Publications by authors named "Danilo Guerini"

28Publications

Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.

ACS Med Chem Lett 2019 Jun 23;10(6):887-892. Epub 2019 May 23.

Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.

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June 2019

Second generation S1P pathway modulators: research strategies and clinical developments.

Biochim Biophys Acta 2014 May 12;1841(5):745-58. Epub 2013 Nov 12.

Novartis Institutes for Biomedical Research, CH-4056 Basel, Switzerland. Electronic address:

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May 2014

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.

Nat Chem Biol 2009 Jun;5(6):428-34

Developmental & Molecular Pathways and 2Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.

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June 2009

The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. 'Protein modifications: beyond the usual suspects' review series.

EMBO Rep 2008 Aug 11;9(8):748-53. Epub 2008 Jul 11.

Autoimmunity, Transplantation and Inflammation, Novartis Pharma AG, Forum 1, Novartis Campus, Basel CH-4056, Switzerland.

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August 2008

Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors.

J Cell Biochem 2008 Aug;104(5):1660-70

Center for Proteomic Chemistry, Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, 4002 Basel, Switzerland.

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August 2008

Synthesis and immobilization of erythro-C14-omega-aminosphingosine-1-phosphate as a potential tool for affinity chromatography.

ChemMedChem 2008 Feb;3(2):356-60

Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Brunner Strasse 59, 1230 Wien, Austria.

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February 2008

Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation.

EMBO J 2007 Oct 20;26(20):4368-79. Epub 2007 Sep 20.

Autoimmunity and Transplantation, Novartis Pharma AG, Basel, Switzerland.

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October 2007

Novel GPCR screening approach: indirect identification of S1P receptor agonists in antagonist screening using a calcium assay.

J Recept Signal Transduct Res 2006 ;26(5-6):549-75

Discovery Technologies, Novartis Institutes for BioMedical Research, Basel, Switzerland.

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March 2007

Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors.

Bioorg Med Chem Lett 2007 Jan 10;17(2):491-4. Epub 2006 Oct 10.

Department of Chemistry, Université de Montréal, PO Box 6128, Station Centre-ville, Montréal, Que., Canada H3C 3J7.

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January 2007

NBD-labeled derivatives of the immunomodulatory drug FTY720 as tools for metabolism and mode of action studies.

Bioorg Med Chem Lett 2006 Jan 19;16(1):84-7. Epub 2005 Oct 19.

Novartis Institutes for BioMedical Research, Brunnerstrasse 59, A-1230 Vienna, Austria.

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January 2006