Daniele Generali

Daniele Generali

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Daniele Generali

Daniele Generali

Publications by authors named "Daniele Generali"

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Curcumin as an Adjunct Therapy and microRNA Modulator in Breast Cancer.

Curr Pharm Des 2018 ;24(2):171-177

Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

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http://dx.doi.org/10.2174/1381612824666171129203506DOI Listing
September 2019

Distinct HR expression patterns significantly affect the clinical behavior of metastatic HER2+ breast cancer and degree of benefit from novel anti-HER2 agents in the real world setting.

Int J Cancer 2019 Jul 22. Epub 2019 Jul 22.

Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

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http://dx.doi.org/10.1002/ijc.32583DOI Listing
July 2019

New-Generation Hormone Therapies in Nonmetastatic Castration-Resistant Prostate Cancer: Why, Who, When.

Clin Genitourin Cancer 2019 Jun 6;17(3):e534-e535. Epub 2019 Feb 6.

Breast Cancer Unit and Translational Research Unit, ASST Cremona, Cremona, Italy; Department of Medical, Surgery, and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1016/j.clgc.2019.01.020DOI Listing
June 2019

Avelumab in gastric cancer.

Immunotherapy 2019 Jun 6;11(9):759-768. Epub 2019 May 6.

Breast Cancer Unit, ASST Cremona, Viale Concordia 1, 26100 Cremona, Italy.

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https://www.futuremedicine.com/doi/10.2217/imt-2019-0011
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http://dx.doi.org/10.2217/imt-2019-0011DOI Listing
June 2019

Optimal primary end point in Phase II trials of immune checkpoint inhibitors for advanced solid cancers: an evolving issue.

Immunotherapy 2019 04;11(5):365-368

Department of Medical, Surgery & Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy.

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http://dx.doi.org/10.2217/imt-2018-0204DOI Listing
April 2019

Current status of androgen receptor-splice variant 7 inhibitor niclosamide in castrate-resistant prostate-cancer.

Invest New Drugs 2018 12 7;36(6):1133-1137. Epub 2018 Aug 7.

Division of Medical Oncology, Department of Onco-Hematology, IRCCS-CROB, Referral Cancer Center of Basilicata, via Padre Pio 1, 85028, Rionero in Vulture, PZ, Italy.

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http://dx.doi.org/10.1007/s10637-018-0653-2DOI Listing
December 2018

Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit.

Br J Cancer 2018 12 27;119(12):1487-1494. Epub 2018 Nov 27.

Molecular Targeting Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milano, Italy.

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http://dx.doi.org/10.1038/s41416-018-0318-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288086PMC
December 2018

Current status of PI3K-mTOR inhibition in hormone-receptor positive, HER2-negative breast cancer.

World J Clin Oncol 2018 Dec;9(8):172-179

Department of Life Sciences, University of Trieste, Trieste 34127, Italy.

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http://dx.doi.org/10.5306/wjco.v9.i8.172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314865PMC
December 2018

Familial aggregation of gastric cancer with microsatellite instability.

Acta Chir Belg 2018 Oct 3;118(5):287-293. Epub 2018 Aug 3.

a Department of Medicine, Surgery and Neurosciences, Unit of General Surgery and Surgical Oncology , University of Siena , Siena , Italy.

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http://dx.doi.org/10.1080/00015458.2017.1379789DOI Listing
October 2018

Pertuzumab therapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer.

Lancet Oncol 2018 10 11;19(10):1270-1272. Epub 2018 Sep 11.

Breast Cancer Unit and Translational Research Unit, Azienda Socio-Sanitaria Territoriale, Cremona, Cremona, Italy; Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1016/S1470-2045(18)30512-6DOI Listing
October 2018

Abemaciclib: a CDK4/6 inhibitor for the treatment of HR+/HER2- advanced breast cancer.

Drug Des Devel Ther 2018 16;12:321-330. Epub 2018 Feb 16.

Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.2147/DDDT.S137783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818877PMC
September 2018

Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer.

Cells 2018 Jul 15;7(7). Epub 2018 Jul 15.

Department of Medical, Surgery and Health Sciences, University of Trieste, 34129 Trieste, Italy; Breast Cancer Unit and Translational Research Unit, ASST Cremona, Viale Concordia 1, C.A.P. 26100 Cremona, Italy.

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http://dx.doi.org/10.3390/cells7070076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071019PMC
July 2018

Lower urinary tract infections from external beam radiation therapy in prostate cancer: A single institution experience.

Rep Pract Oncol Radiother 2018 Jul-Aug;23(4):298-299. Epub 2018 Jul 17.

Oncological Radiotherapy Operative Unit, Istituti Ospedalieri di Cremona, Cremona, Italy.

