Daniel J Schaid

Daniel J Schaid

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Daniel J Schaid

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Familial recurrence risk with varying amount of family history.

Genet Epidemiol 2019 06 11;43(4):440-448. Epub 2019 Feb 11.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/gepi.22193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561475PMC
June 2019

Targeted Sequencing Study to Uncover Shared Genetic Susceptibility Between Peripheral Artery Disease and Coronary Heart Disease-Brief Report.

Arterioscler Thromb Vasc Biol 2019 Jun;39(6):1227-1233

From the Department of Cardiovascular Medicine (M.S.S., X.F., E.E.A., I.J.K.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1161/ATVBAHA.118.312128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531315PMC
June 2019

A review of kernel methods for genetic association studies.

Genet Epidemiol 2019 03 2;43(2):122-136. Epub 2019 Jan 2.

Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.

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http://doi.wiley.com/10.1002/gepi.22180
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http://dx.doi.org/10.1002/gepi.22180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375780PMC
March 2019

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2019 02;51(2):363

Institute of Cancer Research, London, UK.

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http://www.nature.com/articles/s41588-018-0330-6
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http://dx.doi.org/10.1038/s41588-018-0330-6DOI Listing
February 2019

Sex Differences in Older Adults' Immune Responses to Seasonal Influenza Vaccination.

Front Immunol 2019 27;10:180. Epub 2019 Feb 27.

Mayo Clinic Vaccine Research Group, Mayo Clinic, Rochester, MN, United States.

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http://dx.doi.org/10.3389/fimmu.2019.00180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400991PMC
February 2019

Multivariate generalized linear model for genetic pleiotropy.

Biostatistics 2019 01;20(1):111-128

Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1093/biostatistics/kxx067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296339PMC
January 2019

Current perspectives in assessing humoral immunity after measles vaccination.

Expert Rev Vaccines 2019 01 26;18(1):75-87. Epub 2018 Dec 26.

a Mayo Clinic Vaccine Research Group , Mayo Clinic , Rochester , MN , USA.

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https://www.tandfonline.com/doi/full/10.1080/14760584.2019.1
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http://dx.doi.org/10.1080/14760584.2019.1559063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413513PMC
January 2019

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry.

Nat Commun 2019 01 17;10(1):382. Epub 2019 Jan 17.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA, 90033, USA.

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http://dx.doi.org/10.1038/s41467-019-08293-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336778PMC
January 2019

A small-sample kernel association test for correlated data with application to microbiome association studies.

Genet Epidemiol 2018 12 15;42(8):772-782. Epub 2018 Sep 15.

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/gepi.22160DOI Listing
December 2018

Germline variation at 8q24 and prostate cancer risk in men of European ancestry.

Nat Commun 2018 11 5;9(1):4616. Epub 2018 Nov 5.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA, 90033, USA.

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http://www.nature.com/articles/s41467-018-06863-1
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http://dx.doi.org/10.1038/s41467-018-06863-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218483PMC
November 2018

From genome-wide associations to candidate causal variants by statistical fine-mapping.

Nat Rev Genet 2018 08;19(8):491-504

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41576-018-0016-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050137PMC
August 2018

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2018 07 11;50(7):928-936. Epub 2018 Jun 11.

Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0142-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568012PMC
July 2018

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

Authors:
Tokhir Dadaev Edward J Saunders Paul J Newcombe Ezequiel Anokian Daniel A Leongamornlert Mark N Brook Clara Cieza-Borrella Martina Mijuskovic Sarah Wakerell Ali Amin Al Olama Fredrick R Schumacher Sonja I Berndt Sara Benlloch Mahbubl Ahmed Chee Goh Xin Sheng Zhuo Zhang Kenneth Muir Koveela Govindasami Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Hakansson Catharine West Alison M Dunning Neil Burnet Lorelei Mucci Edward Giovannucci Gerald Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry Rosenstein Sarah Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Laura Fachal Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weisher Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Chavdar Slavov Vanio Mitev Matthew Parliament Sandeep Singhal Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Andrzej Kierzek Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Peter Kraft Matthew Freedman Fredrik Wiklund Stephen Chanock Brian E Henderson Douglas F Easton Christopher A Haiman Rosalind A Eeles David V Conti Zsofia Kote-Jarai

Nat Commun 2018 06 11;9(1):2256. Epub 2018 Jun 11.

The Institute of Cancer Research, London, SW7 3RP, UK.

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http://dx.doi.org/10.1038/s41467-018-04109-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995836PMC
June 2018

Immunoglobulin GM and KM genes and measles vaccine-induced humoral immunity.

Vaccine 2017 10 6;35(41):5444-5447. Epub 2017 Mar 6.

Mayo Clinic Vaccine Research Group, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.02.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587382PMC
October 2017

A genotype: sex interaction is associated with abdominal aortic aneurysm expansion.

J Investig Med 2017 10 11;65(7):1077-1082. Epub 2017 Jul 11.

Department of Cardiovascular Diseases and the Gonda Vascular Center, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1136/jim-2016-000404DOI Listing
October 2017

Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA.

