Damu Tang

Damu Tang

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The Oncogenic Potential of the Centromeric Border Protein FAM84B of the 8q24.21 Gene Desert.

Genes (Basel) 2020 Mar 15;11(3). Epub 2020 Mar 15.

Urological Cancer Center for Research and Innovation (UCCRI), St Joseph's Hospital, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.3390/genes11030312DOI Listing
March 2020

Contributions of DNA Damage to Alzheimer's Disease.

Int J Mol Sci 2020 Feb 28;21(5). Epub 2020 Feb 28.

Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.

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http://dx.doi.org/10.3390/ijms21051666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084447PMC
February 2020

Oxidative stress contributes to vascular calcification in patients with chronic kidney disease.

J Mol Cell Cardiol 2020 Jan 19;138:256-268. Epub 2019 Dec 19.

Division of Nephrology, Xiangya Hospital of the Central South University, Changsha, Hunan 410008, China; 1717 class, Chang Jun High School of Changsha, Changsha, Hunan 410002, China.

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http://dx.doi.org/10.1016/j.yjmcc.2019.12.006DOI Listing
January 2020

Assessment of biochemical recurrence of prostate cancer (Review).

Int J Oncol 2019 Dec 4;55(6):1194-1212. Epub 2019 Oct 4.

Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.

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http://dx.doi.org/10.3892/ijo.2019.4893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831208PMC
December 2019

Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation.

Free Radic Biol Med 2019 06 13;137:24-36. Epub 2019 Apr 13.

Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.04.012DOI Listing
June 2019

FAM84B promotes prostate tumorigenesis through a network alteration.

Ther Adv Med Oncol 2019 13;11:1758835919846372. Epub 2019 May 13.

Department of Medicine, McMaster University, T3310, St. Joseph's Hospital, 50 Charlton Avenue East, Hamilton, ON, L8N 4A6, Canada.

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http://dx.doi.org/10.1177/1758835919846372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535720PMC
May 2019

Downregulation of CYB5D2 is associated with breast cancer progression.

Sci Rep 2019 04 29;9(1):6624. Epub 2019 Apr 29.

Department of Medicine, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1038/s41598-019-43006-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488675PMC
April 2019

The Contributions of Prostate Cancer Stem Cells in Prostate Cancer Initiation and Metastasis.

Cancers (Basel) 2019 Mar 27;11(4). Epub 2019 Mar 27.

Department of Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.

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http://dx.doi.org/10.3390/cancers11040434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521153PMC
March 2019

The TGFβ-ERK pathway contributes to Notch3 upregulation in the renal tubular epithelial cells of patients with obstructive nephropathy.

Cell Signal 2018 11 4;51:139-151. Epub 2018 Aug 4.

1717 Class, ChangJun High School of Changsha, Changsha, Hunan 410002, China.

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http://dx.doi.org/10.1016/j.cellsig.2018.08.002DOI Listing
November 2018

Construction of a set of novel and robust gene expression signatures predicting prostate cancer recurrence.

Mol Oncol 2018 09 11;12(9):1559-1578. Epub 2018 Aug 11.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1002/1878-0261.12359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120243PMC
September 2018

Biphasic Alteration of Butyrylcholinesterase (BChE) During Prostate Cancer Development.

Transl Oncol 2018 Aug 30;11(4):1012-1022. Epub 2018 Jun 30.

Division of Nephrology, Department of Medicine, McMaster University, St. Joseph's Hospital, Hamilton, Ontario, Canada; the Research Institute of St Joe's Hamilton, St. Joseph's Hospital, Hamilton, Ontario, Canada; the Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2018.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031255PMC
August 2018

Polycomb complex protein BMI1 confers resistance to tamoxifen in estrogen receptor positive breast cancer.

Cancer Lett 2018 07 4;426:4-13. Epub 2018 Apr 4.

Division of Nephrology, Department of Medicine, McMaster University, Canada; Research Institute of St. Joe's Hamilton, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.03.048DOI Listing
July 2018

Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response.

Oncotarget 2018 May 16;9(35):24122-24139. Epub 2018 Feb 16.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.18632/oncotarget.24517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963631PMC
May 2018

A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer.

Biochim Biophys Acta Mol Basis Dis 2018 Mar 14;1864(3):735-745. Epub 2017 Dec 14.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Father Sean O'Sullivan Research Institute, Hamilton, Ontario, Canada; the Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.12.018DOI Listing
March 2018

Signatures derived from increase in SHARPIN gene copy number are associated with poor prognosis in patients with breast cancer.

