Daniela Rossi

Daniela Rossi

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Daniela Rossi

Publications by authors named "Daniela Rossi"

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Reelin reverts biochemical, physiological and cognitive alterations in mouse models of Tauopathy.

Prog Neurobiol 2020 Mar 20;186:101743. Epub 2019 Dec 20.

Vall d'Hebron Institut de Recerca, 08035, Barcelona, Spain; Department of Cell Biology, Physiology and Immunology, and Institute of Neurosciences, University of Barcelona, 08028, Barcelona, Spain; Centro de Investigación en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 28031, Madrid, Spain; ICREA Academia, 08010, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2019.101743DOI Listing
March 2020

A novel homozygous mutation in the TRDN gene causes a severe form of pediatric malignant ventricular arrhythmia.

Heart Rhythm 2020 Feb 19;17(2):296-304. Epub 2019 Aug 19.

Vita-Salute San Raffaele University, Milan, Italy; Genomic Unit for the Diagnosis of Human Pathologies, Division of Genetics and Cellular Biology, IRCCS San Raffaele Hospital, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2019.08.018DOI Listing
February 2020

Thermography in systemic sclerosis patients and other rheumatic diseases: Diagnosis, disease activity assessment, and therapeutic monitoring.

Autoimmun Rev 2020 Feb 12;19(2):102449. Epub 2019 Dec 12.

Center of Research of Immunopathology and Rare Diseases, Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, SCDU Nephrology and Dialysis, S. Giovanni Bosco Hospital, Turin, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2019.102449DOI Listing
February 2020

Anti-beta-2-glycoprotein I domain 1 identifies antiphospholipid antibodies-related injuries in patients with concomitant lupus nephritis.

J Nephrol 2020 Jan 23. Epub 2020 Jan 23.

Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, SCDU Nephrology and Dialysis, S. Giovanni Bosco Hospital, Piazza del Donatore di Sangue 3, 10154, Turin, Italy.

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http://dx.doi.org/10.1007/s40620-019-00698-9DOI Listing
January 2020

New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative.

J Chem Inf Model 2019 Dec 20. Epub 2019 Dec 20.

Center for Bioinformatics and Molecular Simulation , Universidad de Talca , 1 Poniente , 1141 Talca , Chile.

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http://dx.doi.org/10.1021/acs.jcim.9b00649DOI Listing
December 2019

Identifying phenotypes of patients with antiphospholipid antibodies: results from a cluster analysis in a large cohort of patients.

Rheumatology (Oxford) 2019 Dec 16. Epub 2019 Dec 16.

Center of Research of Immunopathology and Rare Diseases/Nephrology and Dialysis Unit, Department of Clinical and Biological Sciences, S. Giovanni Bosco Hospital, Turin, Italy.

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http://dx.doi.org/10.1093/rheumatology/kez596DOI Listing
December 2019

Astrocytes in Motor Neuron Diseases.

Adv Exp Med Biol 2019 ;1175:227-272

Laboratory for Research on Neurodegenerative Disorders, IRCCS Istituti Clinici Scientifici Maugeri, Via Maugeri 4, 27100, Pavia, Italy.

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http://dx.doi.org/10.1007/978-981-13-9913-8_10DOI Listing
October 2019

Astrocytes: Emerging Therapeutic Targets in Neurological Disorders.

Trends Mol Med 2019 Sep 20;25(9):750-759. Epub 2019 May 20.

Laboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri - IRCCS, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2019.04.010DOI Listing
September 2019

Peptides in clinical development for the treatment of brain tumors.

Curr Opin Pharmacol 2019 Aug 5;47:102-109. Epub 2019 Apr 5.

Laboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri SpA SB - IRCCS, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2019.02.007DOI Listing
August 2019

Molecular determinants of homo- and heteromeric interactions of Junctophilin-1 at triads in adult skeletal muscle fibers.

Proc Natl Acad Sci U S A 2019 Jul 17;116(31):15716-15724. Epub 2019 Jul 17.

Department of Molecular and Developmental Medicine, Molecular Medicine Section, University of Siena, 53100 Siena, Italy;

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http://dx.doi.org/10.1073/pnas.1820980116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681751PMC
July 2019

Nailfold Capillaroscopy Patterns.

