Publications by authors named "Daniel Brewer"

54Publications

Author Correction: The evolutionary history of lethal metastatic prostate cancer.

Authors:
Gunes Gundem Peter Van Loo Barbara Kremeyer Ludmil B Alexandrov Jose M C Tubio Elli Papaemmanuil Daniel S Brewer Heini M L Kallio Gunilla Hägnäs Matti Annala Kati Kivinummi Victoria Goody Calli Latimer Sarah O'Meara Kevin J Dawson William Isaacs Michael R Emmert-Buck Matti Nykter Christopher Foster Zsofia Kote-Jarai Douglas Easton Hayley C Whitaker David E Neal Colin S Cooper Rosalind A Eeles Tapio Visakorpi Peter J Campbell Ultan McDermott David C Wedge G Steven Bova

Nature 2020 Aug;584(7820):E18

Institute of Biosciences and Medical Technology, BioMediTech, University of Tampere and Fimlab Laboratories, Tampere University Hospital, Tampere, FI-33520, Finland.

View Article and Find Full Text PDF
August 2020

Convergence of Prognostic Gene Signatures Suggests Underlying Mechanisms of Human Prostate Cancer Progression.

Authors:
Bogdan-Alexandru Luca Vincent Moulton Christopher Ellis Shea P Connell Daniel S Brewer Colin S Cooper

Genes (Basel) 2020 07 16;11(7). Epub 2020 Jul 16.

Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.

View Article and Find Full Text PDF
July 2020

A novel stratification framework for predicting outcome in patients with prostate cancer.

Authors:
Bogdan-Alexandru Luca Vincent Moulton Christopher Ellis Dylan R Edwards Colin Campbell Rosalin A Cooper Jeremy Clark Daniel S Brewer Colin S Cooper

Br J Cancer 2020 05 20;122(10):1467-1476. Epub 2020 Mar 20.

Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, Norfolk, UK.

View Article and Find Full Text PDF
May 2020

Development of a multivariable risk model integrating urinary cell DNA methylation and cell-free RNA data for the detection of significant prostate cancer.

Authors:
Shea P Connell Eve O'Reilly Alexandra Tuzova Martyn Webb Rachel Hurst Robert Mills Fang Zhao Bharati Bapat Colin S Cooper Antoinette S Perry Jeremy Clark Daniel S Brewer

Prostate 2020 05 9;80(7):547-558. Epub 2020 Mar 9.

Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.

View Article and Find Full Text PDF
May 2020

Potential for diagnosis of infectious disease from the 100,000 Genomes Project Metagenomic Dataset: Recommendations for reporting results.

Authors:
Gkikas Magiorkinis Philippa C Matthews Susan E Wallace Katie Jeffery Kevin Dunbar Richard Tedder Jean L Mbisa Bernadette Hannigan Effy Vayena Peter Simmonds Daniel S Brewer Abraham Gihawi Ghanasyam Rallapalli Lea Lahnstein Tom Fowler Christine Patch Fiona Maleady-Crowe Anneke Lucassen Colin Cooper

Wellcome Open Res 2019 14;4:155. Epub 2019 Oct 14.

University of East Anglia, Norwich, UK.

View Article and Find Full Text PDF
October 2019

The landscape of viral associations in human cancers.

Authors:
Marc Zapatka Ivan Borozan Daniel S Brewer Murat Iskar Adam Grundhoff Malik Alawi Nikita Desai Holger Sültmann Holger Moch Colin S Cooper Roland Eils Vincent Ferretti Peter Lichter

Nat Genet 2020 03 5;52(3):320-330. Epub 2020 Feb 5.

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

View Article and Find Full Text PDF
March 2020

Methodology for the at-home collection of urine samples for prostate cancer detection.

Authors:
Martyn Webb Kate Manley Mireia Olivan Ingrid Guldvik Malgorzata Palczynska Rachel Hurst Shea P Connell Ian G Mills Daniel S Brewer Robert Mills Colin S Cooper Jeremy Clark

Biotechniques 2020 02 29;68(2):65-71. Epub 2019 Nov 29.

Norwich Medical School, University of East Anglia, Norwich, UK.

View Article and Find Full Text PDF
February 2020

SEPATH: benchmarking the search for pathogens in human tissue whole genome sequence data leads to template pipelines.

Authors:
Abraham Gihawi Ghanasyam Rallapalli Rachel Hurst Colin S Cooper Richard M Leggett Daniel S Brewer

Genome Biol 2019 10 22;20(1):208. Epub 2019 Oct 22.

Norwich Medical School, University of East Anglia, Bob Champion Research and Education Building, Norwich, NR4 7UQ, UK.

View Article and Find Full Text PDF
October 2019

A Four-Group Urine Risk Classifier for Predicting Outcome in Prostate Cancer Patients.

