Daniel Alcolea

Daniel Alcolea

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Daniel Alcolea

Publications by authors named "Daniel Alcolea"

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APP-derived peptides reflect neurodegeneration in frontotemporal dementia.

Ann Clin Transl Neurol 2019 Dec 2. Epub 2019 Dec 2.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/acn3.50948DOI Listing
December 2019

Detection of amyloid beta peptides in body fluids for the diagnosis of alzheimer's disease: Where do we stand?

Crit Rev Clin Lab Sci 2019 Oct 29:1-15. Epub 2019 Oct 29.

INSERM U1183, Laboratoire de Biochimie-Protéomique Clinique, CHU de Montpellier, Université de Montpellier, Montpellier, France.

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http://dx.doi.org/10.1080/10408363.2019.1678011DOI Listing
October 2019

Agreement of amyloid PET and CSF biomarkers for Alzheimer's disease on Lumipulse.

Ann Clin Transl Neurol 2019 Sep 28;6(9):1815-1824. Epub 2019 Aug 28.

Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau (IIB Sant Pau), Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/acn3.50873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764494PMC
September 2019

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 Aug 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

Impact of CSF storage volume on the analysis of Alzheimer's disease biomarkers on an automated platform.

Clin Chim Acta 2019 Mar 20;490:98-101. Epub 2018 Dec 20.

Sant Pau Memory Unit, Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau, Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas, CIBERNED, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2018.12.021DOI Listing
March 2019

Elevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD.

J Neurol Neurosurg Psychiatry 2019 02 8;90(2):180-186. Epub 2018 Oct 8.

Sant Pau Memory Unit, Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-318993
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http://dx.doi.org/10.1136/jnnp-2018-318993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351153PMC
February 2019

Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study.

Lancet Neurol 2018 10 29;17(10):860-869. Epub 2018 Aug 29.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau-Biomedical Research Institute Sant Pau-Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.

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http://dx.doi.org/10.1016/S1474-4422(18)30285-0DOI Listing
October 2018

CSF sAPPβ, YKL-40, and NfL along the ALS-FTD spectrum.

Neurology 2018 10 5;91(17):e1619-e1628. Epub 2018 Oct 5.

From the Sant Pau Memory Unit, Department of Neurology, Biomedical Research Institute Sant Pau (I.I.-G., D.A., V.M., O.D.-I., L.M., M.B.S.-S., A.S., I.S., R.B., J.C., J.F., A.L.), and Neuromuscular Diseases Unit, Department of Neurology (N.d.L., J.T.-S., E.C.-V., R.R.-G.), Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED) (I.I.-G., D.A., V.M., O.D.-I., R.B., J.C., J.F., A.L.); and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) (N.d.L., J.T.-S., E.C.-V., R.R.-G.), Madrid, Spain.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006383DOI Listing
October 2018

Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer's Disease.

Front Neurosci 2018 7;12:609. Epub 2018 Sep 7.

Department of Molecular Neuropathology, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Madrid, Spain.

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http://dx.doi.org/10.3389/fnins.2018.00609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137321PMC
September 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Authors:
Niklas Mattsson Colin Groot Willemijn J Jansen Susan M Landau Victor L Villemagne Sebastiaan Engelborghs Mark M Mintun Alberto Lleo José Luis Molinuevo William J Jagust Giovanni B Frisoni Adrian Ivanoiu Gaël Chételat Catarina Resende de Oliveira Karen M Rodrigue Johannes Kornhuber Anders Wallin Aleksandra Klimkowicz-Mrowiec Ramesh Kandimalla Julius Popp Pauline P Aalten Dag Aarsland Daniel Alcolea Ina S Almdahl Inês Baldeiras Mark A van Buchem Enrica Cavedo Kewei Chen Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Kiran Dip Gill Olymbia Gkatzima Timo Grimmer Harald Hampel Sanna-Kaisa Herukka Peter Johannsen Koen van Laere Mony J de Leon Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Barbara Mroczko Arto Nordlund Sudesh Prabhakar Oliver Peters Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Frans R J Verhey Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Rik Vandenberghe David J Brooks Tormod Fladby Christopher C Rowe Alexander Drzezga Marcel M Verbeek Marie Sarazin David A Wolk Adam S Fleisher William E Klunk Duk L Na Pascual Sánchez-Juan Dong Young Lee Agneta Nordberg Magda Tsolaki Vincent Camus Juha O Rinne Anne M Fagan Henrik Zetterberg Kaj Blennow Gil D Rabinovici Oskar Hansson Bart N M van Berckel Wiesje M van der Flier Philip Scheltens Pieter Jelle Visser Rik Ossenkoppele

Alzheimers Dement 2018 07 28;14(7):913-924. Epub 2018 Mar 28.

Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.02.009DOI Listing
July 2018

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.

World J Biol Psychiatry 2018 06 27;19(4):244-328. Epub 2017 Oct 27.

a Department of Psychiatry and Psychotherapy , Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg , Erlangen , Germany.

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http://dx.doi.org/10.1080/15622975.2017.1375556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916324PMC
June 2018

Cerebral changes and disrupted gray matter cortical networks in asymptomatic older adults at risk for Alzheimer's disease.

Neurobiol Aging 2018 04 20;64:58-67. Epub 2017 Dec 20.

CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, Spain; Department of Neurology, Institut d'Investigacions Biomediques Sant Pau-Hospital Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.12.010DOI Listing
April 2018

Challenges associated with biomarker-based classification systems for Alzheimer's disease.

Alzheimers Dement (Amst) 2018 21;10:346-357. Epub 2018 Apr 21.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.dadm.2018.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114028PMC
April 2018

Cortical microstructural changes along the Alzheimer's disease continuum.

Alzheimers Dement 2018 03 31;14(3):340-351. Epub 2017 Oct 31.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.09.013DOI Listing
March 2018

Kidins220 Correlates with Tau in Alzheimer's Disease Brain and Cerebrospinal Fluid.

J Alzheimers Dis 2017 ;55(4):1327-1333

Instituto de Investigaciones Biomédicas "Alberto Sols", Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain.

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http://dx.doi.org/10.3233/JAD-160639DOI Listing
February 2018

Feasibility of Lumbar Puncture in the Study of Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in Subjects with Down Syndrome.

J Alzheimers Dis 2017 ;55(4):1489-1496

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-160827DOI Listing
February 2018

A Common Variant in the MC1R Gene (p.V92M) is associated with Alzheimer's Disease Risk.

J Alzheimers Dis 2017 ;56(3):1065-1074

Dermatology Department, Melanoma Unit, Hospital Clinic & IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-161113DOI Listing
February 2018

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Authors:
Willemijn J Jansen Rik Ossenkoppele Betty M Tijms Anne M Fagan Oskar Hansson William E Klunk Wiesje M van der Flier Victor L Villemagne Giovanni B Frisoni Adam S Fleisher Alberto Lleó Mark A Mintun Anders Wallin Sebastiaan Engelborghs Duk L Na Gäel Chételat José Luis Molinuevo Susan M Landau Niklas Mattsson Johannes Kornhuber Osama Sabri Christopher C Rowe Lucilla Parnetti Julius Popp Tormod Fladby William J Jagust Pauline Aalten Dong Young Lee Rik Vandenberghe Catarina Resende de Oliveira Elisabeth Kapaki Lutz Froelich Adrian Ivanoiu Tomasz Gabryelewicz Marcel M Verbeek Páscual Sanchez-Juan Helmut Hildebrandt Vincent Camus Marzena Zboch David J Brooks Alexander Drzezga Juha O Rinne Andrew Newberg Alexandre de Mendonça Marie Sarazin Gil D Rabinovici Karine Madsen Milica G Kramberger Agneta Nordberg Vincent Mok Barbara Mroczko David A Wolk Philipp T Meyer Magda Tsolaki Philip Scheltens Frans R J Verhey Pieter Jelle Visser Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kaj Blennow Mark A van Buchem Enrica Cavedo Kewei Chen Elena Chipi Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Olymbia Gkatzima Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Peter Johannsen Aleksandra Klimkowicz-Mrowiec Sebastian Köhler Norman Koglin Koen van Laere Mony de Leon Viviana Lisetti Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Arto Nordlund Gerald P Novak George P Paraskevas Gayan Perera Oliver Peters Inez H G B Ramakers Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Henrik Zetterberg

JAMA Psychiatry 2018 01;75(1):84-95

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786156PMC
January 2018

Weight loss in the healthy elderly might be a non-cognitive sign of preclinical Alzheimer's disease.

