Publications by authors named "Daniel P Beiting"

56Publications

OHMI: the ontology of host-microbiome interactions.

J Biomed Semantics 2019 12 30;10(1):25. Epub 2019 Dec 30.

Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1186/s13326-019-0217-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937947PMC
December 2019

Life cycle progression and sexual development of the apicomplexan parasite Cryptosporidium parvum.

Nat Microbiol 2019 12 2;4(12):2226-2236. Epub 2019 Sep 2.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41564-019-0539-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877471PMC
December 2019

Gut microbiota features associated with Clostridioides difficile colonization in puppies.

PLoS One 2019 30;14(8):e0215497. Epub 2019 Aug 30.

Department of Clinical Sciences, University of Pennsylvania, School of Veterinary Medicine, Kennett Square, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215497PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716646PMC
March 2020

IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors.

Immunohorizons 2019 01 15;3(1):13-25. Epub 2019 Jan 15.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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http://dx.doi.org/10.4049/immunohorizons.1800083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994206PMC
January 2019

Fibroblast activation protein restrains adipogenic differentiation and regulates matrix-mediated mTOR signaling.

Matrix Biol 2019 10 17;83:60-76. Epub 2019 Jul 17.

Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2019.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881546PMC
October 2019

Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii.

Nat Immunol 2019 01 19;20(1):64-72. Epub 2018 Nov 19.

Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.1038/s41590-018-0250-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291348PMC
January 2019

Author Correction: Involvement of Innate Immune System in Late Stages of Inherited Photoreceptor Degeneration.

Sci Rep 2018 Nov 14;8(1):17041. Epub 2018 Nov 14.

Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41598-018-35520-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235918PMC
November 2018

Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis.

Cell Host Microbe 2018 Mar 22;23(3):302-311.e3. Epub 2018 Feb 22.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, 36th and Hamilton Walk, 230 John Morgan Building, Philadelphia, PA 19104-6082, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350773PMC
March 2018

CD8 T Cells Lack Local Signals To Produce IFN-γ in the Skin during Infection.

J Immunol 2018 03 24;200(5):1737-1745. Epub 2018 Jan 24.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104;and

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http://dx.doi.org/10.4049/jimmunol.1701597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178231PMC
March 2018

Involvement of Innate Immune System in Late Stages of Inherited Photoreceptor Degeneration.

Sci Rep 2017 12 20;7(1):17897. Epub 2017 Dec 20.

Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41598-017-18236-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738376PMC
December 2017

Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation.

Cell Host Microbe 2017 Jul 29;22(1):13-24.e4. Epub 2017 Jun 29.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555377PMC
July 2017

Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner.

Sci Rep 2017 03 7;7:44182. Epub 2017 Mar 7.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/srep44182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339804PMC
March 2017

CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production.

PLoS Pathog 2017 02 13;13(2):e1006196. Epub 2017 Feb 13.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325592PMC
February 2017

Divergent Isoprenoid Biosynthesis Pathways in Species Constitute a Drug Target for Treating Infections in Companion Animals.

mSphere 2016 Sep-Oct;1(5). Epub 2016 Sep 28.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040788PMC
http://dx.doi.org/10.1128/mSphere.00258-16DOI Listing
September 2016

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion.

PLoS Negl Trop Dis 2016 09 15;10(9):e0004992. Epub 2016 Sep 15.

Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025153PMC
September 2016

Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

J Immunol 2016 08 18;197(4):1023-8. Epub 2016 Jul 18.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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http://dx.doi.org/10.4049/jimmunol.1600522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975960PMC
August 2016

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.

Mol Cell Biol 2016 Jan 25;36(7):1124-35. Epub 2016 Jan 25.

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/MCB.00988-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800802PMC
January 2016

Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury.

PLoS Pathog 2015 Dec 31;11(12):e1005347. Epub 2015 Dec 31.

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697774PMC
December 2015

Genome sequencing reveals strain dynamics of methicillin-resistant Staphylococcus aureus in the same household in the context of clinical disease in a person and a dog.

Vet Microbiol 2015 Nov 24;180(3-4):304-7. Epub 2015 Sep 24.

Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St., Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1016/j.vetmic.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618068PMC
November 2015

Complete Genome Sequence and Methylome of Staphylococcus schleiferi, an Important Cause of Skin and Ear Infections in Veterinary Medicine.

