breast Cancer 2018 10 4;18(5):e825-e840. Epub 2018 Jul 4.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2018.06.015DOI Listing
October 2018

Radiotherapy for patients with unresected locally advanced breast cancer.

Ann Palliat Med 2018 Oct 12;7(4):373-384. Epub 2018 Jun 12.

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.21037/apm.2018.05.13DOI Listing
October 2018

To prep or not to prep - that is the question: A randomized trial on the use of antiflatulent medication as part of bowel preparation for patients having image guided external beam radiation therapy to the prostate.

Pract Radiat Oncol 2018 Mar - Apr;8(2):116-122. Epub 2017 Nov 4.

Department of Radiation Therapy, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S18798500173032
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http://dx.doi.org/10.1016/j.prro.2017.10.012DOI Listing
September 2018

Early Local Recurrence in a Patient With Encapsulated Papillary Carcinoma of the Breast.

Clin Breast Cancer 2018 08 9;18(4):e447-e448. Epub 2018 May 9.

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2018.05.001DOI Listing
August 2018

"Guys Don't Have Breasts": The Lived Experience of Men Who Have BRCA Gene Mutations and Are at Risk for Male Breast Cancer.

Am J Mens Health 2018 07 5;12(4):961-972. Epub 2018 Feb 5.

1 Department of Psychology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1177/1557988317753241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131433PMC
July 2018

Developing and Evaluating Multimedia Patient Education Tools to Better Prepare Prostate-Cancer Patients for Radiotherapy Treatment (Randomized Study).

J Cancer Educ 2018 06;33(3):551-556

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada.

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http://dx.doi.org/10.1007/s13187-016-1091-5DOI Listing
June 2018

Assessment of Serum microRNA Biomarkers to Predict Reclassification of Prostate Cancer in Patients on Active Surveillance.

J Urol 2018 06 12;199(6):1475-1481. Epub 2017 Dec 12.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225347177806
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http://dx.doi.org/10.1016/j.juro.2017.12.006DOI Listing
June 2018

Re: Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance: F. Zhao, E. Olkhov-Mitsel, T. van der Kwast, J. Sykes, D. Zdravic, V. Venkateswaran, A. R. Zlotta, A. Loblaw, N. E. Fleshner, L. Klotz, D. Vesprini and B. Bapat J Urol 2017;197:335-341.

J Urol 2018 05 9;199(5):1354-1355. Epub 2018 Feb 9.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2017.10.061DOI Listing
May 2018

A retrospective review of phyllodes tumours of the breast: A single institution experience.

Breast 2018 Apr 9;38:52-57. Epub 2017 Dec 9.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2017.12.008DOI Listing
April 2018

Magnetic Resonance Imaging-Guided Adaptive Radiation Therapy: A "Game Changer" for Prostate Treatment?

Int J Radiat Oncol Biol Phys 2018 02 26;100(2):361-373. Epub 2017 Oct 26.

The Institute of Cancer Research, London, United Kingdom; The Royal Marsden National Health Service Foundation Trust, London, United Kingdom.

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http://dx.doi.org/10.1016/j.ijrobp.2017.10.020DOI Listing
February 2018

Patient-Reported Outcomes following Breast Conservation Therapy and Barriers to Referral for Partial Breast Reconstruction.

Plast Reconstr Surg 2018 01;141(1):1-9

Toronto, Ontario, Canada From the Division of Plastic and Reconstructive Surgery and the Department of Radiation Oncology, University of Toronto.

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http://dx.doi.org/10.1097/PRS.0000000000003914DOI Listing
January 2018

Palliative treatment of metastatic phyllodes tumors: a case series.

AME Case Rep 2017 21;1. Epub 2017 Dec 21.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.21037/acr.2017.12.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155564PMC
December 2017

Long non-coding RNAs: new frontiers for advancing personalized cancer medicine in prostate cancer.

Transl Androl Urol 2017 Apr;6(2):326-330

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.21037/tau.2017.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422697PMC
April 2017

Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance.

