Publications by authors named "Daniel L Morgan"

59Publications

Hepatic Transcriptomic Patterns in the Neonatal Rat After Pentabromodiphenyl Ether Exposure.

Toxicol Pathol 2020 02 12;48(2):338-349. Epub 2019 Dec 12.

Cellular & Molecular Pathology Branch, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1177/0192623319888433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596650PMC
February 2020

Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver.

Sci Rep 2018 07 4;8(1):10138. Epub 2018 Jul 4.

Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://www.nature.com/articles/s41598-018-28356-3
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http://dx.doi.org/10.1038/s41598-018-28356-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031675PMC
July 2018

Comparative inhalation toxicity of ethyltoluene isomers in rats and mice.

Inhal Toxicol 2017 Oct - Dec;29(12-14):577-585. Epub 2018 Jan 29.

a Division of the National Toxicology Program , RTP , NC , USA.

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https://www.tandfonline.com/doi/full/10.1080/08958378.2018.1
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http://dx.doi.org/10.1080/08958378.2018.1430190DOI Listing
January 2019

Airway injury in an in vitro human epithelium-fibroblast model of diacetyl vapor exposure: diacetyl-induced basal/suprabasal spongiosis.

Inhal Toxicol 2017 06;29(7):310-321

a NTP Laboratory, Division of the National Toxicology Program (DNTP) , National Institute of Environmental Health Sciences (NIEHS) , Durham , NC , USA.

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http://dx.doi.org/10.1080/08958378.2017.1369604DOI Listing
June 2017

Pathology of diacetyl and 2,3-pentanedione airway lesions in a rat model of obliterative bronchiolitis.

Toxicology 2017 08 29;388:40-47. Epub 2016 Oct 29.

Toxicology Branch, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0300483X163025
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http://dx.doi.org/10.1016/j.tox.2016.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644391PMC
August 2017

Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl.

J Proteome Res 2017 02 9;16(2):538-549. Epub 2017 Jan 9.

National Institute of Environmental Health Sciences , Research Triangle Park, North Carolina 27709, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00672DOI Listing
February 2017

Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats.

Arch Toxicol 2017 Apr 16;91(4):1685-1696. Epub 2016 Sep 16.

Cellular and Molecular Pathology Branch, National Institute of Environmental Health Sciences, P. O. Box 12233, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1007/s00204-016-1831-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364093PMC
April 2017

Comparative pulmonary toxicity of inhaled metalworking fluids in rats and mice.

Toxicol Ind Health 2017 May 23;33(5):385-405. Epub 2016 Jun 23.

1 Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1177/0748233716653912DOI Listing
May 2017

Molecular Changes in the Nasal Cavity after N, N-dimethyl-p-toluidine Exposure.

Toxicol Pathol 2016 08 20;44(6):835-47. Epub 2016 Apr 20.

Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1177/0192623316637708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804348PMC
August 2016

Impact of Environmental Enrichment Devices on NTP In Vivo Studies.

Toxicol Pathol 2016 Feb 12;44(2):233-45. Epub 2016 Feb 12.

National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1177/0192623315625330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785058PMC
February 2016

Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats.

PLoS One 2015 24;10(2):e0118459. Epub 2015 Feb 24.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118459PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339611PMC
November 2015

Systemic uptake, albumin and hemoglobin binding of [(14)C]2,3-butanedione administered by intratracheal instillation in male Harlan Sprague Dawley rats and oropharyngeal aspiration in male B6C3F1/N mice.

Chem Biol Interact 2015 Feb 2;227:112-9. Epub 2015 Jan 2.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063503PMC
February 2015

Macrophage solubilization and cytotoxicity of indium-containing particles as in vitro correlates to pulmonary toxicity in vivo.

Toxicol Sci 2015 Mar 19;144(1):17-26. Epub 2014 Dec 19.