BBA Clin 2017 Dec 24;8:56-65. Epub 2017 Aug 24.

Division of Nephrology, Department of Medicine, McMaster University, St. Joseph's Hospital, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.bbacli.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582379PMC
December 2017

Overexpression of MUC1 and Genomic Alterations in Its Network Associate with Prostate Cancer Progression.

Neoplasia 2017 Nov 18;19(11):857-867. Epub 2017 Sep 18.

Division of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; Hamilton Center for Kidney Research, St. Joseph's Hospital. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2017.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605493PMC
November 2017

Next Generation Quality: Assessing the Physician in Clinical History Completeness and Diagnostic Interpretations Using Funnel Plots and Normalized Deviations Plots in 3,854 Prostate Biopsies.

J Pathol Inform 2017 23;8:43. Epub 2017 Nov 23.

Division of Urology, Juravinski Cancer Centre, St. Joseph's Healthcare Hamilton, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.4103/jpi.jpi_50_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719585PMC
November 2017

BMI1 reduces ATR activation and signalling caused by hydroxyurea.

Oncotarget 2017 Oct 20;8(52):89707-89721. Epub 2017 Sep 20.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.18632/oncotarget.21111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685703PMC
October 2017

Microvesicles Contribute to the Bystander Effect of DNA Damage.

Int J Mol Sci 2017 Apr 7;18(4). Epub 2017 Apr 7.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.3390/ijms18040788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412372PMC
April 2017

Amplification of MUC1 in prostate cancer metastasis and CRPC development.

Oncotarget 2016 Dec;7(50):83115-83133

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.18632/oncotarget.13073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347757PMC
December 2016

Hematoporphyrin monomethyl ether combined with He-Ne laser irradiation-induced apoptosis in canine breast cancer cells through the mitochondrial pathway.

J Vet Sci 2016 Jun;17(2):235-42

Department of Clinic Veterinary Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.

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http://dx.doi.org/10.4142/jvs.2016.17.2.235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921672PMC
June 2016

Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion.

Curr Med Chem 2015 ;22(19):2360-74

T3310, St. Joseph's Hospital, 50 Charlton Ave East, Hamilton, Ontario, Canada, L8N 4A6.

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http://dx.doi.org/10.2174/0929867322666150416095744DOI Listing
April 2016

Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk.

PLoS One 2015 19;10(5):e0127546. Epub 2015 May 19.

Division of Nephrology, Department of Medicine, McMaster University, Ontario, Canada; Father Sean O'Sullivan Research Institute, Ontario, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127546PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4438068PMC
April 2016

CYB5D2 displays tumor suppression activities towards cervical cancer.

Biochim Biophys Acta 2016 04 12;1862(4):556-565. Epub 2015 Dec 12.

Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O'Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.12.013DOI Listing
April 2016

Dataset on the effects of CYB5D2 on the distribution of HeLa cervical cancer cell cycle.

Data Brief 2016 Mar 28;6:811-6. Epub 2016 Jan 28.

Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O'Sullivan Research Institute, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Canada.

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http://dx.doi.org/10.1016/j.dib.2016.01.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749936PMC
March 2016

Fluorofenidone offers improved renoprotection at early interventions during the course of diabetic nephropathy in db/db mice via multiple pathways.

PLoS One 2014 27;9(10):e111242. Epub 2014 Oct 27.

Division of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, China; State Key Laboratory of Medical Genetics of China, Central South University, Changsha, Hunan, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111242PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210223PMC
December 2015

A Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage Response.

Biomolecules 2015 Dec 1;5(4):3396-415. Epub 2015 Dec 1.

Department of Medicine, Division of Nephrology, McMaster University, Hamilton, ON L8S 4L8, Canada.

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http://dx.doi.org/10.3390/biom5043396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693283PMC
December 2015

Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis.

Nephrology (Carlton) 2015 Nov;20(11):832-42

Division of Nephrology, Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.1111/nep.12515DOI Listing
November 2015

Prostate Cancer Stem-like Cells Contribute to the Development of Castration-Resistant Prostate Cancer.

Cancers (Basel) 2015 Nov 18;7(4):2290-308. Epub 2015 Nov 18.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.3390/cancers7040890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695890PMC
November 2015

BMI1, ATM and DDR.

Oncoscience 2015 21;2(8):665-6. Epub 2015 Aug 21.

