Daniel Baden

Daniel Baden

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Daniel Baden

Daniel Baden

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Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels.

Toxins (Basel) 2019 Sep 3;11(9). Epub 2019 Sep 3.

Department of Pharmacology, Box 357280, University of Washington, Seattle, WA 98195-7280, USA.

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http://dx.doi.org/10.3390/toxins11090513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784055PMC
September 2019

Training Public Health Advisors.

J Public Health Manag Pract 2015 Nov-Dec;21(6):E19-22

Field Services Office (Drs Meyer and Baden and Ms Brusuelas) and Public Health Associate Program (Ms Duncan), Office for State, Tribal, Local and Territorial Support, Centers for Disease Control and Prevention, Atlanta, Georgia.

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http://dx.doi.org/10.1097/PHH.0000000000000214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679716PMC
March 2017

Fluorescent Receptor Binding Assay for Detecting Ciguatoxins in Fish.

PLoS One 2016 13;11(4):e0153348. Epub 2016 Apr 13.

National Oceanic and Atmospheric Administration, Center for Coastal Fisheries and Habitat Research, Beaufort, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153348PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830512PMC
September 2016

Chemical analysis of Karenia papilionacea.

Toxicon 2015 Jul 15;101:85-91. Epub 2015 May 15.

University of North Carolina, Center of Marine Science, Wilmington, NC, 28409, USA. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2015.05.007DOI Listing
July 2015

Development of a fluorescence assay for the characterization of brevenal binding to rat brain synaptosomes.

J Nat Prod 2014 Sep 17;77(9):2014-20. Epub 2014 Sep 17.

Center for Marine Science, University of North Carolina at Wilmington , Wilmington, North Carolina 28409, United States.

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http://dx.doi.org/10.1021/np500118pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176390PMC
September 2014

Structure activity relationship of brevenal hydrazide derivatives.

Mar Drugs 2014 Mar 28;12(4):1839-58. Epub 2014 Mar 28.

Center for Marine Science, University of North Carolina Wilmington (UNCW), 5600 Marvin K. Moss Lane, Wilmington, NC 28409, USA.

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http://dx.doi.org/10.3390/md12041839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012454PMC
March 2014

Brevenal, a brevetoxin antagonist from Karenia brevis, binds to a previously unreported site on mammalian sodium channels.

Harmful Algae 2013 Jun;26:12-19

Center for Marine Science, University of North Carolina at Wilmington, 5600 Marvin K. Moss Lane, Wilmington, North Carolina 28409.

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http://dx.doi.org/10.1016/j.hal.2013.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684244PMC
June 2013

Bidirectional influence of sodium channel activation on NMDA receptor-dependent cerebrocortical neuron structural plasticity.

Proc Natl Acad Sci U S A 2012 Nov 12;109(48):19840-5. Epub 2012 Nov 12.

Department of Pharmacology, Creighton University School of Medicine, Omaha, NE 68178, USA.

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http://dx.doi.org/10.1073/pnas.1212584109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511701PMC
November 2012

Development of a competitive fluorescence-based synaptosome binding assay for brevetoxins.

Harmful Algae 2012 Sep;19:85-91

Center for Marine Science, University of North Carolina at Wilmington, 5600 Marvin K. Moss Lane, Wilmington, North Carolina 28409.

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http://dx.doi.org/10.1016/j.hal.2012.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440185PMC
September 2012

Repeated exposure to aerosolized brevetoxin-3 induces prolonged airway hyperresponsiveness and lung inflammation in sheep.

Inhal Toxicol 2011 Mar;23(4):205-11

University of Miami, Miller School of Medicine, Division of Comparative Pathology, Miami, Florida, 33140 USA.

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http://dx.doi.org/10.3109/08958378.2011.558936DOI Listing
March 2011

Brevetoxin inhalation alters the pulmonary response to influenza A in the male F344 rat.

J Toxicol Environ Health A 2011 ;74(5):313-24

Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA.

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http://dx.doi.org/10.1080/15287394.2010.519316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444170PMC
February 2011

Total synthesis of (-)-brevisin: a concise synthesis of a new marine polycyclic ether.

Org Lett 2011 Feb 19;13(4):696-9. Epub 2011 Jan 19.

Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1021/ol102925dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040829PMC
February 2011

Ciguatoxin-induced catecholamine secretion in bovine chromaffin cells: mechanism of action and reversible inhibition by brevenal.

Toxicon 2010 Oct 11;56(5):792-6. Epub 2009 Aug 11.

Queensland Brain Institute and School of Biomedical Sciences, The University of Queensland, St Lucia Campus, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.toxicon.2009.08.002DOI Listing
October 2010

Personal exposure to aerosolized red tide toxins (brevetoxins).

J Occup Environ Hyg 2010 Jun;7(6):326-31

Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA.

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http://dx.doi.org/10.1080/15459621003724041DOI Listing
June 2010

Absolute configuration of brevisamide and brevisin: confirmation of a universal biosynthetic process for Karenia brevis polyethers.

J Nat Prod 2010 Jun;73(6):1177-9

Center for Marine Science, University of North Carolina, Wilmington, 5600 Marvin K. Moss Lane, Wilmington, NC 28409, USA.

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http://dx.doi.org/10.1021/np100159jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925417PMC
June 2010

Characterization of Florida red tide aerosol and the temporal profile of aerosol concentration.

Toxicon 2010 May 29;55(5):922-9. Epub 2009 Oct 29.

Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA.

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http://dx.doi.org/10.1016/j.toxicon.2009.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837766PMC
May 2010

UV and solar TiO(2) photocatalysis of brevetoxins (PbTxs).

Toxicon 2010 May 24;55(5):1008-16. Epub 2009 Nov 24.

Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA.

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http://dx.doi.org/10.1016/j.toxicon.2009.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523301PMC
May 2010

Characterization of tamulamides A and B, polyethers isolated from the marine dinoflagellate Karenia brevis.

J Nat Prod 2010 Apr;73(4):536-40

Department of Oceanography, University of Washington, P.O. Box 357940, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1021/np900541wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881462PMC
April 2010

Characterization and localization of a hybrid non-ribosomal peptide synthetase and polyketide synthase gene from the toxic dinoflagellate Karenia brevis.

Mar Biotechnol (NY) 2010 Feb 27;12(1):32-41. Epub 2009 May 27.

Center for Marine Science, University of North Carolina Wilmington, 5600 Marvin K. Moss Lane, Wilmington, NC 28409, USA.

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http://dx.doi.org/10.1007/s10126-009-9197-yDOI Listing
February 2010

Exposure and effect assessment of aerosolized red tide toxins (brevetoxins) and asthma.

Environ Health Perspect 2009 Jul 13;117(7):1095-100. Epub 2009 Apr 13.

National Science Foundation National Institute of Environmental Health Sciences Oceans and Human Health Center, University of Miami Rosenstiel School of Marine and Atmospheric Sciences, Miami, Florida 33136, USA.

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http://isurus.mote.org/niehsredtidestudy/Exposure%20and%20Ef
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http://ehp.niehs.nih.gov/0900673
Publisher Site
http://dx.doi.org/10.1289/ehp.0900673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717136PMC
July 2009

Brevisin: an aberrant polycyclic ether structure from the dinoflagellate Karenia brevis and its implications for polyether assembly.

J Org Chem 2009 Feb;74(3):989-94

Center for Marine Science, University of North Carolina Wilmington, 5600 Marvin K. Moss Lane, Wilmington, North Carolina 28409, USA.

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http://dx.doi.org/10.1021/jo802183nDOI Listing
February 2009

Total synthesis and structural confirmation of brevisamide, a new marine cyclic ether alkaloid from the dinoflagellate Karenia brevis.

Org Lett 2009 Jan;11(1):217-20

Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1021/ol802426vDOI Listing
January 2009

Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neurons.

J Pharmacol Exp Ther 2008 Aug 30;326(2):604-13. Epub 2008 Apr 30.

Department of Pharmacology, Creighton University School of Medicine, Omaha, NE 68178, USA.

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http://dx.doi.org/10.1124/jpet.108.138230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852114PMC
August 2008

Brevisamide: an unprecedented monocyclic ether alkaloid from the dinoflagellate Karenia brevis that provides a potential model for ladder-frame initiation.

Org Lett 2008 Aug 23;10(16):3465-8. Epub 2008 Jul 23.

Center for Marine Science, University of North Carolina, Wilmington, 5600 Marvin K. Moss Lane, Wilmington, North Carolina 28409, USA.

