Publications by authors named "Danny Huylebroeck"

90Publications

Zeb2 regulates the balance between retinal interneurons and Müller glia by inhibition of BMP-Smad signaling.

Dev Biol 2020 Dec 17;468(1-2):80-92. Epub 2020 Sep 17.

Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2020.09.006DOI Listing
December 2020

3D genome organization during lymphocyte development and activation.

Brief Funct Genomics 2020 03;19(2):71-82

Department of Pulmonary Medicine, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1093/bfgp/elz030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115705PMC
March 2020

Group 2 Innate Lymphoid Cells in Human Respiratory Disorders.

J Innate Immun 2020 6;12(1):47-62. Epub 2019 Feb 6.

Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands,

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http://dx.doi.org/10.1159/000496212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959098PMC
February 2019

Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation.

Sci Rep 2017 08 17;7(1):8568. Epub 2017 Aug 17.

Department of Anatomy & Neuroscience, University College Cork (UCC), Cork, Ireland.

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http://dx.doi.org/10.1038/s41598-017-08900-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561083PMC
August 2017

Differentiation of Mouse Enteric Nervous System Progenitor Cells Is Controlled by Endothelin 3 and Requires Regulation of Ednrb by SOX10 and ZEB2.

Gastroenterology 2017 04 5;152(5):1139-1150.e4. Epub 2017 Jan 5.

Institut National de la Santé et de la Recherche Médicale, Créteil, France; Université Paris-Est, Faculté de Médecine, Créteil, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085173000
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http://dx.doi.org/10.1053/j.gastro.2016.12.034DOI Listing
April 2017

Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.

Development 2016 08 6;143(15):2829-41. Epub 2016 Jul 6.

Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine and Sagol School of Neuroscience, Tel-Aviv University, Tel Aviv 69978, Israel

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http://dx.doi.org/10.1242/dev.136101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004910PMC
August 2016

Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination.

Nat Neurosci 2016 08 13;19(8):1060-72. Epub 2016 Jun 13.

Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1038/nn.4322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961522PMC
August 2016

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2.

J Exp Med 2016 05 16;213(6):897-911. Epub 2016 May 16.

Unit of Molecular and Cellular Oncology, Inflammation Research Center, Vlaams Instituut voor Biotechnologie, 9052 Ghent, Belgium Department of Biomedical Molecular Biology, Ghent University, 9000 Ghent, Belgium

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http://dx.doi.org/10.1084/jem.20151715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886362PMC
May 2016

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells.

Stem Cell Reports 2016 Jan 17;6(1):85-94. Epub 2015 Dec 17.

Department Anatomy and Embryology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands; Department Reproductive Medicine, Ghent University Hospital, Ghent 9000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720007PMC
January 2016

The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways.

Biochim Biophys Acta 2016 Feb 22;1863(2):303-13. Epub 2015 Nov 22.

Institute of Biochemistry, University of Giessen, Germany.

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http://dx.doi.org/10.1016/j.bbamcr.2015.11.020DOI Listing
February 2016

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection.

J Exp Med 2015 Nov 26;212(12):2015-25. Epub 2015 Oct 26.

Université de Lyon, 69007 Lyon, France Institut National de la Santé et de la Recherche Médicale, U1111, 69342 Lyon, France Ecole Normale Supérieure de Lyon, 69007 Lyon, France Centre International de Recherche en Infectiologie, 69007 Lyon, France Centre National de la Recherche Scientifique, UMR5308, 69342 Lyon, France

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http://dx.doi.org/10.1084/jem.20150809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647267PMC
November 2015

Smad1/5/8 are myogenic regulators of murine and human mesoangioblasts.

J Mol Cell Biol 2016 Feb 8;8(1):73-87. Epub 2015 Oct 8.

Translational Cardiomyology Laboratory, Stem Cell Biology and Embryology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium Division of Human Anatomy, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy

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http://dx.doi.org/10.1093/jmcb/mjv059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710210PMC
February 2016

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

Nat Commun 2015 Jan 7;6:5794. Epub 2015 Jan 7.

1] Vascular Cell Biology Unit, VIB Inflammation Research Center, Ghent University, Ghent B-9052, Belgium [2] Department for Biomedical Molecular Biology, Ghent University, Ghent B-9052, Belgium [3] Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre, 99 Commercial Road, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1038/ncomms6794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354161PMC
January 2015

NLS-tagging: an alternative strategy to tag nuclear proteins.

Nucleic Acids Res 2014 Dec 26;42(21). Epub 2014 Sep 26.

