Daniel S Ory

Daniel S Ory

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Daniel S Ory

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Binding and intracellular transport of 25-hydroxycholesterol by Niemann-Pick C2 protein.

Biochim Biophys Acta Biomembr 2019 Sep 12:183063. Epub 2019 Sep 12.

Department of Biochemistry and Molecular Biology, DK-5230 Odense M, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.183063DOI Listing
September 2019

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness.

Diabetol Metab Syndr 2019 29;11:61. Epub 2019 Jul 29.

1Division of Endocrinology, Metabolism & Lipid Research, Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Box 8127, St. Louis, MO 63110 USA.

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http://dx.doi.org/10.1186/s13098-019-0456-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664523PMC
July 2019

Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P That Regulates Neuronal Excitability.

Cell Rep 2019 May;27(9):2636-2648.e4

Department of Physiology and Membrane Biology, University of California, Davis, Davis, CA 95616, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.04.099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553496PMC
May 2019

Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders.

Free Radic Biol Med 2019 Apr 19. Epub 2019 Apr 19.

Institute of Life Science, Swansea University Medical School, Singleton Park, Swansea, SA2 8PP, UK. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.04.020DOI Listing
April 2019

Diagnosis of niemann-pick C1 by measurement of bile acid biomarkers in archived newborn dried blood spots.

Mol Genet Metab 2019 02 24;126(2):183-187. Epub 2018 Aug 24.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2018.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365165PMC
February 2019

Comprehensive behavioral and biochemical outcomes of novel murine models of GM1-gangliosidosis and Morquio syndrome type B.

Mol Genet Metab 2019 02 22;126(2):139-150. Epub 2018 Nov 22.

Gene Therapy Center, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States; Molecular, Cellular, Developmental Biology, and Genetics Graduate Program, University of Minnesota, Minneapolis, MN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2018.11.002DOI Listing
February 2019

Impaired monocyte cholesterol clearance initiates age-related retinal degeneration and vision loss.

JCI Insight 2018 Sep 6;3(17). Epub 2018 Sep 6.

Department of Ophthalmology and Visual Sciences, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1172/jci.insight.120824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171801PMC
September 2018

Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.

J Lipid Res 2018 08 26;59(8):1414-1423. Epub 2018 Jun 26.

Departments of Ophthalmology and Visual Sciences Washington University School of Medicine in St. Louis, St. Louis, MO 63110

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http://dx.doi.org/10.1194/jlr.M084442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770PMC
August 2018

19q13.12 microdeletion syndrome fibroblasts display abnormal storage of cholesterol and sphingolipids in the endo-lysosomal system.

Biochim Biophys Acta Mol Basis Dis 2018 06 24;1864(6 Pt A):2108-2118. Epub 2018 Mar 24.

Atlantic Research Center, Depts. of Pediatrics and Biochemistry & Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394866PMC
June 2018

High-content screen for modifiers of Niemann-Pick type C disease in patient cells.

Hum Mol Genet 2018 06;27(12):2101-2112

Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1093/hmg/ddy117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985738PMC
June 2018

Oxysterol Signatures Distinguish Age-Related Macular Degeneration from Physiologic Aging.

EBioMedicine 2018 Jun 11;32:9-20. Epub 2018 Jun 11.

Department of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA; Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021272PMC
June 2018

Structural design of intrinsically fluorescent oxysterols.

Chem Phys Lipids 2018 05 26;212:26-34. Epub 2017 Dec 26.

Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2017.12.005DOI Listing
May 2018

Author Correction: Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies.

Sci Rep 2018 Apr 18;8(1):6361. Epub 2018 Apr 18.

Center for Applied Research in Applied Biomedical Mass Spectrometry (ABIMAS), Mannheim University of Applied Sciences, Paul-Wittsack Str. 10, 68163, Mannheim, Germany.

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http://dx.doi.org/10.1038/s41598-018-24807-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906574PMC
April 2018

Long-Term Treatment of Niemann-Pick Type C1 Disease With Intrathecal 2-Hydroxypropyl-β-Cyclodextrin.

Pediatr Neurol 2018 03 8;80:24-34. Epub 2018 Jan 8.

Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois; Department of Cell and Molecular Medicine, Rush University Medical Center, Chicago, Illinois.

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http://dx.doi.org/10.1016/j.pediatrneurol.2017.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857219PMC
March 2018

Bariatric Surgery-Induced Cardiac and Lipidomic Changes in Obesity-Related Heart Failure with Preserved Ejection Fraction.

