Publications by authors named "Daniel Konrad"

78Publications

Determining Reference Ranges for Total T in Dried Blood Samples for Newborn Screening.

Int J Neonatal Screen 2020 Mar 4;6(1):17. Epub 2020 Mar 4.

Swiss Newborn Screening Laboratory, Children's Research Center, University Children's Hospital Zurich, 8032 Zurich, Switzerland.

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http://dx.doi.org/10.3390/ijns6010017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422970PMC
March 2020

Depletion of ASK1 blunts stress-induced senescence in adipocytes.

Adipocyte 2020 Dec;9(1):535-541

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital , Zurich, Switzerland.

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http://dx.doi.org/10.1080/21623945.2020.1815977DOI Listing
December 2020

The controversial role of IL-6 in adipose tissue on obesity-induced dysregulation of glucose metabolism.

Am J Physiol Endocrinol Metab 2020 Sep 27;319(3):E607-E613. Epub 2020 Jul 27.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpendo.00306.2020DOI Listing
September 2020

Author Correction: Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease.

Nat Commun 2020 07 21;11(1):3706. Epub 2020 Jul 21.

Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland.

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http://dx.doi.org/10.1038/s41467-020-17520-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374752PMC
July 2020

Obesity-Induced Increase in Cystatin C Alleviates Tissue Inflammation.

Diabetes 2020 Sep 2;69(9):1927-1935. Epub 2020 Jul 2.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland

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http://dx.doi.org/10.2337/db19-1206DOI Listing
September 2020

Disease characteristics of MCT8 deficiency: an international, retrospective, multicentre cohort study.

Lancet Diabetes Endocrinol 2020 07;8(7):594-605

Academic Center For Thyroid Disease, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(20)30153-4DOI Listing
July 2020

Evidence on the effect of uncontrolled diabetes mellitus on orthodontic tooth movement. A systematic review with meta-analyses in pre-clinical in- vivo research.

Arch Oral Biol 2020 Jul 11;115:104739. Epub 2020 May 11.

Clinic of Orthodontics and Pediatric Dentistry, School of Dental Medicine, University of Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.archoralbio.2020.104739DOI Listing
July 2020

Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease.

Nat Commun 2020 04 29;11(1):2080. Epub 2020 Apr 29.

Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland.

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http://dx.doi.org/10.1038/s41467-020-15623-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190665PMC
April 2020

ASK1 inhibits browning of white adipose tissue in obesity.

Nat Commun 2020 04 2;11(1):1642. Epub 2020 Apr 2.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, CH-8032, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41467-020-15483-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118089PMC
April 2020

Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis.

EMBO Mol Med 2019 10 6;11(10):e10124. Epub 2019 Jun 6.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.15252/emmm.201810124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783644PMC
October 2019

Double variants in TSHR and DUOX2 in a patient with hypothyroidism: case report.

J Pediatr Endocrinol Metab 2019 Nov;32(11):1299-1303

Department of Paediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1515/jpem-2019-0051DOI Listing
November 2019

Intermittent fasting improves metabolic flexibility in short-term high-fat diet-fed mice.

Am J Physiol Endocrinol Metab 2019 11 10;317(5):E773-E782. Epub 2019 Sep 10.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpendo.00187.2019DOI Listing
November 2019

Adipocyte-specific gp130 signalling mediates exercise-induced weight reduction.

Int J Obes (Lond) 2020 03 29;44(3):707-714. Epub 2019 Aug 29.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41366-019-0444-7DOI Listing
March 2020

Future glycemic control of children diagnosed with type 1 diabetes mellitus at toddler and preschool/school age.

J Pediatr Endocrinol Metab 2019 Sep;32(9):929-933

Children's Research Centre, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1515/jpem-2019-0152DOI Listing
September 2019

A novel GATA6 variant in a boy with neonatal diabetes and diaphragmatic hernia: a familial case with a review of the literature.

J Pediatr Endocrinol Metab 2019 Sep;32(9):1027-1030

Department of Pediatric Endocrinology and Diabetology, and Children's Research Centre, University Children's Hospital, Zürich, Switzerland.

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http://dx.doi.org/10.1515/jpem-2019-0057DOI Listing
September 2019

The role of adipocyte-specific IL-6-type cytokine signaling in FFA and leptin release.

Adipocyte 2018 3;7(3):226-228. Epub 2018 Aug 3.

a Division of Pediatric Endocrinology and Diabetology , University Children's Hospital , Zurich , Switzerland.