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http://dx.doi.org/10.1016/j.rpor.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084640PMC
July 2018

The prognostic value of PI3K mutational status in breast cancer: A meta-analysis.

J Cell Biochem 2018 06 1;119(6):4287-4292. Epub 2018 Mar 1.

Department of Medical, Surgical and Health Sciences, Teaching Hospital of Cattinara, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1002/jcb.26687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995110PMC
June 2018

Lenvatinib for the treatment of renal cell carcinoma.

Expert Opin Investig Drugs 2018 05 14;27(5):507-512. Epub 2018 May 14.

c Department of Medical, Surgery and Health Sciences , University of Trieste , Trieste , Italy.

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https://www.tandfonline.com/doi/full/10.1080/13543784.2018.1
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http://dx.doi.org/10.1080/13543784.2018.1472235DOI Listing
May 2018

Cell-free DNA integrity for the monitoring of breast cancer: Future perspectives?

World J Clin Oncol 2018 Apr;9(2):26-32

Department of Life Sciences, University of Trieste, Trieste 34127, Italy.

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http://dx.doi.org/10.5306/wjco.v9.i2.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893994PMC
April 2018

Association between ramucirumab-related hypertension and response to treatment in patients with metastatic gastric cancer.

Oncotarget 2018 Apr 27;9(32):22332-22339. Epub 2018 Apr 27.

Division of Medical Oncology, Department of Onco-Hematology, IRCCS-CROB, Referral Cancer Center of Basilicata, 85028 Rionero, Vulture (PZ), Italy.

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http://dx.doi.org/10.18632/oncotarget.24900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976467PMC
April 2018

Benefit of the addition of hormone therapy to neoadjuvant anthracycline-based chemotherapy for breast cancer: comparison of predicted and observed pCR.

J Cancer Res Clin Oncol 2018 Mar 17;144(3):601-606. Epub 2018 Jan 17.

Department of Obstetrics and Gynaecology, Tenon University Hospital, Paris, France.

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http://dx.doi.org/10.1007/s00432-017-2574-4DOI Listing
March 2018

Are EGFR tyrosine kinase inhibitors effective in elderly patients with EGFR-mutated non-small cell lung cancer?

Clin Exp Med 2018 Feb 8;18(1):15-20. Epub 2017 Apr 8.

Oncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1007/s10238-017-0460-7DOI Listing
February 2018

Is the fatigue an adverse event of the second generation of hormonal therapy? Data from a literature-based meta-analysis.

Med Oncol 2018 Jan 31;35(3):29. Epub 2018 Jan 31.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129, Trieste, Italy.

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http://dx.doi.org/10.1007/s12032-018-1081-zDOI Listing
January 2018

Influence of Prior Tyrosine Kinase Inhibitor on Survival for Patients with Metastatic Renal Cell Carcinoma Treated with Nivolumab or Cabozantinib: Data from a Literature-based Meta-analysis.

Eur Urol 2017 12 29;72(6):1027-1028. Epub 2017 Jul 29.

Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy; Breast Cancer Unit and Translational Research Unit, ASST Cremona, Cremona, Italy.

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http://dx.doi.org/10.1016/j.eururo.2017.07.019DOI Listing
December 2017

Response rate as a potential surrogate for survival and efficacy in patients treated with novel immune checkpoint inhibitors: A meta-regression of randomised prospective studies.

Eur J Cancer 2017 11 19;86:257-265. Epub 2017 Oct 19.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy; Breast Cancer Unit and Translational Research Unit, ASST Cremona, Viale Concordia 1, 26100 Cremona, Italy.

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http://dx.doi.org/10.1016/j.ejca.2017.09.018DOI Listing
November 2017

Could gonadotropin-releasing hormone analogs be helpful in the treatment of triple-negative breast cancer?

Future Oncol 2017 Nov 10;13(27):2473-2477. Epub 2017 Nov 10.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, Trieste, 34129, Italy.

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http://dx.doi.org/10.2217/fon-2017-0272DOI Listing
November 2017

Advances in systemic therapy for malignant mesothelioma: future perspectives.

Future Oncol 2017 Oct 6;13(23):2083-2101. Epub 2017 Oct 6.

Department of Medical, Surgical, & Health Sciences, University of Trieste, Piazza Ospitale 1 34129 Trieste, Italy.

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http://dx.doi.org/10.2217/fon-2017-0224DOI Listing
October 2017

Bevacizumab in small cell lung cancer.

Ann Transl Med 2017 Sep;5(17):361

Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.21037/atm.2017.06.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599295PMC
September 2017

Risk of hypertension with ramucirumab-based therapy in solid tumors: data from a literature based meta-analysis.

