Damian C Genetos

Damian C Genetos

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Damian C Genetos

Publications by authors named "Damian C Genetos"

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Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects.

Bone 2018 Nov 30;116:307-314. Epub 2018 Aug 30.

Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2018.08.022DOI Listing
November 2018

Joint diseases: from connexins to gap junctions.

Nat Rev Rheumatol 2017 Dec;14(1):42-51

Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA.

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http://dx.doi.org/10.1038/nrrheum.2017.204DOI Listing
December 2017

Bone adaptation to mechanical loading in a mouse model of reduced peripheral sensory nerve function.

PLoS One 2017 31;12(10):e0187354. Epub 2017 Oct 31.

University of California Davis Medical Center, Department of Orthopaedic Surgery, Sacramento, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187354PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663494PMC
November 2017

Measurement of oxygen tension within mesenchymal stem cell spheroids.

J R Soc Interface 2017 02;14(127)

Department of Biomedical Engineering, School of Veterinary Medicine, University of California, Davis, CA 95616, USA

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http://dx.doi.org/10.1098/rsif.2016.0851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332570PMC
February 2017

Sost, independent of the non-coding enhancer ECR5, is required for bone mechanoadaptation.

Bone 2016 11 4;92:180-188. Epub 2016 Sep 4.

Department of Anatomy, Physiology and Cell Biology, University of California Davis, Davis, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.09.001DOI Listing
November 2016

Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells.

PLoS One 2014 15;9(9):e107482. Epub 2014 Sep 15.

Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107482PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164658PMC
December 2015

Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells.

Bone 2015 Dec 4;81:97-103. Epub 2015 Jul 4.

Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2015.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641015PMC
December 2015

Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice.

Arthritis Res Ther 2015 Feb 16;17:30. Epub 2015 Feb 16.

Department of Orthopaedic Surgery, University of California-Davis Medical Center, 4635 2nd Ave, Suite 2000, Sacramento, CA, 95817, USA.

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http://dx.doi.org/10.1186/s13075-015-0546-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355375PMC
February 2015

Nanocomposite scaffold for chondrocyte growth and cartilage tissue engineering: effects of carbon nanotube surface functionalization.

Tissue Eng Part A 2014 Sep 20;20(17-18):2305-15. Epub 2014 May 20.

1 Center for Autoimmune and Musculoskeletal Disease, The Feinstein Institute for Medical Research , Manhasset, New York.

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http://dx.doi.org/10.1089/ten.TEA.2013.0328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172384PMC
September 2014

Lysophosphatidic acid protects human mesenchymal stromal cells from differentiation-dependent vulnerability to apoptosis.

Tissue Eng Part A 2014 Apr 11;20(7-8):1156-64. Epub 2014 Feb 11.

1 Department of Biomedical Engineering, University of California , Davis, Davis, California.

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http://dx.doi.org/10.1089/ten.TEA.2013.0487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993074PMC
April 2014

Genomic approaches in breast cancer research.

Brief Funct Genomics 2013 Sep 20;12(5):391-6. Epub 2013 Jun 20.

Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA. Tel.: +1 530 754 0146; Fax: +1 530 753 7690;

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http://dx.doi.org/10.1093/bfgp/elt019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776566PMC
September 2013

Age-related changes in gap junctional intercellular communication in osteoblastic cells.

J Orthop Res 2012 Dec 13;30(12):1979-84. Epub 2012 Jun 13.

Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.

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http://dx.doi.org/10.1002/jor.22172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640546PMC
December 2012

Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair.

J Orthop Res 2012 Nov 16;30(11):1853-9. Epub 2012 May 16.

Department of Anatomy, Physiology, and Cell Biology, Davis, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.

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http://dx.doi.org/10.1002/jor.22145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704138PMC
November 2012

Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells.

PLoS One 2012 20;7(4):e35579. Epub 2012 Apr 20.

Department of Biomedical Engineering, University of California Davis, Davis, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035579PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334972PMC
August 2012

Targeted deletion of Sost distal enhancer increases bone formation and bone mass.

Proc Natl Acad Sci U S A 2012 Aug 10;109(35):14092-7. Epub 2012 Aug 10.

Physical and Life Sciences Directorate, Lawrence Livermore National Laboratories, Livermore, CA 94550, USA.