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http://dx.doi.org/10.1080/21623945.2018.1493901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224188PMC
September 2019

Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.

Immunity 2018 07 26;49(1):164-177.e6. Epub 2018 Jun 26.

Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.05.005DOI Listing
July 2018

Still too little, too late? Ten years of growth hormone therapy baseline data from the NordiNet® International Outcome Study.

J Pediatr Endocrinol Metab 2018 Apr;31(5):521-532

Department of Paediatrics, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://www.degruyter.com/view/j/jpem.2018.31.issue-5/jpem-20
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http://dx.doi.org/10.1515/jpem-2017-0489DOI Listing
April 2018

IL-6-Type Cytokine Signaling in Adipocytes Induces Intestinal GLP-1 Secretion.

Diabetes 2018 01 24;67(1):36-45. Epub 2017 Oct 24.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland

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http://dx.doi.org/10.2337/db17-0637DOI Listing
January 2018

In Memoriam: Ruth Illig, MD (1924-2017).

Pediatr Endocrinol Rev 2017 Sep;15(1):2-3

Head of the department of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland, e-mail:

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http://dx.doi.org/10.17458/per.vol15.2017.tk.im.ruthIlligDOI Listing
September 2017

Iron metabolism in patients with Graves' hyperthyroidism.

Clin Endocrinol (Oxf) 2017 Nov 14;87(5):609-616. Epub 2017 Sep 14.

Division of Endocrinology and Diabetes, Luzerner Kantonsspital, Luzern, Switzerland.

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http://dx.doi.org/10.1111/cen.13450DOI Listing
November 2017

Two Siblings with the Same Severe Form of 21-Hydroxylase Deficiency But Different Growth and Menstrual Cycle Patterns.

Front Pediatr 2017 1;5:35. Epub 2017 Mar 1.

Department of Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland; Children's Research Centre, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.3389/fped.2017.00035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331061PMC
March 2017

A short bout of HFD promotes long-lasting hepatic lipid accumulation.

Adipocyte 2016 Jan-Mar;5(1):88-92. Epub 2015 Jul 17.

Division of Pediatric Endocrinology and Diabetology; Zurich, Switzerland; Children's ResearchCenter; University Children's Hospital; Zurich, Switzerland.

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http://dx.doi.org/10.1080/21623945.2015.1071454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836456PMC
May 2016

Mesenteric Fat Lipolysis Mediates Obesity-Associated Hepatic Steatosis and Insulin Resistance.

Diabetes 2016 Jan 17;65(1):140-8. Epub 2015 Sep 17.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland Children's Research Centre, University Children's Hospital, Zurich, Switzerland Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.2337/db15-0941DOI Listing
January 2016

Brain catecholamine depletion and motor impairment in a Th knock-in mouse with type B tyrosine hydroxylase deficiency.

Brain 2015 Oct 14;138(Pt 10):2948-63. Epub 2015 Aug 14.

1 Division of Metabolism, Department of Paediatrics, University of Zürich, Zürich, Switzerland 2 Affiliated with the Neuroscience Centre Zurich ZNZ, Zürich, Switzerland 3 Affiliated with the Children's Research Centre CRC, Zürich, Switzerland

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http://dx.doi.org/10.1093/brain/awv224DOI Listing
October 2015

The Aldosterone/Renin Ratio as a Diagnostic Tool for the Diagnosis of Primary Hypoaldosteronism in Newborns and Infants.

Horm Res Paediatr 2015 9;84(1):43-8. Epub 2015 May 9.

Department of Endocrinology/Diabetology, University Children's Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1159/000381852DOI Listing
May 2016

Cushing syndrome after bilateral lensectomy.

Eur J Pediatr 2015 Mar 24;174(3):399-401. Epub 2014 Dec 24.

General Paediatrics, University Children's Hospital, 8032, Zurich, Switzerland,

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http://dx.doi.org/10.1007/s00431-014-2477-1DOI Listing
March 2015

Opposing effects of reduced kidney mass on liver and skeletal muscle insulin sensitivity in obese mice.

Diabetes 2015 Apr 16;64(4):1131-41. Epub 2014 Oct 16.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland Children's Research Center, University Children's Hospital, Zurich, Switzerland Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.2337/db14-0779DOI Listing
April 2015

The gut-adipose-liver axis in the metabolic syndrome.

Physiology (Bethesda) 2014 Sep;29(5):304-13

Department of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland; Children's Research Center, University Children's Hospital, Zurich, Switzerland; and.