Isr Med Assoc J 2019 Jul;21(7):497-498

Center of Research of Immunopathology and Rare Diseases (CMID) - Division of Nephrology and Dialysis (ERK-net member), St. Giovanni Bosco Hospital and University of Turin, Turin, Italy.

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July 2019

DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents.

Molecules 2019 Mar 22;24(6). Epub 2019 Mar 22.

Drug Sciences Department, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.3390/molecules24061140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471984PMC
March 2019

Anticardiolipin and anti-beta 2 glycoprotein-I antibodies disappearance in patients with systemic lupus erythematosus and antiphospholipid syndrome while on belimumab.

Ann Rheum Dis 2018 11 18;77(11):1694-1695. Epub 2018 May 18.

Center of Research of Immunopathology and Rare Diseases-Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, S. Giovanni Bosco Hospital, University of Turin, Turin, Italy.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2018-21349
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http://dx.doi.org/10.1136/annrheumdis-2018-213496DOI Listing
November 2018

Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.

Eur J Med Chem 2018 Oct 8;158:353-370. Epub 2018 Sep 8.

Department of Drug Sciences, Medicinal Chemistry, Pharmaceutical Technology and Pharmacological Sections, University of Pavia, Viale Taramelli 6 and 12, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.09.010DOI Listing
October 2018

Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis.

Front Neurosci 2018 29;12:622. Epub 2018 Aug 29.

Laboratory for Research on Neurodegenerative Disorders, IRCCS Istituti Clinici Scientifici Maugeri (ICS Maugeri), Pavia, Italy.

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http://dx.doi.org/10.3389/fnins.2018.00622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123379PMC
August 2018

High-Dose Rituximab Ineffective for Focal Segmental Glomerulosclerosis: A Long-Term Observation Study.

Am J Nephrol 2017 13;46(2):108-113. Epub 2017 Jul 13.

Center of Research of Immunopathology and Rare Diseases - Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1159/000477944DOI Listing
May 2018

CSF neurofilament proteins as diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis.

J Neurol 2018 Mar 10;265(3):510-521. Epub 2018 Jan 10.

Department of Experimental BioMedicine and Clinical Neurosciences, ALS Clinical Research Center, University of Palermo, Via G La Loggia, 1, 90129, Palermo, Italy.

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http://dx.doi.org/10.1007/s00415-017-8730-6DOI Listing
March 2018

Improved (4 Plus 2) Rituximab Protocol for Severe Cases of Mixed Cryoglobulinemia: A 6-Year Observational Study.

Am J Nephrol 2016 29;43(4):251-60. Epub 2016 Apr 29.

Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, S. Giovanni Bosco Hospital, Turin, Italy.

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http://dx.doi.org/10.1159/000445841DOI Listing
January 2018

Approaches for multi-gram scale isolation of enantiomers for drug discovery.

Expert Opin Drug Discov 2017 12 3;12(12):1253-1269. Epub 2017 Oct 3.

a Drug Sciences Department, Medicinal Chemistry and Pharmaceutical Technology Section , University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/17460441.2017.1383981DOI Listing
December 2017

Are sigma receptor modulators a weapon against multiple sclerosis disease?

Future Med Chem 2017 11 27;9(17):2029-2051. Epub 2017 Oct 27.

Experimental Neurology Unit, Department of Medicine & Surgery & Milan Center for Neuroscience, University of Milan Bicocca, Via Cadore 48, Monza 20900, Italy.

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http://dx.doi.org/10.4155/fmc-2017-0122DOI Listing
November 2017

Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs.

J Med Chem 2017 10 19;60(20):8257-8267. Epub 2017 Jun 19.

Department of Drug Sciences, Medicinal Chemistry and Technology Section, University of Pavia , Via Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.6b01871DOI Listing
October 2017

How I treat patients with systemic sclerosis in clinical practice.

Autoimmun Rev 2017 Oct 1;16(10):1024-1028. Epub 2017 Aug 1.

Rheumatology Unit, University Hospital, Padua, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2017.07.018DOI Listing
October 2017

How I treat patients with adult onset Still's disease in clinical practice.

Autoimmun Rev 2017 Oct 1;16(10):1016-1023. Epub 2017 Aug 1.

Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, S. Giovanni Bosco Hospital and University of Turin, Turin, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2017.07.017DOI Listing
October 2017

The role of chirality in a set of key intermediates of pharmaceutical interest, 3-aryl-substituted-γ-butyrolactones, evidenced by chiral HPLC separation and by chiroptical spectroscopies.

J Pharm Biomed Anal 2017 Sep 5;144:41-51. Epub 2017 Jan 5.

Dipartimento di Medicina Molecolare e Traslazionale, Università di Brescia, Viale Europa 11, 25123 Brescia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2017.01.007DOI Listing
September 2017

The potential of obscurin as a therapeutic target in muscle disorders.

Expert Opin Ther Targets 2017 09 4;21(9):897-910. Epub 2017 Aug 4.

b Molecular Medicine Section, Department of Molecular and Developmental Medicine , University of Siena , Siena , Italy.

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http://dx.doi.org/10.1080/14728222.2017.1361931DOI Listing
September 2017

The "4 plus 2" rituximab protocol makes maintenance treatment unneeded in patients with refractory ANCA-associated vasculitis: A 10 years observation study.

Oncotarget 2017 Aug 23;8(32):52072-52077. Epub 2017 May 23.

Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.

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http://www.oncotarget.com/fulltext/18120
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http://dx.doi.org/10.18632/oncotarget.18120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581013PMC
August 2017

The challenge of treating hepatitis C virus-associated cryoglobulinemic vasculitis in the era of anti-CD20 monoclonal antibodies and direct antiviral agents.

Oncotarget 2017 Jun;8(25):41764-41777

Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, S. Giovanni Bosco Hospital and University of Turin, Turin, Italy.

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http://dx.doi.org/10.18632/oncotarget.16986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522247PMC
June 2017

Outpatient percutaneous native renal biopsy: safety profile in a large monocentric cohort.

BMJ Open 2017 06 21;7(6):e015243. Epub 2017 Jun 21.

Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases-Coordinating Center of the Network for Rare Diseases of Piedmont and Aosta Valley, University of Turin, San Giovanni Hospital, Turin, Italy.

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http://dx.doi.org/10.1136/bmjopen-2016-015243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734246PMC
June 2017

Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016).

Expert Opin Ther Pat 2017 May 13;27(5):565-578. Epub 2017 Jan 13.

d MBiochem, Biosciences Laboratory , Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), IRCCS , Meldola , Italy.

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https://www.tandfonline.com/doi/full/10.1080/13543776.2017.1
Publisher Site
http://dx.doi.org/10.1080/13543776.2017.1276569DOI Listing
May 2017

PKC in Regenerative Therapy: New Insights for Old Targets.

Pharmaceuticals (Basel) 2017 May 18;10(2). Epub 2017 May 18.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.3390/ph10020046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490403PMC
May 2017

Cell-Penetrating Peptides: From Basic Research to Clinics.

Trends Pharmacol Sci 2017 04 14;38(4):406-424. Epub 2017 Feb 14.

Laboratory for Research on Neurodegenerative Disorders, IRCCS Maugeri Clinical and Scientific Institutes SpA SB, Via Maugeri 10, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2017.01.003DOI Listing
April 2017

Early impairment of somatosensory evoked potentials in very young children with achondroplasia with foramen magnum stenosis.

Dev Med Child Neurol 2017 Feb 16;59(2):192-198. Epub 2016 Sep 16.

Head-Neck and Neuroscience Department, Child Neuropsychiatry Unit, Istituto Giannina Gaslini, Genova, Italy.

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http://dx.doi.org/10.1111/dmcn.13243DOI Listing
February 2017

Enantioselective Modulatory Effects of Naringenin  Enantiomers on the Expression Levels of miR-17-3p  Involved in Endogenous Antioxidant Defenses.

Nutrients 2017 Feb 28;9(3). Epub 2017 Feb 28.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, Pavia University, Viale Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.3390/nu9030215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372878PMC
February 2017

Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines.

Bioorg Med Chem 2017 01 11;25(1):11-19. Epub 2016 Oct 11.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.10.005DOI Listing
January 2017

Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents.

Eur J Med Chem 2016 Nov 31;124:649-665. Epub 2016 Aug 31.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 6 and 12, 27100, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.08.067DOI Listing
November 2016

Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment.

