Damian Mole

Damian Mole

UNVERIFIED PROFILE

Are you Damian Mole?   Register this Author

Register author
Damian Mole

Damian Mole

Publications by authors named "Damian Mole"

Are you Damian Mole?   Register this Author

43Publications

652Reads

37Profile Views

Pre-, peri- and post-operative factors for the development of pancreatic fistula after pancreatic surgery.

HPB (Oxford) 2019 Jul 27. Epub 2019 Jul 27.

Clinical Surgery, University of Edinburgh, UK; Hepatobiliary and Pancreatic Surgery, Royal Infirmary of Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2019.06.004DOI Listing
July 2019

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia-reperfusion injury.

Exp Mol Med 2019 02 13;51(2):15. Epub 2019 Feb 13.

Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s12276-019-0210-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374422PMC
February 2019

Diclofenac Identified as a Kynurenine 3-Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques.

ACS Omega 2018 Mar 2;3(3):2564-2568. Epub 2018 Mar 2.

School of Biological Sciences, University of Edinburgh, The King's Buildings, Max Born Crescent, CH Waddington Building, Edinburgh, Scotland EH9 3BF, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsomega.7b02091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044753PMC
March 2018

Detecting drug-target binding in cells using fluorescence-activated cell sorting coupled with mass spectrometry analysis.

Methods Appl Fluoresc 2017 12 15;6(1):015002. Epub 2017 Dec 15.

Drug Discovery Core, University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/2050-6120/aa8c60DOI Listing
December 2017

Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct.

Diabetes Obes Metab 2017 06 28;19(6):883-891. Epub 2017 Mar 28.

Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/dom.12899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484992PMC
June 2017

Emergency general surgery 'Hot Clinics' reduce admission rates and duration of inpatient stay.

Frontline Gastroenterol 2017 Jan 14;8(1):53-61. Epub 2015 Dec 14.

Department of Clinical Surgery, School of Clinical Sciences and Community Health, The University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/flgastro-2015-100634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369429PMC
January 2017

Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Inhibition During Sepsis Dampens the Early Systemic Inflammatory Response.

Crit Care Med 2016 08;44(8):1628-9

MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000001752DOI Listing
August 2016

Lung ultrasonography as a direct measure of evolving respiratory dysfunction and disease severity in patients with acute pancreatitis.

HPB (Oxford) 2016 Feb 18;18(2):159-169. Epub 2015 Nov 18.

Clinical Surgery, School of Clinical Sciences, The University of Edinburgh, United Kingdom; MRC Centre for Inflammation Research, The University of Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hpb.2015.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814601PMC
February 2016

A magnetic bead-based ligand binding assay to facilitate human kynurenine 3-monooxygenase drug discovery.

J Biomol Screen 2015 Feb 8;20(2):292-8. Epub 2014 Oct 8.

Drug Discovery Core, University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1087057114554171DOI Listing
February 2015

Early organ dysfunction affects long-term survival in acute pancreatitis patients.

HPB (Oxford) 2014 Sep 9;16(9):789-96. Epub 2014 Apr 9.

Department of Clinical Surgery, College of Medicine and Veterinary Medicine, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/hpb.12259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159450PMC
September 2014

The intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitis.

Shock 2014 Sep;42(3):264-70

*Department of Surgery, New Jersey Medical School, Rutgers University, Newark, New Jersey; and †MRC Centre for Inflammation Research, and ‡Department of Surgery, University of Edinburgh, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SHK.0000000000000209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134397PMC
September 2014

Detailed fluid resuscitation profiles in patients with severe acute pancreatitis.

HPB (Oxford) 2011 Jan 15;13(1):51-8. Epub 2010 Nov 15.

Clinical and Surgical Sciences (Surgery), University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1477-2574.2010.00241.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019542PMC
January 2011

Discrepancy between the extent of pancreatic necrosis and multiple organ failure score in severe acute pancreatitis.