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http://dx.doi.org/10.1152/physiol.00014.2014DOI Listing
September 2014

Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney.

Biochim Biophys Acta 2014 Sep 10;1842(9):1870-8. Epub 2014 Jul 10.

Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Switzerland; Zurich Centre for Integrative Human Physiology, University of Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.07.001DOI Listing
September 2014

Short-term HFD does not alter lipolytic function of adipocytes.

Adipocyte 2014 Apr 8;3(2):115-20. Epub 2014 Jan 8.

Division of Pediatric Endocrinology and Diabetology; University Children's Hospital; Zurich, Switzerland ; Children's Research Center; University Children's Hospital; Zurich, Switzerland ; Zurich Center for Integrative Human Physiology; University of Zurich; Zurich, Switzerland.

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http://dx.doi.org/10.4161/adip.27575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979875PMC
April 2014

Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice.

Am J Physiol Regul Integr Comp Physiol 2014 Jun 2;306(11):R861-7. Epub 2014 Apr 2.

Department of Pediatric Endocrinology and Diabetology and Children's Research Center, University Children's Hospital, Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland; and

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http://dx.doi.org/10.1152/ajpregu.00533.2013DOI Listing
June 2014

Fas and FasL expression in human adipose tissue is related to obesity, insulin resistance, and type 2 diabetes.

J Clin Endocrinol Metab 2014 Jan 20;99(1):E36-44. Epub 2013 Dec 20.

Department of Medicine (M.B., M.F., M.S.), University of Leipzig, 04103 Leipzig, Germany; Integriertes Forschungs-und Behandlungszentrum Obesity Diseases (N.K.), Junior Research Group Animal Models, University of Leipzig, 04103 Leipzig, Germany; Division of Pediatric Endocrinology and Diabetology and Children's Research Centre (S.W., E.J.S., D.K.), University Children's Hospital, CH-8032 Zurich, Switzerland; Städtisches Klinikum Karlsruhe (M.R.S.), Clinic of Visceral Surgery, 76133 Karlsruhe, Germany; Department of Surgery (A.D.), University of Leipzig, 04103 Leipzig, Germany; and Zurich Center for Integrative Human Physiology (D.K.), University of Zurich, CH-8006 Zurich, Switzerland.

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http://dx.doi.org/10.1210/jc.2013-2488DOI Listing
January 2014

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.

Am J Physiol Endocrinol Metab 2013 Aug 4;305(3):E388-95. Epub 2013 Jun 4.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://ajpendo.physiology.org/content/ajpendo/305/3/E388.ful
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http://ajpendo.physiology.org/cgi/doi/10.1152/ajpendo.00179.
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http://dx.doi.org/10.1152/ajpendo.00179.2013DOI Listing
August 2013

Depot-specific differences in adipocyte insulin sensitivity in mice are diet- and function-dependent.

Adipocyte 2012 Jul;1(3):153-156

Division of Pediatric Endocrinology and Diabetology and the Children Research's Centre; University Children's Hospital; Zurich, Switzerland.

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http://dx.doi.org/10.4161/adip.19910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609098PMC
July 2012

Fas activates lipolysis in a Ca2+-CaMKII-dependent manner in 3T3-L1 adipocytes.

J Lipid Res 2013 Jan 21;54(1):63-70. Epub 2012 Oct 21.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, CH-8032 Zurich, Switzerland.

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http://dx.doi.org/10.1194/jlr.M028035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520541PMC
January 2013

Transient severe non-proliferative retinopathy in an adolescent with type 1 diabetes and chronic myeloid leukemia.

Pediatr Diabetes 2013 May 23;14(3):227-9. Epub 2012 Jul 23.

Department of Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://doi.wiley.com/10.1111/j.1399-5448.2012.00901.x
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http://dx.doi.org/10.1111/j.1399-5448.2012.00901.xDOI Listing
May 2013

Inverse regulation of basal lipolysis in perigonadal and mesenteric fat depots in mice.

Am J Physiol Endocrinol Metab 2012 Jan 11;302(1):E153-60. Epub 2011 Oct 11.

Dept. of Pediatric Endocrinology and Diabetology, University Children's Hospital, Steinwiesstrasse 75, Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpendo.00338.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774557PMC
January 2012

The portal theory supported by venous drainage-selective fat transplantation.

Diabetes 2011 Jan 18;60(1):56-63. Epub 2010 Oct 18.

