Publications by authors named "Dan L Nicolae"

95Publications

Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Nat Commun 2019 Sep 4;10(1):4082. Epub 2019 Sep 4.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1038/s41467-019-12158-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726619PMC
September 2019

Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

Lancet Respir Med 2019 06 27;7(6):509-522. Epub 2019 Apr 27.

Department of Medicine, The University of Chicago, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(19)30055-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534440PMC
June 2019

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Nat Commun 2019 02 20;10(1):880. Epub 2019 Feb 20.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1038/s41467-019-08469-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382865PMC
February 2019

Integrating predicted transcriptome from multiple tissues improves association detection.

PLoS Genet 2019 01 22;15(1):e1007889. Epub 2019 Jan 22.

Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358100PMC
January 2019

Parent of origin gene expression in a founder population identifies two new candidate imprinted genes at known imprinted regions.

PLoS One 2018 11;13(9):e0203906. Epub 2018 Sep 11.

Committee on Genetics, Genomics & Systems Biology, University of Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203906PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133383PMC
March 2019

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.

J Allergy Clin Immunol 2019 03 7;143(3):957-969. Epub 2018 Sep 7.

Program in Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco, San Francisco, Calif; Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, San Francisco, Calif; Department of Medicine, University of California, San Francisco, San Francisco, Calif.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183127
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http://dx.doi.org/10.1016/j.jaci.2016.08.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927816PMC
March 2019

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0197-6DOI Listing
September 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0157-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068780PMC
August 2018

Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus.

J Allergy Clin Immunol 2018 06 31;141(6):2282-2286.e6. Epub 2018 Jan 31.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; Pulmonary Genetics Center and Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2017.11.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994185PMC
June 2018

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.

Proc Natl Acad Sci U S A 2018 01 26;115(2):379-384. Epub 2017 Dec 26.

South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville and Edinburg, TX 78520.

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http://dx.doi.org/10.1073/pnas.1705859115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777025PMC
January 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Rare non-coding variants are associated with plasma lipid traits in a founder population.

Sci Rep 2017 11 27;7(1):16415. Epub 2017 Nov 27.

Department of Human Genetics, University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1038/s41598-017-16550-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704019PMC
November 2017

Host genetic variation in mucosal immunity pathways influences the upper airway microbiome.

Microbiome 2017 02 1;5(1):16. Epub 2017 Feb 1.

Department of Human Genetics, University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1186/s40168-016-0227-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286564PMC
February 2017

Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues.

PLoS Genet 2016 Nov 11;12(11):e1006423. Epub 2016 Nov 11.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106030PMC
November 2016

Association Tests for Rare Variants.

Authors:
Dan L Nicolae

Annu Rev Genomics Hum Genet 2016 08 21;17:117-30. Epub 2016 Apr 21.

Departments of Medicine and Statistics, University of Chicago, Chicago, Illinois 60637; email:

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http://dx.doi.org/10.1146/annurev-genom-083115-022609DOI Listing
August 2016

Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx.

Am J Hum Genet 2016 Apr 31;98(4):697-708. Epub 2016 Mar 31.

Department of Public Health Sciences, University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833292PMC
April 2016

A unified set-based test with adaptive filtering for gene-environment interaction analyses.

Biometrics 2016 06 23;72(2):629-38. Epub 2015 Oct 23.

Department of Public Health Sciences, The University of Chicago, Chicago, Illinois 60637, U.S.A.

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http://dx.doi.org/10.1111/biom.12428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842175PMC
June 2016

A gene-based association method for mapping traits using reference transcriptome data.

Nat Genet 2015 Sep 10;47(9):1091-8. Epub 2015 Aug 10.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ng.3367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552594PMC
September 2015

Genome-wide association study of recalcitrant atopic dermatitis in Korean children.

J Allergy Clin Immunol 2015 Sep 30;136(3):678-684.e4. Epub 2015 Apr 30.

Department of Pediatrics, Severance Hospital, Institute of Allergy, Brain Korea 21 PLUS project for Medical Science, Yonsei University College of Medicine, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.03.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562879PMC
September 2015

PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population.

PLoS Comput Biol 2015 Mar 3;11(3):e1004139. Epub 2015 Mar 3.

Department of Human Genetics, The University of Chicago, Chicago, Illinois, United States of America; Departments of Medicine, and Statistics, The University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348507PMC
March 2015

GWAS to Sequencing: Divergence in Study Design and Analysis.

Genes (Basel) 2014 May 28;5(2):460-76. Epub 2014 May 28.

Departments of Medicine, Statistics, and Human Genetics, University of Chicago, Chicago,IL 60637, USA.

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http://dx.doi.org/10.3390/genes5020460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094943PMC
May 2014

Marbled inflation from population structure in gene-based association studies with rare variants.

