Publications by authors named "Daniel B Lipka"

46Publications

Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction.

Authors:
Christoph Niemöller Julius Wehrle Julian Riba Rainer Claus Nathalie Renz Janika Rhein Sabine Bleul Juliane M Stosch Justus Duyster Christoph Plass Pavlo Lutsik Daniel B Lipka Michael Lübbert Heiko Becker

Commun Biol 2021 Feb 1;4(1):153. Epub 2021 Feb 1.

Department of Medicine I, Medical Center - University of Freiburg, Freiburg, Germany.

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February 2021

Robustness of convolutional neural networks in recognition of pigmented skin lesions.

Authors:
Roman C Maron Sarah Haggenmüller Christof von Kalle Jochen S Utikal Friedegund Meier Frank F Gellrich Axel Hauschild Lars E French Max Schlaak Kamran Ghoreschi Heinz Kutzner Markus V Heppt Sebastian Haferkamp Wiebke Sondermann Dirk Schadendorf Bastian Schilling Achim Hekler Eva Krieghoff-Henning Jakob N Kather Stefan Fröhling Daniel B Lipka Titus J Brinker

Eur J Cancer 2021 Jan 7;145:81-91. Epub 2021 Jan 7.

Digital Biomarkers for Oncology Group, National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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January 2021

Methrix: an R/bioconductor package for systematic aggregation and analysis of bisulfite sequencing data.

Authors:
Anand Mayakonda Maximilian Schönung Joschka Hey Rajbir Nath Batra Clarissa Feuerstein-Akgoz Kristin Köhler Daniel B Lipka Rocio Sotillo Christoph Plass Pavlo Lutsik Reka Toth

Bioinformatics 2020 Dec 21. Epub 2020 Dec 21.

Division of Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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December 2020

International Consensus Definition of DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia.

Authors:
Maximilian Schönung Julia Meyer Peter Nöllke Adam B Olshen Mark Hartmann Norihiro Murakami Manabu Wakamatsu Yusuke Okuno Christoph Plass Mignon L Loh Charlotte M Niemeyer Hideki Muramatsu Christian Flotho Elliot Stieglitz Daniel B Lipka

Clin Cancer Res 2021 Jan 2;27(1):158-168. Epub 2020 Nov 2.

Section Translational Cancer Epigenomics, Division Translational Medical Oncology, German Cancer Research Center (DKFZ) & National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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January 2021

AmpliconDesign - an interactive web server for the design of high-throughput targeted DNA methylation assays.

Authors:
Maximilian Schönung Jana Hess Pascal Bawidamann Sina Stäble Joschka Hey Jens Langstein Yassen Assenov Dieter Weichenhan Pavlo Lutsik Daniel B Lipka

Epigenetics 2020 Oct 24:1-7. Epub 2020 Oct 24.

Section Translational Cancer Epigenomics, Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) & National Center for Tumor Diseases (NCT) , Heidelberg, Germany.

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October 2020

Epigenomic technologies for precision oncology.

Authors:
Dieter Weichenhan Daniel B Lipka Pavlo Lutsik Ashish Goyal Christoph Plass

Semin Cancer Biol 2020 Aug 18. Epub 2020 Aug 18.

German Cancer Research Center Heidelberg, Cancer Epigenomics (B370), Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany. Electronic address:

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August 2020

Molecular tumor classification using DNA methylome analysis.

Authors:
Martin Sill Christoph Plass Stefan M Pfister Daniel B Lipka

Hum Mol Genet 2020 Oct;29(R2):R205-R213

Division of Translational Medical Oncology, Section Translational Cancer Epigenomics, German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT) Heidelberg, 69120 Heidelberg, Germany.

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October 2020

Germline SDHB-inactivating mutation in gastric spindle cell sarcoma.

