Publications

No Effects of D-Cycloserine Enhancement in Exposure With Response Prevention Therapy in Panic Disorder With Agoraphobia: A Double-Blind, Randomized Controlled Trial.
J Clin Psychopharmacol 2017 Oct;37(5):531-539
From the *Department of Clinical and Health Psychology, Utrecht University, Utrecht; †GGZ Centraal, Ermelo; ‡Altrecht Academic Anxiety Disorders Centre, Utrecht; §Department of Psychiatry and EMGO+ Institute VU-MC and GGZ inGeest, Amsterdam; ∥Department of Psychiatry, Academic Medical Centre, University of Amsterdam; ¶The Netherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam; and #University Center Psychiatry, Groningen, the Netherlands.



Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome.
Am J Psychiatry 2017 Apr 4;174(4):387-396. Epub 2016 Nov 4.
From the Department of Psychiatry, University of California, San Francisco; the Department of Medicine, Vanderbilt University Medical Center, Nashville; the Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston; the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore; the Department of Psychiatry and University Health Network, University of Toronto, Toronto; the Youthdale Treatment Centres, Toronto; the Department of Psychiatry, University of Montreal, Montreal; the Yale Child Study Center and the Department of Genetics, Yale University School of Medicine, New Haven, Conn.; the Feinstein Institute for Medical Research, North Shore/Long Island Jewish Health System, Manhasset, N.Y.; the Faculty of Social and Behavioral Sciences, Utrecht University, Utrecht, The Netherlands; the Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.; the Department of Psychology, University of Denver, Denver; the Department of Psychiatry, University of Utah, Salt Lake City; the Department of Behavioral Health, Tripler Army Medical Center, Honolulu; the Departments of Neurology, Brigham and Women's Hospital and Massachusetts General Hospital, Boston; and the Department of Psychiatry, University of Florida, Gainesville.

Abnormalities in metabolite concentrations in tourette's disorder and obsessive-compulsive disorder-A proton magnetic resonance spectroscopy study.
Psychoneuroendocrinology 2017 Mar 4;77:211-217. Epub 2017 Jan 4.
Neuroscience Campus Amsterdam, VU/VUmc, Amsterdam, The Netherlands; Department of Physics & Medical Technology, VUmc, Amsterdam, The Netherlands.

Clinical decision-making in functional and hyperkinetic movement disorders.
Neurology 2017 Jan 2;88(2):118-123. Epub 2016 Dec 2.
From the Department of Neurology and Clinical Neurophysiology (S.M.A.v.d.S., A.-F.v.R., J.H.T.M.K.) and Clinical Research Unit (R.J.d.H.), Academic Medical Center, Amsterdam; Altrecht Academic Anxiety Center and Department of Clinical & Health Psychology (D.C.C.), University of Utrecht; and Department of Neurology (M.A.J.T.), University Medical Center Groningen, University of Groningen, the Netherlands.


Social disinhibition is a heritable subphenotype of tics in Tourette syndrome.
Neurology 2016 Aug 1;87(5):497-504. Epub 2016 Jul 1.
From the Department of Psychiatry (M.E.H., S.M.D., K.L.D.), University of California, San Francisco; Psychiatric and Neurodevelopmental Genetics Unit (C.I., L.O., D.L.P., E.G., D.Y., J.M.S.), Center for Human Genetics Research, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Department of Psychiatry and Behavioral Sciences (M.G.), Johns Hopkins University School of Medicine, Baltimore, MD; Department of Psychiatry (P.S.), University of Toronto and University Health Network, Youthdale Treatment Centers; Department of Psychiatry (Y.D.), University of Montreal, Canada; Yale Child Study Center (R.A.K.), Yale University School of Medicine, New Haven, CT; The Feinstein Institute for Medical Research (C.L.B.), North Shore Long Island Jewish Health System, Manhasset, NY; Faculty of Social and Behavioural Sciences (D.C.C.), Utrecht University and Altrecht Academic Anxiety Center, Utrecht, the Netherlands; Stanley Institute for Cognitive Genomics (G.J.L.), Cold Spring Harbor Laboratory, NY; School of Education (L.M.M.), American University, Washington, DC; Department of Psychiatry (W.M.M.), University of Utah, Salt Lake City; Department of Behavioral Health (P.C.L.), Tripler Army Medical Center, Honolulu, HI; Division of Cognitive and Behavioral Neurology (J.M.S.), Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Neurology (J.M.S.), Massachusetts General Hospital, Harvard Medical School, Boston, MA; and Department of Psychiatry (C.A.M.), University of Florida, Gainesville.

The relationship between tics, OC, ADHD and autism symptoms: A cross- disorder symptom analysis in Gilles de la Tourette syndrome patients and family-members.
Psychiatry Res 2016 Mar 22;237:138-46. Epub 2016 Jan 22.
Department of Clinical & Health Psychology, Faculty of Social Sciences, Utrecht University, Netherlands; Altrecht Academic Anxiety Center, Utrecht, Netherlands.