Genome Announc 2015 Sep 10;3(5). Epub 2015 Sep 10.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/genomeA.01011-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566178PMC
September 2015

Skin-resident memory CD4+ T cells enhance protection against Leishmania major infection.

J Exp Med 2015 Aug 27;212(9):1405-14. Epub 2015 Jul 27.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104

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http://www.jem.org/lookup/doi/10.1084/jem.20142101
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http://dx.doi.org/10.1084/jem.20142101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548053PMC
August 2015

Matrix metalloproteinase 9 production by monocytes is enhanced by TNF and participates in the pathology of human cutaneous Leishmaniasis.

PLoS Negl Trop Dis 2014 13;8(11):e3282. Epub 2014 Nov 13.

Serviço de Imunologia, Universidade Federal da Bahia, Salvador, Bahia, Brazil; Instituto Nacional de Ciências e Tecnologia - Doenças Tropicais, Salvador, Bahia, Brazil; Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Bahia, Brazil.

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http://dx.doi.org/10.1371/journal.pntd.0003282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230914PMC
May 2016

Protozoan parasites and type I interferons: a cold case reopened.

Authors:
Daniel P Beiting

Trends Parasitol 2014 Oct 18;30(10):491-8. Epub 2014 Aug 18.

Department of Pathobiology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2014.07.007DOI Listing
October 2014

Genomic profiling of human Leishmania braziliensis lesions identifies transcriptional modules associated with cutaneous immunopathology.

J Invest Dermatol 2015 Jan 18;135(1):94-101. Epub 2014 Jul 18.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268311PMC
January 2015

Bystander chronic infection negatively impacts development of CD8(+) T cell memory.

Immunity 2014 May;40(5):801-13

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114317PMC
May 2014

Human classical monocytes control the intracellular stage of Leishmania braziliensis by reactive oxygen species.

J Infect Dis 2014 Apr 7;209(8):1288-96. Epub 2014 Jan 7.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1093/infdis/jiu013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969552PMC
April 2014

Cytotoxic T cells mediate pathology and metastasis in cutaneous leishmaniasis.

PLoS Pathog 2013 18;9(7):e1003504. Epub 2013 Jul 18.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715507PMC
February 2014

A systems biological view of intracellular pathogens.

Immunol Rev 2011 Mar;240(1):117-28

Department of Biology, Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://doi.wiley.com/10.1111/j.1600-065X.2010.00998.x
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http://dx.doi.org/10.1111/j.1600-065X.2010.00998.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065973PMC
March 2011

Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses.

Cell Host Microbe 2010 Aug;8(2):208-18

Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.chom.2010.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963626PMC
August 2010

Combinatorial effects of interleukin 10 and interleukin 4 determine the progression of hepatic inflammation following murine enteric parasitic infection.

Hepatology 2010 Jun;51(6):2162-71

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401, USA.

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http://dx.doi.org/10.1002/hep.23576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918232PMC
June 2010

IL-10 regulates movement of intestinally derived CD4+ T cells to the liver.

J Immunol 2007 Jun;178(12):7974-83

James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.4049/jimmunol.178.12.7974DOI Listing
June 2007

Coordinated control of immunity to muscle stage Trichinella spiralis by IL-10, regulatory T cells, and TGF-beta.

J Immunol 2007 Jan;178(2):1039-47

James A. Baker Institute for Animal Health, College of Vetermiary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.4049/jimmunol.178.2.1039DOI Listing
January 2007

Synthesis of syndecan-1 by skeletal muscle cells is an early response to infection with Trichinella spiralis but is not essential for nurse cell development.

Infect Immun 2006 Mar;74(3):1941-3

James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1128/IAI.74.3.1941-1943.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1418630PMC
March 2006

Interleukin-10 limits local and body cavity inflammation during infection with muscle-stage Trichinella spiralis.

Infect Immun 2004 Jun;72(6):3129-37

James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1128/IAI.72.6.3129-3137.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC415664PMC
June 2004

A putative serine protease among the excretory-secretory glycoproteins of L1 Trichinella spiralis.

Mol Biochem Parasitol 2002 Jul;122(2):149-60

James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1016/s0166-6851(02)00094-4DOI Listing
July 2002