Publications by authors named "Daniel R Weinberger"

99Publications

Missing in Action: African Ancestry Brain Research.

Neuron 2020 Aug 24;107(3):407-411. Epub 2020 Jul 24.

Morgan State University, Provost and Senior Vice President for Academic Affairs, Professor of Engineering, Baltimore, MD 21251, USA.

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http://dx.doi.org/10.1016/j.neuron.2020.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380218PMC
August 2020

Structural Magnetic Resonance Imaging All Over Again.

JAMA Psychiatry 2020 Jul 22. Epub 2020 Jul 22.

Lieber Institute for Brain Development, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1001/jamapsychiatry.2020.1941DOI Listing
July 2020

Comment on Limbic Hyperactivity in Response to Emotionally Neutral Stimuli in Schizophrenia: A Neuroimaging Meta-Analysis of the Hypervigilant Mind.

Am J Psychiatry 2020 07;177(7):639-640

Department of Psychiatry, Medstar Georgetown University Hospital, Washington, DC (Rasetti); Lieber Institute for Brain Development and Maltz Research Laboratories, Baltimore (Chen, Weinberger); Department of Neurology, Department of Neuroscience, Department of Psychiatry and Behavioral Sciences, and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore (Weinberger).

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http://dx.doi.org/10.1176/appi.ajp.2020.19090973DOI Listing
July 2020

A glioneuronal tumor with fusion.

NPJ Genom Med 2020 3;5:24. Epub 2020 Jun 3.

Department of Pathology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, 03080 Korea.

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http://dx.doi.org/10.1038/s41525-020-0131-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270112PMC
June 2020

Parietal-Prefrontal Feedforward Connectivity in Association With Schizophrenia Genetic Risk and Delusions.

Am J Psychiatry 2020 May 27:appiajp202019111176. Epub 2020 May 27.

Lieber Institute for Brain Development, Baltimore (Greenman, La, Shah, Chen, Weinberger, Tan); Clinical and Translational Neuroscience Branch, Section on Integrative Neuroimaging, Psychosis and Cognitive Studies Section, NIMH Intramural Research Program, Bethesda, Md. (Berman); Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore (Weinberger, Tan); Departments of Neurology and Neuroscience and the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore (Weinberger).

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http://dx.doi.org/10.1176/appi.ajp.2020.19111176DOI Listing
May 2020

Special Article: Translational Science Update. Pharmacological Implications of Emerging Schizophrenia Genetics: Can the Bridge From 'Genomics' to 'Therapeutics' be Defined and Traversed?

J Clin Psychopharmacol 2020 Jul/Aug;40(4):323-329

Lieber Institute for Brain Development and the Departments of Psychiatry, Neurology, Neuroscience and Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1097/JCP.0000000000001215DOI Listing
May 2020

Cortical cellular diversity and development in schizophrenia.

Mol Psychiatry 2020 May 13. Epub 2020 May 13.

Lieber Institute for Brain Development, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41380-020-0775-8DOI Listing
May 2020

The genetic architecture of the human cerebral cortex.