Genet Epidemiol 2013 Apr 6;37(3):286-92. Epub 2013 Mar 6.

Department of Health Studies, The University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/gepi.21714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716585PMC
April 2013

An exponential combination procedure for set-based association tests in sequencing studies.

Am J Hum Genet 2012 Dec 15;91(6):977-86. Epub 2012 Nov 15.

Department of Health Studies, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ajhg.2012.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516612PMC
December 2012

On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy.

Am J Hum Genet 2012 Apr 28;90(4):591-8. Epub 2012 Mar 28.

Department of Health Studies, University of Chicago, Chicago, IL, 60637, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000292971200093
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http://dx.doi.org/10.1016/j.ajhg.2012.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322234PMC
April 2012

Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals.

Genet Epidemiol 2012 May 28;36(4):312-9. Epub 2012 Mar 28.

Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1002/gepi.21623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794468PMC
May 2012

Replication analysis for severe diabetic retinopathy.

Invest Ophthalmol Vis Sci 2012 Apr 30;53(4):2377-81. Epub 2012 Apr 30.

Section of Ophthalmology and Visual Science, University of Chicago, Chicago, Illinois 60637, USA.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.11-8068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777289PMC
April 2012

Finding disease variants in Mendelian disorders by using sequence data: methods and applications.

Am J Hum Genet 2011 Dec 1;89(6):701-12. Epub 2011 Dec 1.

Department of Biostatistics, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.ajhg.2011.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234377PMC
December 2011

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

Nat Genet 2011 Jul 31;43(9):887-92. Epub 2011 Jul 31.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445408PMC
http://dx.doi.org/10.1038/ng.888DOI Listing
July 2011

Genome-wide meta-analysis for severe diabetic retinopathy.

Hum Mol Genet 2011 Jun 26;20(12):2472-81. Epub 2011 Mar 26.

Section of Ophthalmology and Visual Science, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddr121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098732PMC
June 2011

A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.

PLoS Genet 2011 Feb 3;7(2):e1001292. Epub 2011 Feb 3.

Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1001292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033384PMC
February 2011

An evolutionary framework for association testing in resequencing studies.

PLoS Genet 2010 Nov 11;6(11):e1001202. Epub 2010 Nov 11.

Department of Health Studies, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1001202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978703PMC
November 2010

You've gotta be lucky: Coverage and the elusive gene-gene interaction.

Ann Hum Genet 2011 Jan 26;75(1):105-11. Epub 2010 Oct 26.

Department of Statistics, The University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1111/j.1469-1809.2010.00615.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005128PMC
January 2011

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS.

PLoS Genet 2010 Apr 1;6(4):e1000888. Epub 2010 Apr 1.

Department of Medicine, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848547PMC
April 2010

Gene, region and pathway level analyses in whole-genome studies.

Genet Epidemiol 2010 Apr;34(3):222-231

Department of Statistics, The University of Chicago, 5734 S. University Ave., Chicago, IL 60637.

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http://doi.wiley.com/10.1002/gepi.20452
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http://dx.doi.org/10.1002/gepi.20452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061611PMC
April 2010

SCAN: SNP and copy number annotation.

Bioinformatics 2010 Jan 17;26(2):259-62. Epub 2009 Nov 17.

Department of Medicine, The University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1093/bioinformatics/btp644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852202PMC
January 2010

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors:
Marcin Imielinski Robert N Baldassano Anne Griffiths Richard K Russell Vito Annese Marla Dubinsky Subra Kugathasan Jonathan P Bradfield Thomas D Walters Patrick Sleiman Cecilia E Kim Aleixo Muise Kai Wang Joseph T Glessner Shehzad Saeed Haitao Zhang Edward C Frackelton Cuiping Hou James H Flory George Otieno Rosetta M Chiavacci Robert Grundmeier Massimo Castro Anna Latiano Bruno Dallapiccola Joanne Stempak Debra J Abrams Kent Taylor Dermot McGovern Gary Silber Iwona Wrobel Antonio Quiros Jeffrey C Barrett Sarah Hansoul Dan L Nicolae Judy H Cho Richard H Duerr John D Rioux Steven R Brant Mark S Silverberg Kent D Taylor M Michael Barmuda Alain Bitton Themistocles Dassopoulos Lisa Wu Datta Todd Green Anne M Griffiths Emily O Kistner Michael T Murtha Miguel D Regueiro Jerome I Rotter L Philip Schumm A Hillary Steinhart Stephen R Targan Ramnik J Xavier Cécile Libioulle Cynthia Sandor Mark Lathrop Jacques Belaiche Olivier Dewit Ivo Gut Simon Heath Debby Laukens Myriam Mni Paul Rutgeerts André Van Gossum Diana Zelenika Denis Franchimont J P Hugot Martine de Vos Severine Vermeire Edouard Louis Lon R Cardon Carl A Anderson Hazel Drummond Elaine Nimmo Tariq Ahmad Natalie J Prescott Clive M Onnie Sheila A Fisher Jonathan Marchini Jilur Ghori Suzannah Bumpstead Rhian Gwillam Mark Tremelling Panos Delukas John Mansfield Derek Jewell Jack Satsangi Christopher G Mathew Miles Parkes Michel Georges Mark J Daly Melvin B Heyman George D Ferry Barbara Kirschner Jessica Lee Jonah Essers Richard Grand Michael Stephens Arie Levine David Piccoli John Van Limbergen Salvatore Cucchiara Dimitri S Monos Stephen L Guthery Lee Denson David C Wilson Straun F A Grant Mark Daly Mark S Silverberg Jack Satsangi Hakon Hakonarson

