Publications by authors named "Daniel P Gale"

54Publications

The solution structure of the complement deregulator FHR5 reveals a compact dimer and provides new insights into CFHR5 nephropathy.

J Biol Chem 2020 Sep 14. Epub 2020 Sep 14.

Structural and Molecular Biology, University College London, United Kingdom.

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http://dx.doi.org/10.1074/jbc.RA120.015132DOI Listing
September 2020

Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.

Kidney Int 2020 Jun 28;97(6):1260-1274. Epub 2020 Feb 28.

National Renal Complement Therapeutics Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; Complement Therapeutics Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2020.01.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242908PMC
June 2020

Diagnoses of uncertain significance: kidney genetics in the 21st century.

Nat Rev Nephrol 2020 Apr 7. Epub 2020 Apr 7.

Department of Renal Medicine, University College London, London, UK.

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http://dx.doi.org/10.1038/s41581-020-0277-6DOI Listing
April 2020

Atypical haemolytic uraemic syndrome in the eculizumab era: presentation, response to treatment and evaluation of an eculizumab withdrawal strategy.

Br J Haematol 2019 07 27;186(1):113-124. Epub 2019 Mar 27.

Department of Haematology, UCLH, Cardiometabolic programme- NIHR UCLH/UCL BRC, London, UK.

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http://dx.doi.org/10.1111/bjh.15899DOI Listing
July 2019

First identification of nonsense mutations in autosomal dominant focal segmental glomerulosclerosis.

Clin Sci (Lond) 2019 01 3;133(1):9-21. Epub 2019 Jan 3.

Department of Nephrology, 97th Hospital of PLA, Xuzhou 221004, Jiangsu Province, China

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http://dx.doi.org/10.1042/CS20180676DOI Listing
January 2019

Makes Me Miserable.

J Am Soc Nephrol 2018 09 17;29(9):2257-2258. Epub 2018 Aug 17.

Division of Medicine, Department of Nephrology, University College London, London, UK

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http://dx.doi.org/10.1681/ASN.2018070742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115660PMC
September 2018

Galactosylation of IgA1 Is Associated with Common Variation in .

J Am Soc Nephrol 2017 Jul 16;28(7):2158-2166. Epub 2017 Feb 16.

Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.

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http://dx.doi.org/10.1681/ASN.2016091043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491291PMC
July 2017

Attitudes in Patients with Autosomal Dominant Polycystic Kidney Disease Toward Prenatal Diagnosis and Preimplantation Genetic Diagnosis.

Genet Test Mol Biomarkers 2016 Dec 30;20(12):741-746. Epub 2016 Sep 30.

5 Centre for Nephrology, Royal Free Hospital, University College London , London, United Kingdom .

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http://dx.doi.org/10.1089/gtmb.2016.0050DOI Listing
December 2016

Isolated microscopic haematuria of glomerular origin: clinical significance and diagnosis in the 21st century.

Clin Med (Lond) 2015 Dec;15(6):576-80

Centre for Nephrology, University College London, Royal Free Hospital, London, UK

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http://dx.doi.org/10.7861/clinmedicine.15-6-576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4953265PMC
December 2015

A novel LMX1B mutation in a family with end-stage renal disease of 'unknown cause'.

Clin Kidney J 2015 Feb 5;8(1):113-9. Epub 2014 Dec 5.

Institute of Genetic Medicine , International Centre for Life, Newcastle University , Newcastle upon Tyne , UK.

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http://dx.doi.org/10.1093/ckj/sfu129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310431PMC
February 2015

Genetic testing can resolve diagnostic confusion in Alport syndrome.

Clin Kidney J 2014 Apr 18;7(2):197-200. Epub 2013 Dec 18.

Newcastle Hospitals NHS Foundation Trust , Newcastle upon Tyne , UK ; Institute of Genetic Medicine , Newcastle University, International Centre for Life , Newcastle upon Tyne , UK.

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https://academic.oup.com/ckj/article-lookup/doi/10.1093/ckj/
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http://dx.doi.org/10.1093/ckj/sft144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970340PMC
April 2014

How benign is hematuria? Using genetics to predict prognosis.

Authors:
Daniel P Gale

Pediatr Nephrol 2013 Aug 17;28(8):1183-93. Epub 2013 Jan 17.

University College London-Centre for Nephrology, Royal Free Hospital Pond Street, London, NW3 2QG, UK.

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http://dx.doi.org/10.1007/s00467-012-2399-yDOI Listing
August 2013

C3 glomerulonephritis and CFHR5 nephropathy.

Nephrol Dial Transplant 2013 Feb 2;28(2):282-8. Epub 2012 Nov 2.

Centre for Nephrology, Division of Medicine, University College London, London, UK.

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http://dx.doi.org/10.1093/ndt/gfs441DOI Listing
February 2013

Regulating complement in the kidney: insights from CFHR5 nephropathy.

Dis Model Mech 2011 Nov;4(6):721-6

UCL Centre for Nephrology, Royal Free Hospital, London, NW3 2PF, UK.