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http://pubs.acs.org/doi/abs/10.1021/ol801243n
Publisher Site
http://dx.doi.org/10.1021/ol801243nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655204PMC
August 2008

Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways.

Brain Res 2007 Dec 4;1184:17-27. Epub 2007 Oct 4.

Creighton University, School of Medicine, Department of Pharmacology, Omaha, NE 68178, USA.

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http://dx.doi.org/10.1016/j.brainres.2007.09.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659874PMC
December 2007

Synthesis, modeling, and biological evaluation of analogues of the semisynthetic brevetoxin antagonist beta-naphthoyl-brevetoxin.

Chembiochem 2007 Dec;8(18):2233-9

Center for Marine Science, University of North Carolina Wilmington, 5600 Marvin. K. Moss Lane, Wilmington, NC 28409, USA.

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http://dx.doi.org/10.1002/cbic.200700317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613567PMC
December 2007

Aerosolized red-tide toxins (brevetoxins) and asthma.

Chest 2007 Jan;131(1):187-94

National Institute of Environmental Health Sciences Marine and Freshwater Biomedical Sciences Center, Rosenstiel School of Marine and Atmospheric Sciences, University of Miami, Miami, FL, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001236921549898
Publisher Site
http://dx.doi.org/10.1378/chest.06-1830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683400PMC
January 2007

Placental transport of brevetoxin-3 in CD-1 mice.

Toxicon 2006 Dec 18;48(8):1018-26. Epub 2006 Aug 18.

Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr. SE., Albuquerque NM 87108, USA.

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http://dx.doi.org/10.1016/j.toxicon.2006.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561222PMC
December 2006

Brevetoxin-induced neural insult in the retrosplenial cortex of mouse brain.

Inhal Toxicol 2006 Dec;18(14):1109-16

Department of Physiology and Pharmacology, University of Georgia Athens, Georgia, USA.

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http://dx.doi.org/10.1080/08958370600945804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613569PMC
December 2006

Total synthesis, structure revision, and absolute configuration of (-)-brevenal.

J Am Chem Soc 2006 Dec;128(51):16989-99

Laboratory of Biostructural Chemistry, Graduate School of Life Sciences, Tohoku University, Aoba-ku, Sendai 981-8555, Japan.

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http://dx.doi.org/10.1021/ja066772yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575246PMC
December 2006

Uptake, tissue distribution, and excretion of brevetoxin-3 administered to mice by intratracheal instillation.

J Toxicol Environ Health A 2006 Jul;69(14):1325-35

Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA.

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http://dx.doi.org/10.1080/15287390500360091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652734PMC
July 2006

Aerosolized Florida Red Tide Toxins and Human Health Effects.

Oceanography (Wash D C) 2006 Jun;19(2):107-109

Mount Sinai Medical Center and Professor of Medicine, Miller School of Medicine, University of Miami, Miami Beach, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081595PMC
http://dx.doi.org/10.5670/oceanog.2006.73DOI Listing
June 2006

The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes.

Arch Toxicol 2005 Nov 29;79(11):683-8. Epub 2005 Jun 29.

The Brody School of Medicine, East Carolina University, 600 Moye Blvd, Greenville, NC 27834, USA.

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http://dx.doi.org/10.1007/s00204-005-0676-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561221PMC
November 2005

Overview of aerosolized Florida red tide toxins: exposures and effects.

Environ Health Perspect 2005 May;113(5):618-20

National Institute of Environmental Health Sciences Marine and Freshwater Biomedical Sciences Center, University of Miami Rosenstiel School of Marine and Atmospheric Sciences, Miami, FL 33136, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257557PMC
http://dx.doi.org/10.1289/ehp.7501DOI Listing
May 2005

Natural and derivative brevetoxins: historical background, multiplicity, and effects.

Environ Health Perspect 2005 May;113(5):621-5

University of North Carolina at Wilmington, Center for Marine Science, 5600 Marvin Moss Lane, Wilmington, NC 28409, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257558PMC
http://dx.doi.org/10.1289/ehp.7499DOI Listing
May 2005

Effects of inhaled brevetoxins in allergic airways: toxin-allergen interactions and pharmacologic intervention.