BMC Genomics 2017 05 26;18(1):413. Epub 2017 May 26.

Department of Biostatistics, Harvard T.H. School of Public Health, 677 Huntington Ave, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12864-017-3808-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446715PMC
May 2017

Genome-wide associations of CD46 and IFI44L genetic variants with neutralizing antibody response to measles vaccine.

Hum Genet 2017 04 13;136(4):421-435. Epub 2017 Mar 13.

Mayo Clinic Vaccine Research Group, Mayo Clinic, Guggenheim 611C, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s00439-017-1768-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433429PMC
April 2017

Heritability of vaccine-induced measles neutralizing antibody titers.

Vaccine 2017 03 8;35(10):1390-1394. Epub 2017 Feb 8.

Mayo Clinic Vaccine Research Group, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.01.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548390PMC
March 2017

Polygenic risk scores in familial Alzheimer disease.

Neurology 2017 Mar 17;88(12):1180-1186. Epub 2017 Feb 17.

From the Taub Institute for Research on Alzheimer's Disease and the Aging Brain (G.T., J.M., R.O., N.S., Y.S., R.M.), Gertrude H. Sergievsky Center (G.T., J.M., N.S., Y.S., R.M.), and Department of Neurology (G.T., J.M., R.O., N.S., Y.S.), Columbia University College of Physicians and Surgeons, New York; New York Presbyterian Hospital (G.T., J.M., R.O., N.S., Y.S.), NY; Departments of Neurology and Medicine (T.D.B., D.T.), University of Washington, Seattle; Rush Alzheimer's Disease Center (D.A.B.), Rush University Medical Center, Chicago, IL; Department of Neurology (B.F.B.), Mayo Clinic, Rochester, MN; Hope Center for Neurological Disorders (C.C.), Washington University, St Louis, MO; Department of Medical and Molecular Genetics (K.F., T.M.F.), Indiana University; Department of Neurology (M.F.), Indiana University Center for Alzheimer's Disease and Related Disorders, Indianapolis; Department of Neuroscience (A.M.G., S.B.), Mount Sinai School of Medicine, New York, NY; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; School of Medicine (M.M., R.M.), Mother and Teacher Pontifical Catholic University, Santiago, Dominican Republic; Department of Medicine (R.L.) and Department of Epidemiology, Mailman School of Public Health (R.O., N.S.), Columbia University, New York; Division of Epidemiology (R.O.), New York State Psychiatric Institute, New York; Department of Neurology and Neurotherapeutics (R.R.), The University of Texas Southwestern Medical Center, Dallas; Department of Health Sciences Research (D.J.S.), Mayo Clinic, Rochester, MN; and Department of Psychiatry, Neurology and Epidemiology (R.A.S.), University of Pittsburgh, PA.

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http://dx.doi.org/10.1212/WNL.0000000000003734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373783PMC
March 2017

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.