Oncotarget 2017 Dec 31;8(62):104706-104716. Epub 2017 Oct 31.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.18632/oncotarget.22218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739594PMC
December 2017

CSF microRNA Profiling in Alzheimer's Disease: a Screening and Validation Study.

Mol Neurobiol 2017 11 13;54(9):6647-6654. Epub 2016 Oct 13.

Alzheimer's disease and other cognitive disorders unit, Neurology Service, Hospital Clínic i Universitari-, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Villarroel 170, Barcelona, 08036, Spain.

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http://dx.doi.org/10.1007/s12035-016-0106-xDOI Listing
November 2017

Cerebral amyloid angiopathy in Down syndrome and sporadic and autosomal-dominant Alzheimer's disease.

Alzheimers Dement 2017 Nov 29;13(11):1251-1260. Epub 2017 Apr 29.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Barcelona Down Medical Center, Fundació Catalana de Síndrome de Down, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660938PMC
November 2017

Plasma miR-34a-5p and miR-545-3p as Early Biomarkers of Alzheimer's Disease: Potential and Limitations.

Mol Neurobiol 2017 09 8;54(7):5550-5562. Epub 2016 Sep 8.

Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, Spain.

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http://dx.doi.org/10.1007/s12035-016-0088-8DOI Listing
September 2017

The pitfalls of biomarker-based classification schemes.

Alzheimers Dement 2017 09 10;13(9):1072-1074. Epub 2017 Jul 10.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain; Barcelona Down Medical Center, Fundació Catalana de Síndrome de Down, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.06.002DOI Listing
September 2017

CSF sAPPβ, YKL-40, and neurofilament light in frontotemporal lobar degeneration.

Neurology 2017 Jul 7;89(2):178-188. Epub 2017 Jun 7.

From the Department of Neurology (D.A., E.V., M.S.-C., I.I.-G., R.B., J.C., J.F., A. Lleó), Institut d'Investigacions Biomèdiques Sant Pau-Hospital de Sant Pau, Universitat Autònoma de Barcelona; Alzheimer's Disease and Other Cognitive Disorders Unit (A. Lladó, R.S.-V., J.L.M.), Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi I Sunyer, Barcelona; Servicio de Neurología (G.G.-R.), Hospital Universitario Ramón y Cajal, Madrid; Parkinson's Disease and Movement Disorders Unit (Y.C., M.J.M.), Neurology Service, Institute of Clinical Neurosciences, Hospital Clínic/IDIBAPS and University of Barcelona; Unitat de Trastorns Cognitius (G.P.-R.), Hospital Santa Maria, Lleida; Unidad de Neurología Cognitiva (G.A.-F., A.N., A.G.-M.), Servicio de Neurología, Hospital Universitari Son Espases, Palma de Mallorca; and Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (D.A., E.V., M.S.-C., I.I.-G., R.B., J.C., Y.C., M.J.M., J.F., A. Lleó), Madrid, Spain.

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http://dx.doi.org/10.1212/WNL.0000000000004088DOI Listing
July 2017

Longitudinal brain structural changes in preclinical Alzheimer's disease.

Alzheimers Dement 2017 May 28;13(5):499-509. Epub 2016 Sep 28.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau- Biomedical Research Institute Sant Pau-Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, CIBERNED, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.08.010DOI Listing
May 2017

Cerebrospinal fluid mitochondrial DNA in the Alzheimer's disease continuum.

Neurobiol Aging 2017 05 22;53:192.e1-192.e4. Epub 2016 Dec 22.

Memory Unit, Department of Neurology, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.12.009DOI Listing
May 2017

Progranulin Protein Levels in Cerebrospinal Fluid in Primary Neurodegenerative Dementias.

J Alzheimers Dis 2016 ;50(2):539-46

Memory Unit, Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-150746DOI Listing
November 2016

Early Cerebellar Hypometabolism in Patients With Frontotemporal Dementia Carrying the C9orf72 Expansion.

Alzheimer Dis Assoc Disord 2015 Oct-Dec;29(4):353-6

*Memory Disorders Unit, Department of Neurology, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED) Departments of †Nuclear Medicine ‡Radiology, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau. Universitat Autònoma de Barcelona §Port d'Informació Científica, Institut de Física d'Altes Energies, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1097/WAD.0000000000000056DOI Listing
September 2016

Copy number variation analysis of the 17q21.31 region and its role in neurodegenerative diseases.