Authors:
Katrina L Grasby Neda Jahanshad Jodie N Painter Lucía Colodro-Conde Janita Bralten Derrek P Hibar Penelope A Lind Fabrizio Pizzagalli Christopher R K Ching Mary Agnes B McMahon Natalia Shatokhina Leo C P Zsembik Sophia I Thomopoulos Alyssa H Zhu Lachlan T Strike Ingrid Agartz Saud Alhusaini Marcio A A Almeida Dag Alnæs Inge K Amlien Micael Andersson Tyler Ard Nicola J Armstrong Allison Ashley-Koch Joshua R Atkins Manon Bernard Rachel M Brouwer Elizabeth E L Buimer Robin Bülow Christian Bürger Dara M Cannon Mallar Chakravarty Qiang Chen Joshua W Cheung Baptiste Couvy-Duchesne Anders M Dale Shareefa Dalvie Tânia K de Araujo Greig I de Zubicaray Sonja M C de Zwarte Anouk den Braber Nhat Trung Doan Katharina Dohm Stefan Ehrlich Hannah-Ruth Engelbrecht Susanne Erk Chun Chieh Fan Iryna O Fedko Sonya F Foley Judith M Ford Masaki Fukunaga Melanie E Garrett Tian Ge Sudheer Giddaluru Aaron L Goldman Melissa J Green Nynke A Groenewold Dominik Grotegerd Tiril P Gurholt Boris A Gutman Narelle K Hansell Mathew A Harris Marc B Harrison Courtney C Haswell Michael Hauser Stefan Herms Dirk J Heslenfeld New Fei Ho David Hoehn Per Hoffmann Laurena Holleran Martine Hoogman Jouke-Jan Hottenga Masashi Ikeda Deborah Janowitz Iris E Jansen Tianye Jia Christiane Jockwitz Ryota Kanai Sherif Karama Dalia Kasperaviciute Tobias Kaufmann Sinead Kelly Masataka Kikuchi Marieke Klein Michael Knapp Annchen R Knodt Bernd Krämer Max Lam Thomas M Lancaster Phil H Lee Tristram A Lett Lindsay B Lewis Iscia Lopes-Cendes Michelle Luciano Fabio Macciardi Andre F Marquand Samuel R Mathias Tracy R Melzer Yuri Milaneschi Nazanin Mirza-Schreiber Jose C V Moreira Thomas W Mühleisen Bertram Müller-Myhsok Pablo Najt Soichiro Nakahara Kwangsik Nho Loes M Olde Loohuis Dimitri Papadopoulos Orfanos John F Pearson Toni L Pitcher Benno Pütz Yann Quidé Anjanibhargavi Ragothaman Faisal M Rashid William R Reay Ronny Redlich Céline S Reinbold Jonathan Repple Geneviève Richard Brandalyn C Riedel Shannon L Risacher Cristiane S Rocha Nina Roth Mota Lauren Salminen Arvin Saremi Andrew J Saykin Fenja Schlag Lianne Schmaal Peter R Schofield Rodrigo Secolin Chin Yang Shapland Li Shen Jean Shin Elena Shumskaya Ida E Sønderby Emma Sprooten Katherine E Tansey Alexander Teumer Anbupalam Thalamuthu Diana Tordesillas-Gutiérrez Jessica A Turner Anne Uhlmann Costanza Ludovica Vallerga Dennis van der Meer Marjolein M J van Donkelaar Liza van Eijk Theo G M van Erp Neeltje E M van Haren Daan van Rooij Marie-José van Tol Jan H Veldink Ellen Verhoef Esther Walton Mingyuan Wang Yunpeng Wang Joanna M Wardlaw Wei Wen Lars T Westlye Christopher D Whelan Stephanie H Witt Katharina Wittfeld Christiane Wolf Thomas Wolfers Jing Qin Wu Clarissa L Yasuda Dario Zaremba Zuo Zhang Marcel P Zwiers Eric Artiges Amelia A Assareh Rosa Ayesa-Arriola Aysenil Belger Christine L Brandt Gregory G Brown Sven Cichon Joanne E Curran Gareth E Davies Franziska Degenhardt Michelle F Dennis Bruno Dietsche Srdjan Djurovic Colin P Doherty Ryan Espiritu Daniel Garijo Yolanda Gil Penny A Gowland Robert C Green Alexander N Häusler Walter Heindel Beng-Choon Ho Wolfgang U Hoffmann Florian Holsboer Georg Homuth Norbert Hosten Clifford R Jack MiHyun Jang Andreas Jansen Nathan A Kimbrel Knut Kolskår Sanne Koops Axel Krug Kelvin O Lim Jurjen J Luykx Daniel H Mathalon Karen A Mather Venkata S Mattay Sarah Matthews Jaqueline Mayoral Van Son Sarah C McEwen Ingrid Melle Derek W Morris Bryon A Mueller Matthias Nauck Jan E Nordvik Markus M Nöthen Daniel S O'Leary Nils Opel Marie-Laure Paillère Martinot G Bruce Pike Adrian Preda Erin B Quinlan Paul E Rasser Varun Ratnakar Simone Reppermund Vidar M Steen Paul A Tooney Fábio R Torres Dick J Veltman James T Voyvodic Robert Whelan Tonya White Hidenaga Yamamori Hieab H H Adams Joshua C Bis Stephanie Debette Charles Decarli Myriam Fornage Vilmundur Gudnason Edith Hofer M Arfan Ikram Lenore Launer W T Longstreth Oscar L Lopez Bernard Mazoyer Thomas H Mosley Gennady V Roshchupkin Claudia L Satizabal Reinhold Schmidt Sudha Seshadri Qiong Yang Marina K M Alvim David Ames Tim J Anderson Ole A Andreassen Alejandro Arias-Vasquez Mark E Bastin Bernhard T Baune Jean C Beckham John Blangero Dorret I Boomsma Henry Brodaty Han G Brunner Randy L Buckner Jan K Buitelaar Juan R Bustillo Wiepke Cahn Murray J Cairns Vince Calhoun Vaughan J Carr Xavier Caseras Svenja Caspers Gianpiero L Cavalleri Fernando Cendes Aiden Corvin Benedicto Crespo-Facorro John C Dalrymple-Alford Udo Dannlowski Eco J C de Geus Ian J Deary Norman Delanty Chantal Depondt Sylvane Desrivières Gary Donohoe Thomas Espeseth Guillén Fernández Simon E Fisher Herta Flor Andreas J Forstner Clyde Francks Barbara Franke David C Glahn Randy L Gollub Hans J Grabe Oliver Gruber Asta K Håberg Ahmad R Hariri Catharina A Hartman Ryota Hashimoto Andreas Heinz Frans A Henskens Manon H J Hillegers Pieter J Hoekstra Avram J Holmes L Elliot Hong William D Hopkins Hilleke E Hulshoff Pol Terry L Jernigan Erik G Jönsson René S Kahn Martin A Kennedy Tilo T J Kircher Peter Kochunov John B J Kwok Stephanie Le Hellard Carmel M Loughland Nicholas G Martin Jean-Luc Martinot Colm McDonald Katie L McMahon Andreas Meyer-Lindenberg Patricia T Michie Rajendra A Morey Bryan Mowry Lars Nyberg Jaap Oosterlaan Roel A Ophoff Christos Pantelis Tomas Paus Zdenka Pausova Brenda W J H Penninx Tinca J C Polderman Danielle Posthuma Marcella Rietschel Joshua L Roffman Laura M Rowland Perminder S Sachdev Philipp G Sämann Ulrich Schall Gunter Schumann Rodney J Scott Kang Sim Sanjay M Sisodiya Jordan W Smoller Iris E Sommer Beate St Pourcain Dan J Stein Arthur W Toga Julian N Trollor Nic J A Van der Wee Dennis van 't Ent Henry Völzke Henrik Walter Bernd Weber Daniel R Weinberger Margaret J Wright Juan Zhou Jason L Stein Paul M Thompson Sarah E Medland

Science 2020 03;367(6484)

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http://dx.doi.org/10.1126/science.aay6690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295264PMC
March 2020

Neural substrates of smoking and reward cue reactivity in smokers: a meta-analysis of fMRI studies.

