Daniel J Renouf

Tumor infiltrating neutrophils and gland formation predict overall survival and molecular subgroups in pancreatic ductal adenocarcinoma.

Authors:

Julia R Naso James T Topham Joanna M Karasinska Michael K C Lee Steve E Kalloger Hui-Li Wong Jessica Nelson Richard A Moore Andrew J Mungall Steven J M Jones Janessa Laskin Marco A Marra Daniel J Renouf David F Schaeffer

Cancer Med 2020 Dec 28. Epub 2020 Dec 28.

Division of Anatomic Pathology, Vancouver General Hospital, Vancouver, BC, Canada.

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December 2020

Efficacy and Prognostic Factors for Y-90 Radioembolization (Y-90) in Metastatic Neuroendocrine Tumors with Liver Metastases.

Authors:

Erica S Tsang Jonathan M Loree Janine M Davies Sharlene Gill David Liu Stephen Ho Daniel J Renouf Howard J Lim Hagen F Kennecke

Can J Gastroenterol Hepatol 2020 23;2020:5104082. Epub 2020 Nov 23.

Floyd and Delores Jones Cancer Institute, Virginia Mason Cancer Institute, Seattle, WA, USA.

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November 2020

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer.

Authors:

Wells S Brown Paul C McDonald Oksana Nemirovsky Shannon Awrey Shawn C Chafe David F Schaeffer Jinyang Li Daniel J Renouf Ben Z Stanger Shoukat Dedhar

Cell Rep Med 2020 Nov 17;1(8):100131. Epub 2020 Nov 17.

Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.

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November 2020

Matching methods in precision oncology: An introduction and illustrative example.

Authors:

Deirdre Weymann Janessa Laskin Steven J M Jones Howard Lim Daniel J Renouf Robyn Roscoe Kasmintan A Schrader Sophie Sun Stephen Yip Marco A Marra Dean A Regier

Mol Genet Genomic Med 2020 Nov 25:e1554. Epub 2020 Nov 25.

Canadian Centre for Applied Research in Cancer Control, Cancer Control Research, BC Cancer, Vancouver, BC, Canada.

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November 2020

Uncovering Clinically Relevant Gene Fusions with Integrated Genomic and Transcriptomic Profiling of Metastatic Cancers.

Clin Cancer Res 2021 Jan 4;27(2):522-531. Epub 2020 Nov 4.

Department of Medical Oncology, BC Cancer, Vancouver, Canada.

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January 2021

Real-world treatment attrition rates in advanced esophagogastric cancer.

Authors:

Erica S Tsang Howard J Lim Daniel J Renouf Janine M Davies Jonathan M Loree Sharlene Gill

World J Gastroenterol 2020 Oct;26(39):6027-6036

Department of Medicine, BC Cancer, Vancouver V5Z 4E6, Canada.

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October 2020

Subtype-Discordant Pancreatic Ductal Adenocarcinoma Tumors Show Intermediate Clinical and Molecular Characteristics.

Clin Cancer Res 2021 Jan 13;27(1):150-157. Epub 2020 Oct 13.

Pancreas Centre BC, Vancouver, British Columbia, Canada.

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January 2021

Genome and Transcriptome Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors.

Clin Cancer Res 2021 Jan 5;27(1):202-212. Epub 2020 Oct 5.

Department of Medical Oncology, BC Cancer, Vancouver, British Columbia, Canada.

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January 2021

Delving into Early-onset Pancreatic Ductal Adenocarcinoma: How Does Age Fit In?

Clin Cancer Res 2021 Jan 21;27(1):246-254. Epub 2020 Sep 21.

BC Cancer, Vancouver, British Columbia, Canada.

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January 2021

Stroma vs epithelium-enhanced prognostics through histologic stratification in pancreatic ductal adenocarcinoma.

Authors:

Steve E Kalloger Joanna M Karasinska Martin S Keung Danielle L Thompson Julie Ho Christine Chow Dongxia Gao James T Topham Cassia Warren Hui-Li Wong Michael Kuan-Ching Lee Daniel J Renouf David F Schaeffer

Int J Cancer 2021 Jan 29;148(2):481-491. Epub 2020 Sep 29.

Pancreas Centre BC, Vancouver General Hospital, Vancouver, British Columbia, Canada.

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January 2021

Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma.

Gut 2020 Sep 15. Epub 2020 Sep 15.

Ontario Institute for Cancer Research, Toronto, Ontario, Canada

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September 2020

Eligibility for Second-line Therapy in Patients With Advanced Hepatocellular Carcinoma: A Population-based Study.