Invest New Drugs 2017 08 11;35(4):518-523. Epub 2017 Mar 11.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129, Trieste, Italy.

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http://dx.doi.org/10.1007/s10637-017-0452-1DOI Listing
August 2017

PAK6-Associated Support Vector Machine Classifier: A New Way to Evaluate Response and Survival of Gastric Cancer Treated by 5-FU/Oxaliplatin Chemotherapy.

EBioMedicine 2017 08 5;22:18-19. Epub 2017 Jul 5.

Department of Medical, Surgery & Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy; Medical Oncology Unit, Department of Oncology, San Donato Hospital, Via Nenni 20, 52100 Arezzo, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552208PMC
August 2017

Isolated Testicular Metastasis from Prostate Cancer.

Am J Case Rep 2017 Aug 14;18:887-889. Epub 2017 Aug 14.

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567765PMC
http://dx.doi.org/10.12659/ajcr.904521DOI Listing
August 2017

Low dose versus standard dose of corticosteroids in the management of adverse events of special interest from abiraterone acetate: data from a literature-based meta-analysis.

Med Oncol 2017 Aug 29;34(10):166. Epub 2017 Aug 29.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129, Trieste, Italy.

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http://dx.doi.org/10.1007/s12032-017-1028-9DOI Listing
August 2017

Circulating tumor cells correlate with patterns of recurrence in patients with hormone-sensitive prostate cancer.

Onco Targets Ther 2017 31;10:3811-3815. Epub 2017 Jul 31.

Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.2147/OTT.S143020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546825PMC
July 2017

Single Center Experience on Anatomy-and Histopathology-Based Gastric Cancer Molecular Classification.

Cancer Invest 2017 May 28;35(5):325-332. Epub 2017 Mar 28.

a General Surgery and Surgical Oncology Department , University of Siena , Siena , Italy.

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http://dx.doi.org/10.1080/07357907.2017.1292519DOI Listing
May 2017

Is still there a place for orteronel in management of prostate cancer? Data from a literature based meta-analysis of randomized trials.

Crit Rev Oncol Hematol 2017 May 28;113:18-21. Epub 2017 Feb 28.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy; Unit of Molecular Therapy and Pharmacogenomic, ASST Cremona, Viale Concordia 1, 26100 Cremona, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2017.02.023DOI Listing
May 2017

Cost-effectiveness and sustainability of breast cancer screening and new anti-cancer drugs.

J Med Econ 2017 Apr 16;20(4):405-408. Epub 2017 Feb 16.

a University of Trieste , Trieste , Italy.

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http://dx.doi.org/10.1080/13696998.2017.1285306DOI Listing
April 2017

The role of bevacizumab in solid tumours: A literature based meta-analysis of randomised trials.

Eur J Cancer 2017 04 24;75:245-258. Epub 2017 Feb 24.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy; Unit of Molecular Therapy and Pharmacogenomic, ASST Cremona, Viale Concordia 1, 26100 Cremona, Italy.

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http://dx.doi.org/10.1016/j.ejca.2017.01.026DOI Listing
April 2017

CDK4/6 inhibitors in HER2-positive breast cancer.

Crit Rev Oncol Hematol 2017 Apr 24;112:208-214. Epub 2017 Feb 24.

Azienda Ospedaliera di Cremona, U.O. Multidisciplinare di Patologia Mammaria, U.S. Terapia Molecolare e Farmacogenomica, Cremona, Italy; Universita degli Studi di Trieste, Department of Medical, Surgery and Health Sciences, Trieste, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2017.02.022DOI Listing
April 2017

Tumor-infiltrating lymphocytes and breast cancer: Beyond the prognostic and predictive utility.

Tumour Biol 2017 Apr;39(4):1010428317695023

1 UO Multidisciplinare di Patologia Mammaria, US Terapia Molecolare e Farmacogenomica, AO Azienda Istituti Ospitalieri di Cremona, Cremona, Italy.

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http://dx.doi.org/10.1177/1010428317695023DOI Listing
April 2017

Targeting VEGFR-2 in Metastatic Gastric Cancer: Results From a Literature-Based Meta-Analysis.

Cancer Invest 2017 Mar 6;35(3):187-194. Epub 2017 Feb 6.

b Unit of Molecular Therapy and Pharmacogenomic, ASST Cremona , Cremona , Italy.

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http://dx.doi.org/10.1080/07357907.2016.1276185DOI Listing
March 2017

Cyclin dependent kinase 4 and 6 inhibitors as novel therapeutic agents for targeted treatment of malignant mesothelioma.

Genes Cancer 2017 Mar;8(3-4):495-496

Department of Medical, Surgery & Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.18632/genesandcancer.138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489646PMC
March 2017

Is still there a role for IL-2 for solid tumors other than melanoma or renal cancer?