Transl Psychiatry 2020 03 17;10(1):97. Epub 2020 Mar 17.

Peking-Tsinghua Center for Life Sciences and PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China.

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http://dx.doi.org/10.1038/s41398-020-0775-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078287PMC
March 2020

NURR1 and ERR1 Modulate the Expression of Genes of a Coexpression Network Enriched for Schizophrenia Risk.

J Neurosci 2020 01 6;40(4):932-941. Epub 2019 Dec 6.

Group of Psychiatric Neuroscience, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari 70124, Italy,

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http://dx.doi.org/10.1523/JNEUROSCI.0786-19.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975285PMC
January 2020

Genetic architecture of subcortical brain structures in 38,851 individuals.

Authors:
Claudia L Satizabal Hieab H H Adams Derrek P Hibar Charles C White Maria J Knol Jason L Stein Markus Scholz Muralidharan Sargurupremraj Neda Jahanshad Gennady V Roshchupkin Albert V Smith Joshua C Bis Xueqiu Jian Michelle Luciano Edith Hofer Alexander Teumer Sven J van der Lee Jingyun Yang Lisa R Yanek Tom V Lee Shuo Li Yanhui Hu Jia Yu Koh John D Eicher Sylvane Desrivières Alejandro Arias-Vasquez Ganesh Chauhan Lavinia Athanasiu Miguel E Rentería Sungeun Kim David Hoehn Nicola J Armstrong Qiang Chen Avram J Holmes Anouk den Braber Iwona Kloszewska Micael Andersson Thomas Espeseth Oliver Grimm Lucija Abramovic Saud Alhusaini Yuri Milaneschi Martina Papmeyer Tomas Axelsson Stefan Ehrlich Roberto Roiz-Santiañez Bernd Kraemer Asta K Håberg Hannah J Jones G Bruce Pike Dan J Stein Allison Stevens Janita Bralten Meike W Vernooij Tamara B Harris Irina Filippi A Veronica Witte Tulio Guadalupe Katharina Wittfeld Thomas H Mosley James T Becker Nhat Trung Doan Saskia P Hagenaars Yasaman Saba Gabriel Cuellar-Partida Najaf Amin Saima Hilal Kwangsik Nho Nazanin Mirza-Schreiber Konstantinos Arfanakis Diane M Becker David Ames Aaron L Goldman Phil H Lee Dorret I Boomsma Simon Lovestone Sudheer Giddaluru Stephanie Le Hellard Manuel Mattheisen Marc M Bohlken Dalia Kasperaviciute Lianne Schmaal Stephen M Lawrie Ingrid Agartz Esther Walton Diana Tordesillas-Gutierrez Gareth E Davies Jean Shin Jonathan C Ipser Louis N Vinke Martine Hoogman Tianye Jia Ralph Burkhardt Marieke Klein Fabrice Crivello Deborah Janowitz Owen Carmichael Unn K Haukvik Benjamin S Aribisala Helena Schmidt Lachlan T Strike Ching-Yu Cheng Shannon L Risacher Benno Pütz Debra A Fleischman Amelia A Assareh Venkata S Mattay Randy L Buckner Patrizia Mecocci Anders M Dale Sven Cichon Marco P Boks Mar Matarin Brenda W J H Penninx Vince D Calhoun M Mallar Chakravarty Andre F Marquand Christine Macare Shahrzad Kharabian Masouleh Jaap Oosterlaan Philippe Amouyel Katrin Hegenscheid Jerome I Rotter Andrew J Schork David C M Liewald Greig I de Zubicaray Tien Yin Wong Li Shen Philipp G Sämann Henry Brodaty Joshua L Roffman Eco J C de Geus Magda Tsolaki Susanne Erk Kristel R van Eijk Gianpiero L Cavalleri Nic J A van der Wee Andrew M McIntosh Randy L Gollub Kazima B Bulayeva Manon Bernard Jennifer S Richards Jayandra J Himali Markus Loeffler Nanda Rommelse Wolfgang Hoffmann Lars T Westlye Maria C Valdés Hernández Narelle K Hansell Theo G M van Erp Christiane Wolf John B J Kwok Bruno Vellas Andreas Heinz Loes M Olde Loohuis Norman Delanty Beng-Choon Ho Christopher R K Ching Elena Shumskaya Baljeet Singh Albert Hofman Dennis van der Meer Georg Homuth Bruce M Psaty Mark E Bastin Grant W Montgomery Tatiana M Foroud Simone Reppermund Jouke-Jan Hottenga Andrew Simmons Andreas Meyer-Lindenberg Wiepke Cahn Christopher D Whelan Marjolein M J van Donkelaar Qiong Yang Norbert Hosten Robert C Green Anbupalam Thalamuthu Sebastian Mohnke Hilleke E Hulshoff Pol Honghuang Lin Clifford R Jack Peter R Schofield Thomas W Mühleisen Pauline Maillard Steven G Potkin Wei Wen Evan Fletcher Arthur W Toga Oliver Gruber Matthew Huentelman George Davey Smith Lenore J Launer Lars Nyberg Erik G Jönsson Benedicto Crespo-Facorro Nastassja Koen Douglas N Greve André G Uitterlinden Daniel R Weinberger Vidar M Steen Iryna O Fedko Nynke A Groenewold Wiro J Niessen Roberto Toro Christophe Tzourio William T Longstreth M Kamran Ikram Jordan W Smoller Marie-Jose van Tol Jessika E Sussmann Tomas Paus Hervé Lemaître Matthias L Schroeter Bernard Mazoyer Ole A Andreassen Florian Holsboer Chantal Depondt Dick J Veltman Jessica A Turner Zdenka Pausova Gunter Schumann Daan van Rooij Srdjan Djurovic Ian J Deary Katie L McMahon Bertram Müller-Myhsok Rachel M Brouwer Hilkka Soininen Massimo Pandolfo Thomas H Wassink Joshua W Cheung Thomas Wolfers Jean-Luc Martinot Marcel P Zwiers Matthias Nauck Ingrid Melle Nicholas G Martin Ryota Kanai Eric Westman René S Kahn Sanjay M Sisodiya Tonya White Arvin Saremi Hans van Bokhoven Han G Brunner Henry Völzke Margaret J Wright Dennis van 't Ent Markus M Nöthen Roel A Ophoff Jan K Buitelaar Guillén Fernández Perminder S Sachdev Marcella Rietschel Neeltje E M van Haren Simon E Fisher Alexa S Beiser Clyde Francks Andrew J Saykin Karen A Mather Nina Romanczuk-Seiferth Catharina A Hartman Anita L DeStefano Dirk J Heslenfeld Michael W Weiner Henrik Walter Pieter J Hoekstra Paul A Nyquist Barbara Franke David A Bennett Hans J Grabe Andrew D Johnson Christopher Chen Cornelia M van Duijn Oscar L Lopez Myriam Fornage Joanna M Wardlaw Reinhold Schmidt Charles DeCarli Philip L De Jager Arno Villringer Stéphanie Debette Vilmundur Gudnason Sarah E Medland Joshua M Shulman Paul M Thompson Sudha Seshadri M Arfan Ikram

