Daniel A Rappolee

Daniel A Rappolee

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Daniel A Rappolee

Daniel A Rappolee

Publications by authors named "Daniel A Rappolee"

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Stress Forces First Lineage Differentiation of Mouse Embryonic Stem Cells; Validation of a High-Throughput Screen for Toxicant Stress.

Stem Cells Dev 2019 01 7;28(2):101-113. Epub 2019 Jan 7.

1 CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, Michigan.

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https://www.liebertpub.com/doi/10.1089/scd.2018.0157
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http://dx.doi.org/10.1089/scd.2018.0157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350416PMC
January 2019

Effects of Gravity, Microgravity or Microgravity Simulation on Early Mammalian Development.

Stem Cells Dev 2018 09 11;27(18):1230-1236. Epub 2018 Jun 11.

1 Department of Ob/Gyn, Reproductive Endocrinology and Infertility, CS Mott Center for Human Growth and Development, Wayne State University School of Medicine , Detroit, Michigan.

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http://dx.doi.org/10.1089/scd.2018.0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157341PMC
September 2018

Why AMPK agonists not known to be stressors may surprisingly contribute to miscarriage or hinder IVF/ART.

J Assist Reprod Genet 2018 Aug 7;35(8):1359-1366. Epub 2018 Jun 7.

CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI, 48201, USA.

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http://dx.doi.org/10.1007/s10815-018-1213-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086802PMC
August 2018

Two-cell embryos are more sensitive than blastocysts to AMPK-dependent suppression of anabolism and stemness by commonly used fertility drugs, a diet supplement, and stress.

J Assist Reprod Genet 2017 Dec 15;34(12):1609-1617. Epub 2017 Sep 15.

CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI, 48201, USA.

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http://dx.doi.org/10.1007/s10815-017-1028-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714821PMC
December 2017

Using stem cell oxygen physiology to optimize blastocyst culture while minimizing hypoxic stress.

J Assist Reprod Genet 2017 10 24;34(10):1251-1259. Epub 2017 Jun 24.

CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI, 48201, USA.

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http://dx.doi.org/10.1007/s10815-017-0971-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633568PMC
October 2017

Hypoxic Stress Forces Adaptive and Maladaptive Placental Stress Responses in Early Pregnancy.

Birth Defects Res 2017 Oct;109(17):1330-1344

CS Mott Center for Human Growth and Development, Department of Obstetrics & Gynecology, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, Michigan.

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http://dx.doi.org/10.1002/bdr2.1149DOI Listing
October 2017

Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4.

Biol Reprod 2016 11 28;95(5):110. Epub 2016 Sep 28.

CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, Michigan

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http://dx.doi.org/10.1095/biolreprod.116.138412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178149PMC
November 2016

Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos.

J Assist Reprod Genet 2016 Aug 26;33(8):1027-39. Epub 2016 May 26.

CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI, 48201, USA.

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http://dx.doi.org/10.1007/s10815-016-0735-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974229PMC
August 2016

Direct reprogramming to multipotent trophoblast stem cells, and is pluripotency needed for regenerative medicine either?

Stem Cell Investig 2016 21;3:24. Epub 2016 Jun 21.

1 CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, 2 Department of Physiology, 3 Department of Pediatrics and Children's Hospital of Michigan, 4 Institutes for Environmental Health Science, Wayne State University School of Medicine, Detroit, MI 48201, USA ; 5 Department of Biology, University of Windsor, Windsor, ON N9B 3P4, Canada.

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http://sci.amegroups.com/article/view/10765/11376
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http://dx.doi.org/10.21037/sci.2016.06.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958061PMC
August 2016

Comparison of 2, 5, and 20 % O2 on the development of post-thaw human embryos.

J Assist Reprod Genet 2016 Jul 23;33(7):919-27. Epub 2016 Mar 23.

Center for Reproductive Medicine, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.

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http://dx.doi.org/10.1007/s10815-016-0693-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930774PMC
July 2016

Development and Validation of a Rex1-RFP Potency Activity Reporter Assay That Quantifies Stress-Forced Potency Loss in Mouse Embryonic Stem Cells.

Stem Cells Dev 2016 Feb 29;25(4):320-8. Epub 2016 Jan 29.

1 Department of Ob/Gyn, Reproductive Endocrinology and Infertility, CS Mott Center for Human Growth and Development, Wayne State University School of Medicine , Detroit, Michigan.

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http://dx.doi.org/10.1089/scd.2015.0169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761856PMC
February 2016

Molecular biology of the stress response in the early embryo and its stem cells.

Adv Exp Med Biol 2015 ;843:77-128

Department of Ob/Gyn, REI Division, Wayne State University School of Medicine, Detroit, MI, USA.