Authors:

Erica S Tsang Janine M Davies Jonathan M Loree Howard J Lim Daniel J Renouf Sharlene Gill

Am J Clin Oncol 2020 11;43(11):788-791

BC Cancer.

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November 2020

Therapeutic Potential of Afatinib in NRG1 Fusion-Driven Solid Tumors: A Case Series.

Authors:

Jacques Cadranel Stephen V Liu Michaël Duruisseaux Eva Branden Yasushi Goto Benjamin A Weinberg Christoph Heining Richard F Schlenk Parneet Cheema Martin R Jones Alexander Drilon Domenico Trombetta Lucia Anna Muscarella Khaled Tolba Valerie Gounant Agnieszka Cseh Flavio Solca Janessa J Laskin Daniel J Renouf

Oncologist 2021 Jan 23;26(1):7-16. Epub 2020 Sep 23.

University of British Columbia, BC Cancer, Vancouver, British Columbia, Canada.

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January 2021

Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer.

Authors:

Jolene Guenter Shirin Abadi Howard Lim Stephen Chia Ryan Woods Martin Jones Nevena Rebic Daniel J Renouf Janessa Laskin Marco Marra

J Oncol Pharm Pract 2020 Aug 26:1078155220951845. Epub 2020 Aug 26.

BC Cancer Agency, Vancouver, Canada.

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August 2020

Population-based Screening for in Metastatic Colorectal Cancer Reveals Increased Prevalence and Poor Prognosis.

Authors:

Jenny E Chu Benny Johnson Laveniya Kugathasan Van K Morris Kanwal Raghav Lucas Swanson Howard J Lim Daniel J Renouf Sharlene Gill Robert Wolber Aly Karsan Scott Kopetz David F Schaeffer Jonathan M Loree

Clin Cancer Res 2020 Sep 22;26(17):4599-4605. Epub 2020 Jun 22.

BC Cancer, Vancouver, British Columbia, Canada.

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September 2020

Endogenous Retrovirus Transcript Levels Are Associated with Immunogenic Signatures in Multiple Metastatic Cancer Types.

Mol Cancer Ther 2020 09 9;19(9):1889-1897. Epub 2020 Jun 9.

Pancreas Centre BC, Vancouver, British Columbia, Canada.

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September 2020

Burden of hereditary cancer susceptibility in unselected patients with pancreatic ductal adenocarcinoma referred for germline screening.

Cancer Med 2020 06 7;9(11):4004-4013. Epub 2020 Apr 7.

Hereditary Cancer Program, BC Cancer, part of Provincial Health Services Authority, Vancouver, BC, Canada.

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June 2020

A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors.

Authors:

Paul C McDonald Stephen Chia Philippe L Bedard Quincy Chu Michael Lyle Liren Tang Madhu Singh Zaihui Zhang Claudiu T Supuran Daniel J Renouf Shoukat Dedhar

Am J Clin Oncol 2020 07;43(7):484-490

BC Cancer.

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July 2020

Integration of Whole-Genome Sequencing With Circulating Tumor DNA Analysis Captures Clonal Evolution and Tumor Heterogeneity in Non-V600 BRAF Mutant Colorectal Cancer.

Authors:

Shehara Mendis Miguel Alcaide James T Topham Benny Johnson Ryan D Morin Jenny Chu Ian Bosdet Scott Kopetz Aly Karsan Sharlene Gill Janessa Laskin Steven J M Jones Marco A Marra David F Schaeffer Daniel J Renouf Jonathan M Loree

Clin Colorectal Cancer 2020 06 10;19(2):132-136.e3. Epub 2020 Feb 10.

Medical Oncology, BC Cancer, Vancouver, British Columbia, Canada. Electronic address:

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June 2020

Imatinib in combination with phosphoinositol kinase inhibitor buparlisib in patients with gastrointestinal stromal tumour who failed prior therapy with imatinib and sunitinib: a Phase 1b, multicentre study.

Authors:

Hans Gelderblom Robin L Jones Suzanne George Claudia Valverde Morales Charlotte Benson Jean-Yves Blay Daniel J Renouf Toshihiko Doi Axel Le Cesne Michael Leahy Sabine Hertle Paola Aimone Ulrike Brandt Patrick Schӧffski

Br J Cancer 2020 04 9;122(8):1158-1165. Epub 2020 Mar 9.

University Hospitals Leuven, Department of General Medical Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium.

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April 2020

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