Nat Genet 2019 11 21;51(11):1624-1636. Epub 2019 Oct 21.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1038/s41588-019-0511-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055269PMC
November 2019

The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder.

Biol Psychiatry 2019 10 13;86(7):545-556. Epub 2019 Jun 13.

Department of Psychiatry, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2019.03.985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068800PMC
October 2019

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Am J Hum Genet 2019 08;105(2):334-350

Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY 11030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699140PMC
August 2019

The fetal origins of mental illness.

Am J Obstet Gynecol 2019 12 15;221(6):549-562. Epub 2019 Jun 15.

Department of Obstetrics & Gynecology and Global Health, Center for Innate Immunity and Immune Disease, Center for Emerging and Reemerging Infectious Diseases, University of Washington, Seattle, WA; Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2019.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889013PMC
December 2019

Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia.

Neuron 2019 07 4;103(2):203-216.e8. Epub 2019 Jun 4.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD 21205, USA; Center for Computational Biology, Johns Hopkins University, Baltimore, MD 21205, USA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000204PMC
July 2019

Prefrontal Coexpression of Schizophrenia Risk Genes Is Associated With Treatment Response in Patients.

Biol Psychiatry 2019 07 3;86(1):45-55. Epub 2019 Apr 3.

Group of Psychiatric Neuroscience, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Azienda Ospedaliero-Universitaria Consorziale Policlinico, Bari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.03.981DOI Listing
July 2019

The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia.

Neuropsychopharmacology 2019 08 11;44(9):1562-1569. Epub 2019 May 11.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41386-019-0410-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785707PMC
August 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-019-10160-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826PMC
May 2019

A Genetics Perspective on the Role of the (Neuro)Immune System in Schizophrenia.

Schizophr Res 2020 03 5;217:105-113. Epub 2019 Mar 5.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, United States of America; Johns Hopkins University School of Medicine, Department of Psychiatry and Behavioral Sciences, Baltimore, MD, United States of America; Johns Hopkins University School of Medicine, Department of Neurology, Baltimore, MD, United States of America; Johns Hopkins University School of Medicine, Institute of Genomics Medicine, Baltimore, MD, United States of America; Johns Hopkins University School of Medicine, Department of Neuroscience, Baltimore, MD, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728242PMC
March 2020

Polygenic Risk Scores in Clinical Schizophrenia Research.

Am J Psychiatry 2019 01;176(1):3-4

From the Lieber Institute for Brain Development and Maltz Research Laboratories, Baltimore; and the Departments of Psychiatry, Neurology, and Neuroscience and the McNusick Nathans Institute of Genomic Medicine, Johns Hopkins School of Medicine, Baltimore.