J Urol 2017 02 18;197(2):335-341. Epub 2016 Aug 18.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Pathology, University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.08.081DOI Listing
February 2017

Improving prostate cancer care collaboratively - a multidisciplinary, formal, consensus-based approach.

Can J Urol 2017 Feb;24(1):8646-8650

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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February 2017

Active Surveillance for Intermediate Risk Prostate Cancer: Survival Outcomes in the Sunnybrook Experience.

J Urol 2016 12 26;196(6):1651-1658. Epub 2016 Aug 26.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada; Institute of Health Policy, Measurement and Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.06.102DOI Listing
December 2016

Metastatic Prostate Cancer in Men Initially Treated with Active Surveillance.

J Urol 2016 May 18;195(5):1409-1414. Epub 2015 Dec 18.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; Department of Radiation Oncology (BM, DV, GG, AL), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2015.11.075DOI Listing
May 2016

Predictive Parameters of Symptomatic Hematochezia Following 5-Fraction Gantry-Based SABR in Prostate Cancer.

Int J Radiat Oncol Biol Phys 2016 Apr 23;94(5):1043-51. Epub 2015 Dec 23.

Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada; Department of Health Policy, Measurement and Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.12.010DOI Listing
April 2016

A dosimetric study of cardiac dose sparing using the reverse semi-decubitus technique for left breast and internal mammary chain irradiation.

Radiother Oncol 2016 Jan 12;118(1):187-93. Epub 2016 Jan 12.

Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2015.12.013DOI Listing
January 2016

Gleason Upgrading with Time in a Large Prostate Cancer Active Surveillance Cohort.

J Urol 2015 Jul 4;194(1):79-84. Epub 2015 Feb 4.

Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2015.01.102DOI Listing
July 2015

A prospective comparison of MRI-US fused targeted biopsy versus systematic ultrasound-guided biopsy for detecting clinically significant prostate cancer in patients on active surveillance.

J Magn Reson Imaging 2015 Jan 21;41(1):220-5. Epub 2014 Jul 21.

Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/jmri.24710DOI Listing
January 2015

Long-term follow-up of a large active surveillance cohort of patients with prostate cancer.

J Clin Oncol 2015 Jan 15;33(3):272-7. Epub 2014 Dec 15.

Laurence Klotz, Danny Vesprini, Perakaa Sethukavalan, Vibhuti Jethava, Liying Zhang, Suneil Jain, Toshihiro Yamamoto, and Andrew Loblaw, Sunnybrook Health Sciences Centre, University of Toronto; and Alexandre Mamedov, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2014.55.1192DOI Listing
January 2015

miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1.

Cancer Res 2013 Dec 21;73(23):6972-86. Epub 2013 Oct 21.

Authors' Affiliations: Sunnybrook Research Institute, Sunnybrook Health Sciences Centre; Departments of Medicine, Medical Biophysics, and Radiation Oncology, University of Toronto; and Ontario Cancer Institute, University Health Network, Toronto, Canada.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1657DOI Listing
December 2013

Reply to Monitoring of seminoma patients with serum markers.

Cancer 2013 Jul 12;119(13):2511-2. Epub 2013 Apr 12.

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http://dx.doi.org/10.1002/cncr.28005DOI Listing
July 2013

Predicting high risk disease using serum and DNA biomarkers.

Curr Opin Urol 2013 May;23(3):252-60

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MOU.0b013e32835f89b8DOI Listing
May 2013

In reply to Nieder.

Int J Radiat Oncol Biol Phys 2013 Mar;85(3):581

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http://dx.doi.org/10.1016/j.ijrobp.2012.08.012DOI Listing
March 2013

Utility of serum tumor markers during surveillance for stage I seminoma.

Cancer 2012 Nov 19;118(21):5245-50. Epub 2012 Apr 19.