Am J Med Genet B Neuropsychiatr Genet 2016 Mar 9;171B(2):175-80. Epub 2015 Oct 9.

Memory Unit, Department of Neurology, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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http://dx.doi.org/10.1002/ajmg.b.32390DOI Listing
March 2016

Effect of REST on brain metabolism in the Alzheimer disease continuum.

Ann Neurol 2015 Oct 25;78(4):661-2. Epub 2015 Aug 25.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau - Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/ana.24484DOI Listing
October 2015

Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer disease.

Neurology 2015 Aug 15;85(7):626-33. Epub 2015 Jul 15.

From the Department of Neurology (D.A., R.B., J.C., M.C.-I., E.M.-R., J.F., A.L.), Institut d'Investigacions Biomèdiques Sant Pau, Hospital de Sant Pau, Universitat Autònoma de Barcelona; Fundación CITA-Alzhéimer Fundazioa (P.M.-L., A.I., M.E.-T., A.E., M.C.), San Sebastián; Servicio de Neurología (P.S.-J., E.R.-R., J.L.V.H.), Hospital Universitario Marqués de Valdecilla, Santander; Servicio de Neurología (J.O., D.S.R.) and Unidad de Medicina Experimental (M.C.G.), Hospital General Gregorio Marañón, Madrid; Unidad de Demencias (C.A., J.M.M.), Hospital Clínico Universitario Virgen de la Arrixaca, Murcia; Instituto de Salud Carlos III (M.C.), CIBERNED, Madrid; Fundación CIEN (J.O., M.C.), Fundación Reina Sofía, Madrid; and Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas, CIBERNED (The SIGNAL Study), Spain.

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http://dx.doi.org/10.1212/WNL.0000000000001859DOI Listing
August 2015

Relationship between cortical thickness and cerebrospinal fluid YKL-40 in predementia stages of Alzheimer's disease.

Neurobiol Aging 2015 Jun 9;36(6):2018-23. Epub 2015 Mar 9.

Department of Neurology, Institut d'Investigacions Biomèdiques Sant Pau-Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red en enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.03.001DOI Listing
June 2015

Relationship between β-Secretase, inflammation and core cerebrospinal fluid biomarkers for Alzheimer's disease.

J Alzheimers Dis 2014 ;42(1):157-67

Memory Unit, Department of Neurology, Inst. Investigacions Biomèdiques Sant Pau - Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red en enfermedades Neurodegenerativas, CIBERNED, Spain.

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http://dx.doi.org/10.3233/JAD-140240DOI Listing
May 2015

Cerebral amyloid angiopathy-related atraumatic convexal subarachnoid hemorrhage: an ARIA before the tsunami.

J Cereb Blood Flow Metab 2015 May 4;35(5):710-7. Epub 2015 Mar 4.

1] Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain [2] Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain.

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http://dx.doi.org/10.1038/jcbfm.2015.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420868PMC
May 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Authors:
Willemijn J Jansen Rik Ossenkoppele Dirk L Knol Betty M Tijms Philip Scheltens Frans R J Verhey Pieter Jelle Visser Pauline Aalten Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kristen Bibeau Kaj Blennow David J Brooks Mark A van Buchem Vincent Camus Enrica Cavedo Kewei Chen Gael Chetelat Ann D Cohen Alexander Drzezga Sebastiaan Engelborghs Anne M Fagan Tormod Fladby Adam S Fleisher Wiesje M van der Flier Lisa Ford Stefan Förster Juan Fortea Nadia Foskett Kristian S Frederiksen Yvonne Freund-Levi Giovanni B Frisoni Lutz Froelich Tomasz Gabryelewicz Kiran Dip Gill Olymbia Gkatzima Estrella Gómez-Tortosa Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Helmut Hildebrandt Lianna Ishihara Adrian Ivanoiu William J Jagust Peter Johannsen Ramesh Kandimalla Elisabeth Kapaki Aleksandra Klimkowicz-Mrowiec William E Klunk Sebastian Köhler Norman Koglin Johannes Kornhuber Milica G Kramberger Koen Van Laere Susan M Landau Dong Young Lee Mony de Leon Viviana Lisetti Alberto Lleó Karine Madsen Wolfgang Maier Jan Marcusson Niklas Mattsson Alexandre de Mendonça Olga Meulenbroek Philipp T Meyer Mark A Mintun Vincent Mok José Luis Molinuevo Hanne M Møllergård John C Morris Barbara Mroczko Stefan Van der Mussele Duk L Na Andrew Newberg Agneta Nordberg Arto Nordlund Gerald P Novak George P Paraskevas Lucilla Parnetti Gayan Perera Oliver Peters Julius Popp Sudesh Prabhakar Gil D Rabinovici Inez H G B Ramakers Lorena Rami Catarina Resende de Oliveira Juha O Rinne Karen M Rodrigue Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Christopher C Rowe Eckart Rüther Osama Sabri Páscual Sanchez-Juan Isabel Santana Marie Sarazin Johannes Schröder Christin Schütte Sang W Seo Femke Soetewey Hilkka Soininen Luiza Spiru Hanne Struyfs Charlotte E Teunissen Magda Tsolaki Rik Vandenberghe Marcel M Verbeek Victor L Villemagne Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Anders Wallin Åsa K Wallin Jens Wiltfang David A Wolk Marzena Zboch Henrik Zetterberg