Molecules 2016 Sep 10;21(9). Epub 2016 Sep 10.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 12, Pavia 27100, Italy.

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http://dx.doi.org/10.3390/molecules21091210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273946PMC
September 2016

Disruption of the astrocytic TNFR1-GDNF axis accelerates motor neuron degeneration and disease progression in amyotrophic lateral sclerosis.

Hum Mol Genet 2016 07 10;25(14):3080-3095. Epub 2016 Jun 10.

Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, 27100 Pavia, Italy,

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http://dx.doi.org/10.1093/hmg/ddw161DOI Listing
July 2016

Withaferin A Inhibits Nuclear Factor-κB-Dependent Pro-Inflammatory and Stress Response Pathways in the Astrocytes.

Neural Plast 2015 21;2015:381964. Epub 2015 Jul 21.

Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, 27100 Pavia, Italy.

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http://dx.doi.org/10.1155/2015/381964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523683PMC
April 2016

Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists.

Biomed Chromatogr 2016 Apr 8;30(4):645-51. Epub 2015 Oct 8.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology section, University of Pavia, Viale Taramelli 12, 27100, Pavia, Italy.

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http://dx.doi.org/10.1002/bmc.3609DOI Listing
April 2016

"Fit-for-purpose" development of analytical and (semi)preparative enantioselective high performance liquid and supercritical fluid chromatography for the access to a novel σ1 receptor agonist.

J Pharm Biomed Anal 2016 Jan 4;118:363-369. Epub 2015 Nov 4.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2015.10.047DOI Listing
January 2016

A 4-year observation in lupus nephritis patients treated with an intensified B-lymphocyte depletion without immunosuppressive maintenance treatment-Clinical response compared to literature and immunological re-assessment.

Autoimmun Rev 2015 Dec 2;14(12):1123-30. Epub 2015 Aug 2.

Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Center of Research of Immunopathology and Rare Diseases-Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, Turin, Italy.

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http://dx.doi.org/10.1016/j.autrev.2015.07.017DOI Listing
December 2015

Organization of junctional sarcoplasmic reticulum proteins in skeletal muscle fibers.

J Muscle Res Cell Motil 2015 Dec 15;36(6):501-15. Epub 2015 Sep 15.

Molecular Medicine Section, Department of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro 2, 53100, Siena, Italy.

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http://dx.doi.org/10.1007/s10974-015-9421-5DOI Listing
December 2015

Rheumatoid arthritis: Biological therapy other than anti-TNF.

Int Immunopharmacol 2015 Aug 31;27(2):185-8. Epub 2015 Mar 31.

Center of Research of Immunopathology and Rare Diseases (CMID), Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Giovanni Bosco Hospital, Turin, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2015.03.019DOI Listing
August 2015

Somatic signature of brain-specific single nucleotide variations in sporadic Alzheimer's disease.

J Alzheimers Dis 2014 ;42(4):1357-82

Department of Cell Biology, University of Barcelona, Barcelona, Spain Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED, ISCIII), Spain Fundación CIEN, Vallecas, Madrid, Spain Vall d'Hebrón Institut de Recerca (VHIR), Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-140891DOI Listing
July 2015

Astrocyte physiopathology: At the crossroads of intercellular networking, inflammation and cell death.

Authors:
Daniela Rossi

Prog Neurobiol 2015 Jul 27;130:86-120. Epub 2015 Apr 27.

Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, Via Maugeri 10, 27100 Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2015.04.003DOI Listing
July 2015

Yip1B isoform is localized at ER-Golgi intermediate and cis-Golgi compartments and is not required for maintenance of the Golgi structure in skeletal muscle.

Histochem Cell Biol 2015 Mar 11;143(3):235-43. Epub 2014 Sep 11.

Department of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro, Siena, Italy.

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http://dx.doi.org/10.1007/s00418-014-1277-zDOI Listing
March 2015

Hydrogen/deuterium exchange-protected oligomers populated during Aβ fibril formation correlate with neuronal cell death.

ACS Chem Biol 2014 Nov 29;9(11):2678-85. Epub 2014 Sep 29.

Institute for Research in Biomedicine (IRB Barcelona), Baldiri Reixac 10, Barcelona 08028, Spain.