Tic symptom dimensions and their heritabilities in Tourette's syndrome.
Psychiatr Genet 2015 Jun;25(3):112-8
aInstitut de Neurosciences de la Timone INT, Marseille, France bInstitute of Neuroscience INM-6, Research Center Jülich, Jülich, Germany cDepartment of Psychiatry, VU University Medical Centre VUmc, Amsterdam dDepartment of Clinical & Health Psychology, Utrecht University eAltrecht Academic Anxiety Center, Utrecht, The Netherlands fPsychiatry, Epidemiology & Biostatistics gDepartment of Psychiatry, University of California, San Francisco, USA.


Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.
Am J Psychiatry 2015 Jan 31;172(1):82-93. Epub 2014 Oct 31.
From the Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetics Research, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston; the Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Mass.; the Department of Psychiatry, University of California, San Francisco; the Department of Neurology, Massachusetts General Hospital, Boston; the Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital, Boston; the Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago; the Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam; the Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles; the Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Md.; the Genomic and Bioinformatic Unit, Filarete Foundation, Milan, Italy; the Department of Health Sciences, Graduate School of Nephrology, University of Milan, Milan; the Toronto Western Research Institute, University Health Network, Toronto; Hospital for Sick Children, Toronto; Università Vita-Salute San Raffaele, Milan; the Herman Dana Division of Child and Adolescent Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem; Universidad de Antioquia, Universidad Pontificia Bolivariana, Medellín, Colombia; the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore; the Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; the Child Study Center and the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.; the Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil; North Shore-Long Island Jewish Medical Center and North Shore-Lo

Mild White Matter Changes in Un-medicated Obsessive-Compulsive Disorder Patients and Their Unaffected Siblings.
Front Neurosci 2015 11;9:495. Epub 2016 Jan 11.
Neuroscience Campus Amsterdam, VU/VU University Medical CenterAmsterdam, Netherlands; Department of Physics and Medical Technology, VU University Medical CenterAmsterdam, Netherlands.

Compensatory frontoparietal activity during working memory: an endophenotype of obsessive-compulsive disorder.
Biol Psychiatry 2014 Dec 1;76(11):878-87. Epub 2013 Dec 1.
Department of Psychiatry (FEdV, SJdW, VvdB, TBvR, AJLMvB, DJV, OAvdH), VU University Medical Center, Amsterdam; Neuroscience Campus Amsterdam (FEdV, SJdW, YDvdW, DJV, OAvdH), VU University, Amsterdam; Department of Anatomy and Neurosciences (YDvdW, OAvdH), VU University Medical Center, Amsterdam.


Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.
J Am Acad Child Adolesc Psychiatry 2014 Aug 24;53(8):910-9. Epub 2014 Jun 24.
Massachusetts General Hospital, Boston; Brigham and Womens Hospital, Boston; Harvard-MIT Broad Institute, Boston. Electronic address:


BDNF Val66Met modifies the risk of childhood trauma on obsessive-compulsive disorder.
J Psychiatr Res 2013 Dec 2;47(12):1857-63. Epub 2013 Sep 2.
Department of Psychiatry, Faculty of Health Sciences, University of Stellenbosch, Tygerberg, South Africa; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, University of Stellenbosch, Tygerberg, South Africa. Electronic address:

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
PLoS Genet 2013 Oct 24;9(10):e1003864. Epub 2013 Oct 24.
Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America.



Clinical relevance of comorbidity in anxiety disorders: a report from the Netherlands Study of Depression and Anxiety (NESDA).
J Affect Disord 2012 Mar 10;137(1-3):106-12. Epub 2012 Jan 10.
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.


European clinical guidelines for Tourette syndrome and other tic disorders. Part I: assessment.
Eur Child Adolesc Psychiatry 2011 Apr;20(4):155-71
Department of Clinical and Health Psychology, Utrecht University/Altrecht Academic Anxiety Outpatient Services, PO Box 80.140, 3508 TC Utrecht, The Netherlands.


The role of the COMT Val(158)Met polymorphism in the phenotypic expression of obsessive-compulsive disorder.
Am J Med Genet B Neuropsychiatr Genet 2010 Jan;153B(1):167-76
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.


Measuring obsessive-compulsive symptoms: Padua Inventory-Revised vs. Yale-Brown Obsessive Compulsive Scale.
J Anxiety Disord 2009 Aug 24;23(6):830-5. Epub 2009 Apr 24.
Department of Psychiatry, EMGO Institute University Medical Center, Academic Outpatient Clinic for Anxiety Disorders, GGZ inGeest, A.J.Ernststraat 887, Amsterdam 1081 HL, The Netherlands.

Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorder.
Arch Gen Psychiatry 2006 Nov;63(11):1225-36
Department of Psychiatry, VU University Medical Center, Graduate School of Neurosciences, and Outpatient Academic Clinic for Anxiety Disorders, GGZ Buitenamstel, Amsterdam, the Netherlands.



Threat expectancy bias and treatment outcome in patients with panic disorder and agoraphobia.
J Behav Ther Exp Psychiatry 2016 09 1;52:99-104. Epub 2016 Apr 1.
Department of Clinical Psychology, Utrecht University, Heidelberglaan 1, 3584 CS Utrecht, The Netherlands; Altrecht Academic Anxiety Centre, Nieuwe Houtenseweg 12, 3524 SH Utrecht, The Netherlands.

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