Publications by authors named "Dan Mercola"

55Publications

Transcriptional Profiling of Age-Associated Gene Expression Changes in Human Circulatory CD1c+ Myeloid Dendritic Cell Subset.

J Gerontol A Biol Sci Med Sci 2019 01;74(1):9-15

Division of Basic and Clinical Immunology, Department of Medicine, University of California, Irvine.

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http://dx.doi.org/10.1093/gerona/gly106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298184PMC
January 2019

When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow?

Curr Pharmacol Rep 2015 Dec 14;1(6):420-433. Epub 2015 Apr 14.

Department of Urology, University of California, Irvine, Orange, CA 92868, USA; Department of Pharmacology, University of California, Irvine, Orange, CA 92868, USA; Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, CA 92868, USA.

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http://dx.doi.org/10.1007/s40495-015-0039-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705552PMC
December 2015

Wnt signaling in castration-resistant prostate cancer: implications for therapy.

Am J Clin Exp Urol 2014 Apr;2(1):27-44

Department of Urology, University of California, Irvine, Orange, CA 92868, USA ; Department of Pharmaceutical Sciences, University of California, Irvine, Orange, CA 92868, USA ; Department of Pharmacology, University of California, Irvine, Orange, CA 92868, USA ; Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, CA 92868, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219296PMC
April 2014

Role of the adjacent stroma cells in prostate cancer development and progression: synergy between TGF-β and IGF signaling.

Biomed Res Int 2014 25;2014:502093. Epub 2014 Jun 25.

Department of Pathology and Laboratory Medicine, University of California at Irvine, Medical Surgery Building I, Room 168, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1155/2014/502093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095744PMC
October 2015

A gradient boosting algorithm for survival analysis via direct optimization of concordance index.

Comput Math Methods Med 2013 20;2013:873595. Epub 2013 Nov 20.

Department of Computer Science, University of California Irvine, Irvine, CA 92697, USA ; Institute for Genomics and Bioinformatics, University of California Irvine, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1155/2013/873595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853154PMC
August 2014

Natural products and transforming growth factor-beta (TGF-β) signaling in cancer development and progression.

Curr Cancer Drug Targets 2013 Jun;13(5):500-5

Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.2174/15680096113139990034DOI Listing
June 2013

Early growth response 3 (Egr3) is highly over-expressed in non-relapsing prostate cancer but not in relapsing prostate cancer.

PLoS One 2013 14;8(1):e54096. Epub 2013 Jan 14.

Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054096PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544741PMC
August 2013

Expression changes in the stroma of prostate cancer predict subsequent relapse.

PLoS One 2012 1;7(8):e41371. Epub 2012 Aug 1.

Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041371PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411675PMC
February 2013

TGF-β mediated DNA methylation in prostate cancer.

Transl Androl Urol 2012 Jun;1(2):78-88

The Department of Pathology and Laboratory Medicine, the University of California at Irvine, CA 92697, USA.

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http://dx.doi.org/10.3978/j.issn.2223-4683.2012.05.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131550PMC
June 2012

Expression of HER2 in Breast Cancer Promotes a Massive Reorganization of Gene Activity and Suggests a Role for Epigenetic Regulation.

J Data Mining Genomics Proteomics 2012 ;3

Department of Pathology & Laboratory Medicine, University of California, Irvine; Irvine, CA92697, USA.

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http://dx.doi.org/10.4172/2153-0602.1000e102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760961PMC
January 2012

Prostate cancer postoperative nomogram scores and obesity.

PLoS One 2011 Feb 24;6(2):e17382. Epub 2011 Feb 24.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017382PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044730PMC
February 2011

In silico estimates of tissue components in surgical samples based on expression profiling data.

Cancer Res 2010 Aug 27;70(16):6448-55. Epub 2010 Jul 27.

Department of Pathology and Laboratory Medicine, Vaccine Research Institute of San Diego, University of California, Irvine, Irvine, California 92067, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411177PMC
August 2010

PTEN regulation by Akt-EGR1-ARF-PTEN axis.

EMBO J 2009 Jan 4;28(1):21-33. Epub 2008 Dec 4.

The Burnham Institute for Medical Research, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1038/emboj.2008.238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633077PMC
January 2009

The wisdom of the commons: ensemble tree classifiers for prostate cancer prognosis.