Obesity (Silver Spring) 2018 02 15;26(2):284-290. Epub 2017 Dec 15.

Cardiovascular Division, Department of Medicine, School of Medicine, Washington University, St Louis, Missouri, USA.

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http://dx.doi.org/10.1002/oby.22038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783730PMC
February 2018

Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies.

Sci Rep 2018 01 10;8(1):313. Epub 2018 Jan 10.

Center for Applied Research in Applied Biomedical Mass Spectrometry (ABIMAS), Mannheim University of Applied Sciences, Paul-Wittsack Str. 10, 68163, Mannheim, Germany.

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http://dx.doi.org/10.1038/s41598-017-18477-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762902PMC
January 2018

Nuclear export factor 3 regulates localization of small nucleolar RNAs.

J Biol Chem 2017 12 11;292(49):20228-20239. Epub 2017 Oct 11.

From the Diabetes Research Center, Department of Medicine, and

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http://dx.doi.org/10.1074/jbc.M117.818146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724009PMC
December 2017

Recommendations for the detection and diagnosis of Niemann-Pick disease type C: An update.

Neurol Clin Pract 2017 Dec;7(6):499-511

Mayo Clinic (MCP), Rochester, MN; UCL Great Ormond Street Institute of Child Health (PC, PG), London, UK; Great Ormond Street Hospital (PG), London, UK; Département de Neurologie (MA), Hôpital de Hautepierre, CHU de Strasbourg; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) (MA), INSERM-U964/CNRS-UMR7104/Université de Strasbourg, Illkirch; Fédération de Médecine Translationnelle de Strasbourg (FMTS) (MA), Université de Strasbourg, France; Institute of Medical Genetics and Applied Genomics (PB), University Hospital of Tübingen; Centogene AG (PB), Rostock, Germany; Universitaire de Psychiatrie de l'Enfant et de l'Adolescent (OB), CHU de Nantes, France; Regional Coordinator Centre for Rare Diseases (AD), University Hospital Santa Maria della Misericordia, Udine, Italy; Division of Metabolism, Bambino Gesù Children's Hospital (CD-V), Rome, Italy; Klinik und Poliklinik für Psychiatrie, Psychosomatik und Psychotherapie der Universität Regensburg am Bezirksklinikum (H-HK), Regensburg, Germany; Hospices Civils de Lyon-Centre de Biologie et Pathologie Est (PL), Bron, France; University of São Paulo (HCFMRP-USP) (CML), Ribeirão Preto, SP, Brazil; Department of Medicine (DSO), Washington University, St Louis, MO; Child Development Centre (AP), Addenbrooke's Hospital, Cambridge, UK; University of Zaragoza (MP), IIS Aragon, Spain; Department of Neurology and German Center for Vertigo and Balance Disorders (MS), University Hospital Munich, Germany; Laboratoire Gillet-Mérieux (MTV), Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Bron, France; Department of Neuropsychiatry (MW), Royal Melbourne Hospital & University of Melbourne, Australia; and Universitätsklinikum Münster (TM), Germany.

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http://dx.doi.org/10.1212/CPJ.0000000000000399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800709PMC
December 2017

Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy.

Mol Ther Methods Clin Dev 2017 Sep 26;6:135-142. Epub 2017 Jul 26.

Scott-Ritchey Research Center, Auburn University College of Veterinary Medicine, Auburn, AL 36849, USA.

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http://dx.doi.org/10.1016/j.omtm.2017.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545771PMC
September 2017

Fostering collaborative research for rare genetic disease: the example of niemann-pick type C disease.

Orphanet J Rare Dis 2016 12 1;11(1):161. Epub 2016 Dec 1.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine, Box 8086, 660 S. Euclid Ave, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1186/s13023-016-0540-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131440PMC
December 2016

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes.

Nature 2016 11 2;539(7628):294-298. Epub 2016 Nov 2.

Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/nature20117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671339PMC
November 2016

Establishing the precise evolutionary history of a gene improves prediction of disease-causing missense mutations.

Genet Med 2016 10 18;18(10):1029-36. Epub 2016 Feb 18.

Graduate School of Genome Science and Technology, University of Tennessee-Oak Ridge National Laboratory, Knoxville, Tennessee, USA.

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http://dx.doi.org/10.1038/gim.2015.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990510PMC
October 2016

Intrathecal 2-hydroxypropyl-beta-cyclodextrin in a single patient with Niemann-Pick C1.

