Publications by authors named "Daeyoup Lee"

55Publications

Dynamic modules of the coactivator SAGA in eukaryotic transcription.

Exp Mol Med 2020 Jul 3;52(7):991-1003. Epub 2020 Jul 3.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.

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http://dx.doi.org/10.1038/s12276-020-0463-4DOI Listing
July 2020

Nuclear aconitase antagonizes heterochromatic silencing by interfering with Chp1 binding to DNA.

Biochem Biophys Res Commun 2019 08 27;516(3):806-811. Epub 2019 Jun 27.

School of Biological Sciences, Institute of Microbiology, Seoul National University, Seoul, 151-742, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.06.090DOI Listing
August 2019

SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis.

Nat Commun 2019 06 5;10(1):2458. Epub 2019 Jun 5.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.

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http://dx.doi.org/10.1038/s41467-019-10350-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549176PMC
June 2019

Pro-angiogenic Ginsenosides F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1.

Sci Rep 2019 03 14;9(1):4502. Epub 2019 Mar 14.

Biomedical Science and Engineering Interdisciplinary Program, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Korea.

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http://dx.doi.org/10.1038/s41598-019-41115-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418182PMC
March 2019

Polymer Thin Film-Induced Tumor Spheroids Acquire Cancer Stem Cell-like Properties.

Cancer Res 2018 12 23;78(24):6890-6902. Epub 2018 Oct 23.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-0927DOI Listing
December 2018

BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors.

Nat Med 2018 11 17;24(11):1662-1668. Epub 2018 Sep 17.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

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http://www.nature.com/articles/s41591-018-0172-x
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http://dx.doi.org/10.1038/s41591-018-0172-xDOI Listing
November 2018

Chd1p recognizes H3K36Ac to maintain nucleosome positioning near the transcription start site.

Biochem Biophys Res Commun 2018 09 11;503(3):1200-1206. Epub 2018 Jul 11.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.07.025DOI Listing
September 2018

Gene-targeted Random Mutagenesis to Select Heterochromatin-destabilizing Proteasome Mutants in Fission Yeast.

J Vis Exp 2018 05 15(135). Epub 2018 May 15.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology.

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http://dx.doi.org/10.3791/57499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101219PMC
May 2018

Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast.

Nat Commun 2018 01 16;9(1):240. Epub 2018 Jan 16.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.

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http://dx.doi.org/10.1038/s41467-017-02759-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770421PMC
January 2018

The 19S proteasome regulates subtelomere silencing and facultative heterochromatin formation in fission yeast.

Curr Genet 2018 Jun 6;64(3):741-752. Epub 2017 Dec 6.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.

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http://dx.doi.org/10.1007/s00294-017-0792-6DOI Listing
June 2018

It's fun to transcribe with Fun30: A model for nucleosome dynamics during RNA polymerase II-mediated elongation.

Transcription 2018 4;9(2):108-116. Epub 2017 Oct 4.

a Department of Biological Sciences , Korea Advanced Institute of Science and Technology , Daejeon , South Korea.

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http://dx.doi.org/10.1080/21541264.2017.1356434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834224PMC
November 2018

The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3.

Nat Commun 2017 09 13;8(1):529. Epub 2017 Sep 13.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.

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http://www.nature.com/articles/s41467-017-00704-3
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http://dx.doi.org/10.1038/s41467-017-00704-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597579PMC
September 2017

The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast.

J Biol Chem 2017 10 7;292(41):17144-17155. Epub 2017 Aug 7.

From the Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea,

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http://dx.doi.org/10.1074/jbc.M117.790824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641893PMC
October 2017

Structural Insight into the Critical Role of the N-Terminal Region in the Catalytic Activity of Dual-Specificity Phosphatase 26.

PLoS One 2016 1;11(9):e0162115. Epub 2016 Sep 1.

Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162115PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008780PMC
August 2017

Both H4K20 mono-methylation and H3K56 acetylation mark transcription-dependent histone turnover in fission yeast.

Biochem Biophys Res Commun 2016 08 3;476(4):515-521. Epub 2016 Jun 3.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.05.155DOI Listing
August 2016

A basal-like breast cancer-specific role for SRF-IL6 in YAP-induced cancer stemness.

Nat Commun 2015 Dec 16;6:10186. Epub 2015 Dec 16.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1038/ncomms10186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703869PMC
December 2015

Biogenesis and regulation of the let-7 miRNAs and their functional implications.

Protein Cell 2016 Feb 23;7(2):100-13. Epub 2015 Sep 23.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea.