Division of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute, The Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580051PMC
http://dx.doi.org/10.18632/oncoscience.211DOI Listing
October 2015

PKM2 contributes to cancer metabolism.

Cancer Lett 2015 Jan 4;356(2 Pt A):184-91. Epub 2014 Feb 4.

Division of Nephrology, Department of Medicine, Hamilton, Ontario, Canada; Division of Urology, Department of Surgery, McMaster University, Hamilton, Ontario, Canada; Father Sean O'Sullivan Research Institute, Hamilton, Ontario, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.01.031DOI Listing
January 2015

SIPL1-facilitated PTEN ubiquitination contributes to its association with PTEN.

Cell Signal 2014 Dec 22;26(12):2749-56. Epub 2014 Aug 22.

Division of Nephrology, Department of Medicine, McMaster University, Canada; Father Sean O'Sullivan Research Institute, St. Joseph's Hospital, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.08.013DOI Listing
December 2014

Prostate cancer stem-like cells proliferate slowly and resist etoposide-induced cytotoxicity via enhancing DNA damage response.

Authors:
Judy Yan Damu Tang

Exp Cell Res 2014 Oct 20;328(1):132-42. Epub 2014 Aug 20.

Division of Nephrology, Department of Medicine, McMaster University, Juravinski Innovation Tower, Room T3310, St. Joseph׳s Hospital, 50 Charlton Ave East, Hamilton, Ontario, Canada L8S 4L8; Father Sean O׳Sullivan Research Institute, Hamilton, Ontario, Canada L8N 4A6; The Hamilton Centre for Kidney Research (HCKR), St. Joseph׳s Hamilton Healthcare, Hamilton, Ontario, Canada L8N 4A6. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.08.016DOI Listing
October 2014

SIPL1 enhances the proliferation, attachment, and migration of CHO cells by inhibiting PTEN function.

Int J Mol Med 2014 Sep 8;34(3):835-41. Epub 2014 Jul 8.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON L8N 4A6, Canada.

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http://dx.doi.org/10.3892/ijmm.2014.1840DOI Listing
September 2014

Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma.

Oncotarget 2014 Sep;5(17):7406-19

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada, Hamilton, Ontario, Canada. Father Sean O'Sullivan Research Institute, Hamilton, Ontario, Canada. The Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202132PMC
http://dx.doi.org/10.18632/oncotarget.1558DOI Listing
September 2014

Changes in PKM2 associate with prostate cancer progression.

Cancer Invest 2014 Aug 2;32(7):330-8. Epub 2014 Jun 2.

Division of Nephrology, Department of Medicine, McMaster University,1.

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http://dx.doi.org/10.3109/07357907.2014.919306DOI Listing
August 2014

Contactin-1 reduces E-cadherin expression via activating AKT in lung cancer.

PLoS One 2013 28;8(5):e65463. Epub 2013 May 28.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065463PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665745PMC
January 2014

ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response.

Histol Histopathol 2013 12 9;28(12):1547-54. Epub 2013 Jul 9.

Division of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; and the Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.14670/HH-28.1547DOI Listing
December 2013

SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells.

Cell Signal 2013 Dec 13;25(12):2734-42. Epub 2013 Sep 13.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Father Sean O'Sullivan Research Institute, Hamilton, Ontario, Canada; The Hamilton Centre for Kidney Research (HCKR), St. Joseph's Hospital, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cellsig.2013.08.041DOI Listing
December 2013

Effect of hematoporphyrin monomethyl ether-mediated PDT on the mitochondria of canine breast cancer cells.

Photodiagnosis Photodyn Ther 2013 Dec 25;10(4):414-21. Epub 2013 Apr 25.

Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin, China; Department of Veterinary Clinic, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.

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http://dx.doi.org/10.1016/j.pdpdt.2013.03.005DOI Listing
December 2013

Propagation of human prostate cancer stem-like cells occurs through EGFR-mediated ERK activation.

PLoS One 2013 19;8(4):e61716. Epub 2013 Apr 19.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061716PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631151PMC
November 2013

Clear cell renal cell carcinoma induces fibroblast-mediated production of stromal periostin.

Eur J Cancer 2013 Nov 26;49(16):3537-46. Epub 2013 Jul 26.

Division of Nephrology, Department of Medicine, St. Joseph's Hospital, Hamilton, Ontario, Canada; Department of Surgery, McMaster University, St. Joseph's Hospital, Hamilton, Ontario, Canada; Father Sean O'Sullivan Research Institute, St. Joseph's Hospital, Hamilton, Ontario, Canada; The Hamilton Center for Kidney Research, St. Joseph's Hospital, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ejca.2013.06.032DOI Listing
November 2013

PKM2, a Central Point of Regulation in Cancer Metabolism.