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http://dx.doi.org/10.1007/978-1-4939-2480-6_4DOI Listing
October 2015

Stress-induced enzyme activation primes murine embryonic stem cells to differentiate toward the first extraembryonic lineage.

Stem Cells Dev 2014 Dec;23(24):3049-64

1 Department of Obstetrics and Gynecology, Reproductive Endocrinology and Infertility, CS Mott Center for Human Growth and Development, Wayne State University School of Medicine , Detroit, Michigan.

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http://dx.doi.org/10.1089/scd.2014.0157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267551PMC
December 2014

Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency.

Stem Cell Res 2014 Nov 30;13(3 Pt A):478-91. Epub 2014 Jul 30.

CS Mott Center for Human Growth and Development, Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI 48201, USA; Program for Reproductive Sciences, Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201, USA; Karmanos Cancer Institute, Wayne State University School of Medicine, USA; Institutes for Environmental Health Science, Wayne State University School of Medicine, USA; Department of Biology, University of Windsor, Windsor, ON N9B 3P4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2014.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253717PMC
November 2014

When stresses collide.

Biol Reprod 2013 Sep 27;89(3):74. Epub 2013 Sep 27.

CS Mott Center for Human Growth and Development of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan.

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http://dx.doi.org/10.1095/biolreprod.113.113084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094198PMC
September 2013

Stress induces AMPK-dependent loss of potency factors Id2 and Cdx2 in early embryos and stem cells [corrected].

Stem Cells Dev 2013 May 11;22(10):1564-75. Epub 2013 Mar 11.

Department of Obstetrics and Gynecology, C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1089/scd.2012.0352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653377PMC
May 2013

Adaptive and Pathogenic Responses to Stress by Stem Cells during Development.

Cells 2012 Dec 10;1(4):1197-224. Epub 2012 Dec 10.

Department of Ob/Gyn, Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit MI, 48201, USA.

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http://dx.doi.org/10.3390/cells1041197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901130PMC
December 2012

Toxic stress prioritizes and imbalances stem cell differentiation: implications for new biomarkers and in vitro toxicology tests.

Syst Biol Reprod Med 2012 Feb;58(1):33-40

CS Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.3109/19396368.2011.647381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278038PMC
February 2012

Benzopyrene and experimental stressors cause compensatory differentiation in placental trophoblast stem cells.

Syst Biol Reprod Med 2010 Apr;56(2):168-83

C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI 48201, USA.

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http://dx.doi.org/10.3109/19396360903431638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836214PMC
April 2010

A major effect of simulated microgravity on several stages of preimplantation mouse development is lethality associated with elevated phosphorylated SAPK/JNK.

Reprod Sci 2009 Oct 22;16(10):947-59. Epub 2009 Jun 22.

Department of Obstetrics and Gynecology, C. S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

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http://dx.doi.org/10.1177/1933719109337544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858323PMC
October 2009

Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells.

Mol Reprod Dev 2005 May;71(1):1-11

CS Mott Center for Human Growth and Development of Ob/Gyn, Wayne State University School of Medicine, East Hancock, Detroit, Michigan 48201, USA.

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http://dx.doi.org/10.1002/mrd.20116DOI Listing
May 2005

Increases in phosphorylation of SAPK/JNK and p38MAPK correlate negatively with mouse embryo development after culture in different media.

Fertil Steril 2005 Apr;83 Suppl 1:1144-54

C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Hutzel Hospital, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI 48201, USA.

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http://dx.doi.org/10.1016/j.fertnstert.2004.08.038DOI Listing
April 2005

Acquisition of essential somatic cell cycle regulatory protein expression and implied activity occurs at the second to third cell division in mouse preimplantation embryos.

FEBS Lett 2005 Jan;579(2):398-408

CS Mott Center for Human Growth and Development of Ob/Gyn, Wayne State University School of Medicine, 275 East Hancock, Detroit, MI 48201, USA.

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http://doi.wiley.com/10.1016/j.febslet.2004.10.109
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http://dx.doi.org/10.1016/j.febslet.2004.10.109DOI Listing
January 2005

Serine-threonine kinases and transcription factors active in signal transduction are detected at high levels of phosphorylation during mitosis in preimplantation embryos and trophoblast stem cells.

Reproduction 2004 Nov;128(5):643-54

C S Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Hutzel Hospital, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

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http://dx.doi.org/10.1530/rep.1.00264DOI Listing
November 2004

Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos.

Dev Dyn 2004 Sep;231(1):72-87

C.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Hützel Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA.

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http://dx.doi.org/10.1002/dvdy.20114DOI Listing
September 2004