Environ Health Perspect 2005 May;113(5):632-7

Division of Pulmonary and Critical Care Medicine, University of Miami at Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257560PMC
http://dx.doi.org/10.1289/ehp.7498DOI Listing
May 2005

Occupational exposure to aerosolized brevetoxins during Florida red tide events: effects on a healthy worker population.

Environ Health Perspect 2005 May;113(5):644-9

National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS F-46, Chamblee, GA 30341, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257562PMC
http://dx.doi.org/10.1289/ehp.7502DOI Listing
May 2005

Initial evaluation of the effects of aerosolized Florida red tide toxins (brevetoxins) in persons with asthma.

Environ Health Perspect 2005 May;113(5):650-7

National Institute of Environmental Health Sciences Marine and Freshwater Biomedical Sciences Center, University of Miami Rosenstiel School of Marine and Atmospheric Sciences, Miami, FL 33136, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257563PMC
http://dx.doi.org/10.1289/ehp.7500DOI Listing
May 2005

Airway responses to aerosolized brevetoxins in an animal model of asthma.

Am J Respir Crit Care Med 2005 Jan 24;171(1):26-34. Epub 2004 Sep 24.

Department of Research, Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140, USA.

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http://dx.doi.org/10.1164/rccm.200406-735OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650266PMC
January 2005

Brevetoxin augments NMDA receptor signaling in murine neocortical neurons.

Brain Res 2005 Jan;1031(1):30-8

College of Veterinary Medicine, Department of Physiology and Pharmacology, University of Georgia, Athens, GA 30602, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000689930401704
Publisher Site
http://dx.doi.org/10.1016/j.brainres.2004.10.018DOI Listing
January 2005

Characterization of Red Tide Aerosol on the Texas Coast.

Harmful Algae 2005 Jan;4(1):87-94

Lovelace Respiratory Research Institute, Albuquerque, NM, USA.

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http://dx.doi.org/10.1016/j.hal.2003.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845976PMC
January 2005

A new polyether ladder compound produced by the dinoflagellate Karenia brevis.

J Nat Prod 2005 Jan;68(1):2-6

Wilmington Center for Marine Science, University of North Carolina, 5600 Marvin K. Moss Lane, Wilmington, North Carolina 28409, USA.

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http://dx.doi.org/10.1021/np049797oDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659471PMC
January 2005

Brevenal is a natural inhibitor of brevetoxin action in sodium channel receptor binding assays.

Cell Mol Neurobiol 2004 Aug;24(4):553-63

Center for Marine Science, University of North Carolina at Wilmington, Wilmington, North Carolina 28409, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659878PMC
http://dx.doi.org/10.1023/b:cemn.0000023629.81595.09DOI Listing
August 2004

Brevetoxin activation of voltage-gated sodium channels regulates Ca dynamics and ERK1/2 phosphorylation in murine neocortical neurons.

J Neurochem 2004 May;89(3):739-49

University of Georgia, College of Veterinary Medicine, Department of Physiology and Pharmacology, Athens, Georgia, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02407.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650275PMC
May 2004

Brevetoxin Degradation and By-Product Formation via Natural Sunlight.

Harmful Algae 2002 (2002) 2004;10:153-154

Florida International University, Miami, FL 33199, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591915PMC
January 2004

Toxicogenomic effects of marine brevetoxins in liver and brain of mouse.

Comp Biochem Physiol B Biochem Mol Biol 2003 Oct;136(2):173-82

NIEHS Marine and Freshwater Biomedical Sciences Center, Rosenstiel School of Marine and Atmospheric Science, University of Miami, 4600 Rickenbacker Causeway, Miami, FL 33149, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663909PMC
http://dx.doi.org/10.1016/s1096-4959(03)00223-9DOI Listing
October 2003

The Utah rural residency study: a blueprint for evaluating potential sites for development of a 4-4-4 family practice residency program in a rural community.

J Rural Health 2003 ;19(2):190-8

Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City 84132, USA.

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http://dx.doi.org/10.1111/j.1748-0361.2003.tb00561.xDOI Listing
May 2003

New fish-killing alga in coastal Delaware produces neurotoxins.

Environ Health Perspect 2002 May;110(5):465-70

Center for Marine Science, University of North Carolina at Wilmington, Wilmington, North Carolina 28409, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240834PMC
http://dx.doi.org/10.1289/ehp.02110465DOI Listing
May 2002