Immunotherapy 2017 01;9(1):25-32

Unit of Molecular Therapy & Pharmacogenomics, ASST Cremona, Viale Concordia 1, 26100 Cremona, Italy.

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http://dx.doi.org/10.2217/imt-2016-0107DOI Listing
January 2017

New molecular therapies in patients with advanced Hepatocellular Cancer in second line of treatment: Is a real defeat?: Results from a literature based meta-analysis of randomized trials.

Crit Rev Oncol Hematol 2016 Dec 29;108:62-68. Epub 2016 Oct 29.

Unit of Molecular Therapy and Pharmacogenomic, ASST Cremona, Viale Concordia 1, 26100 Cremona, Italy; Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2016.10.015DOI Listing
December 2016

Is there a Place for Bevacizumab in Patients with Extensive-Stage Small Cell Lung Cancer?

Curr Cancer Drug Targets 2016 ;16(3):209-14

Department of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11 - 25123 Brescia, Italy.

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November 2016

Targeting the androgenic pathway in elderly patients with castration-resistant prostate cancer: A meta-analysis of randomized trials.

Medicine (Baltimore) 2016 Oct;95(43):e4636

aSection of Pharmacology and University Center DIFF-Drug Innovation Forward Future, Department of Molecular and Translational Medicine, University of Brescia, Brescia bU.S. Terapia Molecolare e Farmacogenomica cRadiotherapy Department, ASST Cremona, Cremona dSection of Experimental Oncology, Department of Clinical and Experimental Medicine, University of Parma, Parma eUnit of General Medicine, Azienda Ospedaliera "C. Poma" Presidio Ospedaliero di Pieve di Coriano, Mantova fDepartment of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1097/MD.0000000000004636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089083PMC
October 2016

Apatinib in metastatic gastric cancer: can paclitaxel make the difference?

Anticancer Drugs 2016 09;27(8):809

aDepartment of Molecular and Translational Medicine, University of Brescia, Brescia bUnit of Molecular Therapy and Pharmacogenomic, AO Azienda Istituti Ospitalieri di Cremona, Viale Concordia, Cremona cUnit of General and Minimally Invasive Surgery, Surgery and Neuroscience; University of Siena, Viale Bracci, Siena dDepartment of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale, Trieste, Italy.

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http://dx.doi.org/10.1097/CAD.0000000000000380DOI Listing
September 2016

No Advantage in Survival With Targeted Therapies as Maintenance in Patients With Limited and Extensive-Stage Small Cell Lung Cancer: A Literature-Based Meta-Analysis of Randomized Trials.

Clin Lung Cancer 2016 09 2;17(5):334-340. Epub 2016 Jun 2.

US Terapia Molecolare e Farmacogenomica, Azienda Socio-Sanitaria Territoriale di Cremona, Cremona, Italy; Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1016/j.cllc.2016.05.008DOI Listing
September 2016

Role of targeted agents in neuroendocrine tumors: Results from a meta-analysis.

Cancer Biol Ther 2016 09 14;17(9):883-8. Epub 2016 Jul 14.

b Unit of Molecular Therapy and Pharmacogenomic , AO Azienda Istituti Ospitalieri di Cremona , Cremona , Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036406PMC
http://dx.doi.org/10.1080/15384047.2016.1210735DOI Listing
September 2016

Re: Karim Fizazi, Kim N. Chi, Johann S. de Bono, et al. Low Incidence of Corticosteroid-associated Adverse Events on Long-term Exposure to Low-dose Prednisone Given with Abiraterone Acetate to Patients with Metastatic Castration-resistant Prostate Cancer. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2016.02.035: Corticosteroid-associated Adverse Events in Elderly Patients.

Eur Urol 2016 08 12;70(2):e41. Epub 2016 May 12.

Unit of Molecular Therapy and Pharmacogenomics, AO Azienda Istituti Ospitalieri di Cremona, Cremona, Italy; Department of Medical, Surgery, and Health Sciences, University of Trieste, Piazza Ospitale, Trieste, Italy.

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http://dx.doi.org/10.1016/j.eururo.2016.05.004DOI Listing
August 2016

Is it time for everolimus-based combination in castration-resistant prostate cancer?

Future Oncol 2016 Aug 2;12(16):1849-52. Epub 2016 Jun 2.

Unit of Molecular Therapy & Pharmacogenomic, AO Azienda Istituti Ospitalieri di Cremona, Viale Concordia 1, 26100 Cremona, Italy.

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http://dx.doi.org/10.2217/fon-2016-0136DOI Listing
August 2016

Apatinib for the treatment of gastric cancer.