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http://dx.doi.org/10.1073/pnas.1207188109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435175PMC
August 2012

Ceramic identity contributes to mechanical properties and osteoblast behavior on macroporous composite scaffolds.

J Funct Biomater 2012 May 23;3(2):382-97. Epub 2012 May 23.

Department of Biomedical Engineering, University of California, Davis, CA 95616, USA.

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http://dx.doi.org/10.3390/jfb3020382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047943PMC
May 2012

TGF-β regulates sclerostin expression via the ECR5 enhancer.

Bone 2012 Mar 2;50(3):663-9. Epub 2011 Dec 2.

Biology and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, CA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S875632821101355
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http://dx.doi.org/10.1016/j.bone.2011.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278543PMC
March 2012

Modulation of osteogenic differentiation in hMSCs cells by submicron topographically-patterned ridges and grooves.

Biomaterials 2012 Jan 7;33(1):128-36. Epub 2011 Oct 7.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2011.09.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208761PMC
January 2012

Osteogenic response to BMP-2 of hMSCs grown on apatite-coated scaffolds.

Biotechnol Bioeng 2011 Nov 21;108(11):2727-35. Epub 2011 Jun 21.

Department of Biomedical Engineering, UC Davis, Davis, California 95616, USA.

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http://dx.doi.org/10.1002/bit.23227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178749PMC
November 2011

Regulation of tenascin expression in bone.

J Cell Biochem 2011 Nov;112(11):3354-63

Department of Anatomy, School of Veterinary Medicine, University of California Davis, Davis, California 95616, USA.

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http://dx.doi.org/10.1002/jcb.23265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196820PMC
November 2011

Hypoxic regulation of mesenchymal stem cell migration: the role of RhoA and HIF-1α.

Cell Biol Int 2011 Oct;35(10):981-9

Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California, Davis, U.S.A.

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http://dx.doi.org/10.1042/CBI20100733DOI Listing
October 2011

Src is sufficient, but not necessary, for osteopontin induction in osteoblasts.

Biorheology 2011 ;48(1):65-74

Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.

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http://dx.doi.org/10.3233/BIR-2011-0582DOI Listing
September 2011

Purinergic signaling is required for fluid shear stress-induced NF-κB translocation in osteoblasts.

Exp Cell Res 2011 Apr 13;317(6):737-44. Epub 2011 Jan 13.

Department of Anatomy, Cell Biology, and Physiology, School of Veterinary Medicine, University of California, Davis, CA, USA.

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http://dx.doi.org/10.1016/j.yexcr.2011.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049820PMC
April 2011

Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression.

PLoS One 2011 Mar 16;6(3):e17772. Epub 2011 Mar 16.

Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017772PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059227PMC
March 2011

Hypoxia increases Annexin A2 expression in osteoblastic cells via VEGF and ERK.

Bone 2010 Dec 15;47(6):1013-9. Epub 2010 Sep 15.

Department of Anatomy, Cell Biology, and Physiology, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA.

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http://dx.doi.org/10.1016/j.bone.2010.08.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420171PMC
December 2010

Genetic evidence that SOST inhibits WNT signaling in the limb.

Dev Biol 2010 Jun 30;342(2):169-79. Epub 2010 Mar 30.

Biology and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA.

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http://dx.doi.org/10.1016/j.ydbio.2010.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896299PMC
June 2010

The effect of oxygen tension on the long-term osteogenic differentiation and MMP/TIMP expression of human mesenchymal stem cells.

Cells Tissues Organs 2010 19;191(3):175-84. Epub 2009 Aug 19.

Department of Anatomy, University of California, Davis, 95616, USA.

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http://dx.doi.org/10.1159/000235679DOI Listing
May 2010

Oxygen tension differentially influences osteogenic differentiation of human adipose stem cells in 2D and 3D cultures.

J Cell Biochem 2010 May;110(1):87-96

Department of Biomedical Engineering, University of California, Davis, Davis, California 95616, USA.

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http://dx.doi.org/10.1002/jcb.22514DOI Listing
May 2010

Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts.

J Cell Biochem 2010 May;110(2):457-67

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, UC Davis, Davis, California 95616, USA.

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http://doi.wiley.com/10.1002/jcb.22559
Publisher Site
http://dx.doi.org/10.1002/jcb.22559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881162PMC
May 2010

Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha.