Authors:
Christoph E Heilig Peter Horak Daniel B Lipka Andreas Mock Sebastian Uhrig Simon Kreutzfeldt Susan Richter Laura Gieldon Martina Fröhlich Barbara Hutter Daniel Hübschmann Veronica Teleanu Johann-Wilhelm Schmier Johannes Philipzen Bettina Beuthien-Baumann Evelin Schröck Andreas von Deimling Sebastian Bauer Christoph Heining Gunhild Mechtersheimer Albrecht Stenzinger Benedikt Brors Eva Wardelmann Hanno Glimm Wolfgang Hartmann Stefan Fröhling

Genes Chromosomes Cancer 2020 Oct 26;59(10):601-608. Epub 2020 Jun 26.

Department of Translational Medical Oncology, National Center for Tumor Diseases Heidelberg and German Cancer Research Center, Heidelberg, Germany.

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October 2020

Effects of Label Noise on Deep Learning-Based Skin Cancer Classification.

Authors:
Achim Hekler Jakob N Kather Eva Krieghoff-Henning Jochen S Utikal Friedegund Meier Frank F Gellrich Julius Upmeier Zu Belzen Lars French Justin G Schlager Kamran Ghoreschi Tabea Wilhelm Heinz Kutzner Carola Berking Markus V Heppt Sebastian Haferkamp Wiebke Sondermann Dirk Schadendorf Bastian Schilling Benjamin Izar Roman Maron Max Schmitt Stefan Fröhling Daniel B Lipka Titus J Brinker

Front Med (Lausanne) 2020 6;7:177. Epub 2020 May 6.

National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, Germany.

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May 2020

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.

Authors:
Justyna A Wierzbinska Reka Toth Naveed Ishaque Karsten Rippe Jan-Philipp Mallm Lara C Klett Daniel Mertens Thorsten Zenz Thomas Hielscher Marc Seifert Ralf Küppers Yassen Assenov Pavlo Lutsik Stephan Stilgenbauer Philipp M Roessner Martina Seiffert John Byrd Christopher C Oakes Christoph Plass Daniel B Lipka

Genome Med 2020 03 18;12(1):29. Epub 2020 Mar 18.

The German Cancer Consortium (DKTK), Heidelberg, Germany.

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March 2020

Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.

Authors:
Simon Schwörer Friedrich Becker Christian Feller Ali H Baig Ute Köber Henriette Henze Johann M Kraus Beibei Xin André Lechel Daniel B Lipka Christy S Varghese Manuel Schmidt Remo Rohs Ruedi Aebersold Kay L Medina Hans A Kestler Francesco Neri Julia von Maltzahn Stefan Tümpel K Lenhard Rudolph

Nature 2019 Aug;572(7769):E11-E15

Leibniz-Institute on Aging - Fritz Lipmann Institute (FLI), Beutenbergstrasse 11, 07745, Jena, Germany.

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August 2019

Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target.

Authors:
Elias Orouji Aniello Federico Lionel Larribère Daniel Novak Daniel B Lipka Yassen Assenov Sachindra Sachindra Laura Hüser Karol Granados Christoffer Gebhardt Christoph Plass Viktor Umansky Jochen Utikal

Int J Cancer 2019 12 9;145(12):3462-3477. Epub 2019 Jun 9.

German Cancer Research Center (DKFZ), Skin Cancer Unit, Heidelberg, Baden Württemberg, Germany.

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December 2019

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML.

Authors:
Swati Garg Armando Reyes-Palomares Lixiazi He Anne Bergeron Vincent-Philippe Lavallée Sébastien Lemieux Patrick Gendron Christian Rohde Jianglong Xia Prarabdha Jagdhane Carsten Müller-Tidow Daniel B Lipka Suzan Imren R Keith Humphries Claudia Waskow Binje Vick Irmela Jeremias Guillaume Richard-Carpentier Josée Hébert Guy Sauvageau Judith B Zaugg Frédéric Barabé Caroline Pabst

Blood 2019 07 10;134(3):263-276. Epub 2019 May 10.

Department of Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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July 2019

Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha.