Authors:
Melissa C Southey David E Goldgar Robert Winqvist Katri Pylkäs Fergus Couch Marc Tischkowitz William D Foulkes Joe Dennis Kyriaki Michailidou Elizabeth J van Rensburg Tuomas Heikkinen Heli Nevanlinna John L Hopper Thilo Dörk Kathleen Bm Claes Jorge Reis-Filho Zhi Ling Teo Paolo Radice Irene Catucci Paolo Peterlongo Helen Tsimiklis Fabrice A Odefrey James G Dowty Marjanka K Schmidt Annegien Broeks Frans B Hogervorst Senno Verhoef Jane Carpenter Christine Clarke Rodney J Scott Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Julian Peto Isabel Dos-Santos-Silva Olivia Fletcher Nichola Johnson Manjeet K Bolla Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Federik Marme Barbara Burwinkel Rongxi Yang Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Stig Bojesen Sune F Nielsen Henrik Flyger Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Hoda Anton-Culver Susan Neuhausen Argyrios Ziogas Christina A Clarke Hermann Brenner Volker Arndt Christa Stegmaier Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Taru A Muranen Kristiina Aittomäki Carl Blomqvist Natalia V Bogdanova Natalia N Antonenkova Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Amanda B Spurdle kConFab Investigators Els Wauters Dominiek Smeets Benoit Beuselinck Giuseppe Floris Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Janet E Olson Celine Vachon Vernon S Pankratz Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Vessela Kristensen Grethe Grenaker Alnæs Wei Zheng David J Hunter Sara Lindstrom Susan E Hankinson Peter Kraft Irene Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Arja Jukkola-Vuorinen Mervi Grip Saila Kauppila Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Antoinette Hollestelle Montserrat Garcia-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hatef Darabi Mikael Eriksson Diana M Eccles Sajjad Rafiq William J Tapper Sue M Gerty Maartje J Hooning John W M Martens J Margriet Collée Madeleine Tilanus-Linthorst Per Hall Jingmei Li Judith S Brand Keith Humphreys Angela Cox Malcolm W R Reed Craig Luccarini Caroline Baynes Alison M Dunning Ute Hamann Diana Torres Hans Ulrich Ulmer Thomas Rüdiger Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Jacques Simard Martine Dumont Penny Soucy Rosalind Eeles Kenneth Muir Fredrik Wiklund Henrik Gronberg Johanna Schleutker Børge G Nordestgaard Maren Weischer Ruth C Travis David Neal Jenny L Donovan Freddie C Hamdy Kay-Tee Khaw Janet L Stanford William J Blot Stephen Thibodeau Daniel J Schaid Joseph L Kelley Christiane Maier Adam S Kibel Cezary Cybulski Lisa Cannon-Albright Katja Butterbach Jong Park Radka Kaneva Jyotsna Batra Manuel R Teixeira Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Stefan P Renner Arndt Hartmann Alexander Hein Matthias Ruebner Diether Lambrechts Els Van Nieuwenhuysen Ignace Vergote Sandrina Lambretchs Jennifer A Doherty Mary Anne Rossing Stefan Nickels Ursula Eilber Shan Wang-Gohrke Kunle Odunsi Lara E Sucheston-Campbell Grace Friel Galina Lurie Jeffrey L Killeen Lynne R Wilkens Marc T Goodman Ingo Runnebaum Peter A Hillemanns Liisa M Pelttari Ralf Butzow Francesmary Modugno Robert P Edwards Roberta B Ness Kirsten B Moysich Andreas du Bois Florian Heitz Philipp Harter Stefan Kommoss Beth Y Karlan Christine Walsh Jenny Lester Allan Jensen Susanne Krüger Kjaer Estrid Høgdall Bernard Peissel Bernardo Bonanni Loris Bernard Ellen L Goode Brooke L Fridley Robert A Vierkant Julie M Cunningham Melissa C Larson Zachary C Fogarty Kimberly R Kalli Dong Liang Karen H Lu Michelle A T Hildebrandt Xifeng Wu Douglas A Levine Fanny Dao Maria Bisogna Andrew Berchuck Edwin S Iversen Jeffrey R Marks Lucy Akushevich Daniel W Cramer Joellen Schildkraut Kathryn L Terry Elizabeth M Poole Meir Stampfer Shelley S Tworoger Elisa V Bandera Irene Orlow Sara H Olson Line Bjorge Helga B Salvesen Anne M van Altena Katja K H Aben Lambertus A Kiemeney Leon F A G Massuger Tanja Pejovic Yukie Bean Angela Brooks-Wilson Linda E Kelemen Linda S Cook Nhu D Le Bohdan Górski Jacek Gronwald Janusz Menkiszak Claus K Høgdall Lene Lundvall Lotte Nedergaard Svend Aage Engelholm Ed Dicks Jonathan Tyrer Ian Campbell Iain McNeish James Paul Nadeem Siddiqui Rosalind Glasspool Alice S Whittemore Joseph H Rothstein Valerie McGuire Weiva Sieh Hui Cai Xiao-Ou Shu Rachel T Teten Rebecca Sutphen John R McLaughlin Steven A Narod Catherine M Phelan Alvaro N Monteiro David Fenstermacher Hui-Yi Lin Jennifer B Permuth Thomas A Sellers Y Ann Chen Ya-Yu Tsai Zhihua Chen Aleksandra Gentry-Maharaj Simon A Gayther Susan J Ramus Usha Menon Anna H Wu Celeste L Pearce David Van Den Berg Malcolm C Pike Agnieszka Dansonka-Mieszkowska Joanna Plisiecka-Halasa Joanna Moes-Sosnowska Jolanta Kupryjanczyk Paul Dp Pharoah Honglin Song Ingrid Winship Georgia Chenevix-Trench Graham G Giles Sean V Tavtigian Doug F Easton Roger L Milne

J Med Genet 2016 12 5;53(12):800-811. Epub 2016 Sep 5.

Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1136/jmedgenet-2016-103839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200636PMC
December 2016

Incorporating Functional Annotations for Fine-Mapping Causal Variants in a Bayesian Framework Using Summary Statistics.

Genetics 2016 11 21;204(3):933-958. Epub 2016 Sep 21.

Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic, Rochester, Minnesota 55905

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http://dx.doi.org/10.1534/genetics.116.188953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105870PMC
November 2016

Statistical Methods for Testing Genetic Pleiotropy.

Genetics 2016 Oct 15;204(2):483-497. Epub 2016 Aug 15.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905.

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http://dx.doi.org/10.1534/genetics.116.189308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068841PMC
October 2016

The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.

JAMA Neurol 2016 Oct;73(10):1231-1237

Taub Institute for Research on Alzheimer's Disease, The Aging Brain and the Gertrude H. Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, New York2Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York3New York Presbyterian Hospital in New York City14Department of Epidemiology, Columbia University, New York, New York.