Expert Rev Gastroenterol Hepatol 2016 Aug 15;10(8):887-92. Epub 2016 Jul 15.

b Unit of Molecular Therapy and Pharmacogenomic , ASST Cremona , Cremona , Italy.

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http://dx.doi.org/10.1080/17474124.2016.1209407DOI Listing
August 2016

Role of the novel generation of androgen receptor pathway targeted agents in the management of castration-resistant prostate cancer: A literature based meta-analysis of randomized trials.

Eur J Cancer 2016 07 7;61:111-21. Epub 2016 May 7.

Molecular Therapy and Pharmacogenomic Unit, ASST di Cremona, Viale Concordia 1, 26100, Cremona, Italy; Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129, Trieste, Italy.

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http://dx.doi.org/10.1016/j.ejca.2016.04.002DOI Listing
July 2016

Neoadjuvant chemotherapy and radical radiotherapy associated with cetuximab for laryngeal cancer in a pancreas and renal recipient.

Anticancer Drugs 2016 Jun;27(5):470-3

aRadiotherapy Department, ASST Cremona bUnit of Molecular Therapy and Pharmacogenomics, ASST Cremona cDepartment of Molecular and Translational Medicine, Section of Pharmacology and University Center DIFF-Drug Innovation Forward Future, University of Brescia, Brescia dDepartment of Medical, Surgery, and Health Sciences, University of Trieste, Piazza Ospitale 1, Trieste, Italy.

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http://dx.doi.org/10.1097/CAD.0000000000000352DOI Listing
June 2016

A Phase Ib Open-Label Study to Assess the Safety and Tolerability of Everolimus in Combination With Eribulin in Triple-Negative Breast Cancers.

Clin Breast Cancer 2016 Jun 11;16(3):e57-9. Epub 2016 Feb 11.

Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2016.02.012DOI Listing
June 2016

Epirubicin-based compared with docetaxel-based chemotherapy for advanced gastric carcinoma: A systematic review and meta-analysis.

Crit Rev Oncol Hematol 2016 Jun 8;102:82-8. Epub 2016 Apr 8.

Unit of Molecular Therapy and Pharmacogenomic, AO Azienda Istituti Ospitalieri di Cremona, Viale Concordia 1, 26100 Cremona, Italy; Department of Medical, Surgical and Neurosciences, Section of Advanced Surgical Oncology, University of Siena, Viale Bracci 11, 53100, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2016.04.001DOI Listing
June 2016

Incidence and relative risk of adverse events of special interest in patients with castration resistant prostate cancer treated with CYP-17 inhibitors: A meta-analysis of published trials.

Crit Rev Oncol Hematol 2016 May 27;101:12-20. Epub 2016 Feb 27.

Unit of molecular therapy and pharmacogenomic, AO Azienda Istituti Ospitalieri di Cremona, Viale Concordia 1, 26100 Cremona, Italy; Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2016.02.013DOI Listing
May 2016

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for treatment of ovarian cancer.

Int J Hyperthermia 2016 05 17;32(3):298-310. Epub 2016 Mar 17.

a Unit of General and Minimally Invasive Surgery, Surgery and Neuroscience , University of Sienna , Sienna ;

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https://www.researchgate.net/profile/Domenico_Iusco/publicat
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http://dx.doi.org/10.3109/02656736.2016.1149233DOI Listing
May 2016

Apatinib: A novel receptor tyrosine kinase inhibitor for the treatment of gastric cancer.

Cancer Lett 2016 Mar 18;372(2):187-91. Epub 2016 Jan 18.

Unit of Molecular Therapy and Pharmacogenomic, AO Azienda Istituti Ospitalieri di Cremona, Viale Concordia 1, 26100 Cremona, Italy; Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy.

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http://dx.doi.org/10.1016/j.canlet.2016.01.014DOI Listing
March 2016

Differential expression of immunohistochemical markers in primary lung and breast cancers enriched for triple-negative tumours.

Histopathology 2016 Feb 7;68(3):367-77. Epub 2015 Aug 7.

Department of Pathology, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/his.12765DOI Listing
February 2016

Current challenges in HER2-positive breast cancer.

Crit Rev Oncol Hematol 2016 Feb 31;98:211-21. Epub 2015 Oct 31.

Facoltà di Medicina e Psicologia "Sapienza" Università di Roma, Ospedale Sant'Andrea & IDI - I.R.C.C.S., Roma, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2015.10.016DOI Listing
February 2016

Monoclonal antibodies-based treatment in gastric cancer: current status and future perspectives.

Tumour Biol 2016 Jan 13;37(1):127-40. Epub 2015 Nov 13.

