Publications by authors named "Dan G Duda"

100Publications

Combining microenvironment normalization strategies to improve cancer immunotherapy.

Proc Natl Acad Sci U S A 2020 02 3;117(7):3728-3737. Epub 2020 Feb 3.

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1919764117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035612PMC
February 2020

Overcoming sorafenib treatment-resistance in hepatocellular carcinoma: A future perspective at a time of rapidly changing treatment paradigms.

EBioMedicine 2020 Feb 31;52:102644. Epub 2020 Jan 31.

Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St, Cox-734, Boston, MA 02114, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2020.102644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997488PMC
February 2020

A phase II study of cabozantinib alone or in combination with trastuzumab in breast cancer patients with brain metastases.

Breast Cancer Res Treat 2020 Jan 20;179(1):113-123. Epub 2019 Sep 20.

Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-019-05445-zDOI Listing
January 2020

Role of Apelin in Glioblastoma Vascularization and Invasion after Anti-VEGF Therapy: What Is the Impact on the Immune System?

Cancer Res 2019 05;79(9):2104-2106

Edwin L. Steele Laboratories for Tumor Biology and Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-19-0749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601607PMC
May 2019

Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer.

NPJ Breast Cancer 2019 15;5. Epub 2019 Jan 15.

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41523-018-0100-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333771PMC
January 2019

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges.

Nat Rev Clin Oncol 2018 05 6;15(5):325-340. Epub 2018 Mar 6.

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2018.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921900PMC
May 2018

New Perspective on the Treatment of Intractable Gastrointestinal Cancers: Role of Combination Therapies.

Authors:
Dan G Duda

Keio J Med 2017 ;66(4):72

Massachusetts General Hospital, Boston, USA Massachusetts General Hospital Research Institute, Boston, USA Harvard Medical School, Boston, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2302/kjm.66-006-ABSTDOI Listing
July 2018

Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect.

Oncolytic Virother 2017 8;6:39-49. Epub 2017 Nov 8.

Division of Hematology Oncology, Department of Medicine, Mayo Clinic, Scottsdale.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/OV.S145262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687448PMC
November 2017

Can smart nanomedicine deliver effective targeted cytotoxic treatments to hepatocellular carcinomas while reducing the liver damage?

Hepatology 2018 03 30;67(3):826-828. Epub 2018 Jan 30.

Edwin L. Steele Laboratories, Department of Radiation Oncology.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.29617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826834PMC
March 2018

A cerebellar window for intravital imaging of normal and disease states in mice.

Nat Protoc 2017 Nov 5;12(11):2251-2262. Epub 2017 Oct 5.

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2017.101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918134PMC
November 2017

Nonalcoholic steatohepatitis-related hepatocellular carcinoma: is there a role for the androgen receptor pathway?

Onco Targets Ther 2017 3;10:1403-1412. Epub 2017 Mar 3.

Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/OTT.S111681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344425PMC
March 2017

Anti-angiogenesis for cancer revisited: Is there a role for combinations with immunotherapy?

Angiogenesis 2017 May 30;20(2):185-204. Epub 2017 Mar 30.

E. L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom St, Cox-734, Boston, MA, 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10456-017-9552-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439974PMC
May 2017

Phase II study of tivozanib, an oral VEGFR inhibitor, in patients with recurrent glioblastoma.

J Neurooncol 2017 02 16;131(3):603-610. Epub 2016 Nov 16.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital Cancer Center, Yawkey 9E, 55 Fruit Street, Boston, MA, 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11060-016-2332-5DOI Listing
February 2017

Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity.

Cold Spring Harb Perspect Med 2016 Dec 1;6(12). Epub 2016 Dec 1.

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a027094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131751PMC
December 2016

Role of stromal cell-derived factor 1α pathway in bone metastatic prostate cancer.

J Biomed Res 2016 May 2;30(3):181-5. Epub 2015 Nov 2.

Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital Research Institute, Harvard Medical School, 100 Blossom Street, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7555/JBR.30.20150114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885164PMC
May 2016

Immune modulation by hypofractionated stereotactic radiation therapy: Therapeutic implications.

Radiother Oncol 2016 08 2;120(2):185-94. Epub 2016 Aug 2.

Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2016.07.013DOI Listing
August 2016

Efficacy and Biomarker Study of Bevacizumab for Hearing Loss Resulting From Neurofibromatosis Type 2-Associated Vestibular Schwannomas.

J Clin Oncol 2016 05 14;34(14):1669-75. Epub 2016 Mar 14.

Jaishri O. Blakeley, Xiaobu Ye, Amanda L. Bergner, Laura M. Fayad, Shivani Ahlawat, and Michael A. Jacobs, Johns Hopkins University, Baltimore; Christopher Zalewski, National Institute on Deafness and Other Communication Disorders; Eva Dombi and Brigitte C. Widemann, National Cancer Institute, Bethesda, MD; Dan G. Duda, Alona Muzikansky, Vanessa L. Merker, Elizabeth R. Gerstner, Rakesh K. Jain, and Scott R. Plotkin, Massachusetts General Hospital; and Chris F. Halpin, Massachusetts Eye and Ear Infirmary, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2015.64.3817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872317PMC
May 2016

Exploration of Imaging Biomarkers for Predicting Survival of Patients With Advanced Non-Small Cell Lung Cancer Treated With Antiangiogenic Chemotherapy.

AJR Am J Roentgenol 2016 May 2;206(5):987-93. Epub 2016 Mar 2.

1 Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2214/AJR.15.15528DOI Listing
May 2016

Rationally combining anti-VEGF therapy with checkpoint inhibitors in hepatocellular carcinoma.

Immunotherapy 2016 11;8(3):299-313. Epub 2016 Feb 11.

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/imt.15.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619018PMC
December 2016

Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment.

J Natl Cancer Inst 2016 Feb 7;108(2). Epub 2015 Nov 7.

: Edwin L. Steele Laboratories, Department of Radiation Oncology (VA, GBF, DPK, MB, RCS, GS, JK, TV, JDM, KN, DB, XQ, DGD, PH, DF, RKJ), Department of Pathology (MKS, EB), and Department of Medicine, Cancer Center (JAE), Massachusetts General Hospital and Harvard Medical School, Boston MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862418PMC
February 2016

Vascular diseases await translation of blood vessels engineered from stem cells.

Sci Transl Med 2015 Oct;7(309):309rv6

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.aaa1805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799660PMC
October 2015

Targeting immunosuppression after standard sorafenib treatment to facilitate immune checkpoint blockade in hepatocellular carcinoma - an auto-commentary on clinical potential and future development.

Oncoimmunology 2015 Oct 27;4(10):e1029703. Epub 2015 May 27.

Steele Laboratories for Tumor Biology; Department of Radiation Oncology; Massachusetts General Hospital and Harvard Medical School ; Boston, MA USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/2162402X.2015.1029703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589048PMC
October 2015

Familial Gastric Cancers.

Oncologist 2015 Dec 30;20(12):1365-77. Epub 2015 Sep 30.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2015-0205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679084PMC
December 2015

An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis.

Nat Protoc 2015 Aug 23;10(8):1264-74. Epub 2015 Jul 23.

Department of Radiation Oncology, Steele Laboratories for Tumor Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2015.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800979PMC
August 2015

Chemotherapy and antiangiogenics in biliary tract cancer.

Lancet Oncol 2015 Aug 12;16(8):882-3. Epub 2015 Jul 12.

Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(15)00093-5DOI Listing
August 2015

Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors.

J Am Chem Soc 2015 Aug 29;137(31):9832-42. Epub 2015 Jul 29.

†Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.5b04765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750386PMC
August 2015

Reply to Ciccolini et al.: Using mathematical modeling to predict response to antiangiogenic therapy in cancer patients.

