Publications by authors named "Daniel Lingwood"

37Publications

The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells.

Immunity 2020 Dec 22. Epub 2020 Dec 22.

The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA. Electronic address:

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December 2020

Defining and Manipulating B Cell Immunodominance Hierarchies to Elicit Broadly Neutralizing Antibody Responses against Influenza Virus.

Cell Syst 2020 Dec 7;11(6):573-588.e9. Epub 2020 Oct 7.

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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December 2020

A Single Human V-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood.

Cell Rep 2020 08;32(8):108065

The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA. Electronic address:

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August 2020

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

Cell 2020 05 27;181(5):1016-1035.e19. Epub 2020 Apr 27.

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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May 2020

Spontaneous Glycan Reattachment Following N-Glycanase Treatment of Influenza and HIV Vaccine Antigens.

J Proteome Res 2020 02 24;19(2):733-743. Epub 2020 Jan 24.

The Ragon Institute of Massachusetts General Hospital , The Massachusetts Institute of Technology and Harvard University , 400 Technology Square , Cambridge , Massachusetts 02139 , United States of America.

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February 2020

High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.

Cell 2019 12 28;179(7):1636-1646.e15. Epub 2019 Nov 28.

Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN 37232, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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December 2019

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation.

Sci Rep 2016 10 31;6:36298. Epub 2016 Oct 31.

The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.

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October 2016

In vitro reconstitution of B cell receptor-antigen interactions to evaluate potential vaccine candidates.

Nat Protoc 2016 Feb 7;11(2):193-213. Epub 2016 Jan 7.

The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute for Technology and Harvard University, Cambridge, Massachusetts, USA.

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February 2016

Lipocalin 2 as a membrane-reorganizing agent.

Authors:
Daniel Lingwood

Sci Signal 2014 Aug 12;7(338):pe19. Epub 2014 Aug 12.

Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.

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August 2014

Structural and genetic basis for development of broadly neutralizing influenza antibodies.

Nature 2012 Sep 29;489(7417):566-70. Epub 2012 Aug 29.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-3005, USA.

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September 2012

Molecular convergence of bacterial and eukaryotic surface order.

J Biol Chem 2011 Nov 30;286(47):40631-7. Epub 2011 Sep 30.

Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, Dresden 01307, Germany.

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November 2011

Lateral sorting in model membranes by cholesterol-mediated hydrophobic matching.

Proc Natl Acad Sci U S A 2011 Oct 19;108(40):16628-33. Epub 2011 Sep 19.

Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany.

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October 2011

Cholesterol modulates glycolipid conformation and receptor activity.

Nat Chem Biol 2011 May 3;7(5):260-2. Epub 2011 Apr 3.

Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.

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May 2011

Palmitoylation regulates raft affinity for the majority of integral raft proteins.

Proc Natl Acad Sci U S A 2010 Dec 3;107(51):22050-4. Epub 2010 Dec 3.

Max Planck Institute of Cell Biology and Genetics, 01307 Dresden, Germany.

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December 2010

Lipid rafts as a membrane-organizing principle.

Science 2010 Jan;327(5961):46-50

Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.

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January 2010

Order of lipid phases in model and plasma membranes.

Proc Natl Acad Sci U S A 2009 Sep 15;106(39):16645-50. Epub 2009 Sep 15.

Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.

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September 2009

Lipid rafts as functional heterogeneity in cell membranes.

Biochem Soc Trans 2009 Oct;37(Pt 5):955-60

Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.

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October 2009

Morphological homeostasis by autophagy.

Autophagy 2009 Oct 19;5(7):1039-40. Epub 2009 Oct 19.

Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.

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October 2009

Generation of cubic membranes by controlled homotypic interaction of membrane proteins in the endoplasmic reticulum.

J Biol Chem 2009 May 3;284(18):12041-8. Epub 2009 Mar 3.

Max Planck Institute for Molecular Cell Biology and Genetics, 01307 Dresden, Germany.

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May 2009

Plasma membranes are poised for activation of raft phase coalescence at physiological temperature.

Proc Natl Acad Sci U S A 2008 Jul 9;105(29):10005-10. Epub 2008 Jul 9.

Max Planck Institute for Molecular Cell Biology and Genetics, Technical University of Dresden, Dresden, Germany.

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July 2008

Detergent resistance as a tool in membrane research.

Nat Protoc 2007 ;2(9):2159-65

Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.

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December 2007

Regulation of fish gill Na(+)-K(+)-ATPase by selective sulfatide-enriched raft partitioning during seawater adaptation.

J Biol Chem 2005 Nov 11;280(44):36545-50. Epub 2005 Aug 11.

Department of Integrative Biology, University of Guelph, Ontario N1G 2W1, Canada.

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November 2005

Effect of globotriaosyl ceramide fatty acid alpha-hydroxylation on the binding by verotoxin 1 and verotoxin 2.

Neurochem Res 2002 Aug;27(7-8):807-13

Division of Infection, Immunity, Injury and Repair, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.

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August 2002