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http://dx.doi.org/10.1007/s13238-015-0212-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742387PMC
February 2016

Essential function of Aco2, a fusion protein of aconitase and mitochondrial ribosomal protein bL21, in mitochondrial translation in fission yeast.

FEBS Lett 2015 Mar 25;589(7):822-8. Epub 2015 Feb 25.

School of Biological Sciences, and Institute of Microbiology, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.02.015DOI Listing
March 2015

SET7/9 methylation of the pluripotency factor LIN28A is a nucleolar localization mechanism that blocks let-7 biogenesis in human ESCs.

Cell Stem Cell 2014 Dec;15(6):735-49

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258232PMC
December 2014

A histone methyltransferase inhibits seed germination by increasing PIF1 mRNA expression in imbibed seeds.

Plant J 2014 Apr 26;78(2):282-93. Epub 2014 Mar 26.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea.

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http://dx.doi.org/10.1111/tpj.12467DOI Listing
April 2014

Separation of a functional deubiquitylating module from the SAGA complex by the proteasome regulatory particle.

Nat Commun 2013 ;4:2641

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1038/ncomms3641DOI Listing
May 2014

Gender-specific metabolomic profiling of obesity in leptin-deficient ob/ob mice by 1H NMR spectroscopy.

PLoS One 2013 3;8(10):e75998. Epub 2013 Oct 3.

Medical Proteomics Research Center, KRIBB, Daejeon, Republic of Korea ; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075998PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789719PMC
June 2014

Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage.

Hum Mol Genet 2014 Feb 18;23(3):657-67. Epub 2013 Sep 18.

Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Korea.

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http://dx.doi.org/10.1093/hmg/ddt453DOI Listing
February 2014

High-resolution crystal structure of the catalytic domain of human dual-specificity phosphatase 26.

Acta Crystallogr D Biol Crystallogr 2013 Jun 16;69(Pt 6):1160-70. Epub 2013 May 16.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.

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http://dx.doi.org/10.1107/S0907444913004770DOI Listing
June 2013

A facile strategy for selective incorporation of phosphoserine into histones.

Angew Chem Int Ed Engl 2013 May 26;52(22):5771-5. Epub 2013 Mar 26.

Department of Chemistry, Korea Advanced Institute of Science and Technology, 335 Gwahak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea.

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http://dx.doi.org/10.1002/anie.201300531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775851PMC
May 2013

Human histone H3K79 methyltransferase DOT1L protein [corrected] binds actively transcribing RNA polymerase II to regulate gene expression.

J Biol Chem 2012 Nov 25;287(47):39698-709. Epub 2012 Sep 25.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1074/jbc.M112.384057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501035PMC
November 2012

Hrp3 controls nucleosome positioning to suppress non-coding transcription in eu- and heterochromatin.

EMBO J 2012 Nov 18;31(23):4375-87. Epub 2012 Sep 18.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

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http://emboj.embopress.org/cgi/doi/10.1038/emboj.2012.267
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http://dx.doi.org/10.1038/emboj.2012.267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512395PMC
November 2012

Human papillomavirus type 16 E6 protein inhibits DNA fragmentation via interaction with DNA fragmentation factor 40.

Cancer Lett 2012 Nov 17;324(1):109-17. Epub 2012 May 17.

Department of Life Science, Dongguk University-Seoul, Seoul 100-715, Republic of Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835120030
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http://dx.doi.org/10.1016/j.canlet.2012.05.010DOI Listing
November 2012

H2B monoubiquitylation is a 5'-enriched active transcription mark and correlates with exon-intron structure in human cells.

Genome Res 2012 Jun 15;22(6):1026-35. Epub 2012 Mar 15.

Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Yuseong-gu, Daejeon, Korea;

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http://dx.doi.org/10.1101/gr.120634.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371706PMC
June 2012

Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes.

Nucleic Acids Res 2012 May 8;40(10):4461-72. Epub 2012 Feb 8.

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gks056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378893PMC
May 2012

Decoding the genome with an integrative analysis tool: combinatorial CRM Decoder.

Nucleic Acids Res 2011 Sep 30;39(17):e116. Epub 2011 Jun 30.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.

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http://dx.doi.org/10.1093/nar/gkr516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177223PMC
September 2011

Identification of DNA methylation markers for lineage commitment of in vitro hepatogenesis.

Hum Mol Genet 2011 Jul 19;20(14):2722-33. Epub 2011 Apr 19.

1Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.

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http://dx.doi.org/10.1093/hmg/ddr171DOI Listing
July 2011

The proteasome and its regulatory roles in gene expression.

Biochim Biophys Acta 2011 Feb 17;1809(2):88-96. Epub 2010 Aug 17.