Department of Cell Biology, Erasmus Medical Center, Faculty building, PO Box 2040, 3000 CA Rotterdam, The Netherlands Center for Biomedical Genetics and Medical Epigenetics Consortium, Erasmus Medical Center, Faculty building, PO Box 2040, 3000 CA Rotterdam, The Netherlands Center for Biomedical Genetics, Erasmus Medical Center, Faculty building, PO Box 2040, 3000 CA Rotterdam, The Netherlands

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http://dx.doi.org/10.1093/nar/gku869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245968PMC
December 2014

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins.

Cell Mol Life Sci 2014 Sep 27;71(18):3599-609. Epub 2014 Feb 27.

Unit of Molecular and Cellular Oncology, Inflammation Research Center, VIB, Technologiepark 927, 9052, Ghent (Zwijnaarde), Belgium.

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http://dx.doi.org/10.1007/s00018-014-1589-0DOI Listing
September 2014

Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse.

Dev Biol 2014 Feb 16;386(2):419-27. Epub 2013 Dec 16.

INSERM U1016, Institut Cochin, 75014 Paris, France; CNRS UMR8104, 75014 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, 75014 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2013.12.006DOI Listing
February 2014

Four amino acids within a tandem QxVx repeat in a predicted extended α-helix of the Smad-binding domain of Sip1 are necessary for binding to activated Smad proteins.

PLoS One 2013 11;8(10):e76733. Epub 2013 Oct 11.

Laboratory of Molecular Biology (Celgen), Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, Belgium ; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076733PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795639PMC
August 2014

Aptamers and their potential to selectively target aspects of EGF, Wnt/β-catenin and TGFβ-smad family signaling.

Int J Mol Sci 2013 Mar 26;14(4):6690-719. Epub 2013 Mar 26.

Laboratory of Molecular Biology (Celgen), Department of Development and Regeneration, KU Leuven, Campus Gasthuisberg, Building Ond & Nav4 p.o.box 812, room 05.313, Stem Cell Institute, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.3390/ijms14046690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645661PMC
March 2013

Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons.

Neuron 2013 Jan;77(1):83-98

Department of Psychiatry, Neuroscience Program, and the Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco (UCSF), San Francisco, CA 94158-2324, USA.

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http://dx.doi.org/10.1016/j.neuron.2012.11.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547499PMC
January 2013

Robustness in angiogenesis: notch and BMP shaping waves.

Trends Genet 2013 Mar 30;29(3):140-9. Epub 2012 Dec 30.

Laboratory of Developmental Signaling, VIB Center for the Biology of Disease, VIB, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.tig.2012.11.008DOI Listing
March 2013

The mammalian gene function resource: the International Knockout Mouse Consortium.

Mamm Genome 2012 Oct 12;23(9-10):580-6. Epub 2012 Sep 12.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1007/s00335-012-9422-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463800PMC
October 2012

Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.

Development 2012 Sep;139(18):3343-54

Laboratory of Developmental Signaling of the VIB11 Center for the Biology of Disease, VIB, and Center for Human Genetics, KU Leuven, B-3000 Leuven, Belgium.

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http://dev.biologists.org/cgi/doi/10.1242/dev.075465
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http://dx.doi.org/10.1242/dev.075465DOI Listing
September 2012

Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.

Development 2012 Sep 25;139(17):3109-19. Epub 2012 Jul 25.

Université catholique de Louvain, Institute of Neuroscience, Laboratory of Neural Differentiation, 1200 Brussels, Belgium.

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http://dx.doi.org/10.1242/dev.078501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074251PMC
September 2012

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.

Nucleic Acids Res 2012 Sep 26;40(17):8371-80. Epub 2012 Jun 26.

School of Life Sciences, Genome Damage and Stability Centre, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.

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http://dx.doi.org/10.1093/nar/gks622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458563PMC
September 2012

Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system.

Neuron 2012 Feb;73(4):713-28

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.neuron.2011.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293152PMC
February 2012

Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades.

Dev Cell 2012 Mar 23;22(3):501-14. Epub 2012 Feb 23.

VIB11 Center for the Biology of Disease, Laboratory of Developmental Signaling, VIB and Center for Human Genetics, KU Leuven, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.devcel.2012.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544746PMC
March 2012

Amnion formation in the mouse embryo: the single amniochorionic fold model.

BMC Dev Biol 2011 Aug 1;11:48. Epub 2011 Aug 1.

Laboratory of Developmental Signaling of the Department of Molecular and Developmental Genetics, VIB, Leuven, Belgium.

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http://dx.doi.org/10.1186/1471-213X-11-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163621PMC
August 2011

Genetic interaction between Sox10 and Zfhx1b during enteric nervous system development.

Dev Biol 2010 May 4;341(2):416-28. Epub 2010 Mar 4.

INSERM U955, IMRB, Equipe 11, Creteil, F-94010, France.

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http://dx.doi.org/10.1016/j.ydbio.2010.02.036DOI Listing
May 2010

Transforming Growth Factor type beta and Smad family signaling in stem cell function.