Bioinformatics 2009 Jan 15;25(1):54-60. Epub 2008 Jul 15.

The Scripps Research Institute, La Jolla, San Diego, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btn354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638928PMC
January 2009

Claudin-1 immunohistochemistry for distinguishing malignant from benign epithelial lesions of prostate.

Prostate 2007 Jun;67(9):907-10

Burnham Institute for Medical Research, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1002/pros.20578DOI Listing
June 2007

Messenger RNAs under differential translational control in Ki-ras-transformed cells.

Mol Cancer Res 2006 Jan;4(1):47-60

Sidney Kimmel Cancer Center, San Diego, CA, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-04-0187DOI Listing
January 2006

Survey of differentially methylated promoters in prostate cancer cell lines.

Neoplasia 2005 Aug;7(8):748-60

Sidney Kimmel Cancer Center, 10835 Road to the Cure, San Diego, CA 92121, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501885PMC
http://dx.doi.org/10.1593/neo.05289DOI Listing
August 2005

Essential role of p38gamma in K-Ras transformation independent of phosphorylation.

J Biol Chem 2005 Jun 25;280(25):23910-7. Epub 2005 Apr 25.

Department of Radiation Oncology, Loyola University of Chicago, Maywood, Illinois 60153, USA.

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http://dx.doi.org/10.1074/jbc.M500699200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224721PMC
June 2005

From mRNA to tumor suppressor.

Nat Genet 2004 Sep;36(9):937-8

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http://dx.doi.org/10.1038/ng0904-937DOI Listing
September 2004

Antisense to the early growth response-1 gene (Egr-1) inhibits prostate tumor development in TRAMP mice.

Ann N Y Acad Sci 2003 Dec;1002:197-216

Sidney Kimmel Cancer Center, San Diego, California 92121, USA.

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http://dx.doi.org/10.1196/annals.1281.024DOI Listing
December 2003

In silico dissection of cell-type-associated patterns of gene expression in prostate cancer.

Proc Natl Acad Sci U S A 2004 Jan;101(2):615-20

Veterans Affairs San Diego Healthcare System, and Department of Medicine and John and Rebecca Moores UCSD Cancer Center, University of California at San Diego, La Jolla, USA.

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http://dx.doi.org/10.1073/pnas.2536479100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327196PMC
January 2004

Egr1 signaling in prostate cancer.

Cancer Biol Ther 2003 Nov-Dec;2(6):617-22

The Burnham Institute, Cancer Research Center, La Jolla, California 92037, USA.

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September 2004

Inhibition of Egr-1 expression reverses transformation of prostate cancer cells in vitro and in vivo.

Oncogene 2003 Jul;22(27):4194-204

Sidney Kimmel Cancer Center, 10835 Altman Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1038/sj.onc.1206560DOI Listing
July 2003

The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair.

J Biol Chem 2003 Jun 27;278(23):20582-92. Epub 2003 Mar 27.

Department of Cancer Gene Therapy, Sidney Kimmel Cancer Center, San Diego, California 92121, USA.

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http://dx.doi.org/10.1074/jbc.M210992200DOI Listing
June 2003

Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence.

Proc Natl Acad Sci U S A 2003 Mar 10;100(6):3233-8. Epub 2003 Mar 10.

Sidney Kimmel Cancer Center, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1073/pnas.2628034100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152275PMC
March 2003

In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1.

J Biol Chem 2003 Apr 31;278(16):14306-12. Epub 2003 Jan 31.

Burnham Institute, La Jolla Cancer Research Center, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M210502200DOI Listing
April 2003

Egr1 promotes growth and survival of prostate cancer cells. Identification of novel Egr1 target genes.

J Biol Chem 2003 Apr 29;278(14):11802-10. Epub 2003 Jan 29.

Burnham Institute, La Jolla Cancer Research Center, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M210279200DOI Listing
April 2003

C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma.

Clin Cancer Res 2003 Jan;9(1):391-401

Sidney Kimmel Cancer Center, San Diego, California 92121, USA.

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January 2003

Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival.

Tumour Biol 2002 Mar-Apr;23(2):93-102

Burnham Institute, La Jolla, Calif, USA.

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http://dx.doi.org/10.1159/000059711DOI Listing
August 2002