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http://dx.doi.org/10.1176/appi.ajp.2018.18111274DOI Listing
January 2019

Thinking About Schizophrenia in an Era of Genomic Medicine.

Am J Psychiatry 2019 01;176(1):12-20

The Lieber Institute for Brain Development and Maltz Research Laboratories, Baltimore; and the Departments of Psychiatry, Neurology, and Neuroscience and the McNusick Nathans Institute of Genomic Medicine, Johns Hopkins School of Medicine, Baltimore.

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http://dx.doi.org/10.1176/appi.ajp.2018.18111275DOI Listing
January 2019

Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer's disease.

Acta Neuropathol 2019 04 2;137(4):557-569. Epub 2019 Feb 2.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, 855 N Wolfe St, Suite 300, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1007/s00401-019-01966-5DOI Listing
April 2019

Neurons with Complex Karyotypes Are Rare in Aged Human Neocortex.

Cell Rep 2019 01;26(4):825-835.e7

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Child Health Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.12.107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942668PMC
January 2019

Identification and prioritization of gene sets associated with schizophrenia risk by co-expression network analysis in human brain.

Mol Psychiatry 2020 04 26;25(4):791-804. Epub 2018 Nov 26.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, 21205, USA.

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http://www.nature.com/articles/s41380-018-0304-1
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http://dx.doi.org/10.1038/s41380-018-0304-1DOI Listing
April 2020

Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening.

Bioorg Med Chem Lett 2018 10 14;28(19):3231-3235. Epub 2018 Aug 14.

Lieber Institute for Brain Development, 855 North Wolfe Street, Baltimore, MD 21205, USA; Department of Pharmacology, Johns Hopkins University School of Medicine, 855 North Wolfe Street, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.08.012DOI Listing
October 2018

Role of gamma-amino-butyric acid in the dorsal anterior cingulate in age-associated changes in cognition.

Neuropsychopharmacology 2018 10 3;43(11):2285-2291. Epub 2018 Jul 3.

Clinical and Translational Neuroscience Branch, NIMH-Intramural Research Program (IRP), Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41386-018-0134-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135795PMC
October 2018

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2018 05 29;9(1):2098. Epub 2018 May 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-018-04362-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974083PMC
May 2018

Late-Onset Alzheimer's Disease Polygenic Risk Profile Score Predicts Hippocampal Function.

Biol Psychiatry Cogn Neurosci Neuroimaging 2017 11 26;2(8):673-679. Epub 2017 Aug 26.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.bpsc.2017.08.004DOI Listing
November 2017

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

Cell Rep 2017 Nov;21(9):2597-2613

Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA; Department of Psychiatry, Hofstra Northwell School of Medicine, Hempstead, NY, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789458PMC
November 2017

Small RNAs May Answer Big Questions in Mental Illness.

Biol Psychiatry 2018 01;83(1):e1-e3

Lieber Institute for Brain Development, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2017.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749637PMC
January 2018

Genetic insights into the neurodevelopmental origins of schizophrenia.

Nat Rev Neurosci 2017 12 26;18(12):727-740. Epub 2017 Oct 26.

Lieber Institute for Brain Development and the Departments of Psychiatry, Neurology, Neuroscience and the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://www.nature.com/doifinder/10.1038/nrn.2017.125
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http://dx.doi.org/10.1038/nrn.2017.125DOI Listing
December 2017

The Dopamine D5 Receptor Is Involved in Working Memory.

Front Pharmacol 2017 6;8:666. Epub 2017 Oct 6.

Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States.

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http://journal.frontiersin.org/article/10.3389/fphar.2017.00
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http://dx.doi.org/10.3389/fphar.2017.00666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635435PMC
October 2017

Future of Days Past: Neurodevelopment and Schizophrenia.

Schizophr Bull 2017 10;43(6):1164-1168

Lieber Institute for Brain Development.

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http://academic.oup.com/schizophreniabulletin/article/43/6/1
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http://dx.doi.org/10.1093/schbul/sbx118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737209PMC
October 2017

The neurodevelopmental origins of schizophrenia in the penumbra of genomic medicine.

World Psychiatry 2017 Oct;16(3):225-226

Lieber Institute for Brain Development; Departments of Psychiatry, Neurology and Neuroscience, and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/wps.20474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608828PMC
October 2017

Neanderthal-Derived Genetic Variation Shapes Modern Human Cranium and Brain.

Sci Rep 2017 07 24;7(1):6308. Epub 2017 Jul 24.

Section on Integrative Neuroimaging, Clinical and Translational Neuroscience Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41598-017-06587-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524936PMC
July 2017

qSVA framework for RNA quality correction in differential expression analysis.

Proc Natl Acad Sci U S A 2017 07 20;114(27):7130-7135. Epub 2017 Jun 20.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD 21205.

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http://dx.doi.org/10.1073/pnas.1617384114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502589PMC
July 2017

Attacking Heterogeneity in Schizophrenia by Deriving Clinical Subgroups From Widely Available Symptom Data.

Schizophr Bull 2018 01;44(1):101-113

Clinical and Translational Neuroscience Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.

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https://academic.oup.com/schizophreniabulletin/article/44/1/
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http://dx.doi.org/10.1093/schbul/sbx039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768050PMC
January 2018

Novel genetic loci associated with hippocampal volume.