Proc Natl Acad Sci U S A 2015 Jul 16;112(27):E3454. Epub 2015 Jun 16.

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1507225112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500270PMC
July 2015

Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases.

J Natl Cancer Inst 2015 Sep 10;107(9). Epub 2015 Jun 10.

Edwin L. Steele Laboratories, Department of Radiation Oncology, MGH Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA (HSJ, DJ, SL, DAW, CC, DGD, RKJ, TPP); Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea (HSJ); Department of Radiation Oncology, Duke University Medical Center, Durham, NC (CGW).Current affiliation: Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada (SL).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651102PMC
September 2015

Lessons From 30 Years of Teaching About the Microenvironment of Tumors.

Cancer J 2015 May-Jun;21(3):137

From Massachusetts General Hospital Research Institute and Harvard Medical School, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PPO.0000000000000119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792516PMC
February 2016

A phase I study of cediranib in combination with cilengitide in patients with recurrent glioblastoma.

Neuro Oncol 2015 Oct 24;17(10):1386-92. Epub 2015 May 24.

Massachusetts General Hospital Cancer Center, Boston, Massachusetts (E.R.G., D.G.D., R.K.J., T.T.B.); Johns Hopkins Medical Center, Baltimore, Maryland (X.Y., S.G.); Martinos Center for Biomedical Imaging, Charlestown, Massachusetts (E.R.G., M.A.L.); Henry Ford Hospital, Detroit, Michigan (T.M.); Memorial Sloan Kettering Cancer Center, New York, New York (T.J.K.); Emory University, Atlanta, Georgia (J.J.O.); University of Alabama, Birmingham, Alabama (B.L.N.); Case Comprehensive Cancer Center, Cleveland, Ohio (M.S.A.); Dana-Farber Cancer Institute, Boston, Massachusetts (P.Y.W.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/nov085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578584PMC
October 2015

Texture Analysis of Non-Contrast-Enhanced Computed Tomography for Assessing Angiogenesis and Survival of Soft Tissue Sarcoma.

J Comput Assist Tomogr 2015 Jul-Aug;39(4):607-12

From the *Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Boston, MA; †Department of Radiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China; ‡Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY; §Steele Laboratory, Massachusetts General Hospital, Boston, MA; and ∥Institute of Nuclear Medicine, University College London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/RCT.0000000000000239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504795PMC
September 2015

Quantum dot/antibody conjugates for in vivo cytometric imaging in mice.

Proc Natl Acad Sci U S A 2015 Feb 20;112(5):1350-5. Epub 2015 Jan 20.

Edwin L. Steele Laboratory, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1421632111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321304PMC
February 2015

CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice.

Hepatology 2015 May 20;61(5):1591-602. Epub 2015 Mar 20.

E.L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA; Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.27665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406806PMC
May 2015

Radiation-induced changes in hepatocyte-specific Gd-EOB-DTPA enhanced MRI: potential mechanism.

Med Hypotheses 2014 Oct 11;83(4):477-81. Epub 2014 Aug 11.

Massachusetts General Hospital and Harvard Medical School, Department of Radiation Oncology, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mehy.2014.08.004DOI Listing
October 2014

Seeds and soil: unraveling the role of local tumor stroma in distant metastasis.

J Natl Cancer Inst 2014 Aug 31;106(8). Epub 2014 Jul 31.

Steele Laboratory for Tumor Biology, Department of Radiation Oncology (DGD, RKJ), and Department of Medicine (SJI), Massachusetts General Hospital and Harvard Medical School, Boston, MA; PAREXEL International, Waltham, MA (MA); Department of Medicine, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA (IEK).