Department of Biological Sciences, KAIST, Yuseong-Gu, Daejeon, 305-701, Korea.

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http://dx.doi.org/10.1016/j.bbagrm.2010.08.001DOI Listing
February 2011

A lysine-rich region in Dot1p is crucial for direct interaction with H2B ubiquitylation and high level methylation of H3K79.

Biochem Biophys Res Commun 2010 Sep 3;399(4):512-7. Epub 2010 Aug 3.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 335 Gwahak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2010.07.100DOI Listing
September 2010

The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination.

J Biol Chem 2010 Jun 30;285(23):17754-62. Epub 2010 Mar 30.

Division of Magnetic Resonance, Korea Basic Science Institute Ochang Campus, Cheongwon-Gun, Ochang-Eup, Yangcheong-Ri 804-1, Chungcheongbuk-Do 363-883, South Korea.

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http://dx.doi.org/10.1074/jbc.M109.090621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878539PMC
June 2010

Histone occupancy-dependent and -independent removal of H3K27 trimethylation at cold-responsive genes in Arabidopsis.

Plant J 2009 Oct 28;60(1):112-21. Epub 2009 May 28.

Department of Biological Sciences, KAIST, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1111/j.1365-313X.2009.03938.xDOI Listing
October 2009

Arabidopsis ING and Alfin1-like protein families localize to the nucleus and bind to H3K4me3/2 via plant homeodomain fingers.

Plant J 2009 May 18;58(3):511-24. Epub 2009 Jan 18.

Department of Biological Sciences, KAIST, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1111/j.1365-313X.2009.03795.xDOI Listing
May 2009

Combined action of PHD and chromo domains directs the Rpd3S HDAC to transcribed chromatin.

Science 2007 May;316(5827):1050-4

Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.

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http://dx.doi.org/10.1126/science.1139004DOI Listing
May 2007

Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling.

Proc Natl Acad Sci U S A 2005 Dec 12;102(51):18385-90. Epub 2005 Dec 12.

Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.

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http://dx.doi.org/10.1073/pnas.0507975102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1317944PMC
December 2005

The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.

Cell 2005 Nov;123(3):423-36

Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, Missouri 64110, USA.

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http://dx.doi.org/10.1016/j.cell.2005.08.015DOI Listing
November 2005

BRCA1 associates with human papillomavirus type 18 E2 and stimulates E2-dependent transcription.

Biochem Biophys Res Commun 2003 Jun;305(4):1008-16

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Republic of Korea.

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http://dx.doi.org/10.1016/s0006-291x(03)00880-5DOI Listing
June 2003

Kaposi's sarcoma-associated herpesvirus K8 protein interacts with hSNF5.

J Gen Virol 2003 Mar;84(Pt 3):665-676

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1099/vir.0.18699-0DOI Listing
March 2003

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus functionally interacts with heterochromatin protein 1.

J Biol Chem 2003 Feb 16;278(9):7397-405. Epub 2002 Dec 16.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1074/jbc.M211912200DOI Listing
February 2003

The viral oncogene human papillomavirus E7 deregulates transcriptional silencing by Brm-related gene 1 via molecular interactions.

J Biol Chem 2002 Dec 7;277(50):48842-8. Epub 2002 Oct 7.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1074/jbc.M203583200DOI Listing
December 2002

Functional interaction between human papillomavirus type 18 E2 and poly(ADP-ribose) polymerase 1.

Oncogene 2002 Aug;21(38):5877-85

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1038/sj.onc.1205723DOI Listing
August 2002

Human papillomavirus E2 down-regulates the human telomerase reverse transcriptase promoter.

J Biol Chem 2002 Aug 17;277(31):27748-56. Epub 2002 May 17.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1074/jbc.M203706200DOI Listing
August 2002

SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription.

J Biol Chem 2002 Jun 11;277(25):22330-7. Epub 2002 Apr 11.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111987200
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http://dx.doi.org/10.1074/jbc.M111987200DOI Listing
June 2002

Functional interaction between p/CAF and human papillomavirus E2 protein.

J Biol Chem 2002 Feb 14;277(8):6483-9. Epub 2001 Dec 14.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1074/jbc.M105085200DOI Listing
February 2002

Human papillomavirus type 16 E7 binds to E2F1 and activates E2F1-driven transcription in a retinoblastoma protein-independent manner.

J Biol Chem 2002 Jan 16;277(4):2923-30. Epub 2001 Nov 16.

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea.

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http://dx.doi.org/10.1074/jbc.M109113200DOI Listing
January 2002