Danielle Simmons

Danielle Simmons

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Danielle Simmons

Danielle Simmons

Publications by authors named "Danielle Simmons"

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Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation.

Radiother Oncol 2019 10 25;139:4-10. Epub 2019 Jun 25.

Department of Radiation Oncology, Stanford University School of Medicine, United States; Stanford Cancer Institute, Stanford University School of Medicine, United States. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2019.06.006DOI Listing
October 2019

Receptor dependence of BDNF actions in superficial dorsal horn: relation to central sensitization and actions of macrophage colony stimulating factor 1.

J Neurophysiol 2019 Jun 17;121(6):2308-2322. Epub 2019 Apr 17.

Neuroscience and Mental Health Institute, University of Alberta , Edmonton , Canada.

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http://dx.doi.org/10.1152/jn.00839.2018DOI Listing
June 2019

Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease.

J Huntingtons Dis 2017 ;6(4):303-325

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.3233/JHD-170275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757655PMC
July 2018

Neurotrophin Receptor Signaling as a Therapeutic Target for Huntington's Disease.

CNS Neurol Disord Drug Targets 2017 ;16(3):291-302

Department of Neurology, San Francisco VAMC and UCSF, MS127, San Francisco, CA 94121. United States.

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http://dx.doi.org/10.2174/1871527315666161107093047DOI Listing
May 2018

A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth.

Neuropharmacology 2016 11 19;110(Pt A):343-361. Epub 2016 Jun 19.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2016.06.015DOI Listing
November 2016

A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.

PLoS One 2014 25;9(8):e102136. Epub 2014 Aug 25.

Department of Neurology and Neurological Sciences, Stanford University, Stanford, California, United States of America; Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102136PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143160PMC
May 2015

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.

Nat Med 2014 Jun 4;20(6):659-63. Epub 2014 May 4.

1] Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA. [2] Neuroscience Graduate Program, Stanford University School of Medicine, Stanford, California, USA. [3] Center for Tissue Regeneration, Repair and Restoration, VA Palo Alto Health Care System, Palo Alto, California, USA.

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http://www.nature.com/articles/nm.3569
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http://dx.doi.org/10.1038/nm.3569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224436PMC
June 2014

A small molecule TrkB ligand reduces motor impairment and neuropathology in R6/2 and BACHD mouse models of Huntington's disease.

J Neurosci 2013 Nov;33(48):18712-27

Department of Neurology and Neurological Sciences and Behavioral and Functional Neuroscience Laboratory, Institute for Neuro-Innovation and Translational Neurosciences, Stanford University School of Medicine, Stanford, California 94305, Department of Psychiatry, Weill Cornell Medical College, New York, New York 10021, and Department of Neurology and Laboratory for Computational Neurochemistry and Drug Discovery, Department of Veterans Affairs Medical Center and Department of Neurology, University of California, San Francisco, San Francisco, California 94121.

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http://dx.doi.org/10.1523/JNEUROSCI.1310-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841443PMC
November 2013

BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats.

Neurobiol Aging 2012 Apr 31;33(4):708-19. Epub 2010 Jul 31.

Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697-4291, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580100027
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http://dx.doi.org/10.1016/j.neurobiolaging.2010.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978788PMC
April 2012

Nitric oxidergic cells related to ejaculation in gerbil forebrain contain androgen receptor and respond to testosterone.

J Comp Neurol 2011 Apr;519(5):900-15

Department of Neurology, Stanford University School of Medicine, Stanford, California 94305-5235, USA.

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http://dx.doi.org/10.1002/cne.22557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863384PMC
April 2011

Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice.

Neurobiol Dis 2011 Feb 23;41(2):436-44. Epub 2010 Oct 23.

Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014441PMC
February 2011

Distribution of catecholaminergic and peptidergic cells in the gerbil medial amygdala, caudal preoptic area and caudal bed nuclei of the stria terminalis with a focus on areas activated at ejaculation.

J Chem Neuroanat 2011 Jan 16;41(1):13-9. Epub 2010 Nov 16.

Department of Neurobiology and Behavior, University of California, 2205 McGaugh Hall, Irvine, CA 92697-4550, USA.

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http://dx.doi.org/10.1016/j.jchemneu.2010.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004997PMC
January 2011

Structural basis of fatty acid substrate binding to cyclooxygenase-2.

