Publications by authors named "Dadi Jiang"

23 Publications

  • Page 1 of 1

ATR inhibition potentiates ionizing radiation-induced interferon response via cytosolic nucleic acid-sensing pathways.

Authors:
Xu Feng Anthony Tubbs Chunchao Zhang Mengfan Tang Sriram Sridharan Chao Wang Dadi Jiang Dan Su Huimin Zhang Zhen Chen Litong Nie Yun Xiong Min Huang André Nussenzweig Junjie Chen

EMBO J 2020 Jul 2;39(14):e104036. Epub 2020 Jun 2.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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July 2020

Induced Tumor Heterogeneity Reveals Factors Informing Radiation and Immunotherapy Combinations.

Authors:
Todd A Aguilera Eslam A Elghonaimy Hussein Shehade Marjan Rafat Laura Castellini Dadi Jiang Mihalis Kariolis Albert C Koong Quynh-Thu Le Lesley G Ellies Erinn B Rankin Edward E Graves Amato J Giaccia

Clin Cancer Res 2020 06 25;26(12):2972-2985. Epub 2020 Feb 25.

Department of Radiation Oncology, Stanford University, Stanford, California.

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June 2020

Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.

Authors:
Dhanya K Nambiar Todd Aguilera Hongbin Cao Shirley Kwok Christina Kong Joshua Bloomstein Zemin Wang Vangipuram S Rangan Dadi Jiang Rie von Eyben Rachel Liang Sonya Agarwal A Dimitrios Colevas Alan Korman Clint T Allen Ravindra Uppaluri Albert C Koong Amato Giaccia Quynh Thu Le

J Clin Invest 2019 12;129(12):5553-5567

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA.

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December 2019

Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO-AACR Research Workshop.

Authors:
Heather M McGee Dadi Jiang David R Soto-Pantoja Avinoam Nevler Amato J Giaccia Wendy A Woodward

Clin Cancer Res 2019 05 5;25(10):2969-2974. Epub 2019 Feb 5.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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May 2019

Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes.

Authors:
Julie P Saiki Hongbin Cao Lauren D Van Wassenhove Vignesh Viswanathan Joshua Bloomstein Dhanya K Nambiar Aaron J Mattingly Dadi Jiang Che-Hong Chen Matthew C Stevens Amanda L Simmons Hyun Shin Park Rie von Eyben Eric T Kool Davud Sirjani Sarah M Knox Quynh Thu Le Daria Mochly-Rosen

Proc Natl Acad Sci U S A 2018 06 24;115(24):6279-6284. Epub 2018 May 24.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305;

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June 2018

A Human Genome-Wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1α-XBP1 Activation.

Authors:
Zhifen Yang Jing Zhang Dadi Jiang Purvesh Khatri David E Solow-Cordero Diego A S Toesca Constantinos Koumenis Nicholas C Denko Amato J Giaccia Quynh-Thu Le Albert C Koong

Mol Cancer Res 2018 05 9;16(5):745-753. Epub 2018 Feb 9.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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May 2018

Inhibition of IRE1 results in decreased scar formation.

Authors:
Tatiana V Boyko Rakesh Bam Dadi Jiang Zhen Wang Namrata Bhatia Misha C Tran Michael T Longaker Albert C Koong George P Yang

Wound Repair Regen 2017 11 6;25(6):964-971. Epub 2018 Feb 6.

Department of Surgery, Stanford University School of Medicine, Stanford, California.

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November 2017

Chemical Space Mimicry for Drug Discovery.

Authors:
William Yuan Dadi Jiang Dhanya K Nambiar Lydia P Liew Michael P Hay Joshua Bloomstein Peter Lu Brandon Turner Quynh-Thu Le Robert Tibshirani Purvesh Khatri Mark G Moloney Albert C Koong

J Chem Inf Model 2017 04 3;57(4):875-882. Epub 2017 Apr 3.

Department of Radiation Oncology, Stanford University School of Medicine , Stanford, California 94305, United States.

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April 2017

Comprehensive Analysis of the Unfolded Protein Response in Breast Cancer Subtypes.

Authors:
Dadi Jiang Brandon Turner Jie Song Ruijiang Li Maximilian Diehn Quynh-Thu Le Purvesh Khatri Albert C Koong

JCO Precis Oncol 2017 26;2017. Epub 2017 Jul 26.

Stanford University School of Medicine, Stanford, CA.

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July 2017

Reprogramming the immunological microenvironment through radiation and targeting Axl.

Authors:
Todd A Aguilera Marjan Rafat Laura Castellini Hussein Shehade Mihalis S Kariolis Angela Bik-Yu Hui Henning Stehr Rie von Eyben Dadi Jiang Lesley G Ellies Albert C Koong Maximilian Diehn Erinn B Rankin Edward E Graves Amato J Giaccia

Nat Commun 2016 12 23;7:13898. Epub 2016 Dec 23.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, 269 Campus Drive, Stanford University, Stanford, California 94305, USA.