View Article

Download full-text PDF

Source
http://jnci.oxfordjournals.org/content/106/8/dju187.full.pdf
Web Search
http://jnci.oxfordjournals.org/cgi/doi/10.1093/jnci/dju187
Publisher Site
http://dx.doi.org/10.1093/jnci/dju187DOI Listing
August 2014

Immune checkpoint blockade in hepatocellular carcinoma: current progress and future directions.

Hepatology 2014 Nov 26;60(5):1776-82. Epub 2014 Sep 26.

Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hep.27246
Publisher Site
http://dx.doi.org/10.1002/hep.27246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211962PMC
November 2014

Characterization of functional transient receptor potential melastatin 8 channels in human pancreatic ductal adenocarcinoma cells.

Pancreas 2014 Jul;43(5):795-800

From the *Center of Digestive Disease and Liver Transplantation, Fundeni Clinical Institute; †Department of Molecular and Cell Biology, Romanian Academy Institute of Biochemistry; ‡Department of Anatomy, Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania; §Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA; and ∥Division of Molecular Pathology, Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.

View Article

Download full-text PDF

Source
https://insights.ovid.com/crossref?an=00006676-201407000-000
Publisher Site
http://dx.doi.org/10.1097/MPA.0000000000000106DOI Listing
July 2014

Benefits of vascular normalization are dose and time dependent--letter.

Cancer Res 2013 Dec 21;73(23):7144-6. Epub 2013 Nov 21.

Authors' Affiliation: Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-13-1989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876035PMC
December 2013

A phase II and biomarker study of ramucirumab, a human monoclonal antibody targeting the VEGF receptor-2, as first-line monotherapy in patients with advanced hepatocellular cancer.

Clin Cancer Res 2013 Dec 2;19(23):6614-23. Epub 2013 Oct 2.

Authors' Affiliations: Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts; David Geffen School of Medicine, University of California, Los Angeles, California; Northwestern University Feinberg School of Medicine, Chicago Illinois; East Jefferson General Hospital, Metairie, Louisiana; Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; ImClone Systems, a wholly-owned subsidiary of Eli Lilly and company, Bridgewater, New Jersey; Eli Lilly and Company, Indianapolis, Indiana; and Lahey Hospital and Medical Center, Tufts University School of Medicine, Burlington, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-1442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795808PMC
December 2013

Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells.

Proc Natl Acad Sci U S A 2013 Jul 16;110(31):12774-9. Epub 2013 Jul 16.

Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1310675110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732948PMC
July 2013

Magnetic resonance imaging biomarkers in hepatocellular carcinoma: association with response and circulating biomarkers after sunitinib therapy.

J Hematol Oncol 2013 Jul 10;6:51. Epub 2013 Jul 10.

Division of Abdominal Imaging and Intervention, Harvard Medical School and Massachusetts General Hospital, 55 Fruit Street, White 270, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-8722-6-51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722053PMC
July 2013

Vascular normalization as an emerging strategy to enhance cancer immunotherapy.

Cancer Res 2013 May 25;73(10):2943-8. Epub 2013 Feb 25.

Edwin L. Steele Laboratory of Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-12-4354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655127PMC
May 2013

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.

Proc Natl Acad Sci U S A 2012 Oct 8;109(43):17561-6. Epub 2012 Oct 8.

Edwin L Steele Laboratory of Tumor Biology, Department of Radiation Oncology and Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1215397109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491458PMC
October 2012

Going beyond systemic fluoropyrimidines with radiation therapy for rectal cancer: what should be the priority?

Oncology (Williston Park) 2012 Aug;26(8):741-3

Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682651PMC
August 2012

Neovascularization after irradiation: what is the source of newly formed vessels in recurring tumors?

J Natl Cancer Inst 2012 Jun 9;104(12):899-905. Epub 2012 May 9.

Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, 100 Blossom Street, Cox-734, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djs239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379722PMC
June 2012

A transient parabiosis skin transplantation model in mice.

Nat Protoc 2012 Mar 22;7(4):763-70. Epub 2012 Mar 22.

Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital (MGH) and Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2012.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375333PMC
March 2012