Nat Genet 2009 Dec 15;41(12):1335-40. Epub 2009 Nov 15.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267927PMC
December 2009

Restricted parameter space models for testing gene-gene interaction.

Genet Epidemiol 2009 Jul;33(5):386-93

Department of Statistics, The University of Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/gepi.20392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077544PMC
July 2009

A common cortactin gene variation confers differential susceptibility to severe asthma.

Genet Epidemiol 2008 Dec;32(8):757-66

Department of Medicine, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/gepi.20343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774307PMC
December 2008

Association studies for untyped markers with TUNA.

Bioinformatics 2008 Feb 5;24(3):435-7. Epub 2007 Dec 5.

Department of Statistics, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/bioinformatics/btm603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051297PMC
February 2008

Smoking and inflammatory bowel disease: trends in familial and sporadic cohorts.

Inflamm Bowel Dis 2007 May;13(5):573-9

Midwest Gastroenterology Associates, Louisville, Kentucky, USA.

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http://dx.doi.org/10.1002/ibd.20043DOI Listing
May 2007

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

Science 2006 Dec 26;314(5804):1461-3. Epub 2006 Oct 26.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, University of Pittsburgh Medical Center Presbyterian, Mezzanine Level, C-Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1126/science.1135245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410764PMC
December 2006

Quantifying the amount of missing information in genetic association studies.

Authors:
Dan L Nicolae

Genet Epidemiol 2006 Dec;30(8):703-17

Departments of Medicine and Statistics, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1002/gepi.20181DOI Listing
December 2006

Testing untyped alleles (TUNA)-applications to genome-wide association studies.

Authors:
Dan L Nicolae

Genet Epidemiol 2006 Dec;30(8):718-27

Departments of Medicine and Statistics, The University of Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1002/gepi.20182DOI Listing
December 2006

GEL: a novel genotype calling algorithm using empirical likelihood.

Bioinformatics 2006 Aug 29;22(16):1942-7. Epub 2006 Jun 29.

Department of Statistics, The University of Chicago.

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http://dx.doi.org/10.1093/bioinformatics/btl341DOI Listing
August 2006

Coverage and characteristics of the Affymetrix GeneChip Human Mapping 100K SNP set.

PLoS Genet 2006 May 5;2(5):e67. Epub 2006 May 5.

Department of Statistics, The University of Chicago, Chicago, Illinois, USA.

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https://dx.plos.org/10.1371/journal.pgen.0020067
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http://dx.doi.org/10.1371/journal.pgen.0020067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456318PMC
May 2006

Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease.

Am J Physiol Gastrointest Liver Physiol 2006 Jun 26;290(6):G1157-63. Epub 2006 Jan 26.

Department of Pathology and Laboratory Medicine, Epithelial Pathobiology Unit, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1152/ajpgi.00544.2005DOI Listing
June 2006

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Sep;10(5):513-20

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1097/00054725-200409000-00004DOI Listing
September 2004

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations.

Hum Mol Genet 2004 Aug 15;13(16):1715-25. Epub 2004 Jun 15.

The Martin Boyer Laboratories, Gastroenterology Section, Department of Medicine, The University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddh182DOI Listing
August 2004

Measuring the relative information in allele-sharing linkage studies.

Biometrics 2004 Jun;60(2):368-75

Department of Statistics, University of Chicago, 5734 S. University Avenue, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1111/j.0006-341X.2004.00181.xDOI Listing
June 2004

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Jan;10(1):15-22

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/00054725-200401000-00002DOI Listing
January 2004

Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan.

Gastroenterology 2003 Jan;124(1):140-6

Martin Boyer Laboratories, Gastroenterology Section, Department of Medicine, University of Chicago Hospitals, Chicago, Illinois, USA.

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http://dx.doi.org/10.1053/gast.2003.50019DOI Listing
January 2003

MERLIN...and the geneticist's stone?

Nat Genet 2002 Jan;30(1):3-4

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http://dx.doi.org/10.1038/ng0102-3DOI Listing
January 2002