Authors:
Claudia Schubert Manuel Allhoff Stefan Tillmann Tiago Maié Ivan G Costa Daniel B Lipka Mirle Schemionek Kristina Feldberg Julian Baumeister Tim H Brümmendorf Nicolas Chatain Steffen Koschmieder

J Hematol Oncol 2019 04 2;12(1):36. Epub 2019 Apr 2.

Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Pauwelsstr 30, 52074, Aachen, Germany.

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April 2019

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia.

Authors:
Christopher F Krombholz Lorena Gallego-Villar Sushree S Sahoo Pritam K Panda Marcin W Wlodarski Konrad Aumann Mark Hartmann Daniel B Lipka Michael Daskalakis Christoph Plass Charlotte M Niemeyer Miriam Erlacher Christian Flotho

Leukemia 2019 07 24;33(7):1805-1810. Epub 2019 Jan 24.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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July 2019

Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.

Authors:
Benjamin Goeppert Reka Toth Stephan Singer Thomas Albrecht Daniel B Lipka Pavlo Lutsik David Brocks Marion Baehr Oliver Muecke Yassen Assenov Lei Gu Volker Endris Albrecht Stenzinger Arianeb Mehrabi Peter Schirmacher Christoph Plass Dieter Weichenhan Stephanie Roessler

Hepatology 2019 05 28;69(5):2091-2106. Epub 2019 Feb 28.

Institute of Pathology, University Clinic of Heidelberg, Heidelberg, Germany.

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May 2019

From Basic Knowledge to Effective Therapies.

Authors:
Daniel B Lipka Pavlo Lutsik Christoph Plass

Cancer Cell 2018 12;34(6):871-873

Division of Cancer Epigenomics, German Cancer Research Center, Heidelberg, Germany; The German Cancer Research Consortium. Electronic address:

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December 2018

LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.

Authors:
Ani Grigoryan Novella Guidi Katharina Senger Thomas Liehr Karin Soller Gina Marka Angelika Vollmer Yolanda Markaki Heinrich Leonhardt Christian Buske Daniel B Lipka Christoph Plass Yi Zheng Medhanie A Mulaw Hartmut Geiger Maria Carolina Florian

Genome Biol 2018 11 7;19(1):189. Epub 2018 Nov 7.

Institute of Molecular Medicine and Stem Cell Aging, University of Ulm, Albert-Einstein-Allee 11c, 89081, Ulm, Germany.

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November 2018

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

Authors:
Daniel B Lipka Tania Witte Reka Toth Jing Yang Manuel Wiesenfarth Peter Nöllke Alexandra Fischer David Brocks Zuguang Gu Jeongbin Park Brigitte Strahm Marcin Wlodarski Ayami Yoshimi Rainer Claus Michael Lübbert Hauke Busch Melanie Boerries Mark Hartmann Maximilian Schönung Umut Kilik Jens Langstein Justyna A Wierzbinska Caroline Pabst Swati Garg Albert Catalá Barbara De Moerloose Michael Dworzak Henrik Hasle Franco Locatelli Riccardo Masetti Markus Schmugge Owen Smith Jan Stary Marek Ussowicz Marry M van den Heuvel-Eibrink Yassen Assenov Matthias Schlesner Charlotte Niemeyer Christian Flotho Christoph Plass

Nat Commun 2017 12 19;8(1):2126. Epub 2017 Dec 19.

Cancer Epigenetics Group, Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), INF 280, 69120, Heidelberg, Germany.

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December 2017

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

Authors:
Elliot Stieglitz Tali Mazor Adam B Olshen Huimin Geng Laura C Gelston Jon Akutagawa Daniel B Lipka Christoph Plass Christian Flotho Farid F Chehab Benjamin S Braun Joseph F Costello Mignon L Loh

Nat Commun 2017 12 19;8(1):2127. Epub 2017 Dec 19.

Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, 1450 3rd Street, San Francisco, CA, 94158, USA.

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December 2017