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http://dmm.biologists.org/cgi/doi/10.1242/dmm.008052
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http://dx.doi.org/10.1242/dmm.008052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209641PMC
November 2011

The identification of CFHR5 nephropathy.

Authors:
Daniel P Gale

J R Soc Med 2011 May;104(5):186-90

Imperial College Kidney and Transplant Institute, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1258/jrsm.2011.11k013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089869PMC
May 2011

HLA has strongest association with IgA nephropathy in genome-wide analysis.

J Am Soc Nephrol 2010 Oct 1;21(10):1791-7. Epub 2010 Jul 1.

The John Walls Renal Unit, Leicester General Hospital and Department of Infection, Immunity, and Inflammation, University of Leicester, Leicester, United Kingdom.

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http://dx.doi.org/10.1681/ASN.2010010076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013538PMC
October 2010

Genetic loci influencing kidney function and chronic kidney disease.

Authors:
John C Chambers Weihua Zhang Graham M Lord Pim van der Harst Debbie A Lawlor Joban S Sehmi Daniel P Gale Mark N Wass Kourosh R Ahmadi Stephan J L Bakker Jacqui Beckmann Henk J G Bilo Murielle Bochud Morris J Brown Mark J Caulfield John M C Connell H Terence Cook Ioana Cotlarciuc George Davey Smith Ranil de Silva Guohong Deng Olivier Devuyst Lambert D Dikkeschei Nada Dimkovic Mark Dockrell Anna Dominiczak Shah Ebrahim Thomas Eggermann Martin Farrall Luigi Ferrucci Jurgen Floege Nita G Forouhi Ron T Gansevoort Xijin Han Bo Hedblad Jaap J Homan van der Heide Bouke G Hepkema Maria Hernandez-Fuentes Elina Hypponen Toby Johnson Paul E de Jong Nanne Kleefstra Vasiliki Lagou Marta Lapsley Yun Li Ruth J F Loos Jian'an Luan Karin Luttropp Céline Maréchal Olle Melander Patricia B Munroe Louise Nordfors Afshin Parsa Leena Peltonen Brenda W Penninx Esperanza Perucha Anneli Pouta Inga Prokopenko Paul J Roderick Aimo Ruokonen Nilesh J Samani Serena Sanna Martin Schalling David Schlessinger Georg Schlieper Marc A J Seelen Alan R Shuldiner Marketa Sjögren Johannes H Smit Harold Snieder Nicole Soranzo Timothy D Spector Peter Stenvinkel Michael J E Sternberg Ramasamyiyer Swaminathan Toshiko Tanaka Lielith J Ubink-Veltmaat Manuela Uda Peter Vollenweider Chris Wallace Dawn Waterworth Klaus Zerres Gerard Waeber Nicholas J Wareham Patrick H Maxwell Mark I McCarthy Marjo-Riitta Jarvelin Vincent Mooser Goncalo R Abecasis Liz Lightstone James Scott Gerjan Navis Paul Elliott Jaspal S Kooner

Nat Genet 2010 May 11;42(5):373-5. Epub 2010 Apr 11.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College of London, London, UK.

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http://dx.doi.org/10.1038/ng.566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748585PMC
May 2010

Variation in IGHMBP2 is not associated with IgA nephropathy in independent studies of UK Caucasian and Chinese Han patients.

Nephrol Dial Transplant 2010 May 22;25(5):1547-54. Epub 2009 Dec 22.

Department of Nephrology, 3rd Affiliated Hospital, Center for Genome Research, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.

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http://dx.doi.org/10.1093/ndt/gfp661DOI Listing
May 2010

The role of HIF in immunity.

Int J Biochem Cell Biol 2010 Apr 17;42(4):486-94. Epub 2009 Oct 17.

Division of Medicine, University College London, UK.

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http://dx.doi.org/10.1016/j.biocel.2009.10.012DOI Listing
April 2010

Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin.

Haematologica 2010 Mar 14;95(3):505-8. Epub 2009 Oct 14.

Renal Medicine, Imperial College London, Commonwealth Building, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK.

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http://dx.doi.org/10.3324/haematol.2009.013136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833083PMC
March 2010

Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease.

Kidney Int 2009 May 11;75(9):976-81. Epub 2009 Feb 11.

Imperial College Kidney and Transplant Institute, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/ki.2009.21DOI Listing
May 2009

End-stage renal failure associated with congenital deafness.

NDT Plus 2008 Jun 27;1(3):171-5. Epub 2008 Mar 27.

Department of Nephrology , Imperial College , London.

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http://dx.doi.org/10.1093/ndtplus/sfn019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421173PMC
June 2008

Inadvertent postdialysis anticoagulation due to heparin line locks.

Hemodial Int 2007 Oct;11(4):430-4

Department of Renal Medicine, West London Renal and Transplant Centre, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1111/j.1542-4758.2007.00213.xDOI Listing
October 2007

Steroid-responsive functional B12 deficiency in association with transcobalamin II polymorphism 776C --> G.

Eur J Haematol 2006 Jan;76(1):75-8

Department of Neurology, St Mary's Hospital, London, UK.

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http://dx.doi.org/10.1111/j.1600-0609.2005.00563.xDOI Listing
January 2006