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http://dx.doi.org/10.1001/jamaneurol.2016.2539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155512PMC
October 2016

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

Authors:
Siddhartha P Kar Jonathan Beesley Ali Amin Al Olama Kyriaki Michailidou Jonathan Tyrer ZSofia Kote-Jarai Kate Lawrenson Sara Lindstrom Susan J Ramus Deborah J Thompson Adam S Kibel Agnieszka Dansonka-Mieszkowska Agnieszka Michael Aida K Dieffenbach Aleksandra Gentry-Maharaj Alice S Whittemore Alicja Wolk Alvaro Monteiro Ana Peixoto Andrzej Kierzek Angela Cox Anja Rudolph Anna Gonzalez-Neira Anna H Wu Annika Lindblom Anthony Swerdlow Argyrios Ziogas Arif B Ekici Barbara Burwinkel Beth Y Karlan Børge G Nordestgaard Carl Blomqvist Catherine Phelan Catriona McLean Celeste Leigh Pearce Celine Vachon Cezary Cybulski Chavdar Slavov Christa Stegmaier Christiane Maier Christine B Ambrosone Claus K Høgdall Craig C Teerlink Daehee Kang Daniel C Tessier Daniel J Schaid Daniel O Stram Daniel W Cramer David E Neal Diana Eccles Dieter Flesch-Janys Digna R Velez Edwards Dominika Wokozorczyk Douglas A Levine Drakoulis Yannoukakos Elinor J Sawyer Elisa V Bandera Elizabeth M Poole Ellen L Goode Elza Khusnutdinova Estrid Høgdall Fengju Song Fiona Bruinsma Florian Heitz Francesmary Modugno Freddie C Hamdy Fredrik Wiklund Graham G Giles Håkan Olsson Hans Wildiers Hans-Ulrich Ulmer Hardev Pandha Harvey A Risch Hatef Darabi Helga B Salvesen Heli Nevanlinna Henrik Gronberg Hermann Brenner Hiltrud Brauch Hoda Anton-Culver Honglin Song Hui-Yi Lim Iain McNeish Ian Campbell Ignace Vergote Jacek Gronwald Jan Lubiński Janet L Stanford Javier Benítez Jennifer A Doherty Jennifer B Permuth Jenny Chang-Claude Jenny L Donovan Joe Dennis Joellen M Schildkraut Johanna Schleutker John L Hopper Jolanta Kupryjanczyk Jong Y Park Jonine Figueroa Judith A Clements Julia A Knight Julian Peto Julie M Cunningham Julio Pow-Sang Jyotsna Batra Kamila Czene Karen H Lu Kathleen Herkommer Kay-Tee Khaw Keitaro Matsuo Kenneth Muir Kenneth Offitt Kexin Chen Kirsten B Moysich Kristiina Aittomäki Kunle Odunsi Lambertus A Kiemeney Leon F A G Massuger Liesel M Fitzgerald Linda S Cook Lisa Cannon-Albright Maartje J Hooning Malcolm C Pike Manjeet K Bolla Manuel Luedeke Manuel R Teixeira Marc T Goodman Marjanka K Schmidt Marjorie Riggan Markus Aly Mary Anne Rossing Matthias W Beckmann Matthieu Moisse Maureen Sanderson Melissa C Southey Michael Jones Michael Lush Michelle A T Hildebrandt Ming-Feng Hou Minouk J Schoemaker Montserrat Garcia-Closas Natalia Bogdanova Nazneen Rahman Nhu D Le Nick Orr Nicolas Wentzensen Nora Pashayan Paolo Peterlongo Pascal Guénel Paul Brennan Paula Paulo Penelope M Webb Per Broberg Peter A Fasching Peter Devilee Qin Wang Qiuyin Cai Qiyuan Li Radka Kaneva Ralf Butzow Reidun Kristin Kopperud Rita K Schmutzler Robert A Stephenson Robert J MacInnis Robert N Hoover Robert Winqvist Roberta Ness Roger L Milne Ruth C Travis Sara Benlloch Sara H Olson Shannon K McDonnell Shelley S Tworoger Sofia Maia Sonja Berndt Soo Chin Lee Soo-Hwang Teo Stephen N Thibodeau Stig E Bojesen Susan M Gapstur Susanne Krüger Kjær Tanja Pejovic Teuvo L J Tammela Thilo Dörk Thomas Brüning Tiina Wahlfors Tim J Key Todd L Edwards Usha Menon Ute Hamann Vanio Mitev Veli-Matti Kosma Veronica Wendy Setiawan Vessela Kristensen Volker Arndt Walther Vogel Wei Zheng Weiva Sieh William J Blot Wojciech Kluzniak Xiao-Ou Shu Yu-Tang Gao Fredrick Schumacher Matthew L Freedman Andrew Berchuck Alison M Dunning Jacques Simard Christopher A Haiman Amanda Spurdle Thomas A Sellers David J Hunter Brian E Henderson Peter Kraft Stephen J Chanock Fergus J Couch Per Hall Simon A Gayther Douglas F Easton Georgia Chenevix-Trench Rosalind Eeles Paul D P Pharoah Diether Lambrechts

Cancer Discov 2016 09 17;6(9):1052-67. Epub 2016 Jul 17.