JAMA 2015 May;313(19):1924-38

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden87UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jama.2015.4668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486209PMC
May 2015

Cerebrospinal fluid β-amyloid and phospho-tau biomarker interactions affecting brain structure in preclinical Alzheimer disease.

Ann Neurol 2014 Aug 13;76(2):223-30. Epub 2014 Jun 13.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau - Universitat Autònoma de Barcelona; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas - CIBERNED.

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http://dx.doi.org/10.1002/ana.24186DOI Listing
August 2014

Reply: To PMID 23794434.

Ann Neurol 2014 Mar 7;75(3):460-1. Epub 2014 Mar 7.

Neurobiology Unit, Instituto de Investigaciones Biomedicas de Barcelona, Consejo Superior de Investigaciones Cientificas, CSIC; Centro de Investigacion Biomedica en Red de Enfermedades Neurodegenerativas, CIBERNED.

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http://dx.doi.org/10.1002/ana.24106DOI Listing
March 2014

Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease.

Ann Neurol 2013 Nov 4;74(5):655-68. Epub 2013 Sep 4.

Neurobiology Unit, Instituto de Investigaciones Biomedicas de Barcelona, Consejo Superior de Investigaciones Cientificas, CSIC, Barcelona, Spain; Centro de Investigacion Biomedica en Red de Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain.

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http://dx.doi.org/10.1002/ana.23955DOI Listing
November 2013

Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia.

Am J Alzheimers Dis Other Demen 2013 Aug 21;28(5):469-76. Epub 2013 May 21.

Department of Neurology, Memory Disorders Unit, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Universitat AutŒnoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1177/1533317513488918DOI Listing
August 2013

Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease.

Acta Neuropathol 2013 Feb 6;125(2):201-13. Epub 2012 Dec 6.

Department of Neurology, Inst. Investigacions Biomediques, Hospital de Sant Pau, Universitat Autònoma de Barcelona, Sant Antoni María Claret, 167, 08025 Barcelona, Spain.

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http://dx.doi.org/10.1007/s00401-012-1062-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623032PMC
February 2013

Rapidly progressive dementia: experience in a tertiary care medical center.

Alzheimer Dis Assoc Disord 2012 Jul-Sep;26(3):267-71

Department of Neurology, Memory Disorders Unit, Hospital de la Santa Creu i Sant Pau, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain.

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http://dx.doi.org/10.1097/WAD.0b013e3182368ed4DOI Listing
January 2013

Expansion mutation in C9ORF72 does not influence plasma progranulin levels in frontotemporal dementia.

Neurobiol Aging 2012 Aug 11;33(8):1851.e17-9. Epub 2012 Apr 11.

Department of Neurology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.03.005DOI Listing
August 2012

Remote cerebral hematomas in patients treated with intravenous rt-PA.

J Neurol 2010 Jul 6;257(7):1062-6. Epub 2010 Feb 6.

Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, Barcelona, Spain.

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http://link.springer.com/10.1007/s00415-010-5462-2
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http://dx.doi.org/10.1007/s00415-010-5462-2DOI Listing
July 2010