Int J Cell Biol 2013 14;2013:242513. Epub 2013 Feb 14.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada L8S 4L8 ; Division of Urology, Department of Surgery, McMaster University, Hamilton, ON, Canada L8S 4L8 ; Father Sean O'Sullivan Research Centre, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada L8N 4A6 ; The Hamilton Center for Kidney Research, St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada L8N 4A6.

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http://dx.doi.org/10.1155/2013/242513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586519PMC
March 2013

Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation.

Biochim Biophys Acta 2013 Jan 23;1833(1):90-100. Epub 2012 Oct 23.

The Genetics Laboratory, Maternity and Child Healthcare Hospital, Shenzhen, Guangdong, People's Republic of China.

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http://dx.doi.org/10.1016/j.bbamcr.2012.10.016DOI Listing
January 2013

IQGAP2, A candidate tumour suppressor of prostate tumorigenesis.

Biochim Biophys Acta 2012 Jun 2;1822(6):875-84. Epub 2012 Mar 2.

Division of Nephrology, Department of Medicine, Canada.

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http://dx.doi.org/10.1016/j.bbadis.2012.02.019DOI Listing
June 2012

α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells.

Nat Commun 2011 ;2:307

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada L8N 4A6.

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http://dx.doi.org/10.1038/ncomms1309DOI Listing
November 2011

Apoptosis induced by hematoporphyrin monomethyl ether combined with He-Ne laser irradiation in vitro on canine breast cancer cells.

Vet J 2011 Jun 16;188(3):325-30. Epub 2010 Jun 16.

Department of Veterinary Clinic, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.

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http://dx.doi.org/10.1016/j.tvjl.2010.05.013DOI Listing
June 2011

CYB5D2 enhances HeLa cells survival of etoposide-induced cytotoxicity.

Biochem Cell Biol 2011 Jun 6;89(3):341-50. Epub 2011 Jun 6.

Division of Nephrology, Department of Medicine, McMaster University, St. Joseph's Hospital, Hamilton, ON, Canada.

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http://dx.doi.org/10.1139/o11-004DOI Listing
June 2011

Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells.

Biochim Biophys Acta 2011 May 26;1813(5):683-94. Epub 2011 Jan 26.

Division of Nephrology, Department of Medicine, Canada.

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http://dx.doi.org/10.1016/j.bbamcr.2011.01.018DOI Listing
May 2011

ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation.

Cell Signal 2011 Jan 15;23(1):259-68. Epub 2010 Sep 15.

Division of Nephrology, Department of Medicine, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cellsig.2010.09.010DOI Listing
January 2011

Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation.

Cell Signal 2010 Nov 15;22(11):1783-9. Epub 2010 Jul 15.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cellsig.2010.07.007DOI Listing
November 2010

Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells.

J Clin Invest 2010 Jun 10;120(6):2094-108. Epub 2010 May 10.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1172/JCI40778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877943PMC
June 2010

PTEN inhibits BMI1 function independently of its phosphatase activity.

Mol Cancer 2009 Nov 10;8:98. Epub 2009 Nov 10.

Division of Nephrology, Department of Medicine, McMaster University, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1186/1476-4598-8-98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777864PMC
November 2009

Specific reduction of fas-associated protein with death domain (FADD) in clear cell renal cell carcinoma.

Cancer Invest 2009 Oct;27(8):836-43

Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, P.R. China.

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http://dx.doi.org/10.1080/07357900902849681DOI Listing
October 2009

Bmi1 promotes prostate tumorigenesis via inhibiting p16(INK4A) and p14(ARF) expression.

Biochim Biophys Acta 2008 Nov 6;1782(11):642-8. Epub 2008 Sep 6.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/j.bbadis.2008.08.009DOI Listing
November 2008

Interaction of p14ARF with Brca1 in cancer cell lines and primary breast cancer.

Cell Biol Int 2008 Oct 25;32(10):1302-9. Epub 2008 Jul 25.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/j.cellbi.2008.07.018DOI Listing
October 2008

Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3'K and ERK1/2 MAPK signal transduction pathways.

Cell Signal 2008 Jun 11;20(6):1142-50. Epub 2008 Feb 11.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada L8N 3Z5.