VIB Vesalius Research Center, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1158/2159-8290.CD-15-1227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010513PMC
September 2016

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.

Authors:
Alexander Gusev Huwenbo Shi Gleb Kichaev Mark Pomerantz Fugen Li Henry W Long Sue A Ingles Rick A Kittles Sara S Strom Benjamin A Rybicki Barbara Nemesure William B Isaacs Wei Zheng Curtis A Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Esther M John Adam B Murphy Lisa B Signorello John Carpten M Cristina Leske Suh-Yuh Wu Anslem J M Hennis Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein John S Witte Graham Casey Sam Kaggwa Michael B Cook Daniel O Stram William J Blot Rosalind A Eeles Douglas Easton Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Kenneth Muir Graham G Giles Melissa C Southey Liesel M Fitzgerald Henrik Gronberg Fredrik Wiklund Markus Aly Brian E Henderson Johanna Schleutker Tiina Wahlfors Teuvo L J Tammela Børge G Nordestgaard Tim J Key Ruth C Travis David E Neal Jenny L Donovan Freddie C Hamdy Paul Pharoah Nora Pashayan Kay-Tee Khaw Janet L Stanford Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Christiane Maier Walther Vogel Manuel Luedeke Kathleen Herkommer Adam S Kibel Cezary Cybulski Dominika Wokolorczyk Wojciech Kluzniak Lisa Cannon-Albright Craig Teerlink Hermann Brenner Aida K Dieffenbach Volker Arndt Jong Y Park Thomas A Sellers Hui-Yi Lin Chavdar Slavov Radka Kaneva Vanio Mitev Jyotsna Batra Amanda Spurdle Judith A Clements Manuel R Teixeira Hardev Pandha Agnieszka Michael Paula Paulo Sofia Maia Andrzej Kierzek David V Conti Demetrius Albanes Christine Berg Sonja I Berndt Daniele Campa E David Crawford W Ryan Diver Susan M Gapstur J Michael Gaziano Edward Giovannucci Robert Hoover David J Hunter Mattias Johansson Peter Kraft Loic Le Marchand Sara Lindström Carmen Navarro Kim Overvad Elio Riboli Afshan Siddiq Victoria L Stevens Dimitrios Trichopoulos Paolo Vineis Meredith Yeager Gosia Trynka Soumya Raychaudhuri Frederick R Schumacher Alkes L Price Matthew L Freedman Christopher A Haiman Bogdan Pasaniuc

Nat Commun 2016 Apr 7;7:10979. Epub 2016 Apr 7.

Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ncomms10979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829663PMC
April 2016

A multi-locus genetic risk score for abdominal aortic aneurysm.

Atherosclerosis 2016 Mar 5;246:274-9. Epub 2016 Jan 5.

Division of Cardiovascular Diseases and the Gonda Vascular Center, Mayo Clinic, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.12.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507075PMC
March 2016

Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial).

Circulation 2016 Mar 25;133(12):1181-8. Epub 2016 Feb 25.

From the Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, MN (I.J.K., H.J., E.E.A., S.-A.B., T.M.K., I.N.I., R.A.H., T.S.M., K.S.); Department of Health Sciences Research, Mayo Clinic, Rochester, MN (J.E.O., D.J.S., K.R.B.); Department of Pediatrics, Medicine and Physiology, Medical College of Wisconsin, Milwaukee (U.B.); Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (R.C.G.); and Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, MN (V.M.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803581PMC
March 2016

Small Sample Kernel Association Tests for Human Genetic and Microbiome Association Studies.

Genet Epidemiol 2016 Jan 7;40(1):5-19. Epub 2015 Dec 7.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1002/gepi.21934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679685PMC
January 2016

Genome-wide association study of prostate cancer-specific survival.

Cancer Epidemiol Biomarkers Prev 2015 Nov 25;24(11):1796-800. Epub 2015 Aug 25.

Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674990PMC
November 2015

Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families.

Neurobiol Aging 2015 Nov 15;36(11):3116.e9-3116.e16. Epub 2015 Aug 15.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA; Gertrude H. Sergievsky Center, Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA; Department of Neurology, Columbia University Medical Center and New York Presbyterian Hospital, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609604PMC
November 2015

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.

Hum Mol Genet 2015 Oct 29;24(19):5589-602. Epub 2015 May 29.

Division of Genetics and Epidemiology, The Institute of Cancer Research & Royal Marsden NHS Foundation Trust, London, UK,

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http://dx.doi.org/10.1093/hmg/ddv203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572072PMC
October 2015

Lessons learned in the analysis of high-dimensional data in vaccinomics.

Vaccine 2015 Sep 6;33(40):5262-70. Epub 2015 May 6.

Mayo Clinic Vaccine Research Group, Mayo Clinic, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.04.088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581898PMC
September 2015

Inbreeding among Caribbean Hispanics from the Dominican Republic and its effects on risk of Alzheimer disease.

Genet Med 2015 Aug 13;17(8):639-43. Epub 2014 Nov 13.