Department of Radiation Oncology, Sunnybrook Odette Cancer Center, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.27539DOI Listing
November 2012

The effect of radiation technique and bladder filling on the acute toxicity of pelvic radiotherapy for localized high risk prostate cancer.

Radiother Oncol 2012 Nov 22;105(2):193-7. Epub 2012 Nov 22.

Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.radonc.2012.09.020DOI Listing
November 2012

Inverse relationship between biochemical outcome and acute toxicity after image-guided radiotherapy for prostate cancer.

Int J Radiat Oncol Biol Phys 2012 Jun 16;83(2):608-16. Epub 2011 Nov 16.

Radiation Medicine Program, Princess Margaret Hospital, University Health Network, and Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ijrobp.2011.07.019DOI Listing
June 2012

Risk of ipsilateral breast cancer in BRCA1 and BRCA2 mutation carriers.

Breast Cancer Res Treat 2011 May 9;127(1):287-96. Epub 2011 Jan 9.

Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1007/s10549-010-1336-7DOI Listing
May 2011

Comparing prostate specific antigen triggers for intervention in men with stable prostate cancer on active surveillance.

J Urol 2010 Nov 17;184(5):1942-6. Epub 2010 Sep 17.

Department of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S002253471004023
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http://dx.doi.org/10.1016/j.juro.2010.06.101DOI Listing
November 2010

No role for routine chest radiography in stage I seminoma surveillance.

Eur Urol 2010 Mar 26;57(3):474-9. Epub 2009 Jun 26.

Department of Radiation Oncology, Princess Margaret Hospital and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.eururo.2009.06.029DOI Listing
March 2010

Stage I seminoma: what should a practicing uro-oncologist do in 2009?

Int J Urol 2009 Jun 20;16(6):544-51. Epub 2009 Apr 20.

Department of Radiation Oncology, University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1442-2042.2009.02296.xDOI Listing
June 2009

Prostate delineation using CT and MRI for radiotherapy patients with bilateral hip prostheses.

Radiother Oncol 2009 Mar 31;90(3):325-30. Epub 2008 Dec 31.

Princess Margaret Hospital, Toronto, Canada.

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http://dx.doi.org/10.1016/j.radonc.2008.11.015DOI Listing
March 2009

Homologous recombination and prostate cancer: a model for novel DNA repair targets and therapies.

Radiother Oncol 2007 Jun 24;83(3):220-30. Epub 2007 May 24.

Department of Medical Biophysics, University of Toronto and Princess Margaret Hospital (University Health Network), Toronto, Canada.

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http://dx.doi.org/10.1016/j.radonc.2007.04.016DOI Listing
June 2007

Breast tissue organochlorine levels and metabolic genotypes in relation to breast cancer risk Canada.

Cancer Causes Control 2004 May;15(4):399-418

Department of Surgery, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1023/B:CACO.0000027505.32564.c2DOI Listing
May 2004

A polymorphic locus in the promoter region of the IGFBP3 gene is related to mammographic breast density.

Cancer Epidemiol Biomarkers Prev 2004 Apr;13(4):573-82

Centre for Research in Women's Health, University of Toronto, 8790 Bay Street, Toronto, Ontario, M5G 1N8 Canada.

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https://www.mcgill.ca/pollak-lab/files/pollak-lab/a_polymorp
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April 2004

Comprehensive assessment of candidate genes and serological markers for the detection of prostate cancer.

Cancer Epidemiol Biomarkers Prev 2003 Dec;12(12):1429-37

Division of Urology, Sunnybrook and Women's College Health Sciences Centre, University of Toronto, Ontario, Canada.

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https://www.mcgill.ca/assaylab/files/assaylab/097_2003_compr
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December 2003

The N314D polymorphism of galactose-1-phosphate uridyl transferase does not modify the risk of ovarian cancer.

Cancer Epidemiol Biomarkers Prev 2003 Jul;12(7):678-80

The Center for Research in Women's Health, University of Toronto, Toronto, Ontario, M5G 1N8 Canada.

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July 2003