Department of Medical, Surgical and Neuroscience; Unit of General and Minimally Invasive Surgery, University of Siena, Viale Bracci 11, 53100, Siena, Italy.

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http://dx.doi.org/10.1007/s13277-015-4408-9DOI Listing
January 2016

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition.

Oncotarget 2016 Jan;7(1):255-65

Molecular Targeting Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.18632/oncotarget.6353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807996PMC
January 2016

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Authors:
Keith I Block Charlotte Gyllenhaal Leroy Lowe Amedeo Amedei A R M Ruhul Amin Amr Amin Katia Aquilano Jack Arbiser Alexandra Arreola Alla Arzumanyan S Salman Ashraf Asfar S Azmi Fabian Benencia Dipita Bhakta Alan Bilsland Anupam Bishayee Stacy W Blain Penny B Block Chandra S Boosani Thomas E Carey Amancio Carnero Marianeve Carotenuto Stephanie C Casey Mrinmay Chakrabarti Rupesh Chaturvedi Georgia Zhuo Chen Helen Chen Sophie Chen Yi Charlie Chen Beom K Choi Maria Rosa Ciriolo Helen M Coley Andrew R Collins Marisa Connell Sarah Crawford Colleen S Curran Charlotta Dabrosin Giovanna Damia Santanu Dasgupta Ralph J DeBerardinis William K Decker Punita Dhawan Anna Mae E Diehl Jin-Tang Dong Q Ping Dou Janice E Drew Eyad Elkord Bassel El-Rayes Mark A Feitelson Dean W Felsher Lynnette R Ferguson Carmela Fimognari Gary L Firestone Christian Frezza Hiromasa Fujii Mark M Fuster Daniele Generali Alexandros G Georgakilas Frank Gieseler Michael Gilbertson Michelle F Green Brendan Grue Gunjan Guha Dorota Halicka William G Helferich Petr Heneberg Patricia Hentosh Matthew D Hirschey Lorne J Hofseth Randall F Holcombe Kanya Honoki Hsue-Yin Hsu Gloria S Huang Lasse D Jensen Wen G Jiang Lee W Jones Phillip A Karpowicz W Nicol Keith Sid P Kerkar Gazala N Khan Mahin Khatami Young H Ko Omer Kucuk Rob J Kulathinal Nagi B Kumar Byoung S Kwon Anne Le Michael A Lea Ho-Young Lee Terry Lichtor Liang-Tzung Lin Jason W Locasale Bal L Lokeshwar Valter D Longo Costas A Lyssiotis Karen L MacKenzie Meenakshi Malhotra Maria Marino Maria L Martinez-Chantar Ander Matheu Christopher Maxwell Eoin McDonnell Alan K Meeker Mahya Mehrmohamadi Kapil Mehta Gregory A Michelotti Ramzi M Mohammad Sulma I Mohammed D James Morre Vinayak Muralidhar Irfana Muqbil Michael P Murphy Ganji Purnachandra Nagaraju Rita Nahta Elena Niccolai Somaira Nowsheen Carolina Panis Francesco Pantano Virginia R Parslow Graham Pawelec Peter L Pedersen Brad Poore Deepak Poudyal Satya Prakash Mark Prince Lizzia Raffaghello Jeffrey C Rathmell W Kimryn Rathmell Swapan K Ray Jörg Reichrath Sarallah Rezazadeh Domenico Ribatti Luigi Ricciardiello R Brooks Robey Francis Rodier H P Vasantha Rupasinghe Gian Luigi Russo Elizabeth P Ryan Abbas K Samadi Isidro Sanchez-Garcia Andrew J Sanders Daniele Santini Malancha Sarkar Tetsuro Sasada Neeraj K Saxena Rodney E Shackelford H M C Shantha Kumara Dipali Sharma Dong M Shin David Sidransky Markus David Siegelin Emanuela Signori Neetu Singh Sharanya Sivanand Daniel Sliva Carl Smythe Carmela Spagnuolo Diana M Stafforini John Stagg Pochi R Subbarayan Tabetha Sundin Wamidh H Talib Sarah K Thompson Phuoc T Tran Hendrik Ungefroren Matthew G Vander Heiden Vasundara Venkateswaran Dass S Vinay Panagiotis J Vlachostergios Zongwei Wang Kathryn E Wellen Richard L Whelan Eddy S Yang Huanjie Yang Xujuan Yang Paul Yaswen Clement Yedjou Xin Yin Jiyue Zhu Massimo Zollo

Semin Cancer Biol 2015 Dec;35 Suppl:S276-S304

Centro di Ingegneria Genetica e Biotecnologia Avanzate, Naples, Italy; Department of Molecular Medicine and Medical Biotechnology, Federico II, Via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.semcancer.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819002PMC
December 2015

Ibrutinib: from bench side to clinical implications.