*NTP Laboratory, Division of the National Toxicology Program, National Institute of Environmental Health Sciences; and Alion Science and Technology Corporation, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfu273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349143PMC
March 2015

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity.

Environ Health Perspect 2015 Mar 6;123(3):237-45. Epub 2014 Nov 6.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Resources (DHHS), Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1289/ehp.1408202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348743PMC
March 2015

Macrophage solubilization and cytotoxicity of indium-containing particles in vitro.

Toxicol Sci 2013 Oct 19;135(2):414-24. Epub 2013 Jul 19.

* NTP Laboratory, Division of the National Toxicology Program, National Institute of Environmental Health Sciences and.

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http://toxsci.oxfordjournals.org/content/135/2/414.full.pdf
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http://www.toxsci.oxfordjournals.org/cgi/doi/10.1093/toxsci/
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http://dx.doi.org/10.1093/toxsci/kft154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807620PMC
October 2013

Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice.

Am J Physiol Lung Cell Mol Physiol 2012 Sep 13;303(6):L539-49. Epub 2012 Jul 13.

Intramural Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1152/ajplung.00389.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468476PMC
September 2012

Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans.

Toxicol Pathol 2012 Apr 3;40(3):448-65. Epub 2012 Jan 3.

National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1177/0192623311431946DOI Listing
April 2012

Multisite carcinogenicity and respiratory toxicity of inhaled 1-bromopropane in rats and mice.

Toxicol Pathol 2011 Oct 22;39(6):938-48. Epub 2011 Aug 22.

National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1177/0192623311416374DOI Listing
October 2011

Prostaglandin E₂ protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction.

Am J Physiol Lung Cell Mol Physiol 2011 Nov 19;301(5):L645-55. Epub 2011 Aug 19.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1152/ajplung.00176.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213994PMC
November 2011

Modulation of allergic airway inflammation by the oral pathogen Porphyromonas gingivalis.

Infect Immun 2010 Jun 22;78(6):2488-96. Epub 2010 Mar 22.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1128/IAI.01270-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876545PMC
June 2010

Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis.

Exp Lung Res 2009 Dec;35(10):858-82

Respiratory Toxicology, Laboratory of Molecular Toxicology, Environmental Toxicology Program/National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.3109/01902140902980961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928993PMC
December 2009

Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice.

J Biol Chem 2009 Apr 21;284(17):11309-17. Epub 2009 Jan 21.

NIEHS, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1074/jbc.M802400200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670136PMC
April 2009

Induction of cardiovascular pathology in a novel model of low-grade chronic inflammation.

Cardiovasc Pathol 2009 Jan-Feb;18(1):1-10. Epub 2007 Oct 24.

Department of Nutritional Sciences, Oklahoma State University, Stillwater, OK 74078, USA.

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http://dx.doi.org/10.1016/j.carpath.2007.07.011DOI Listing
December 2008

Respiratory toxicity of diacetyl in C57BL/6 mice.

Toxicol Sci 2008 May 27;103(1):169-80. Epub 2008 Jan 27.

Respiratory Toxicology, Laboratory of Molecular Toxicology, National Toxicology Program/National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfn016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669658PMC
May 2008

Biomarker identification in human pancreatic cancer sera.

Pancreas 2008 Jan;36(1):61-9

Department of Biochemistry & Molecular Biology, University of Oklahoma Health Science Center, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1097/mpa.0b013e3180d0a738DOI Listing
January 2008

Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis.

Am J Respir Cell Mol Biol 2007 Sep 11;37(3):300-8. Epub 2007 May 11.

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, NC 27709, USA.

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http://dx.doi.org/10.1165/rcmb.2007-0057OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994226PMC
September 2007

Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice.

Am J Respir Crit Care Med 2007 Apr 25;175(8):829-39. Epub 2007 Jan 25.

Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Drive, Building 101, MD D-201, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1164/rccm.200509-1527OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899292PMC
April 2007

NTP Toxicity Study Report on the atmospheric characterization, particle size, chemical composition, and workplace exposure assessment of cellulose insulation (CELLULOSEINS).

Authors:
Daniel L Morgan

Toxic Rep Ser 2006 Aug(74):1-62, A1-C2

National Toxicology Program, National Institute of Environmental Health Sciences, PO Box 12233, Research Triangle Park, NC 27709, USA.

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August 2006

Male sex hormones promote vagally mediated reflex airway responsiveness to cholinergic stimulation.

Am J Physiol Lung Cell Mol Physiol 2007 Apr 8;292(4):L908-14. Epub 2006 Dec 8.

Division of Intramural Research, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., Bldg. 101, Rm. D236, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1152/ajplung.00407.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2066189PMC
April 2007

Inhalational exposure to carbonyl sulfide produces altered brainstem auditory and somatosensory-evoked potentials in Fischer 344N rats.

Toxicol Sci 2007 Jan 1;95(1):118-35. Epub 2006 Nov 1.

Neurotoxicology Division, MD B105-05, NHEERL, ORD, USEPA, Research Triangle Park, North Carolina 27711, USA.

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http://dx.doi.org/10.1093/toxsci/kfl146DOI Listing
January 2007

Cyclooxygenase-1 overexpression decreases Basal airway responsiveness but not allergic inflammation.

J Immunol 2006 Oct;177(7):4785-93

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222891PMC
http://dx.doi.org/10.4049/jimmunol.177.7.4785DOI Listing
October 2006

Lung injury after ozone exposure is iron dependent.

Am J Physiol Lung Cell Mol Physiol 2007 Jan 11;292(1):L134-43. Epub 2006 Aug 11.

Human Studies Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, 104 Mason Farm Rd., Chapel Hill, NC 27599-7315, USA.

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http://ajplung.physiology.org/content/ajplung/292/1/L134.ful
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http://ajplung.physiology.org/cgi/doi/10.1152/ajplung.00534.
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http://dx.doi.org/10.1152/ajplung.00534.2005DOI Listing
January 2007

Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation.

J Immunol 2006 Jul;177(1):621-30

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, 111 T.W. Alexander Drive, Research Triangle Park, NC 27709, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262913PMC
http://dx.doi.org/10.4049/jimmunol.177.1.621DOI Listing
July 2006

Gestational mercury vapor exposure and diet contribute to mercury accumulation in neonatal rats.

Environ Health Perspect 2006 May;114(5):735-9

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459928PMC
http://dx.doi.org/10.1289/ehp.8754DOI Listing
May 2006

[1,2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats.

Pancreas 2005 Nov;31(4):337-43

SIDMAP, LLC, and Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA.

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http://dx.doi.org/10.1097/01.mpa.0000186524.53253.fbDOI Listing
November 2005

Interdisciplinary neurotoxicity inhalation studies: carbon disulfide and carbonyl sulfide research in F344 rats.

Toxicol Appl Pharmacol 2005 Sep;207(2 Suppl):245-50

Laboratory of Experimental Pathology, National Institute of Environmental Health Sciences, 111 Alexander Drive, South Campus, MD B3-08, PO Box 12233, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.taap.2005.02.037DOI Listing
September 2005

A comparison of the Ranson, Glasgow, and APACHE II scoring systems to a multiple organ system score in predicting patient outcome in pancreatitis.

Am J Surg 2005 Feb;189(2):219-22

Department of General Surgery, University of Oklahoma Health Sciences Center, P.O. Box 26901 WP 2140, Oklahoma City, OK 73190, USA.

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http://dx.doi.org/10.1016/j.amjsurg.2004.11.010DOI Listing
February 2005

Contribution of magnetic resonance microscopy in the 12-week neurotoxicity evaluation of carbonyl sulfide in Fischer 344 rats.