Cytokine Growth Factor Rev 2009 Oct-Dec;20(5-6):449-58. Epub 2009 Nov 4.

Laboratory of Molecular Biology (Celgen) of the Center for Human Genetics, University of Leuven, Flanders Institute of Biotechnology (VIB), Campus Gasthuisberg, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.cytogfr.2009.10.005DOI Listing
March 2010

Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors.

Nat Neurosci 2009 Nov 18;12(11):1373-80. Epub 2009 Oct 18.

Laboratory of Molecular Biology (Celgen), Centre for Human Genetics, KULeuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/nn.2409DOI Listing
November 2009

A broken heart: a stretch too far: an overview of mouse models with mutations in stretch-sensor components.

Int J Cardiol 2008 Dec 20;131(1):33-44. Epub 2008 Aug 20.

Laboratory of Molecular Biology (Celgen), Department of Molecular and Developmental Genetics (VIB11), Flanders Institute of Biotechnology (VIB), Leuven, Belgium.

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http://dx.doi.org/10.1016/j.ijcard.2008.06.049DOI Listing
December 2008

Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex.

Hum Mol Genet 2008 Apr 8;17(8):1175-83. Epub 2008 Jan 8.

Laboratory of Molecular Biology (Celgen), Department of Human Genetics, KULeuven, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1093/hmg/ddn007DOI Listing
April 2008

Neural crest-specific removal of Zfhx1b in mouse leads to a wide range of neurocristopathies reminiscent of Mowat-Wilson syndrome.

Hum Mol Genet 2007 Jun 3;16(12):1423-36. Epub 2007 May 3.

Laboratory of Molecular Biology (Celgen), KULeuven, Herestraat 49,B-3000 Leuven, Belgium.

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http://academic.oup.com/hmg/article/16/12/1423/2355959/Neura
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http://dx.doi.org/10.1093/hmg/ddm093DOI Listing
June 2007

XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms.

Dev Biol 2007 Jun 20;306(1):34-49. Epub 2007 Mar 20.

Department of Developmental Biology, Flanders Interuniversity Institute for Biotechnology and Laboratory of Molecular Biology, Celgen, Division of Molecular and Developmental Genetics, K.U. Leuven VIB, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.ydbio.2007.02.045DOI Listing
June 2007

Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels.

Development 2006 Sep 3;133(17):3399-409. Epub 2006 Aug 3.

Department of Developmental Biology (VIB7 for Biotechnology (VIB) and Laboratory of Molecular Biology (Celgen), University of Leuven, B-3000 Leuven, Belgium.

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http://dev.biologists.org/cgi/doi/10.1242/dev.02497
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http://dx.doi.org/10.1242/dev.02497DOI Listing
September 2006

deltaEF1 and SIP1 are differentially expressed and have overlapping activities during Xenopus embryogenesis.

Dev Dyn 2006 Jun;235(6):1491-500

Department of Developmental Biology (VIB7), Flanders Interuniversity Institute for Biotechnology (VIB) and Laboratory of Molecular Biology (Celgen), University of Leuven, Campus Gasthuisberg, Leuven, Belgium.

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http://dx.doi.org/10.1002/dvdy.20727DOI Listing
June 2006

The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo.

Development 2005 Oct;132(20):4575-86

Department of Developmental Biology (VIB-07 Institute for Biotechnology (VIB), and Laboratory of Molecular Biology (Celgen), University of Leuven, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1242/dev.02043DOI Listing
October 2005

Synaptopodin and 4 novel genes identified in primary sensory neurons.

Mol Cell Neurosci 2005 Nov 1;30(3):316-25. Epub 2005 Sep 1.

Peripheral Neuropathy Group, Department of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology (VIB), Institute Born-Bunge, University of Antwerp, Universiteitsplein 1, B-2610 Antwerpen, Belgium.

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http://dx.doi.org/10.1016/j.mcn.2005.07.005DOI Listing
November 2005

Involvement of SIP1 in positioning of somite boundaries in the mouse embryo.

Dev Dyn 2005 Oct;234(2):332-8

Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1002/dvdy.20546DOI Listing
October 2005

Smicl is a novel Smad interacting protein and cleavage and polyadenylation specificity factor associated protein.

Genes Cells 2005 Sep;10(9):897-906

Department of Developmental Biology, Flanders Interuniversity Institute for Biotechnology (VIB), University of Leuven, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1111/j.1365-2443.2005.00887.xDOI Listing
September 2005

Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus.

Circ Res 2005 Aug 21;97(3):219-26. Epub 2005 Jul 21.

Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 185 S Orange Ave, MSB Room G-609, Newark, NJ 07103, USA.

