Publications by authors named "Daniel Schramek"

41Publications

CRISPR screens reveal potent driver mutations in head and neck cancers.

Mol Cell Oncol 2020 13;7(4):1758541. Epub 2020 May 13.

Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1080/23723556.2020.1758541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469622PMC
May 2020

Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins.

Cell 2020 Jul 25;182(2):345-356.e16. Epub 2020 Jun 25.

Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Molecular Architecture of Life Program, Canadian Institute for Advanced Research (CIFAR), Toronto, ON M5G 1M1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316060PMC
July 2020

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.

Cell 2020 Jun 22;181(6):1329-1345.e24. Epub 2020 May 22.

The Arthur and Sonia Labatt Brain Tumor Research Center, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.04.047DOI Listing
June 2020

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling.

Science 2020 03;367(6483):1264-1269

Centre for Molecular and Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1126/science.aax0902DOI Listing
March 2020

CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.

Nat Commun 2019 11 29;10(1):5454. Epub 2019 Nov 29.

Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Dr. Bohr Gasse 3, 1030, Vienna, Austria.

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http://dx.doi.org/10.1038/s41467-019-13403-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884486PMC
November 2019

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.

Nat Methods 2017 Dec 16;14(12):1191-1197. Epub 2017 Oct 16.

Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna Biocenter (VBC), Vienna, Austria.

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http://dx.doi.org/10.1038/nmeth.4466DOI Listing
December 2017

Translation from unconventional 5' start sites drives tumour initiation.

Nature 2017 01 11;541(7638):494-499. Epub 2017 Jan 11.

Robin Chemers Neustein Laboratory of Mammalian Development and Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nature21036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287289PMC
January 2017

ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas.

Elife 2015 Nov 21;4:e10870. Epub 2015 Nov 21.

Howard Hughes Medical Institute, Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, United States.

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http://dx.doi.org/10.7554/eLife.10870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739765PMC
November 2015

MKK7 and ARF: new players in the DNA damage response scenery.

Cell Cycle 2014 26;13(8):1227-36. Epub 2014 Mar 26.

Molecular Carcinogenesis Group; Department of Histology and Embryology; School of Medicine; University of Athens; Athens, Greece; Faculty Institute of Cancer Sciences; University of Manchester; Manchester Academic Health Science Centre; Manchester, UK; Manchester Centre for Cellular Metabolism; University of Manchester; Manchester Academic Health Science Centre; Manchester, UK; Biomedical Research Foundation; Academy of Athens; Athens, Greece.

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http://dx.doi.org/10.4161/cc.28654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049959PMC
August 2015

Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas.

Science 2014 Jan;343(6168):309-13

Howard Hughes Medical Institute, Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1126/science.1248627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159249PMC
January 2014

Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells.

Development 2013 Apr 5;140(7):1397-401. Epub 2013 Mar 5.

Cancer Research Program, Garvan Institute of Medical Research, 348 Victoria Street, and St Vincent's Hospital Clinical School, University of New South Wales, Darlinghurst NSW 2010, Australia.

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http://dev.biologists.org/cgi/doi/10.1242/dev.088948
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http://dx.doi.org/10.1242/dev.088948DOI Listing
April 2013

RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis.

Trends Endocrinol Metab 2011 May 4;22(5):188-94. Epub 2011 Apr 4.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohr Gasse 3, 1030 Vienna, Austria.

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http://dx.doi.org/10.1016/j.tem.2011.02.007DOI Listing
May 2011

RANKL/RANK-beyond bones.

J Mol Med (Berl) 2011 Jul 29;89(7):647-56. Epub 2011 Mar 29.

IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1007/s00109-011-0749-zDOI Listing
July 2011

Respiratory inductive plethysmography as a method for measuring ventilatory parameters in conscious, non-restrained dogs.

J Pharmacol Toxicol Methods 2010 Jul-Aug;62(1):47-53. Epub 2010 May 8.

Department of Safety Pharmacology, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.vascn.2010.04.006DOI Listing
December 2010

Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein.

J Biol Chem 2006 Jan 27;281(1):626-37. Epub 2005 Oct 27.

Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1074/jbc.M509567200DOI Listing
January 2006

Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor.

Cancer Res 2005 Apr;65(8):3273-80

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2118DOI Listing
April 2005