Authors:
Shea P Connell Marcel Hanna Frank McCarthy Rachel Hurst Martyn Webb Helen Curley Helen Walker Rob Mills Richard Y Ball Martin G Sanda Kathryn L Pellegrini Dattatraya Patil Antoinette S Perry Jack Schalken Hardev Pandha Hayley Whitaker Nening Dennis Christine Stuttle Ian G Mills Ingrid Guldvik Chris Parker Daniel S Brewer Colin S Cooper Jeremy Clark

BJU Int 2019 May 20. Epub 2019 May 20.

Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.

View Article and Find Full Text PDF
May 2019

Transcriptome-Wide Effects of Sphingosine Kinases Knockdown in Metastatic Prostate and Breast Cancer Cells: Implications for Therapeutic Targeting.

Authors:
Heba Alshaker Qi Wang Daniel Brewer Dmitri Pchejetski

Front Pharmacol 2019 27;10:303. Epub 2019 Mar 27.

School of Medicine, University of East Anglia, Norwich, United Kingdom.

View Article and Find Full Text PDF
March 2019

epiCaPture: A Urine DNA Methylation Test for Early Detection of Aggressive Prostate Cancer.

Authors:
Eve O'Reilly Alexandra V Tuzova Anna L Walsh Niamh M Russell Odharnaith O'Brien Sarah Kelly Odharna Ni Dhomhnallain Liam DeBarra Connie M Dale Rick Brugman Gavin Clarke Olivia Schmidt Shane O'Meachair Dattatraya Patil Kathryn L Pellegrini Neil Fleshner Julia Garcia Fang Zhao Stephen Finn Robert Mills Marcelino Y Hanna Rachel Hurst Elizabeth McEvoy William M Gallagher Rustom P Manecksha Colin S Cooper Daniel S Brewer Bharati Bapat Martin G Sanda Jeremy Clark Antoinette S Perry

JCO Precis Oncol 2019 14;2019. Epub 2019 Jan 14.

University College Dublin.

View Article and Find Full Text PDF
January 2019

A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer.

Authors:
Fang Zhao Ekaterina Olkhov-Mitsel Shivani Kamdar Renu Jeyapala Julia Garcia Rachel Hurst Marcelino Yazbek Hanna Robert Mills Alexandra V Tuzova Eve O'Reilly Sarah Kelly Colin Cooper Daniel Brewer Antoinette S Perry Jeremy Clark Neil Fleshner Bharati Bapat

Clin Epigenetics 2018 11 23;10(1):147. Epub 2018 Nov 23.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.

View Article and Find Full Text PDF
November 2018

Von Hippel-Lindau with early onset of hemangioblastoma and multiple drop-metastases like spinal lesions: A case report.

Authors:
Thinh H Nguyen Teresia Pham Thea Strickland Daniel Brewer Muhittin Belirgen Mohamad M Al-Rahawan

Medicine (Baltimore) 2018 Sep;97(39):e12477

School of Medicine, Texas Tech University Health Science Center, Lubbock, TX.

View Article and Find Full Text PDF
September 2018

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Authors:
David C Wedge Gunes Gundem Thomas Mitchell Dan J Woodcock Inigo Martincorena Mohammed Ghori Jorge Zamora Adam Butler Hayley Whitaker Zsofia Kote-Jarai Ludmil B Alexandrov Peter Van Loo Charlie E Massie Stefan Dentro Anne Y Warren Clare Verrill Dan M Berney Nening Dennis Sue Merson Steve Hawkins William Howat Yong-Jie Lu Adam Lambert Jonathan Kay Barbara Kremeyer Katalin Karaszi Hayley Luxton Niedzica Camacho Luke Marsden Sandra Edwards Lucy Matthews Valeria Bo Daniel Leongamornlert Stuart McLaren Anthony Ng Yongwei Yu Hongwei Zhang Tokhir Dadaev Sarah Thomas Douglas F Easton Mahbubl Ahmed Elizabeth Bancroft Cyril Fisher Naomi Livni David Nicol Simon Tavaré Pelvender Gill Christopher Greenman Vincent Khoo Nicholas Van As Pardeep Kumar Christopher Ogden Declan Cahill Alan Thompson Erik Mayer Edward Rowe Tim Dudderidge Vincent Gnanapragasam Nimish C Shah Keiran Raine David Jones Andrew Menzies Lucy Stebbings Jon Teague Steven Hazell Cathy Corbishley Johann de Bono Gerhardt Attard William Isaacs Tapio Visakorpi Michael Fraser Paul C Boutros Robert G Bristow Paul Workman Chris Sander Freddie C Hamdy Andrew Futreal Ultan McDermott Bissan Al-Lazikani Andrew G Lynch G Steven Bova Christopher S Foster Daniel S Brewer David E Neal Colin S Cooper Rosalind A Eeles

Nat Genet 2018 05 16;50(5):682-692. Epub 2018 Apr 16.

The Institute of Cancer Research, London, UK.

View Article and Find Full Text PDF
May 2018

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.

