Daniel Ziemek

Daniel Ziemek

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Daniel Ziemek

Daniel Ziemek

Publications by authors named "Daniel Ziemek"

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SUBSTRA: Supervised Bayesian Patient Stratification.

Bioinformatics 2019 Sep;35(18):3263-3272

Computational Systems Immunology, Pfizer Worldwide R&D, Berlin, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btz112DOI Listing
September 2019

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci.

Nucleic Acids Res 2019 01;47(1):e3

MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1093/nar/gky837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326795PMC
January 2019

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.

Diabetes 2018 07 27;67(7):1414-1427. Epub 2018 Apr 27.

Wellcome Centre Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.

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http://dx.doi.org/10.2337/db17-0914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014557PMC
July 2018

From the Cover: Fenretinide, Troglitazone, and Elmiron Add to Weight of Evidence Support for Hemangiosarcoma Mode-of-Action From Studies in Mice.

Toxicol Sci 2018 01;161(1):58-75

Pfizer Worldwide Research and Development, Pfizer, Drug Safety Research and Development, Groton, Connecticut 06340.

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http://dx.doi.org/10.1093/toxsci/kfx195DOI Listing
January 2018

Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes.

Sci Rep 2018 01 19;8(1):1237. Epub 2018 Jan 19.

Computational Sciences, Pfizer Worldwide Research & Development, Cambridge, MA, 02139, USA.

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http://dx.doi.org/10.1038/s41598-018-19635-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775343PMC
January 2018

A biological network-based regularized artificial neural network model for robust phenotype prediction from gene expression data.

BMC Bioinformatics 2017 Dec 19;18(1):565. Epub 2017 Dec 19.

Department of Mathematics, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, 0212, MA, USA.

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http://dx.doi.org/10.1186/s12859-017-1984-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735940PMC
December 2017

Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks.

BMC Bioinformatics 2016 Aug 24;17(1):318. Epub 2016 Aug 24.

Department of Mathematics, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, 02125, USA.

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http://dx.doi.org/10.1186/s12859-016-1181-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995651PMC
August 2016

Robust clinical outcome prediction based on Bayesian analysis of transcriptional profiles and prior causal networks.

Bioinformatics 2014 Jun;30(12):i69-77

Computational Sciences Center of Emphasis, Pfizer Worldwide R&D, Cambridge, Department of Mathematics, University of Massachusetts Boston, Boston, MA, Drug Safety Research & Development, Pfizer Worldwide R&D, Groton, CT, USA and Computational Sciences Center of Emphasis, Pfizer Worldwide R&D, Berlin, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btu272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058945PMC
June 2014

Molecular causes of transcriptional response: a Bayesian prior knowledge approach.

Bioinformatics 2013 Dec 26;29(24):3167-73. Epub 2013 Sep 26.

Computational Sciences Center of Emphasis, Pfizer Worldwide Research & Development, Cambridge, MA 02140, USA, Department of Mathematics, University of Massachusetts Boston, Boston, MA 02125, USA, Drug Safety Research & Development, Pfizer, Groton, CT 06340, USA and Neusentis, Pfizer Worldwide Research & Development, Cambridge CB21 6GS, UK.

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http://dx.doi.org/10.1093/bioinformatics/btt557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994944PMC
December 2013

Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression.

J Lipid Res 2012 Aug 23;53(8):1459-71. Epub 2012 May 23.

Department of Cardiovascular, Metabolic, and Endocrine Diseases, Pfizer Inc., Cambridge, MA, USA.

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http://dx.doi.org/10.1194/jlr.M020941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540863PMC
August 2012

Causal reasoning on biological networks: interpreting transcriptional changes.

Bioinformatics 2012 Apr 21;28(8):1114-21. Epub 2012 Feb 21.

Computational Sciences Center of Emphasis, Pfizer Worldwide Research & Development, Cambridge, MA 02140, USA.

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http://dx.doi.org/10.1093/bioinformatics/bts090DOI Listing
April 2012

Correlation set analysis: detecting active regulators in disease populations using prior causal knowledge.

BMC Bioinformatics 2012 Mar 23;13:46. Epub 2012 Mar 23.

Bioinformatics Graduate Program, and Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-13-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382432PMC
March 2012

Assessing statistical significance in causal graphs.

BMC Bioinformatics 2012 Feb 20;13:35. Epub 2012 Feb 20.

Computational Sciences Center of Emphasis, Pfizer Worldwide Research & Development, Cambridge, MA, USA.

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http://dx.doi.org/10.1186/1471-2105-13-35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307026PMC
February 2012

Characterization of human cardiac Kv1.5 inhibition by the novel atrial-selective antiarrhythmic compound AVE1231.

J Cardiovasc Pharmacol 2008 Apr;51(4):380-7

Division of Cardiology, J.W. Goethe-Universität, Frankfurt, Germany.

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http://dx.doi.org/10.1097/FJC.0b013e3181669030DOI Listing
April 2008