Med Oncol 2015 Sep 30;32(9):225. Epub 2015 Jul 30.

Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1007/s12032-015-0669-9DOI Listing
September 2015

Prospective Biomarker Analysis of the Randomized CHER-LOB Study Evaluating the Dual Anti-HER2 Treatment With Trastuzumab and Lapatinib Plus Chemotherapy as Neoadjuvant Therapy for HER2-Positive Breast Cancer.

Oncologist 2015 Sep 5;20(9):1001-10. Epub 2015 Aug 5.

Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy; Division of Medical Oncology 2, Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy; Division of Oncology, University Hospital, Ferrara, Italy; Division of Pathology, Modena University Hospital, Modena, Italy; Center for Genome Research, University of Modena and Reggio Emilia, Modena, Italy; Unità Operativa Multidisciplinare di Patologia Mammaria, Azienda Ospedaliera Istituti Ospitalieri di Cremona, Cremona, Italy; Division of Medical Oncology, Ramazzini Hospital, Carpi, Italy; Department of Medical Oncology, Azienda Ospedaliera ASMN, IRCCS, Reggio Emilia, Italy; Division of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS, Meldola, Italy; Division of Medical Oncology, University Hospital, Parma, Italy; GlaxoSmithKline, Collegeville, Pennsylvania, USA

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http://dx.doi.org/10.1634/theoncologist.2015-0138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571802PMC
September 2015

Breast cancer circulating biomarkers: advantages, drawbacks, and new insights.

Tumour Biol 2015 Sep 26;36(9):6653-65. Epub 2015 Aug 26.

U.O. Multidisciplinare di Patologia Mammaria, U.S. Terapia Molecolare e Farmacogenomica, AZ. Istituti Ospitalieri di Cremona, Viale Concordia 1, 26100, Cremona, Italy.

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http://dx.doi.org/10.1007/s13277-015-3944-7DOI Listing
September 2015

Would the combination of everolimus with endocrine-therapy help in FGFR2 positive serous endometrial cancer?

Oncoscience 2015 5;2(6):567-9. Epub 2015 Jun 5.

U.S. Terapia Molecolare e Farmacogenomica, AO Azienda Istituti Ospitalieri di Cremona, Cremona, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506357PMC
http://dx.doi.org/10.18632/oncoscience.168DOI Listing
August 2015

Neoadjuvant Model in Cancer Treatment: From Clinical Opportunity to Health-Care Utility.

J Natl Cancer Inst Monogr 2015 May;2015(51):1-3

U.O. Multidisciplinare di Patologia Mammaria, U.S Terapia Molecolare e Farmacogenomica (DG, AB), Direzione Sanitaria (CR), A.O. Istituti Ospitalieri di Cremona, Cremona, Italy (DG, AB); Department of Anatomical Pathology, Peter MacCallum Cancer Centre, East Melbourne, Australia (SBF); Thomas Jefferson University Hospital, Philadelphia, PA (MC); San Raffaele - Scientific Institute, Milan, Italy (GB); Medical Oncology, Department of Oncology and Hematology, Papa Giovanni XXIII Hospital, Bergamo, Italy (AZ); Section of Medical Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT (CH); Division of Pathology, European Institute of Oncology, Milan, Italy (MB); Department of Policy Analysis and Public Management, Research Center on Health and Social Care Management, CERGAS, SDA Bocconi School of Management, Bocconi University, Milan, Italy (RT); Health Technology Assessment - Regione Lombardia, Italy (MT).

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http://dx.doi.org/10.1093/jncimonographs/lgv022DOI Listing
May 2015

Neoadjuvant Treatment Approach: The Rosetta Stone for Breast Cancer?

J Natl Cancer Inst Monogr 2015 May;2015(51):32-5

U.O. Multidisciplinare di Patologia Mammaria, U.S Terapia Molecolare e Farmacogenomica, A.O. Istituti Ospitalieri di Cremona, Cremona, Italy (DG, MA, CS, MMi, MRC, LZ, MF, FB, MMa, ABo); U.O. Oncologia Medica, Spedali Civili si Brescia, Brescia, Italy (VA, ES, ABe); Section of Pharmacology, Department of Molecular and Translational Medicine, University of Brescia Medical School, Brescia, Italy (FB, SS).

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http://dx.doi.org/10.1093/jncimonographs/lgv019DOI Listing
May 2015

Effect of Primary Letrozole Treatment on Tumor Expression of mTOR and HIF-1α and Relation to Clinical Response.