Mol Genet Metab 2015 Sep-Oct;116(1-2):75-9. Epub 2015 Jul 15.

Department of Pediatrics, Division of Medical Genetics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.

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http://dx.doi.org/10.1016/j.ymgme.2015.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633280PMC
July 2016

Genetic and pharmacological evidence implicates cathepsins in Niemann-Pick C cerebellar degeneration.

Hum Mol Genet 2016 Apr 28;25(7):1434-46. Epub 2016 Jan 28.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA and

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http://dx.doi.org/10.1093/hmg/ddw025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787909PMC
April 2016

A Diet Rich in Medium-Chain Fatty Acids Improves Systolic Function and Alters the Lipidomic Profile in Patients With Type 2 Diabetes: A Pilot Study.

J Clin Endocrinol Metab 2016 Feb 10;101(2):504-12. Epub 2015 Dec 10.

Department of Medicine (S.A.), Program in Physical Therapy (W.T.C., S.B.R.), Diabetic Cardiovascular Disease Center (H.J., D.S.O., J.E.S., M.F.), Mallinckrodt Institute of Radiology (A.R.C., R.O'C., A.B., C.J.-N.), Gastroenterology Division (K.K., C.A.S., S.W.), Lifestyle Intervention Research Core, Cardiology Division (A.D.W., V.G.D.-R., L.R.P.), Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1210/jc.2015-3292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880128PMC
February 2016

Towards a New Diagnostic Standard for Niemann-Pick C Disease.

EBioMedicine 2016 Feb 9;4:18-9. Epub 2016 Jan 9.

Diabetic Cardiovascular Disease Center, Washington University, St. Louis, MO USA.

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http://dx.doi.org/10.1016/j.ebiom.2016.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776064PMC
February 2016

High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets.

Genet Med 2016 Jan 12;18(1):41-8. Epub 2015 Mar 12.

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/gim.2015.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486368PMC
January 2016

Phenotypic divergence in two lines of L-Fabp-/- mice reflects substrain differences and environmental modifiers.

Am J Physiol Gastrointest Liver Physiol 2015 Oct 6;309(8):G648-61. Epub 2015 Aug 6.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri

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http://www.physiology.org/doi/10.1152/ajpgi.00170.2015
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http://dx.doi.org/10.1152/ajpgi.00170.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609928PMC
October 2015

A validated LC-MS/MS assay for quantification of 24(S)-hydroxycholesterol in plasma and cerebrospinal fluid.

J Lipid Res 2015 Jun 12;56(6):1222-33. Epub 2015 Apr 12.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, MO 63110.

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http://dx.doi.org/10.1194/jlr.D058487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442878PMC
June 2015

snoRNA U17 regulates cellular cholesterol trafficking.

Cell Metab 2015 Jun 14;21(6):855-67. Epub 2015 May 14.

Diabetic Cardiovascular Disease Center and Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456254PMC
June 2015

Side-chain oxysterols modulate cholesterol accessibility through membrane remodeling.

Biochemistry 2014 May 1;53(18):3042-51. Epub 2014 May 1.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine , St. Louis, Missouri 63110, United States.

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http://dx.doi.org/10.1021/bi5000096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020583PMC
May 2014

Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid Bilayers.

J Chem Theory Comput 2014 May;10(5):2137-2150

Computational and Statistical Analytics Division, Pacific Northwest National Laboratory, Richland, Washington.

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http://dx.doi.org/10.1021/ct401028gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044725PMC
May 2014

Altered transition metal homeostasis in Niemann-Pick disease, type C1.

Metallomics 2014 Mar 16;6(3):542-53. Epub 2013 Dec 16.

Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Level 4, Kenneth Myer Building, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1039/c3mt00308fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178950PMC
March 2014

Box C/D small nucleolar RNA (snoRNA) U60 regulates intracellular cholesterol trafficking.

J Biol Chem 2013 Dec 30;288(50):35703-13. Epub 2013 Oct 30.

From the Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, Missouri 63110.

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http://dx.doi.org/10.1074/jbc.M113.488577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861622PMC
December 2013

Efficacy of N-acetylcysteine in phenotypic suppression of mouse models of Niemann-Pick disease, type C1.

Hum Mol Genet 2013 Sep 10;22(17):3508-23. Epub 2013 May 10.