Authors:
Niedzica Camacho Peter Van Loo Sandra Edwards Jonathan D Kay Lucy Matthews Kerstin Haase Jeremy Clark Nening Dennis Sarah Thomas Barbara Kremeyer Jorge Zamora Adam P Butler Gunes Gundem Sue Merson Hayley Luxton Steve Hawkins Mohammed Ghori Luke Marsden Adam Lambert Katalin Karaszi Gill Pelvender Charlie E Massie Zsofia Kote-Jarai Keiran Raine David Jones William J Howat Steven Hazell Naomi Livni Cyril Fisher Christopher Ogden Pardeep Kumar Alan Thompson David Nicol Erik Mayer Tim Dudderidge Yongwei Yu Hongwei Zhang Nimish C Shah Vincent J Gnanapragasam William Isaacs Tapio Visakorpi Freddie Hamdy Dan Berney Clare Verrill Anne Y Warren David C Wedge Andrew G Lynch Christopher S Foster Yong Jie Lu G Steven Bova Hayley C Whitaker Ultan McDermott David E Neal Rosalind Eeles Colin S Cooper Daniel S Brewer

PLoS Genet 2017 Sep 25;13(9):e1007001. Epub 2017 Sep 25.

Norwich Medical School, University of East Anglia, Norwich, Norfolk, United Kingdom.

View Article and Find Full Text PDF
September 2017

DESNT: A Poor Prognosis Category of Human Prostate Cancer.

Authors:
Bogdan-Alexandru Luca Daniel S Brewer Dylan R Edwards Sandra Edwards Hayley C Whitaker Sue Merson Nening Dennis Rosalin A Cooper Steven Hazell Anne Y Warren Rosalind Eeles Andy G Lynch Helen Ross-Adams Alastair D Lamb David E Neal Krishna Sethia Robert D Mills Richard Y Ball Helen Curley Jeremy Clark Vincent Moulton Colin S Cooper

Eur Urol Focus 2018 12 6;4(6):842-850. Epub 2017 Mar 6.

Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK. Electronic address:

View Article and Find Full Text PDF
December 2018

Prostate Single Nucleotide Polymorphism Provides a Crucial Clue to Cancer Aggression in Active Surveillance Patients.

Authors:
Colin S Cooper Jeremy Clark Daniel S Brewer Dylan R Edwards

Eur Urol 2016 Feb 9;69(2):229-30. Epub 2015 Oct 9.

School of Biological Sciences, University of East Anglia, Norwich, UK.

View Article and Find Full Text PDF
February 2016

Augmenting Predictive Modeling Tools with Clinical Insights for Care Coordination Program Design and Implementation.

Authors:
Tracy L Johnson Daniel Brewer Raymond Estacio Tara Vlasimsky Michael J Durfee Kathy R Thompson Rachel M Everhart Deborath J Rinehart Holly Batal

EGEMS (Wash DC) 2015 30;3(1):1181. Epub 2015 Jul 30.

Denver Health.

View Article and Find Full Text PDF
August 2015

For many patients who use large amounts of health care services, the need is intense yet temporary.

Authors:
Tracy L Johnson Deborah J Rinehart Josh Durfee Daniel Brewer Holly Batal Joshua Blum Carlos I Oronce Paul Melinkovich Patricia Gabow

Health Aff (Millwood) 2015 Aug;34(8):1312-9

Patricia Gabow is a professor of medicine at the University of Colorado School of Medicine and, now retired, was CEO at Denver Health.

View Article and Find Full Text PDF
August 2015

Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.

Authors:
Colin S Cooper Rosalind Eeles David C Wedge Peter Van Loo Gunes Gundem Ludmil B Alexandrov Barbara Kremeyer Adam Butler Andrew G Lynch Niedzica Camacho Charlie E Massie Jonathan Kay Hayley J Luxton Sandra Edwards Zsofia Kote-Jarai Nening Dennis Sue Merson Daniel Leongamornlert Jorge Zamora Cathy Corbishley Sarah Thomas Serena Nik-Zainal Manasa Ramakrishna Sarah O'Meara Lucy Matthews Jeremy Clark Rachel Hurst Richard Mithen Robert G Bristow Paul C Boutros Michael Fraser Susanna Cooke Keiran Raine David Jones Andrew Menzies Lucy Stebbings Jon Hinton Jon Teague Stuart McLaren Laura Mudie Claire Hardy Elizabeth Anderson Olivia Joseph Victoria Goody Ben Robinson Mark Maddison Stephen Gamble Christopher Greenman Dan Berney Steven Hazell Naomi Livni Cyril Fisher Christopher Ogden Pardeep Kumar Alan Thompson Christopher Woodhouse David Nicol Erik Mayer Tim Dudderidge Nimish C Shah Vincent Gnanapragasam Thierry Voet Peter Campbell Andrew Futreal Douglas Easton Anne Y Warren Christopher S Foster Michael R Stratton Hayley C Whitaker Ultan McDermott Daniel S Brewer David E Neal

Nat Genet 2015 Jun;47(6):689

View Article and Find Full Text PDF
June 2015