J Natl Cancer Inst Monogr 2015 May;2015(51):64-6

U.O. Multidisciplinare di Patologia Mammaria/ US Terapia Molecolare (DG, MRC, LZ, GB, MF, FB, MEV, MM, CS, MA, SA, GA, ABo), and Anatomia Patologica (GF, RB), Azienda Istituti Ospitalieri di Cremona, Cremona, Italy; Oncologia Medica, Università di Brescia, Spedali Civili di Brescia, Brescia, Italy (ABe, GB); Weatherall Molecular Oncology Laboratories, Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK (ALH); Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Australia (SBF).

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http://dx.doi.org/10.1093/jncimonographs/lgv018DOI Listing
May 2015

High-Dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplantation for High-Risk Primary Breast Cancer.

J Natl Cancer Inst Monogr 2015 May;2015(51):70-5

SC Oncologia, Dipartimento Onco-ematologico, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy (PP, SD); Ematologia con Trapianto di Midollo Osseo e Terapia Intensiva, Azienda Ospedaliera Bianchi-Melacrino-Morelli, Reggio Calabria, Italy (MM); US Terapia Molecolare e Farmacogenomica/UO Patologia Mammaria, Azienda Istituti Ospitalieri di Cremona, Cremona, Italy (DG); SC Oncologia Medica, Ospedale S. Maria di Ca' Foncello, Treviso, Italy (GR); SC Oncologia Medica, Dipartimento di Oncologia, Ospedale di Circolo, Busto Arsizio (Va), Italy (MB); Sezione di Ematologia e CTMO, Azienda Istituti Ospitalieri di Cremona, Cremona, Italy (FL).

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http://dx.doi.org/10.1093/jncimonographs/lgv010DOI Listing
May 2015

RNA Disruption and Drug Response in Breast Cancer Primary Systemic Therapy.

J Natl Cancer Inst Monogr 2015 May;2015(51):76-80

Rna Diagnostics Inc, Toronto, ON, Canada (KP, LP, AP); Department of Laboratory Medicine and Pathobiology and Department of Surgery, University of Toronto, Toronto, ON, Canada (KP, MT); Unita di Patologia Mammaria, Breasteast Unit, Azienda Ospedaliera Istituti Ospitaieri di Cremona, Cremona, Italy (DG, AB, MRC); Advanced Medical Research Institute of Canada, Sudbury, ON, Canada (BG, AP); Laurentian University, Sudbury ON, Canada (AP); Odette Cancer Centre, Sunnybrook Hospital, Toronto, ON, Canada (MT).

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http://dx.doi.org/10.1093/jncimonographs/lgv015DOI Listing
May 2015

International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fifth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2013).

J Natl Cancer Inst Monogr 2015 May;2015(51):90-6

Medical Oncology Unit (VA, ABe), University of Brescia, and Breast Unit (RP, LV, ELS) Spedali Civili Hospital, Brescia, Italy; U.O. Multidisciplinare di Patologia Mammaria, S.S. Terapia Molecolare e Farmacogenomica, AZ. Istituti Ospitalieri di Cremona, Cremona, Italy (DG, AR, MRC, LD, ABo); Departments of Radiation Oncology (TB) and Pathology (FS), University of Texas MD Anderson Cancer Center, Houston, TX; Department of Medical Oncology and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (MC); Division of Experimental Therapeutics, Breast Cancer Program, Istituto Europeo di Oncologia, Milan, Italy (GC); Biomarkers Unit, Department of Experimental Oncology and Molecular Medicine (MGD), and Medical Oncology Unit (SDC), Fondazione IRCCS - Istituto Nazionale Tumori, Milan, Italy (MGD); Academic Department of Biochemistry, Biochemical Endocrinology (MD), Department of Surgery, Breast Unit (PB), and The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research and Breast Unit (MD, GS), Royal Marsden Hospital, London, UK; Department of Pathology, Melbourne University, Parkville, Australia (SF); Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK (ALH); Mount Vernon Cancer Centre, London, UK (AM); Section of Medical Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT (CH); Memorial Sloan Kettering Cancer Center, New York, NY (CAH); Division of Medical Oncology, Department of Hemato-oncology, IRCCS Policlinico 'San Matteo' Foundation, Pavia, Italy (PP); Dipartimento Medicina di Laboratorio, SC Anatomia ed Istocitopatologia Diagnostica e di Screening, A.O.U. Città della Salute e della Scienza di Torino, Università di Torino, Turin, Italy (AS); N. N. Petrov Research Institute of Oncology, St. Petersburg, Russia (VS); German Breast Group & University of Frankfurt, Neu-Isenburg, Germany (GvM); The Russell H. Morgan Department of Radiology

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http://dx.doi.org/10.1093/jncimonographs/lgv023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009414PMC
May 2015