Authors:
Derrek P Hibar Hieab H H Adams Neda Jahanshad Ganesh Chauhan Jason L Stein Edith Hofer Miguel E Renteria Joshua C Bis Alejandro Arias-Vasquez M Kamran Ikram Sylvane Desrivières Meike W Vernooij Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Ashley H Beecham Alexa Beiser Manon Bernard Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Qiang Chen Christopher R K Ching Vincent Chouraki Gabriel Cuellar-Partida Fabrice Crivello Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Oliver Grimm Michael E Griswold Tulio Guadalupe Boris A Gutman Johanna Hass Unn K Haukvik David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Kjetil N Jørgensen Nazanin Karbalai Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre F Marquand Mar Matarin Karen A Mather Manuel Mattheisen David R McKay Yuri Milaneschi Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Paul Nyquist Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Lukas Pirpamer Benno Pütz Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Stefan Ropele Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Arvin Saremi Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Stella Trompet Dhananjay Vaidya Jeroen Van der Grond Sven J Van der Lee Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Katharina Wittfeld Girma Woldehawariat Christiane Wolf Thomas Wolfers Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Anton J M De Craen Eco J C De Geus Philip L De Jager Greig I De Zubicaray Ian J Deary Stéphanie Debette Charles DeCarli Norman Delanty Chantal Depondt Anita DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Christian Enzinger Susanne Erk Thomas Espeseth Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Myriam Fornage Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Asta K Håberg Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Matthew Huentelman Hilleke E Hulshoff Pol Masashi Ikeda Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Francis J McMahon Katie L McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Helena Schmidt Peter R Schofield Sigurdur Sigursson Andrew Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Arthur W Toga Bryan J Traynor Juan Troncoso Magda Tsolaki Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad van der Lugt Nic J A van der Wee Neeltje E M Van Haren Dennis van 't Ent Marie-Jose Van Tol Badri N Vardarajan Bruno Vellas Dick J Veltman Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright Ronald H Zielke Alan B Zonderman Nicholas G Martin Cornelia M Van Duijn Margaret J Wright W T Longstreth Gunter Schumann Hans J Grabe Barbara Franke Lenore J Launer Sarah E Medland Sudha Seshadri Paul M Thompson M Arfan Ikram

Nat Commun 2017 01 18;8:13624. Epub 2017 Jan 18.

Department of Epidemiology, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ncomms13624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253632PMC
January 2017

Automated Quality Assessment of Structural Magnetic Resonance Brain Images Based on a Supervised Machine Learning Algorithm.

Front Neuroinform 2016 19;10:52. Epub 2016 Dec 19.

Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of HealthBethesda, MD, USA; The Lieber Institute for Brain DevelopmentBaltimore, MD, USA; Departments of Neurology and Radiology, Johns Hopkins University School of MedicineBaltimore, MD, USA.

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http://dx.doi.org/10.3389/fninf.2016.00052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165041PMC
December 2016