J Biol Chem 2010 Jul 12;285(29):22152-63. Epub 2010 May 12.

Hauptman-Woodward Medical Research Institute, Buffalo, New York 14203, USA.

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http://dx.doi.org/10.1074/jbc.M110.119867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903402PMC
July 2010

Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization.

Nat Neurosci 2009 Aug 20;12(8):1069-73. Epub 2009 Jul 20.

Behavioral Neuroscience Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/nn.2364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752202PMC
August 2009

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice.

Proc Natl Acad Sci U S A 2009 Mar 5;106(12):4906-11. Epub 2009 Mar 5.

Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92617-4291, USA.

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http://dx.doi.org/10.1073/pnas.0811228106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660722PMC
March 2009

Blood level of brain-derived neurotrophic factor mRNA is progressively reduced in rodent models of Huntington's disease: restoration by the neuroprotective compound CEP-1347.

Mol Cell Neurosci 2008 Sep 10;39(1):1-7. Epub 2008 May 10.

Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Via Balzaretti 9, 20133 Milano, Italy.

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http://dx.doi.org/10.1016/j.mcn.2008.04.012DOI Listing
September 2008

His-311 and Arg-559 are key residues involved in fatty acid oxygenation in pathogen-inducible oxygenase.

J Biol Chem 2008 Sep 2;283(36):24962-71. Epub 2008 Jul 2.

Hauptman-Woodward Medical Research Institute, State University of New York, Buffalo, New York 14203, USA.

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http://dx.doi.org/10.1074/jbc.M804358200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529013PMC
September 2008

Context-specific sensitization of cocaine-induced locomotor activity and associated neuronal ensembles in rat nucleus accumbens.

Eur J Neurosci 2008 Jan 17;27(1):202-12. Epub 2007 Dec 17.

Behavioral Neuroscience Branch, Intramural Research Program, The National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2007.05984.xDOI Listing
January 2008

Repeated amphetamine administration outside the home cage enhances drug-induced Fos expression in rat nucleus accumbens.

Behav Brain Res 2007 Dec 21;185(2):88-98. Epub 2007 Jul 21.

Behavioral Neuroscience Branch, Intramural Research Program, The National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016643280700367
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http://dx.doi.org/10.1016/j.bbr.2007.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135552PMC
December 2007

Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease.

Glia 2007 Aug;55(10):1074-84

Department of Psychiatry and Human Behavior, University of California, Irvine, California 92697-4292, USA.

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http://dx.doi.org/10.1002/glia.20526DOI Listing
August 2007

Evidence that long-term potentiation occurs within individual hippocampal synapses during learning.

J Neurosci 2007 Jul;27(30):8031-9

Department of Anatomy and Neurobiology, University of California, Irvine, California 92617-4291, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2003-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672739PMC
July 2007

Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage.

Eur J Neurosci 2006 Aug;24(3):867-75

Behavioural Neuroscience Branch, Intramural Research Program, The National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2006.04969.xDOI Listing
August 2006

Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A.

J Neurochem 2005 Dec 7;95(5):1481-94. Epub 2005 Oct 7.

Behavioral Neuroscience Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03500.xDOI Listing
December 2005

Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia.

Exp Neurol 2003 Dec;184(2):887-903

Department of Psychiatry & Human Behavior, University of California Irvine, Irvine, CA 92612, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001448860300345
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http://dx.doi.org/10.1016/S0014-4886(03)00345-5DOI Listing
December 2003

GABA and glutamate in mating-activated cells in the preoptic area and medial amygdala of male gerbils.

J Comp Neurol 2003 May;459(3):290-300

Department of Neurobiology and Behavior, University of California, Irvine, California 92697-4550, USA.

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http://dx.doi.org/10.1002/cne.10605DOI Listing
May 2003

Projections of the posterodorsal preoptic nucleus and the lateral part of the posterodorsal medial amygdala in male gerbils, with emphasis on cells activated with ejaculation.

J Comp Neurol 2002 Feb;444(1):75-94

Department of Neurobiology and Behavior, University of California, Irvine, California 92697-4550, USA.

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http://dx.doi.org/10.1002/cne.10128DOI Listing
February 2002