Department of Health and Human Services, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://hmg.oxfordjournals.org/content/early/2013/05/09/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddt206
Publisher Site
http://dx.doi.org/10.1093/hmg/ddt206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736870PMC
September 2013

Development and validation of LC-MS/MS method for determination of very long acyl chain (C22:0 and C24:0) ceramides in human plasma.

Anal Bioanal Chem 2013 Sep 16;405(23):7357-65. Epub 2013 Jul 16.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine, Box 8086, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1007/s00216-013-7166-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766747PMC
September 2013

Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages.

J Biol Chem 2013 Feb 18;288(5):2923-32. Epub 2012 Dec 18.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M112.419978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561515PMC
February 2013

SmD3 regulates intronic noncoding RNA biogenesis.

Mol Cell Biol 2012 Oct 6;32(20):4092-103. Epub 2012 Aug 6.

Diabetic Cardiovascular Disease Center and Department of Medicine, Washington University, St. Louis, Missouri, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00022-12
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http://dx.doi.org/10.1128/MCB.00022-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457340PMC
October 2012

Microarray expression analysis and identification of serum biomarkers for Niemann-Pick disease, type C1.

Hum Mol Genet 2012 Aug 22;21(16):3632-46. Epub 2012 May 22.

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/hmg/dds193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406758PMC
August 2012

Liver X receptor agonist modulation of cholesterol efflux in mice with intestine-specific deletion of microsomal triglyceride transfer protein.

Arterioscler Thromb Vasc Biol 2012 Jul 10;32(7):1624-31. Epub 2012 May 10.

Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1161/ATVBAHA.112.246066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619218PMC
July 2012

Oxysterols as non-genomic regulators of cholesterol homeostasis.

Trends Endocrinol Metab 2012 Mar 11;23(3):99-106. Epub 2012 Jan 11.

Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104327601100190
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http://dx.doi.org/10.1016/j.tem.2011.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294026PMC
March 2012

Side-chain oxysterols: from cells to membranes to molecules.

Biochim Biophys Acta 2012 Feb 1;1818(2):330-6. Epub 2011 Jul 1.

Diabetic Cardiovascular Disease Center, Washington University in St. Louis School of Medicine, USA.

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http://dx.doi.org/10.1016/j.bbamem.2011.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197895PMC
February 2012

Synthesis of the enantiomer of the oxysterol-antagonist LY295427.

Steroids 2011 Sep-Oct;76(10-11):986-90. Epub 2011 Apr 4.

Department of Medicine, Washington University School of Medicine, 660 S. Euclid, St. Louis, MO 63110, United States.

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http://dx.doi.org/10.1016/j.steroids.2011.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139699PMC
November 2011

25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes.

Biophys J 2011 Feb;100(4):948-56

Department of Medicine, Diabetic Cardiovascular Disease Center, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1016/j.bpj.2010.12.3728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037553PMC
February 2011

Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease.

Sci Transl Med 2010 Nov;2(56):56ra81

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/scitranslmed.3001417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170139PMC
November 2010

ApoA-1 in diabetes: damaged goods.

Diabetes 2010 Oct;59(10):2358-9

Department of Medicine, Washington University School of Medicine, Diabetic Cardiovascular Disease Center, St Louis, Missouri, USA.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db10-10
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http://dx.doi.org/10.2337/db10-1040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279547PMC
October 2010

miR-33 links SREBP-2 induction to repression of sterol transporters.

Proc Natl Acad Sci U S A 2010 Jul 21;107(27):12228-32. Epub 2010 Jun 21.

Edward A Doisy Department of Biochemistry and Molecular Biology, Saint Louis University, St Louis, MO 63104, USA.

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http://dx.doi.org/10.1073/pnas.1005191107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901433PMC
July 2010

Getting a "Hold" on NPC2.

Authors:
Daniel S Ory

Cell Metab 2009 Sep;10(3):161-2

Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15504131090023
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http://dx.doi.org/10.1016/j.cmet.2009.08.006DOI Listing
September 2009

Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression.

PLoS One 2009 Sep 11;4(9):e6951. Epub 2009 Sep 11.

Dominick P. Purpura Department of Neuroscience, Rose F. Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006951PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736622PMC
September 2009

The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stress.

J Biol Chem 2009 Mar 15;284(12):7446-54. Epub 2009 Jan 15.

Center for Cardiovascular Research, Department of Internal Medicine, the Department of Cell Biology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M806209200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658040PMC
March 2009