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Authors:
Hieab H H Adams Derrek P Hibar Vincent Chouraki Jason L Stein Paul A Nyquist Miguel E Rentería Stella Trompet Alejandro Arias-Vasquez Sudha Seshadri Sylvane Desrivières Ashley H Beecham Neda Jahanshad Katharina Wittfeld Sven J Van der Lee Lucija Abramovic Saud Alhusaini Najaf Amin Micael Andersson Konstantinos Arfanakis Benjamin S Aribisala Nicola J Armstrong Lavinia Athanasiu Tomas Axelsson Alexa Beiser Manon Bernard Joshua C Bis Laura M E Blanken Susan H Blanton Marc M Bohlken Marco P Boks Janita Bralten Adam M Brickman Owen Carmichael M Mallar Chakravarty Ganesh Chauhan Qiang Chen Christopher R K Ching Gabriel Cuellar-Partida Anouk Den Braber Nhat Trung Doan Stefan Ehrlich Irina Filippi Tian Ge Sudheer Giddaluru Aaron L Goldman Rebecca F Gottesman Corina U Greven Oliver Grimm Michael E Griswold Tulio Guadalupe Johanna Hass Unn K Haukvik Saima Hilal Edith Hofer David Hoehn Avram J Holmes Martine Hoogman Deborah Janowitz Tianye Jia Dalia Kasperaviciute Sungeun Kim Marieke Klein Bernd Kraemer Phil H Lee Jiemin Liao David C M Liewald Lorna M Lopez Michelle Luciano Christine Macare Andre Marquand Mar Matarin Karen A Mather Manuel Mattheisen Bernard Mazoyer David R McKay Rebekah McWhirter Yuri Milaneschi Nazanin Mirza-Schreiber Ryan L Muetzel Susana Muñoz Maniega Kwangsik Nho Allison C Nugent Loes M Olde Loohuis Jaap Oosterlaan Martina Papmeyer Irene Pappa Lukas Pirpamer Sara Pudas Benno Pütz Kumar B Rajan Adaikalavan Ramasamy Jennifer S Richards Shannon L Risacher Roberto Roiz-Santiañez Nanda Rommelse Emma J Rose Natalie A Royle Tatjana Rundek Philipp G Sämann Claudia L Satizabal Lianne Schmaal Andrew J Schork Li Shen Jean Shin Elena Shumskaya Albert V Smith Emma Sprooten Lachlan T Strike Alexander Teumer Russell Thomson Diana Tordesillas-Gutierrez Roberto Toro Daniah Trabzuni Dhananjay Vaidya Jeroen Van der Grond Dennis Van der Meer Marjolein M J Van Donkelaar Kristel R Van Eijk Theo G M Van Erp Daan Van Rooij Esther Walton Lars T Westlye Christopher D Whelan Beverly G Windham Anderson M Winkler Girma Woldehawariat Christiane Wolf Thomas Wolfers Bing Xu Lisa R Yanek Jingyun Yang Alex Zijdenbos Marcel P Zwiers Ingrid Agartz Neelum T Aggarwal Laura Almasy David Ames Philippe Amouyel Ole A Andreassen Sampath Arepalli Amelia A Assareh Sandra Barral Mark E Bastin Diane M Becker James T Becker David A Bennett John Blangero Hans van Bokhoven Dorret I Boomsma Henry Brodaty Rachel M Brouwer Han G Brunner Randy L Buckner Jan K Buitelaar Kazima B Bulayeva Wiepke Cahn Vince D Calhoun Dara M Cannon Gianpiero L Cavalleri Christopher Chen Ching-Yu Cheng Sven Cichon Mark R Cookson Aiden Corvin Benedicto Crespo-Facorro Joanne E Curran Michael Czisch Anders M Dale Gareth E Davies Eco J C De Geus Philip L De Jager Greig I de Zubicaray Norman Delanty Chantal Depondt Anita L DeStefano Allissa Dillman Srdjan Djurovic Gary Donohoe Wayne C Drevets Ravi Duggirala Thomas D Dyer Susanne Erk Thomas Espeseth Denis A Evans Iryna O Fedko Guillén Fernández Luigi Ferrucci Simon E Fisher Debra A Fleischman Ian Ford Tatiana M Foroud Peter T Fox Clyde Francks Masaki Fukunaga J Raphael Gibbs David C Glahn Randy L Gollub Harald H H Göring Hans J Grabe Robert C Green Oliver Gruber Vilmundur Gudnason Sebastian Guelfi Narelle K Hansell John Hardy Catharina A Hartman Ryota Hashimoto Katrin Hegenscheid Andreas Heinz Stephanie Le Hellard Dena G Hernandez Dirk J Heslenfeld Beng-Choon Ho Pieter J Hoekstra Wolfgang Hoffmann Albert Hofman Florian Holsboer Georg Homuth Norbert Hosten Jouke-Jan Hottenga Hilleke E Hulshoff Pol Masashi Ikeda M Kamran Ikram Clifford R Jack Mark Jenkinson Robert Johnson Erik G Jönsson J Wouter Jukema René S Kahn Ryota Kanai Iwona Kloszewska David S Knopman Peter Kochunov John B Kwok Stephen M Lawrie Hervé Lemaître Xinmin Liu Dan L Longo W T Longstreth Oscar L Lopez Simon Lovestone Oliver Martinez Jean-Luc Martinot Venkata S Mattay Colm McDonald Andrew M McIntosh Katie L McMahon Francis J McMahon Patrizia Mecocci Ingrid Melle Andreas Meyer-Lindenberg Sebastian Mohnke Grant W Montgomery Derek W Morris Thomas H Mosley Thomas W Mühleisen Bertram Müller-Myhsok Michael A Nalls Matthias Nauck Thomas E Nichols Wiro J Niessen Markus M Nöthen Lars Nyberg Kazutaka Ohi Rene L Olvera Roel A Ophoff Massimo Pandolfo Tomas Paus Zdenka Pausova Brenda W J H Penninx G Bruce Pike Steven G Potkin Bruce M Psaty Simone Reppermund Marcella Rietschel Joshua L Roffman Nina Romanczuk-Seiferth Jerome I Rotter Mina Ryten Ralph L Sacco Perminder S Sachdev Andrew J Saykin Reinhold Schmidt Peter R Schofield Sigurdur Sigurdsson Andy Simmons Andrew Singleton Sanjay M Sisodiya Colin Smith Jordan W Smoller Hilkka Soininen Velandai Srikanth Vidar M Steen David J Stott Jessika E Sussmann Anbupalam Thalamuthu Henning Tiemeier Arthur W Toga Bryan J Traynor Juan Troncoso Jessica A Turner Christophe Tzourio Andre G Uitterlinden Maria C Valdés Hernández Marcel Van der Brug Aad Van der Lugt Nic J A Van der Wee Cornelia M Van Duijn Neeltje E M Van Haren Dennis Van T Ent Marie-Jose Van Tol Badri N Vardarajan Dick J Veltman Meike W Vernooij Henry Völzke Henrik Walter Joanna M Wardlaw Thomas H Wassink Michael E Weale Daniel R Weinberger Michael W Weiner Wei Wen Eric Westman Tonya White Tien Y Wong Clinton B Wright H Ronald Zielke Alan B Zonderman Ian J Deary Charles DeCarli Helena Schmidt Nicholas G Martin Anton J M De Craen Margaret J Wright Lenore J Launer Gunter Schumann Myriam Fornage Barbara Franke Stéphanie Debette Sarah E Medland M Arfan Ikram Paul M Thompson

Nat Neurosci 2016 12 3;19(12):1569-1582. Epub 2016 Oct 3.

Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nn.4398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227112PMC
December 2016

Temporal, Diagnostic, and Tissue-Specific Regulation of NRG3 Isoform Expression in Human Brain Development and Affective Disorders.

Am J Psychiatry 2017 03 24;174(3):256-265. Epub 2016 Oct 24.

From the Department of Psychiatry and the Department of Cell and Developmental Biology, School of Medicine, University of Colorado, Aurora; the Lieber Institute for Brain Development, Johns Hopkins University, Baltimore; and the Department of Psychiatry and Behavioral Sciences, the Department of Neurology, the Department of Neuroscience, and the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore.

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http://dx.doi.org/10.1176/appi.ajp.2016.16060721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892449PMC
March 2017

Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia.

Cell Rep 2016 08 11;16(8):2116-2128. Epub 2016 Aug 11.

Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001893PMC
August 2016

Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons.

Cell Stem Cell 2016 08 28;19(2):248-257. Epub 2016 Jul 28.

Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore; Department of Biochemistry, National University of Singapore, 8 Medical Drive, Singapore 117597, Singapore; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 639798, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510242PMC
August 2016

Dynamic regulation of RNA editing in human brain development and disease.

Nat Neurosci 2016 08 27;19(8):1093-9. Epub 2016 Jun 27.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/nn.4337DOI Listing
August 2016

Estimating changing contexts in schizophrenia.

Brain 2016 07 23;139(Pt 7):2082-95. Epub 2016 May 23.

1 Lieber Institute for Brain Development, Baltimore, Maryland, USA 2 Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, Maryland, USA 3 Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

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http://dx.doi.org/10.1093/brain/aww095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939701PMC
July 2016

Regional Variations in Brain Gyrification Are Associated with General Cognitive Ability in Humans.

Curr Biol 2016 05 28;26(10):1301-5. Epub 2016 Apr 28.

Section on Integrative Neuroimaging, Clinical and Translational Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA; Psychosis and Cognitive Studies Section, Clinical and Translational Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879055PMC
May 2016

Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model.

J Neurosci 2016 04;36(17):4859-75

Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, University of Colorado, School of Medicine, Department of Psychiatry, Aurora, Colorado 80045, University of Colorado, School of Medicine, Department of Cell and Developmental Biology, Aurora, Colorado 80045

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4632-15.2
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http://dx.doi.org/10.1523/JNEUROSCI.4632-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846677PMC
April 2016

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.

JAMA Psychiatry 2016 05;73(5):497-505

Schizophrenia Research Institute, Sydney, Australia23School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.0129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785705PMC
May 2016

Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1.

Neuron 2016 Apr 10;90(1):43-55. Epub 2016 Mar 10.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA; Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824652PMC
April 2016

Brain catechol-O-methyltransferase (COMT) inhibition by tolcapone counteracts recognition memory deficits in normal and chronic phencyclidine-treated rats and in COMT-Val transgenic mice.

Behav Pharmacol 2016 08;27(5):415-21

aUCB Biopharma s.p.r.l., Neuroscience Therapeutic Area, Chemin du Foriest, B-1420 Braine-l'Alleud, Belgium bLieber Institute for Brain Development Departments of cPsychiatry dNeurology eNeuroscience, Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore fClinical Brain Disorders Branch, National Institute of Mental Health, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/FBP.0000000000000208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935608PMC
August 2016

GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders.

PLoS One 2016 5;11(2):e0148558. Epub 2016 Feb 5.

The Lieber Institute for Brain Development, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148558PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744057PMC
August 2016

Prefrontal GABA Levels Measured With Magnetic Resonance Spectroscopy in Patients With Psychosis and Unaffected Siblings.

Am J Psychiatry 2016 05 22;173(5):527-34. Epub 2016 Jan 22.

From the Clinical and Translational Neuroscience Branch, NIMH-Intramural Research Program (IRP), the Magnetic Resonance Spectroscopy Core, NIMH-IRP, and the Program on Pediatric Imaging and Tissue Sciences, National Institute of Child Health and Human Development-IRP, Bethesda, Md.; the Lieber Institute for Brain Development, Baltimore; the Departments of Psychiatry, Neurology, and Neuroscience and the Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore.

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http://dx.doi.org/10.1176/appi.ajp.2015.15020190DOI Listing
May 2016

Editorial overview: Neurobiology of disease.

Curr Opin Neurobiol 2016 Feb 18;36:v-vii. Epub 2016 Jan 18.

Lieber Institute for Brain Development and Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.conb.2016.01.001DOI Listing
February 2016

Whither Research Domain Criteria (RDoC)?: The Good, the Bad, and the Ugly.

JAMA Psychiatry 2015 Dec;72(12):1161-2

Department of Child and Adolescent Psychiatry, New York University Langone Medical Center, New York5Nathan Kline Institute, Orangeburg, New York.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.1743DOI Listing
December 2015

The impact of Val108/158Met polymorphism of catechol-O-methyltransferase on brain oscillations during working memory.

Neurosci Lett 2016 Jan 1;610:86-91. Epub 2015 Nov 1.

Clinical Brain Disorders Branch, NIMH, Bldg. 10, Bethesda, MD 20892, USA; MEG Core Facility, National Institutes of Health, Bldg. 10, Bethesda, MD 20982, USA.

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http://dx.doi.org/10.1016/j.neulet.2015.10.018DOI Listing
January 2016