Toxicol Pathol 2004 Sep-Oct;32(5):501-10

Laboratory of Experimental Pathology, NIEHS, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1080/01926230490493918DOI Listing
January 2005

Chemical and physical characteristics of cellulose insulation particulates, and evaluation of potential acute pulmonary toxicity.

Am J Ind Med 2004 Dec;46(6):554-69

National Institute of Environmental Health Sciences and the National Toxicology Program, Research Triangle Park, North Carolina 27709, USA.

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http://doi.wiley.com/10.1002/ajim.20101
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http://dx.doi.org/10.1002/ajim.20101DOI Listing
December 2004

Neurotoxicity of carbonyl sulfide in F344 rats following inhalation exposure for up to 12 weeks.

Toxicol Appl Pharmacol 2004 Oct;200(2):131-45

Laboratory of Molecular Toxicology, NIEHS, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.taap.2004.04.013DOI Listing
October 2004

Evaluation of sensory evoked potentials in Long Evans rats gestationally exposed to mercury (Hg0) vapor.

Toxicol Sci 2004 Nov 13;82(1):193-206. Epub 2004 Aug 13.

Neurotoxicology Division, MD B105-05, NHEERL, ORD, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, NC 27711, USA.

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http://dx.doi.org/10.1093/toxsci/kfh246DOI Listing
November 2004

The role of Toll-like receptor 4 in environmental airway injury in mice.

Am J Respir Crit Care Med 2004 Jul 12;170(2):126-32. Epub 2004 Mar 12.

Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1164/rccm.200311-1499OCDOI Listing
July 2004

Carbon monoxide neurotoxicity: transient inhibition of avoidance response and delayed microglia reaction in the absence of neuronal death.

Toxicology 2003 Dec;194(1-2):51-63

Laboratory of Molecular Toxicology, NIEHS, 111 TW Alexander Drive, PO Box 12233, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.tox.2003.08.003DOI Listing
December 2003

Alveolar macrophage cytotoxicity for normal lung fibroblasts is mediated by nitric oxide release.

Toxicol In Vitro 2004 Feb;18(1):139-46

Respiratory Toxicology, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1016/j.tiv.2003.08.007DOI Listing
February 2004

Vitamin C, glutathione, or lipoic acid did not decrease brain or kidney mercury in rats exposed to mercury vapor.

J Toxicol Clin Toxicol 2003 ;41(4):339-47

Department of Molecular and Cellular Biology, The University of Arizona, Tucson, Arizona 85721-0106, USA.

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http://dx.doi.org/10.1081/clt-120022000DOI Listing
July 2003

Genomic analysis of the rat lung following elemental mercury vapor exposure.

Toxicol Sci 2003 Jul 2;74(1):174-81. Epub 2003 May 2.

Inorganic Carcinogenesis Section, NCI at NIEHS, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1093/toxsci/kfg091DOI Listing
July 2003

Effect of mercury vapor exposure on metallothionein and glutathione s-transferase gene expression in the kidney of nonpregnant, pregnant, and neonatal rats.

J Toxicol Environ Health A 2002 Sep;65(17):1273-88

Inorganic Carcinogenesis Section, Laboratory of Comparative Carcinogenesis, National Cancer Institute at National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.

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http://dx.doi.org/10.1080/152873902760125750DOI Listing
September 2002

Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis.

Am J Pathol 2002 Aug;161(2):459-70

Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institute of Health, Research Triangle Park, North Carolina 27709, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850724PMC
http://dx.doi.org/10.1016/S0002-9440(10)64202-2DOI Listing
August 2002

Effects of mercury vapor inhalation on reactive oxygen species and antioxidant enzymes in rat brain and kidney are minimal.

J Appl Toxicol 2002 May-Jun;22(3):167-72

Center for Devices and Radiological Health, Food and Drug Administration, Rockville, MD 20852, USA.

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http://dx.doi.org/10.1002/jat.844DOI Listing
October 2002