Daniel M Rotroff

Daniel M Rotroff

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Daniel M Rotroff

Daniel M Rotroff

Publications by authors named "Daniel M Rotroff"

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35Publications

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Assessment of Adverse Events and Their Ability to Discriminate Response to Anti-PD-1/PD-L1 Antibody Immunotherapy.

J Clin Oncol 2019 Nov 1:JCO1901712. Epub 2019 Nov 1.

Howard L. McLeod, PharmD, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; and Arshiya Mariam, Kimberly A. Schveder, and Daniel M. Rotroff, PhD, MSPH, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1200/JCO.19.01712DOI Listing
November 2019

Predictive Value of Hepatic Venous Pressure Gradient for Graft Hemodynamics in Living Donor Liver Transplantation.

Liver Transpl 2019 Jul 2;25(7):1034-1042. Epub 2019 May 2.

Department of General Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1002/lt.25471DOI Listing
July 2019

Identifying individual risk rare variants using protein structure guided local tests (POINT).

PLoS Comput Biol 2019 02 19;15(2):e1006722. Epub 2019 Feb 19.

Department of Statistics, North Carolina State University, Raleigh, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396946PMC
February 2019

Assessment of potential miRNA biomarkers of VERO-cell tumorigenicity in a new line (AGMK1-9T7) of African green monkey kidney cells.

Vaccine 2017 10 20;35(41):5503-5509. Epub 2017 Apr 20.

Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.04.004DOI Listing
October 2017

Embracing Integrative Multiomics Approaches.

Int J Genomics 2016 4;2016:1715985. Epub 2016 Sep 4.

Bioinformatics Research Center, North Carolina State University, Raleigh, NC 27607, USA; Department of Statistics, North Carolina State University, Raleigh, NC 27607, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027047PMC
http://dx.doi.org/10.1155/2016/1715985DOI Listing
October 2016

A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.

Hypertension 2016 09 5;68(3):621-9. Epub 2016 Jul 5.

From the Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics (M.H.S., Y.G., C.W.M., J.G.G., R.F.F., R.M.C.-D., J.A.J.) and Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine (T.J.G.), University of Florida, Gainesville; Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh (D.M.R., A.M.-R.); Department of Medicine, University of Maryland, Baltimore (A.L.B.); Department of Medicine, Emory University, Atlanta, GA (A.B.C.); Division of Nephrology and Hypertension, Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN (S.T.T.); Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, (E.B.); Department of Molecular and Cellular Biology and Genome Center, University of California, Davis (O.F.); and Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC (R.K.-D.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982802PMC
September 2016

Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response.

Front Genet 2016 17;7:138. Epub 2016 Aug 17.

Department of Statistics, North Carolina State UniversityRaleigh, NC, USA; Bioinformatics Research Center, North Carolina State UniversityRaleigh, NC, USA.

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http://dx.doi.org/10.3389/fgene.2016.00138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013254PMC
August 2016

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies.

Pharmacogenet Genomics 2016 07;26(7):324-33

Departments of aEpidemiology bBiostatistics, University of Alabama at Birmingham, Birmingham, Alabama cDepartment of Statistics, North Carolina State University, Raleigh dUAB Biostatistics, Diabetes Center for Research, University of North Carolina at Chapel Hill School of Medicine eUAB Epidemiology, Center for Pharmacogenomics and Individualized Therapy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina fDepartment of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota gNCState Biostatistics, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts hDepartment of Genetics, Division of Statistical Genomics, Washington University in St Louis, St Louis, Missouri iLaboratory of Statistical and Mathematical Genetics jLaboratory for Biochemistry, Molecular Phenotyping, and Microarray kInstitute for Translational Genomics and Population Sciences, Harbor-UCLA Medical Center, Torrance, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986826PMC
July 2016

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans.

Front Pharmacol 2016 14;7:135. Epub 2016 Jun 14.

Department of Psychiatry and Behavioral Sciences, Duke UniversityDurham, NC, USA; Duke Institute for Brain Sciences, Duke UniversityDurham, NC, USA.

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http://journal.frontiersin.org/Article/10.3389/fphar.2016.00
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http://dx.doi.org/10.3389/fphar.2016.00135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906013PMC
July 2016

Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses.

Environ Sci Technol 2014 10;48(15):8706-16. Epub 2014 Jul 10.

Department of Environmental Sciences and Engineering, University of North Carolina , Chapel Hill, North Carolina 27514, United States.

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http://dx.doi.org/10.1021/es502676eDOI Listing
November 2015

Development of a thyroperoxidase inhibition assay for high-throughput screening.

Chem Res Toxicol 2014 Mar 14;27(3):387-99. Epub 2014 Jan 14.

Oak Ridge Institute for Science Education Postdoctoral Fellow, ‡Integrated Systems Toxicology Division, §Mid-Continent Ecology Division, National Health and Environmental Effects Research Laboratory, and ∥National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency , Research Triangle Park, North Carolina 27711, United States.

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http://pubs.acs.org/doi/10.1021/tx400310w
Publisher Site
http://dx.doi.org/10.1021/tx400310wDOI Listing
March 2014

Binary classification of a large collection of environmental chemicals from estrogen receptor assays by quantitative structure-activity relationship and machine learning methods.

J Chem Inf Model 2013 Dec 11;53(12):3244-61. Epub 2013 Dec 11.

ORISE Postdoctoral Fellow and ‡National Center for Computational Toxicology, U.S. Environmental Protection Agency , Research Triangle Park, North Carolina 27711, United States.

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http://dx.doi.org/10.1021/ci400527bDOI Listing
December 2013

Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine.

Pharmacogenomics 2013 Dec;14(16):1929-31

Bioinformatics Research Center, Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh, NC 27695, USA.

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http://dx.doi.org/10.2217/pgs.13.178DOI Listing
December 2013

Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells.

Chem Res Toxicol 2013 Jul 10;26(7):1097-107. Epub 2013 Jun 10.

Department of Environmental Sciences and Engineering, University of North Carolina , Chapel Hill, North Carolina 27514, United States.

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http://dx.doi.org/10.1021/tx400117yDOI Listing
July 2013

Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals.

Environ Health Perspect 2013 Jan 28;121(1):7-14. Epub 2012 Sep 28.

Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1289/ehp.1205065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546348PMC
January 2013

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

Toxicol Sci 2010 Oct 16;117(2):348-58. Epub 2010 Jul 16.

National Center for Computational Toxicology, Office of Research and Development, United States Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.

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http://dx.doi.org/10.1093/toxsci/kfq220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280841PMC
October 2010

Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity.

Environ Sci Technol 2010 Aug;44(15):5979-85

National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.

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http://dx.doi.org/10.1021/es102150zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930403PMC
August 2010

In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project.

Environ Health Perspect 2010 Apr;118(4):485-92

National Center for Computational Toxicology, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.

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http://dx.doi.org/10.1289/ehp.0901392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854724PMC
April 2010

Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals.

J Toxicol Environ Health B Crit Rev 2010 Feb;13(2-4):329-46

US Environmental Protection Agency, Office of Research and Development, National Center for Computational Toxicology, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1080/10937404.2010.483949DOI Listing
February 2010

Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database.

Toxicol Sci 2009 Jul 10;110(1):181-90. Epub 2009 Apr 10.

National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.

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https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
Publisher Site
http://dx.doi.org/10.1093/toxsci/kfp080DOI Listing
July 2009