World J Surg 2009 Nov;33(11):2427-32

Clinical and Surgical Sciences (Surgery), The Royal Infirmary of Edinburgh, University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00268-009-0161-9DOI Listing
November 2009

Alcohol and global health: focus on acute pancreatitis needed.

Lancet 2009 Sep;374(9694):976-977

University of Edinburgh, Edinburgh EH16 4SA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(09)61659-7DOI Listing
September 2009

Incidence of individual organ dysfunction in fatal acute pancreatitis: analysis of 1024 death records.

HPB (Oxford) 2009 Mar;11(2):166-70

Department of Clinical and Surgical Sciences (Surgery), University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1477-2574.2009.00038.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697886PMC
March 2009

Differential preservation of lipopolysaccharide-induced chemokine/cytokine expression during experimental pancreatitis-associated organ failure in rats shows a regulatory expressed phenotype.

Pancreatology 2008 3;8(4-5):478-87. Epub 2008 Sep 3.

Clinical and Surgical Sciences (Surgery), University of Edinburgh, Edinburgh, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000151775DOI Listing
February 2009

Host matters most.

Am J Surg 2008 Sep;196(3):351-2

Clinical and Surgical Sciences (Surgery), School of Clinical Sciences and Community Health, The University of Edinburgh, Royal Infirmary, 51 Little France Crescent, Edinburgh EH16 4SA, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjsurg.2007.12.059DOI Listing
September 2008

Electronic patient data confidentiality practices among surgical trainees: questionnaire study.

Ann R Coll Surg Engl 2006 Oct;88(6):550-3

Department of Surgery, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1308/003588406X117089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963756PMC
October 2006

Diffuse coronary artery disease and dystrophic calcification of the radial artery--is there an association?

J Card Surg 2006 Jan-Feb;21(1):98-100; discussion 101

Department of Cardiac Surgery, Royal Victoria Hospital, Belfast, Northern Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1540-8191.2006.00181.xDOI Listing
May 2006

Mesenteric lymph duct ligation decreases red blood cell alterations caused by acute pancreatitis.

Am J Surg 2005 Nov;190(5):800-4

University of Medicine and Dentistry of New Jersey-New Jersey Medical School, MSB, Room G-507, 185 S. Orange Ave., Newark, NJ 07103, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjsurg.2005.07.023DOI Listing
November 2005

The isolated perfused liver response to a 'second hit' of portal endotoxin during severe acute pancreatitis.

Pancreatology 2005 28;5(4-5):475-85. Epub 2005 Jun 28.

Department of Surgery, Queen's University of Belfast, Belfast, Northern Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000086614DOI Listing
September 2005

111Indium-labelled red-cell scintigraphy to detect intermittent gastrointestinal bleeding from synchronous small- and large-bowel adenocarcinomas.

Eur J Gastroenterol Hepatol 2004 Aug;16(8):795-9

Department of Surgery and Department of Radiology, Royal Victoria Hospital, Belfast, Northern Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.meg.0000131038.92864.3bDOI Listing
August 2004

Utilizing a patent proximal vein graft stump in a case of coronary artery reoperation.

J Card Surg 2003 Jan-Feb;18(1):20-1

Department of Cardiac Surgery, Dc Royal Victoria Hospital, Belfast, Northern Ireland, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1046/j.1540-8191.2003.01905.xDOI Listing
July 2003

Delayed paraplegia after endovascular repair of abdominal aortic aneurysm.

J Vasc Surg 2003 Jun;37(6):1322-3

Vascular and Endovascular Unit, Belfast City Hospital, Belfast, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0741-5214(02)75447-5DOI Listing
June 2003

Spontaneous coronary artery dissection presenting as cardiac tamponade.

Ann Thorac Surg 2002 Apr;73(4):1324-6

Department of Cardiac Surgery, and Regional Medical Cardiology Centre, Royal Victoria Hospital, Belfast, Northern Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0003-4975(01)03240-4DOI Listing
April 2002