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http://dx.doi.org/10.1161/01.RES.0000177862.85474.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950023PMC
August 2005

Smads and chromatin modulation.

Cytokine Growth Factor Rev 2005 Aug-Oct;16(4-5):495-512

Department of Developmental Biology (VIB7), Flanders Interuniversity Institute for Biotechnology (VIB) and Laboratory of Molecular Biology (Celgen), University of Leuven, Belgium.

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http://dx.doi.org/10.1016/j.cytogfr.2005.05.006DOI Listing
October 2005

Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors.

J Biol Chem 2005 Jul 23;280(29):27271-83. Epub 2005 May 23.

Gesellschaft für Biotechnologische Forschung, "Signal Transduction and Gene Regulation," Mascheroder Weg 1, 38124 Braunschweig, Germany.

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http://dx.doi.org/10.1074/jbc.M503368200DOI Listing
July 2005

Direct regulation of the Nrarp gene promoter by the Notch signaling pathway.

Biochem Biophys Res Commun 2004 Sep;322(2):526-34

Laboratoire d'Embryologie Moléculaire, Université Libre de Bruxelles, Institut de Biologie et de Médecine Moléculaires, rue des Profs. Jeener et Brachet 12, B-6041 Gosselies, Belgium.

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http://dx.doi.org/10.1016/j.bbrc.2004.07.157DOI Listing
September 2004

Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse.

Genesis 2003 Sep;37(1):5-11

Department of Developmental Biology (VIB 7), Flanders Interuniversity Institute for Biotechnology (VIB), and Laboratory of Molecular Biology (CELGEN), University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/gene.10219DOI Listing
September 2003

Organization of the mouse Zfhx1b gene encoding the two-handed zinc finger repressor Smad-interacting protein-1.

Genomics 2003 Oct;82(4):460-9

Department of Developmental Biology (VIB7), Flanders Interuniversity Institute for Biotechnology (VIB), University of Leuven, B-3000 Louvain, Belgium.

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http://dx.doi.org/10.1016/s0888-7543(03)00169-1DOI Listing
October 2003

Heteromeric MAPPIT: a novel strategy to study modification-dependent protein-protein interactions in mammalian cells.

Nucleic Acids Res 2003 Jul;31(14):e75

Department of Medical Protein Research VIB09, Faculty of Medicine and Health Sciences, Ghent University, Albert Baertsoenkaai 3, B-9000 Ghent, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC167658PMC
http://dx.doi.org/10.1093/nar/gng075DOI Listing
July 2003

New intracellular components of bone morphogenetic protein/Smad signaling cascades.

FEBS Lett 2003 Jul;546(1):133-9

Department of Developmental Biology (VIB7), Flanders Interuniversity Institute for Biotechnology, University of Leuven, Herestraat 49, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/s0014-5793(03)00566-0DOI Listing
July 2003

Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin.

J Biol Chem 2003 Jul 24;278(28):26135-45. Epub 2003 Apr 24.

Department of Developmental Biology (VIB7), Flanders Interuniversity Institute for Biotechnology (VIB) and Laboratory of Molecular Biology (Celgen), University of Leuven, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1074/jbc.M300597200DOI Listing
July 2003

Alzheimer-associated C allele of the promoter polymorphism -22C>T causes a critical neuron-specific decrease of presenilin 1 expression.

Hum Mol Genet 2003 Apr;12(8):869-77

Department of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.

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http://dx.doi.org/10.1093/hmg/ddg098DOI Listing
April 2003

Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome.

Am J Hum Genet 2003 Feb 9;72(2):465-70. Epub 2003 Jan 9.

Department of Developmental Biology, Flanders Interuniversity Institute for Biotechnology, and Laboratory of Molecular Biology (Celgen), University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1086/346092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC379238PMC
February 2003

Complex Smad-dependent transcriptional responses in vertebrate development and human disease.

Crit Rev Eukaryot Gene Expr 2002 ;12(2):101-18

Laboratory of Molecular Biology, University of Leuven, Belgium.

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http://dx.doi.org/10.1615/critreveukaryotgeneexpr.v12.i2.20DOI Listing
April 2003

Generation of the floxed allele of the SIP1 (Smad-interacting protein 1) gene for Cre-mediated conditional knockout in the mouse.

Genesis 2002 Feb;32(2):82-4

Laboratory of Developmental Biology, Institute for Molecular and Cellular Biology, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1002/gene.10048DOI Listing
February 2002

Dynamic regulation of Brachyury expression in the amphibian embryo by XSIP1.

Mech Dev 2002 Feb;111(1-2):37-46

Division of Developmental Biology, National Institute for Medical Research, The Ridgeway, Mill Hill, NW7 1AA, London, UK.

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http://dx.doi.org/10.1016/s0925-4773(01)00599-8DOI Listing
February 2002