Publications by authors named "Dan A Landau"

26Publications

Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics.

Nat Rev Genet 2021 Jan 17;22(1):3-18. Epub 2020 Aug 17.

New York Genome Center, New York, NY, USA.

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January 2021

Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells.

Cell Rep 2020 06;31(9):107688

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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June 2020

Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization.

Cell Syst 2020 01 23;10(1):52-65.e7. Epub 2019 Oct 23.

Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; New York Genome Center, New York, NY 10013, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address:

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January 2020

mA RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.

Cell Rep 2019 08;28(7):1703-1716.e6

Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

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August 2019

TARGET-seq Takes Aim at Cancer Evolution through Multi-omics Single-Cell Genotyping and Transcriptomics.

Mol Cell 2019 03;73(6):1092-1094

Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; New York Genome Center, New York, NY, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA. Electronic address:

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March 2019

Cancer Evolution: No Room for Negative Selection.

Cell 2017 11;171(5):987-989

Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Division of Hematology and Medical Oncology, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA; New York Genome Center, New York, NY 10013, USA. Electronic address:

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November 2017

Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.

Cancer Cell 2016 Nov 3;30(5):750-763. Epub 2016 Nov 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Dana 540, 44 Binney Street, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02141, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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November 2016

Genomic complexity of multiple myeloma and its clinical implications.

Nat Rev Clin Oncol 2017 02 17;14(2):100-113. Epub 2016 Aug 17.

Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, HIM 237, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

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February 2017

Genetic and epigenetic determinants of B-cell lymphoma evolution.

Curr Opin Hematol 2016 07;23(4):392-401

aMeyer Cancer Center, Weill Cornell Medicine bNew York Genome Center, New York, New York, USA cInstituto de Biología y Medicina Experimental (IBYME), CONICET, Buenos Aires, Argentina.

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July 2016