University Children’s Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.2337/db10-0697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012197PMC
January 2011

Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt.

FEBS Lett 2010 Oct 7;584(19):4187-92. Epub 2010 Sep 7.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.febslet.2010.08.052DOI Listing
October 2010

Interleukin-1beta may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation.

Endocrinology 2010 Sep 21;151(9):4247-56. Epub 2010 Jul 21.

Department of Clinical Biochemistry, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84103, Israel.

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http://dx.doi.org/10.1210/en.2010-0340DOI Listing
September 2010

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice.

J Clin Invest 2010 Jan 1;120(1):191-202. Epub 2009 Dec 1.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Steinwiesstrasse 75, Zurich, Switzerland.

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http://dx.doi.org/10.1172/JCI38388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798678PMC
January 2010

Ovaries and female phenotype in a girl with 46,XY karyotype and mutations in the CBX2 gene.

Am J Hum Genet 2009 May 9;84(5):658-63. Epub 2009 Apr 9.

Division of Endocrinology/Diabetology, University Children's Hospital, 8032 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ajhg.2009.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680992PMC
May 2009

Improved glycemic control and lower frequency of severe hypoglycemia with insulin detemir; long-term experience in 105 children and adolescents with type 1 diabetes.

Pediatr Diabetes 2008 Aug 5;9(4 Pt 2):382-7. Epub 2008 Mar 5.

Department of Endocrinology and Diabetology, University Children's Hospital, Steinwiesstrasse 75, Zurich, Switzerland.

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http://dx.doi.org/10.1111/j.1399-5448.2008.00371.xDOI Listing
August 2008

Identification and functional analysis of a new WNT4 gene mutation among 28 adolescent girls with primary amenorrhea and müllerian duct abnormalities: a French collaborative study.

J Clin Endocrinol Metab 2008 Mar 8;93(3):895-900. Epub 2008 Jan 8.

Service d'Hormonologie, Hôpital Lapeyronie, Centre Hospitalier Universitaire Montpellier, 34295 Montpellier cedex 5, France.

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http://dx.doi.org/10.1210/jc.2007-2023DOI Listing
March 2008

Production of recombinant bacteriocin divercin V41 by high cell density Escherichia coli batch and fed-batch cultures.

Appl Microbiol Biotechnol 2007 Dec 19;77(3):525-31. Epub 2007 Sep 19.

Laboratory of Food Biotechnology, Institute of Food Science and Nutrition, ETH (Swiss Federal Institute of Technology) Zurich, LFV C20 Schmelzbergstrasse 7, CH-8092, Zurich, Switzerland.

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http://link.springer.com/content/pdf/10.1007/s00253-007-1188
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http://link.springer.com/10.1007/s00253-007-1188-1
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http://dx.doi.org/10.1007/s00253-007-1188-1DOI Listing
December 2007

Utilization of the insulin-signaling network in the metabolic actions of alpha-lipoic acid-reduction or oxidation?

Authors:
Daniel Konrad

Antioxid Redox Signal 2005 Jul-Aug;7(7-8):1032-9

Division of Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1089/ars.2005.7.1032DOI Listing
September 2005

A WNT4 mutation associated with Müllerian-duct regression and virilization in a 46,XX woman.

N Engl J Med 2004 Aug;351(8):792-8

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.1056/NEJMoa040533DOI Listing
August 2004

Effects of a topical enamel matrix derivative on skin wound healing.

Wound Repair Regen 2004 Jan-Feb;12(1):100-8

Department of Surgery, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1111/j.1067-1927.2004.012117.xDOI Listing
June 2004

Spontaneous regression of severe acquired infantile hypothyroidism associated with multiple liver hemangiomas.

Pediatrics 2003 Dec;112(6 Pt 1):1424-6

Division of Endocrinology, The Hospital for Sick Children, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1542/peds.112.6.1424DOI Listing
December 2003

Cardiac failure after initiation of insulin treatment in diabetic patients with beta-thalassemia major.

J Pediatr 2003 Oct;143(4):541-2

Division of Endocrinology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1067/S0022-3476(03)00414-1DOI Listing
October 2003

The AMP-activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle.

FASEB J 2003 Sep;17(12):1658-65

Department of Physiology and Lipid Research Unit, Laval University Hospital Research Center, Ste-Foy, Québec, G1V 4G2, Canada.

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http://dx.doi.org/10.1096/fj.02-1125comDOI Listing
September 2003