1] The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA [2] The Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA [3] Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA [4] Department of Neurology, Columbia University, New York, New York, USA [5] Department of Psychiatry, School of Public Health, Columbia University, New York, New York, USA.

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http://www.nature.com/doifinder/10.1038/gim.2014.161
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http://dx.doi.org/10.1038/gim.2014.161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430451PMC
August 2015

A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.

Cancer Discov 2015 Aug 1;5(8):878-91. Epub 2015 Jun 1.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California. Institute for Human Genetics, University of California, San Francisco, San Francisco, California. Department of Urology, University of California, San Francisco, San Francisco, California. UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527942PMC
August 2015

Genomic similarity and kernel methods II: methods for genomic information.

Authors:
Daniel J Schaid

Hum Hered 2010 3;70(2):132-40. Epub 2010 Jul 3.

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minn., USA.

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June 2015

Genomic similarity and kernel methods I: advancements by building on mathematical and statistical foundations.

Authors:
Daniel J Schaid

Hum Hered 2010 3;70(2):109-31. Epub 2010 Jul 3.

Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minn., USA.

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June 2015

A powerful nonparametric statistical framework for family-based association analyses.

Genetics 2015 May 5;200(1):69-78. Epub 2015 Mar 5.

Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan 48824

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http://dx.doi.org/10.1534/genetics.115.175174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423382PMC
May 2015

The kinship2 R package for pedigree data.

Hum Hered 2014 29;78(2):91-3. Epub 2014 Jul 29.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minn., USA.

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http://dx.doi.org/10.1159/000363105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154601PMC
April 2015

Kernel methods for large-scale genomic data analysis.

Brief Bioinform 2015 Mar 22;16(2):183-92. Epub 2014 Jul 22.

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http://dx.doi.org/10.1093/bib/bbu024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375394PMC
March 2015

Case-only exome sequencing and complex disease susceptibility gene discovery: study design considerations.

J Med Genet 2015 Jan 4;52(1):10-6. Epub 2014 Nov 4.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1136/jmedgenet-2014-102697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503357PMC
January 2015

A weighted U-statistic for genetic association analyses of sequencing data.

Genet Epidemiol 2014 Dec 20;38(8):699-708. Epub 2014 Oct 20.

Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, United States of America; Department of Biostatistics and Epidemiology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America.

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http://dx.doi.org/10.1002/gepi.21864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236269PMC
December 2014

Mutational landscape of candidate genes in familial prostate cancer.

Prostate 2014 Oct 11;74(14):1371-8. Epub 2014 Aug 11.

Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1002/pros.22849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142071PMC
October 2014

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Mol Endocrinol 2014 Oct 22;28(10):1740-51. Epub 2014 Aug 22.

Division of Clinical Pharmacology (M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics; Departments of Oncology (J.N.I.) and Health Sciences Research (A.B., G.D.J., E.E.C., D.J.S.); and Division of Endocrinology (S.K.), Mayo Clinic, Rochester, Minnesota 55905; Massachusetts General Hospital (P.E.G.), Harvard University, Boston, Massachusetts 02114; Rikagaku Kenkyūsho Center for Integrative Medical Science (M.K., Y.F.), Yokohama, Japan 230-0045; School of Medicine (Y.N.), Chicago University, Chicago, Illinois 60637; National Cancer Institute of Canada Clinical Trials Group (J.-A.W.C., L.E.S.), Kingston, Ontario, Canada K7L 3N6; and Division of Oncology (M.J.E.), Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110.

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http://dx.doi.org/10.1210/me.2014-1147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179631PMC
October 2014

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Sonja I Berndt David V Conti Fredrick Schumacher Ying Han Sara Benlloch Dennis J Hazelett Zhaoming Wang Ed Saunders Daniel Leongamornlert Sara Lindstrom Sara Jugurnauth-Little Tokhir Dadaev Malgorzata Tymrakiewicz Daniel O Stram Kristin Rand Peggy Wan Alex Stram Xin Sheng Loreall C Pooler Karen Park Lucy Xia Jonathan Tyrer Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Merideth Yeager Laurie Burdette Charles C Chung Amy Hutchinson Kai Yu Chee Goh Mahbubl Ahmed Koveela Govindasami Michelle Guy Teuvo L J Tammela Anssi Auvinen Tiina Wahlfors Johanna Schleutker Tapio Visakorpi Katri A Leinonen Jianfeng Xu Markus Aly Jenny Donovan Ruth C Travis Tim J Key Afshan Siddiq Federico Canzian Kay-Tee Khaw Atsushi Takahashi Michiaki Kubo Paul Pharoah Nora Pashayan Maren Weischer Borge G Nordestgaard Sune F Nielsen Peter Klarskov Martin Andreas Røder Peter Iversen Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Janet L Stanford Suzanne Kolb Sarah Holt Beatrice Knudsen Antonio Hurtado Coll Susan M Gapstur W Ryan Diver Victoria L Stevens Christiane Maier Manuel Luedeke Kathleen Herkommer Antje E Rinckleb Sara S Strom Curtis Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Lisa Cannon-Albright Cezary Cybulski Dominika Wokołorczyk Wojciech Kluźniak Jong Park Thomas Sellers Hui-Yi Lin William B Isaacs Alan W Partin Hermann Brenner Aida Karina Dieffenbach Christa Stegmaier Constance Chen Edward L Giovannucci Jing Ma Meir Stampfer Kathryn L Penney Lorelei Mucci Esther M John Sue A Ingles Rick A Kittles Adam B Murphy Hardev Pandha Agnieszka Michael Andrzej M Kierzek William Blot Lisa B Signorello Wei Zheng Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Barbara Nemesure John Carpten Cristina Leske Suh-Yuh Wu Anselm Hennis Adam S Kibel Benjamin A Rybicki Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein S Lilly Zheng Jyotsna Batra Judith Clements Amanda Spurdle Manuel R Teixeira Paula Paulo Sofia Maia Chavdar Slavov Radka Kaneva Vanio Mitev John S Witte Graham Casey Elizabeth M Gillanders Daniella Seminara Elio Riboli Freddie C Hamdy Gerhard A Coetzee Qiyuan Li Matthew L Freedman David J Hunter Kenneth Muir Henrik Gronberg David E Neal Melissa Southey Graham G Giles Gianluca Severi Michael B Cook Hidewaki Nakagawa Fredrik Wiklund Peter Kraft Stephen J Chanock Brian E Henderson Douglas F Easton Rosalind A Eeles Christopher A Haiman