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http://dx.doi.org/10.1021/cb500621xDOI Listing
November 2014

A mutation in the CASQ1 gene causes a vacuolar myopathy with accumulation of sarcoplasmic reticulum protein aggregates.

Hum Mutat 2014 Oct 10;35(10):1163-70. Epub 2014 Sep 10.

Molecular Medicine Section, Department of Molecular and Developmental Medicine, University of Siena and Azienda Ospedaliera Universitaria Senese, Siena, 53100, Italy; IIM, Interuniversity Institute of Myology.

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http://dx.doi.org/10.1002/humu.22631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177304PMC
October 2014

TNF-α blocker effect of naringenin-loaded sericin microparticles that are potentially useful in the treatment of psoriasis.

Int J Mol Sci 2014 Aug 6;15(8):13624-36. Epub 2014 Aug 6.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section (MCPTS), Medicinal Chemistry Laboratory, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.3390/ijms150813624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159815PMC
August 2014

Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer's disease.

Nat Commun 2014 Mar 6;5:3443. Epub 2014 Mar 6.

1] Department of Cell Biology, University of Barcelona, Barcelona 08028, Spain [2] Centro de Investigación en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid 28031, Spain [3] Institute for Research in Biomedicine, Barcelona (IRB Barcelona), Barcelona 08028, Spain [4] Vall D'Hebrón Institut de Recerca (VHIR), Barcelona 08035, Spain [5] CIEN Foundation, Madrid 28031, Spain.

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http://dx.doi.org/10.1038/ncomms4443DOI Listing
March 2014

Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.

Neurobiol Dis 2014 Feb 16;62:218-32. Epub 2013 Oct 16.

Department of Biology and Biotechnology "L. Spallanzani", Laboratory of Cellular & Molecular Neuropharmacology, University of Pavia, Pavia, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09699961130028
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http://dx.doi.org/10.1016/j.nbd.2013.10.010DOI Listing
February 2014

The multifaceted role of glial cells in amyotrophic lateral sclerosis.

Cell Mol Life Sci 2014 Jan 3;71(2):287-97. Epub 2013 Aug 3.

Department of Neuropathology, German Center for Neurodegenerative Diseases (DZNE), Paul-Ehrlich-Strasse 17, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00018-013-1429-7DOI Listing
January 2014

Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.

Chirality 2013 Nov 7;25(11):814-22. Epub 2013 Sep 7.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology section, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1002/chir.22223DOI Listing
November 2013

Astrocyte signaling and neurodegeneration: new insights into CNS disorders.

Prion 2013 Jan-Feb;7(1):28-36. Epub 2012 Oct 23.

Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy.

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http://dx.doi.org/10.4161/pri.22512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609047PMC
August 2013

An eco-friendly enantioselective access to (R)-naringenin as inhibitor of proinflammatory cytokine release.

Chem Biodivers 2013 Aug;10(8):1531-8

Department of Drug Sciences, University of Pavia, Viale Taramelli 12, I-27100 Pavia, Italy.

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http://dx.doi.org/10.1002/cbdv.201200227DOI Listing
August 2013

The role of nail-videocapillaroscopy in early diagnosis of scleroderma.

Autoimmun Rev 2013 Jun 4;12(8):821-5. Epub 2012 Dec 4.

Department of Rare, Immunologic, Hematologic Diseases and Transfusion Medicine, Research Center of Immunopathology and Rare Diseases (CMID), Giovanni Bosco Hospital and University of Turin, Italy.

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http://dx.doi.org/10.1016/j.autrev.2012.11.006DOI Listing
June 2013

Identification of peptides with ELAV-like mRNA-stabilizing effect: an integrated in vitro/in silico approach.

Chem Biol Drug Des 2013 Jun 11;81(6):707-14. Epub 2013 Apr 11.

Pharmacology Section, Department of Drug Sciences, University of Pavia, Viale Taramelli 12, Pavia 27100, Italy.

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http://dx.doi.org/10.1111/cbdd.12117DOI Listing
June 2013

Sigma receptor modulators: a patent review.

Expert Opin Ther Pat 2013 May 7;23(5):597-613. Epub 2013 Feb 7.

University of Pavia, Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, Pavia, Italy.