Cell Tissue Res 2010 Apr 18;340(1):81-9. Epub 2010 Feb 18.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California at Davis, 2112 Tupper Hall, Davis, CA 95616, USA.

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http://dx.doi.org/10.1007/s00441-010-0929-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847694PMC
April 2010

Prostaglandin expression profile in hypoxic osteoblastic cells.

J Bone Miner Metab 2010 28;28(1):8-16. Epub 2009 May 28.

Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, 1321 Haring Hall, One Shields Ave, Davis, CA 95616, USA.

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http://dx.doi.org/10.1007/s00774-009-0096-0DOI Listing
March 2010

Oxygen tension modulates neurite outgrowth in PC12 cells through a mechanism involving HIF and VEGF.

J Mol Neurosci 2010 Mar 27;40(3):360-6. Epub 2010 Jan 27.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA, USA.

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http://dx.doi.org/10.1007/s12031-009-9326-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825316PMC
March 2010

Modulation of sclerostin expression by mechanical loading and bone morphogenetic proteins in osteogenic cells.

Biorheology 2009 ;46(5):389-99

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California at Davis, Sacramento, CA, USA.

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http://dx.doi.org/10.3233/BIR-2009-0550DOI Listing
February 2010

Osteogenesis and trophic factor secretion are influenced by the composition of hydroxyapatite/poly(lactide-co-glycolide) composite scaffolds.

Tissue Eng Part A 2010 Jan;16(1):127-37

Department of Biomedical Engineering, University of California-Davis, Davis, California, USA.

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http://dx.doi.org/10.1089/ten.TEA.2009.0255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811060PMC
January 2010

HIF-1alpha regulates hypoxia-induced EP1 expression in osteoblastic cells.

J Cell Biochem 2009 May;107(2):233-9

Department of Surgical and Radiological Sciences, University of California at Davis, 95616, USA.

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http://dx.doi.org/10.1002/jcb.22119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410710PMC
May 2009

Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts.

Bone 2008 Apr 16;42(4):644-52. Epub 2007 Oct 16.

Department of Developmental Sciences and Orthodontics, Marquette University School of Dentistry, Milwaukee, WI, USA; Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1016/j.bone.2007.09.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937351PMC
April 2008

Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway.

Biochem Biophys Res Commun 2008 Feb 26;366(4):1061-6. Epub 2007 Dec 26.

Department of Anatomy, Physiology & Cell Biology, School of Veterinary Medicine, University of California, 4206 VM3A, 1285 Veterinary Medicine Drive, Davis, CA 95616, USA.

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http://dx.doi.org/10.1016/j.bbrc.2007.12.076DOI Listing
February 2008

DNA microarray analysis reveals a role for lysophosphatidic acid in the regulation of anti-inflammatory genes in MC3T3-E1 cells.

Bone 2007 Nov 1;41(5):833-41. Epub 2007 Aug 1.

Computational Biology and Bioinformatics Group, Pacific Northwest National Laboratory, Richland, WA 99352, USA.

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http://dx.doi.org/10.1016/j.bone.2007.06.029DOI Listing
November 2007

Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.

J Cell Physiol 2007 Jul;212(1):207-14

Department of Orthopaedic Surgery, University of California at Davis, Sacramento, California, USA.

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http://dx.doi.org/10.1002/jcp.21021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929812PMC
July 2007

Hypoxia regulates PGE(2) release and EP1 receptor expression in osteoblastic cells.

J Cell Physiol 2007 Jul;212(1):182-8

Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California at Davis, Davis, California 95616, USA.

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http://dx.doi.org/10.1002/jcp.21017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929130PMC
July 2007

MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation.

Am J Physiol Cell Physiol 2006 Mar 2;290(3):C776-84. Epub 2005 Nov 2.

Department of Orthopaedics and Rehabilitation, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Ctr., Hershey, PA 17033, USA.

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http://dx.doi.org/10.1152/ajpcell.00082.2005DOI Listing
March 2006

Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts.

J Bone Miner Res 2005 Jan 18;20(1):41-9. Epub 2004 Oct 18.

Departments of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.

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http://dx.doi.org/10.1359/JBMR.041009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929123PMC
January 2005

Fluid shear-induced NFkappaB translocation in osteoblasts is mediated by intracellular calcium release.

Bone 2003 Sep;33(3):399-410

Department of Anatomy, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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September 2003