Nat Genet 2014 Oct 14;46(10):1103-9. Epub 2014 Sep 14.

1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [2] Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. [3].

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http://dx.doi.org/10.1038/ng.3094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383163PMC
October 2014

PedBLIMP: extending linear predictors to impute genotypes in pedigrees.

Genet Epidemiol 2014 Sep 12;38(6):531-41. Epub 2014 Jul 12.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1002/gepi.21838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127134PMC
September 2014

Prospective validation of HLA-DRB1*07:01 allele carriage as a predictive risk factor for lapatinib-induced liver injury.

J Clin Oncol 2014 Aug 31;32(22):2296-303. Epub 2014 Mar 31.

Daniel J. Schaid and Shannon K. McDonnell, Mayo Clinic, Rochester, MN; Colin F. Spraggs and Charles J. Cox, GlaxoSmithKline Research and Development, Stevenage, Hertfordshire; Joan Curran, GlaxoSmithKline Research and Development, London, United Kingdom; Laura R. Parham, GlaxoSmithKline Research and Development, Research Triangle Park, NC; Bent Ejlertsen, Rigshospitalet, Copenhagen, Denmark; Dianne M. Finkelstein and Paul E. Goss, Massachusetts General Hospital, Boston, MA; and Erica Rappold and Lon R. Cardon, GlaxoSmithKline Research and Development, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2013.52.9867DOI Listing
August 2014

Treatment outcomes of depression: the pharmacogenomic research network antidepressant medication pharmacogenomic study.

J Clin Psychopharmacol 2014 Jun;34(3):313-7

From the Departments of *Psychiatry and Psychology, and †Health Sciences Research, Mayo Clinic, Rochester, MN; ‡Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York Presbyterian-Allen Hospital, New York, NY; §US Department of Defense, Department of Behavioral Health, Heidelberg, Germany; ∥Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine University of Iowa Hospitals and Clinics, Iowa, IA; and Departments of ¶Information Technology, and #Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/JCP.0000000000000099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992481PMC
June 2014

Regularized rare variant enrichment analysis for case-control exome sequencing data.

Genet Epidemiol 2014 Feb 30;38(2):104-13. Epub 2013 Dec 30.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://dx.doi.org/10.1002/gepi.21783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985431PMC
February 2014

Detecting genomic clustering of risk variants from sequence data: cases versus controls.

Hum Genet 2013 Nov 11;132(11):1301-9. Epub 2013 Jul 11.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA,

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http://dx.doi.org/10.1007/s00439-013-1335-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797865PMC
November 2013

A kernel regression approach to gene-gene interaction detection for case-control studies.

Genet Epidemiol 2013 Nov 19;37(7):695-703. Epub 2013 Jul 19.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1002/gepi.21749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800261PMC
November 2013

Regression modeling of allele frequencies and testing Hardy Weinberg Equilibrium.

Hum Hered 2012 11;74(2):71-82. Epub 2013 Jan 11.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1159/000345846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708318PMC
September 2013

Multiple genetic variant association testing by collapsing and kernel methods with pedigree or population structured data.

Genet Epidemiol 2013 Jul 5;37(5):409-18. Epub 2013 May 5.

Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1002/gepi.21727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706099PMC
July 2013

A bivariate mann-whitney approach for unraveling genetic variants and interactions contributing to comorbidity.

Genet Epidemiol 2013 Apr 17;37(3):248-55. Epub 2013 Jan 17.

Department of Epidemiology and Biostatics, Michigan State University, East Lansing, Michigan, USA.