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http://dx.doi.org/10.1517/13543776.2013.769522DOI Listing
May 2013

The peroxisome proliferator-activated receptor γ (PPARγ) controls natural protective mechanisms against lipid peroxidation in amyotrophic lateral sclerosis.

J Biol Chem 2012 Oct 21;287(43):35899-911. Epub 2012 Aug 21.

Center of Excellence on Neurodegenerative Diseases and Department of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.

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http://dx.doi.org/10.1074/jbc.M112.366419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476258PMC
October 2012

Long-term effects of methylprednisolone pulses and mycophenolate mofetil in IgA nephropathy patients at risk of progression.

J Nephrol 2012 Mar-Apr;25(2):198-203

Center for Immunopathology and Rare Diseases, Department of Rare, Immunologic, Haematologic and Immunohaematologic Diseases, San G. Bosco Hospital and University of Turin, Turin, Italy.

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http://dx.doi.org/10.5301/JN.2011.8452DOI Listing
August 2012

8-isoprostane, prostaglandin E2, C-reactive protein and serum amyloid A as markers of inflammation and oxidative stress in antiphospholipid syndrome: a pilot study.

Inflamm Res 2012 Aug 26;61(8):809-16. Epub 2012 May 26.

Dipartimento di Malattie Rare, Immunologiche, Ematologiche ed Immunoematologiche, Ospedale Torino Nord Emergenza San G. Bosco ed Università di Torino, Turin, Italy.

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http://dx.doi.org/10.1007/s00011-012-0468-0DOI Listing
August 2012

Early-onset neurodegeneration with brain iron accumulation due to PANK2 mutation.

Brain Dev 2012 Jun 14;34(6):536-8. Epub 2011 Oct 14.

Child Neurology and Psychiatry Unit, G. Gaslini Institute, Genova, Italy.

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http://dx.doi.org/10.1016/j.braindev.2011.09.010DOI Listing
June 2012

Mycophenolate mofetil as steroid-sparing treatment for elderly patients with giant cell arteritis: report of three cases.

Aging Clin Exp Res 2012 Jun;24(3):273-7

Dipartimento di Malattie Rare, Immunologiche, Ematologiche ed Immunopatologiche, Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale Torino Nord, Emergenza San G. Bosco ed Università di Torino, Italy.

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http://dx.doi.org/10.1007/bf03325257DOI Listing
June 2012

The BH4 domain of Bcl-X(L) rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals.

Hum Mol Genet 2012 Feb 9;21(4):826-40. Epub 2011 Nov 9.

Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, 27100 Pavia, Italy.

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http://dx.doi.org/10.1093/hmg/ddr513DOI Listing
February 2012

Long-term effects of rituximab added to cyclophosphamide in refractory patients with vasculitis.

Am J Nephrol 2011 8;34(2):175-80. Epub 2011 Jul 8.

Dipartimento di Malattie Rare, Immunologiche, Ematologiche ed Immunoematologiche, Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare (CMID), Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Ospedale Torino Nord Emergenza San G. Bosco ed Università di Torino, Italia. dario.roccatello @ unito.it

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http://dx.doi.org/10.1159/000329535DOI Listing
January 2012

Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.

Neuropsychopharmacology 2011 Nov 3;36(12):2395-405. Epub 2011 Aug 3.

Developmental Neurobiology and Regeneration Unit, Institute for Research in Biomedicine, Parc Cientific de Barcelona, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1038/npp.2011.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194085PMC
November 2011

Binding studies and quantitative structure-activity relationship of 3-amino-1H-indazoles as inhibitors of GSK3β.

Chem Biol Drug Des 2011 Oct 25;78(4):631-41. Epub 2011 Aug 25.

Centro de Bioinformática y Simulación Molecular, Facultad de Ingeniería en Bioinformática, Universidad de Talca, 2 Norte 685, Casilla 721, Talca, Chile.

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http://dx.doi.org/10.1111/j.1747-0285.2011.01186.xDOI Listing
October 2011

Implications of gliotransmission for the pharmacotherapy of CNS disorders.

CNS Drugs 2011 Aug;25(8):641-58

Laboratory for Research on Neurodegenerative Disorders, IRCCS Fondazione Salvatore Maugeri, Pavia, Italy.

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http://dx.doi.org/10.2165/11593090-000000000-00000DOI Listing
August 2011