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December 2016

Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.

Authors:
Mihalis S Kariolis Yu Rebecca Miao Anh Diep Shannon E Nash Monica M Olcina Dadi Jiang Douglas S Jones Shiven Kapur Irimpan I Mathews Albert C Koong Erinn B Rankin Jennifer R Cochran Amato J Giaccia

J Clin Invest 2017 01 28;127(1):183-198. Epub 2016 Nov 28.

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January 2017

Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.

Authors:
Dadi Jiang Connor Lynch Bruno C Medeiros Michaela Liedtke Rakesh Bam Arvin B Tam Zhifen Yang Muthuraman Alagappan Parveen Abidi Quynh-Thu Le Amato J Giaccia Nicholas C Denko Maho Niwa Albert C Koong

Sci Rep 2016 09 16;6:33353. Epub 2016 Sep 16.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 USA.

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September 2016

A Multimodal Data Analysis Approach for Targeted Drug Discovery Involving Topological Data Analysis (TDA).

Authors:
Muthuraman Alagappan Dadi Jiang Nicholas Denko Albert C Koong

Adv Exp Med Biol 2016;899:253-68

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.

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June 2017

Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.

Authors:
Dadi Jiang Arvin B Tam Muthuraman Alagappan Michael P Hay Aparna Gupta Margaret M Kozak David E Solow-Cordero Pek Y Lum Nicholas C Denko Amato J Giaccia Quynh-Thu Le Maho Niwa Albert C Koong

Mol Cancer Ther 2016 09 15;15(9):2055-65. Epub 2016 Jun 15.

Department of Radiation Oncology, Stanford University, Stanford, California.

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September 2016

Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.

Authors:
Dadi Jiang Maho Niwa Albert C Koong

Semin Cancer Biol 2015 Aug 16;33:48-56. Epub 2015 May 16.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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August 2015

Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells.

Authors:
Elizabeth C Finger Laura Castellini Erinn B Rankin Marta Vilalta Adam J Krieg Dadi Jiang Alice Banh Wayne Zundel Marianne Broome Powell Amato J Giaccia

Proc Natl Acad Sci U S A 2015 Apr 19;112(14):4441-6. Epub 2015 Mar 19.

Department of Radiation Oncology, Stanford University, Stanford, CA 94305;

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April 2015

Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.

Authors:
Dadi Jiang Edward L LaGory Daniela Kenzelmann Brož Kathryn T Bieging Colleen A Brady Nichole Link John M Abrams Amato J Giaccia Laura D Attardi

Cell Rep 2015 Feb 19;10(7):1096-109. Epub 2015 Feb 19.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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February 2015

Comparison of effects of p53 null and gain-of-function mutations on salivary tumors in MMTV-Hras transgenic mice.

Authors:
Dadi Jiang Catherine I Dumur H Davis Massey Viswanathan Ramakrishnan Mark A Subler Jolene J Windle

PLoS One 2015 19;10(2):e0118029. Epub 2015 Feb 19.

Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America; Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.

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January 2016

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses.

Authors:
Daniela Kenzelmann Broz Stephano Spano Mello Kathryn T Bieging Dadi Jiang Rachel L Dusek Colleen A Brady Arend Sidow Laura D Attardi

Genes Dev 2013 May;27(9):1016-31

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.

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May 2013

Engaging the p53 metabolic brake drives senescence.

Authors:
Dadi Jiang Laura D Attardi

Cell Res 2013 Jun 12;23(6):739-40. Epub 2013 Mar 12.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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June 2013

Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages.

Authors:
Dadi Jiang Colleen A Brady Thomas M Johnson Eunice Y Lee Eunice J Park Matthew P Scott Laura D Attardi

Proc Natl Acad Sci U S A 2011 Oct 3;108(41):17123-8. Epub 2011 Oct 3.

Department of Radiation Oncology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

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October 2011

Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.

Authors:
Colleen A Brady Dadi Jiang Stephano S Mello Thomas M Johnson Lesley A Jarvis Margaret M Kozak Daniela Kenzelmann Broz Shashwati Basak Eunice J Park Margaret E McLaughlin Anthony N Karnezis Laura D Attardi

Cell 2011 May;145(4):571-83

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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May 2011

Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.

Authors:
Veronica G Beaudry Dadi Jiang Rachel L Dusek Eunice J Park Stevan Knezevich Katie Ridd Hannes Vogel Boris C Bastian Laura D Attardi

PLoS Genet 2010 Oct 21;6(10):e1001168. Epub 2010 Oct 21.

Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University School of Medicine, Stanford, California, USA.

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October 2010