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http://doi.wiley.com/10.1002/gepi.21709
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http://dx.doi.org/10.1002/gepi.21709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760410PMC
April 2013

Two-phase designs to follow-up genome-wide association signals with DNA resequencing studies.

Genet Epidemiol 2013 Apr 24;37(3):229-38. Epub 2013 Jan 24.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/gepi.21708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740575PMC
April 2013

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Fredrick R Schumacher Fredrik Wiklund Sonja I Berndt Sara Benlloch Graham G Giles Gianluca Severi David E Neal Freddie C Hamdy Jenny L Donovan David J Hunter Brian E Henderson Michael J Thun Michael Gaziano Edward L Giovannucci Afshan Siddiq Ruth C Travis David G Cox Federico Canzian Elio Riboli Timothy J Key Gerald Andriole Demetrius Albanes Richard B Hayes Johanna Schleutker Anssi Auvinen Teuvo L J Tammela Maren Weischer Janet L Stanford Elaine A Ostrander Cezary Cybulski Jan Lubinski Stephen N Thibodeau Daniel J Schaid Karina D Sorensen Jyotsna Batra Judith A Clements Suzanne Chambers Joanne Aitken Robert A Gardiner Christiane Maier Walther Vogel Thilo Dörk Hermann Brenner Tomonori Habuchi Sue Ingles Esther M John Joanne L Dickinson Lisa Cannon-Albright Manuel R Teixeira Radka Kaneva Hong-Wei Zhang Yong-Jie Lu Jong Y Park Kathleen A Cooney Kenneth R Muir Daniel A Leongamornlert Edward Saunders Malgorzata Tymrakiewicz Nadiya Mahmud Michelle Guy Koveela Govindasami Lynne T O'Brien Rosemary A Wilkinson Amanda L Hall Emma J Sawyer Tokhir Dadaev Jonathan Morrison David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas Van As Christopher J Woodhouse Alan Thompson Tim Dudderidge Chris Ogden Colin S Cooper Artitaya Lophatonanon Melissa C Southey John L Hopper Dallas English Jarmo Virtamo Loic Le Marchand Daniele Campa Rudolf Kaaks Sara Lindstrom W Ryan Diver Susan Gapstur Meredith Yeager Angela Cox Mariana C Stern Roman Corral Markus Aly William Isaacs Jan Adolfsson Jianfeng Xu S Lilly Zheng Tiina Wahlfors Kimmo Taari Paula Kujala Peter Klarskov Børge G Nordestgaard M Andreas Røder Ruth Frikke-Schmidt Stig E Bojesen Liesel M FitzGerald Suzanne Kolb Erika M Kwon Danielle M Karyadi Torben Falck Orntoft Michael Borre Antje Rinckleb Manuel Luedeke Kathleen Herkommer Andreas Meyer Jürgen Serth James R Marthick Briony Patterson Dominika Wokolorczyk Amanda Spurdle Felicity Lose Shannon K McDonnell Amit D Joshi Ahva Shahabi Pedro Pinto Joana Santos Ana Ray Thomas A Sellers Hui-Yi Lin Robert A Stephenson Craig Teerlink Heiko Muller Dietrich Rothenbacher Norihiko Tsuchiya Shintaro Narita Guang-Wen Cao Chavdar Slavov Vanio Mitev Stephen Chanock Henrik Gronberg Christopher A Haiman Peter Kraft Douglas F Easton Rosalind A Eeles

Hum Mol Genet 2013 Jan 12;22(2):408-15. Epub 2012 Oct 12.

Strangeways Laboratory, Centre for Cancer Genetic Epidemiology, Worts Causeway, Cambridge CB1 8RN, UK.

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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/dds425
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http://dx.doi.org/10.1093/hmg/dds425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526158PMC
January 2013

Trees Assembling Mann-Whitney approach for detecting genome-wide joint association among low-marginal-effect loci.

Genet Epidemiol 2013 Jan 7;37(1):84-91. Epub 2012 Nov 7.

Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan 48824, USA.

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http://doi.wiley.com/10.1002/gepi.21693
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593719PMC
January 2013

Power of single- vs. multi-marker tests of association.

Genet Epidemiol 2012 Jul 30;36(5):480-7. Epub 2012 May 30.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106-7281, USA.

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http://dx.doi.org/10.1002/gepi.21642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708310PMC
July 2012

Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.

Breast Cancer Res 2012 Mar 9;14(2):R41. Epub 2012 Mar 9.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/bcr3137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446375PMC
March 2012

Using the gene ontology to scan multilevel gene sets for associations in genome wide association studies.

Genet Epidemiol 2012 Jan 7;36(1):3-16. Epub 2011 Dec 7.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310255PMC
January 2012

Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy.

Clin Cancer Res 2011 Sep 20;17(17):5801-11. Epub 2011 Jul 20.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167019PMC
September 2011

Two-stage case-control designs for rare genetic variants.

Hum Genet 2010 Jun 30;127(6):659-68. Epub 2010 Mar 30.

Division of Biomedical Statistics and Informatics, Harwick 7, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724230PMC
June 2010