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http://dx.doi.org/10.1016/j.cellsig.2008.02.001DOI Listing
June 2008

Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2.

Int J Biochem Cell Biol 2007 16;39(10):1843-51. Epub 2007 May 16.

Henderson Research Centre, McMaster University, 711 Concession Street, Hamilton, Ont., Canada L8V 1C3.

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http://dx.doi.org/10.1016/j.biocel.2007.05.002DOI Listing
January 2008

Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma.

Biochim Biophys Acta 2007 Oct 12;1772(10):1134-42. Epub 2007 Jul 12.

Division of Nephrology, Department of Medicine, McMaster University, and Father Sean O'Sullivan Research Centre, St. Joseph's Hospital, 50 Charlton Ave East, Hamilton, ON, Canada L8N 4A6.

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http://dx.doi.org/10.1016/j.bbadis.2007.07.001DOI Listing
October 2007

ATM activation is accompanied with earlier stages of prostate tumorigenesis.

Biochim Biophys Acta 2006 Oct 24;1763(10):1090-7. Epub 2006 Aug 24.

Department of Medicine, McMaster University, Hamilton, ON, Canada L8N 4A6.

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http://dx.doi.org/10.1016/j.bbamcr.2006.08.026DOI Listing
October 2006

[P21 expression in renal interstitial fibrosis and regulative effect of enalapril].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006 Oct;31(5):663-6, 670

Department of Nephrology, Xiangya Hospital, Central South University, Changsha 410008, China.

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October 2006

[Expression of p27 in rat kidney with unilateral ureteral obstruction and the therapeutic effect of enalapril].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006 Oct;31(5):671-5

Department of Nephrology, Xiangya Hospital, Central South University, Changsha 410008, China.

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October 2006

p14ARF inhibits the growth of p53 deficient cells in a cell-specific manner.

Biochim Biophys Acta 2006 Aug 6;1763(8):787-96. Epub 2006 May 6.

Department of Medicine, Division of Nephrology, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/j.bbamcr.2006.04.011DOI Listing
August 2006

Akt mediates mechanical strain-induced collagen production by mesangial cells.

J Am Soc Nephrol 2005 Jun 6;16(6):1661-72. Epub 2005 Apr 6.

Department of Medicine, Division of Nephrology, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1681/ASN.2004100897DOI Listing
June 2005

Identification of a novel Wee1 isoform.

Biochim Biophys Acta 2005 May 9;1729(1):1-9. Epub 2005 Mar 9.

Department of Biochemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, P.R. China.

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http://dx.doi.org/10.1016/j.bbaexp.2005.02.006DOI Listing
May 2005

Stretch-induced Raf-1 activation in mesangial cells requires actin cytoskeletal integrity.

Cell Signal 2005 Mar;17(3):311-20

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cellsig.2004.07.010DOI Listing
March 2005

ATM activity contributes to the tumor-suppressing functions of p14ARF.

Oncogene 2004 Sep;23(44):7355-65

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1038/sj.onc.1207957DOI Listing
September 2004

Activation of mesangial cell MAPK in response to homocysteine.

Kidney Int 2004 Aug;66(2):733-45

Department of Medicine, McMaster University, Hamilton, Ontario.

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http://dx.doi.org/10.1111/j.1523-1755.2004.00795.xDOI Listing
August 2004

Nitric oxide inhibits stretch-induced MAPK activation in mesangial cells through RhoA inactivation.

J Am Soc Nephrol 2003 Nov;14(11):2790-800

Department of Medicine, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/01.asn.0000094085.04161.a7DOI Listing
November 2003

Apoptotic release of histones from nucleosomes.

J Biol Chem 2002 Apr 25;277(14):12001-8. Epub 2002 Jan 25.

Department of Medicine and Department of Surgery, McMaster University, St. Joseph's Hospital, Hamilton, Ontario L8N 1Y2, Canada.

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http://dx.doi.org/10.1074/jbc.M109219200DOI Listing
April 2002

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

J Biol Chem 2002 Apr 30;277(15):12710-7. Epub 2002 Jan 30.

Department of Medicine and Father Sean O'Sullivan Research Institute, St. Joseph's Hospital and McMaster University, 708-25 Charlton Avenue, Hamilton L8N 1Y2, Canada.

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http://dx.doi.org/10.1074/jbc.M111598200DOI Listing
April 2002

Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation.

Diabetes 2002 Apr;51(4):1146-56

Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2337/diabetes.51.4.1146DOI Listing
April 2002