Dadi Jiang

Dadi Jiang

UNVERIFIED PROFILE

Are you Dadi Jiang?   Register this Author

Register author
Dadi Jiang

Dadi Jiang

Publications by authors named "Dadi Jiang"

Are you Dadi Jiang?   Register this Author

21Publications

494Reads

24Profile Views

Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.

Authors:
Dhanya K Nambiar Todd Aguilera Hongbin Cao Shirley Kwok Christina Kong Joshua Bloomstein Zemin Wang Vangipuram S Rangan Dadi Jiang Rie von Eyben Rachel Liang Sonya Agarwal A Dimitrios Colevas Alan Korman Clint T Allen Ravindra Uppaluri Albert C Koong Amato Giaccia Quynh Thu Le

J Clin Invest 2019 Dec;129(12):5553-5567

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1172/JCI129025DOI Listing
December 2019

Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO-AACR Research Workshop.

Authors:
Heather M McGee Dadi Jiang David R Soto-Pantoja Avinoam Nevler Amato J Giaccia Wendy A Woodward

Clin Cancer Res 2019 05 5;25(10):2969-2974. Epub 2019 Feb 5.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1158/1078-0432.CCR-18-3781DOI Listing
May 2019

Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes.

Authors:
Julie P Saiki Hongbin Cao Lauren D Van Wassenhove Vignesh Viswanathan Joshua Bloomstein Dhanya K Nambiar Aaron J Mattingly Dadi Jiang Che-Hong Chen Matthew C Stevens Amanda L Simmons Hyun Shin Park Rie von Eyben Eric T Kool Davud Sirjani Sarah M Knox Quynh Thu Le Daria Mochly-Rosen

Proc Natl Acad Sci U S A 2018 06 24;115(24):6279-6284. Epub 2018 May 24.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305;

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1073/pnas.1802184115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004437PMC
June 2018

A Human Genome-Wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1α-XBP1 Activation.

Authors:
Zhifen Yang Jing Zhang Dadi Jiang Purvesh Khatri David E Solow-Cordero Diego A S Toesca Constantinos Koumenis Nicholas C Denko Amato J Giaccia Quynh-Thu Le Albert C Koong

Mol Cancer Res 2018 05 9;16(5):745-753. Epub 2018 Feb 9.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1158/1541-7786.MCR-17-0307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932228PMC
May 2018

Inhibition of IRE1 results in decreased scar formation.

Authors:
Tatiana V Boyko Rakesh Bam Dadi Jiang Zhen Wang Namrata Bhatia Misha C Tran Michael T Longaker Albert C Koong George P Yang

Wound Repair Regen 2017 11 6;25(6):964-971. Epub 2018 Feb 6.

Department of Surgery, Stanford University School of Medicine, Stanford, California.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1111/wrr.12603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854534PMC
November 2017

Comprehensive Analysis of the Unfolded Protein Response in Breast Cancer Subtypes.

Authors:
Dadi Jiang Brandon Turner Jie Song Ruijiang Li Maximilian Diehn Quynh-Thu Le Purvesh Khatri Albert C Koong

JCO Precis Oncol 2017 26;2017. Epub 2017 Jul 26.

Stanford University School of Medicine, Stanford, CA.

View Article

Download full-text PDF

 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992919PMC
http://dx.doi.org/10.1200/PO.16.00073DOI Listing
July 2017

A Multimodal Data Analysis Approach for Targeted Drug Discovery Involving Topological Data Analysis (TDA).

Authors:
Muthuraman Alagappan Dadi Jiang Nicholas Denko Albert C Koong

Adv Exp Med Biol 2016;899:253-68

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1007/978-3-319-26666-4_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519345PMC
June 2017

Chemical Space Mimicry for Drug Discovery.

Authors:
William Yuan Dadi Jiang Dhanya K Nambiar Lydia P Liew Michael P Hay Joshua Bloomstein Peter Lu Brandon Turner Quynh-Thu Le Robert Tibshirani Purvesh Khatri Mark G Moloney Albert C Koong

J Chem Inf Model 2017 04 3;57(4):875-882. Epub 2017 Apr 3.

Department of Radiation Oncology, Stanford University School of Medicine , Stanford, California 94305, United States.

View Article

Download full-text PDF

 Source
http://pubs.acs.org/doi/10.1021/acs.jcim.6b00754
Publisher Site
http://dx.doi.org/10.1021/acs.jcim.6b00754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802964PMC
April 2017

Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.

Authors:
Mihalis S Kariolis Yu Rebecca Miao Anh Diep Shannon E Nash Monica M Olcina Dadi Jiang Douglas S Jones Shiven Kapur Irimpan I Mathews Albert C Koong Erinn B Rankin Jennifer R Cochran Amato J Giaccia

J Clin Invest 2017 01 28;127(1):183-198. Epub 2016 Nov 28.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1172/JCI85610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199716PMC
January 2017

Reprogramming the immunological microenvironment through radiation and targeting Axl.

Authors:
Todd A Aguilera Marjan Rafat Laura Castellini Hussein Shehade Mihalis S Kariolis Angela Bik-Yu Hui Henning Stehr Rie von Eyben Dadi Jiang Lesley G Ellies Albert C Koong Maximilian Diehn Erinn B Rankin Edward E Graves Amato J Giaccia

Nat Commun 2016 12 23;7:13898. Epub 2016 Dec 23.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, 269 Campus Drive, Stanford University, Stanford, California 94305, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/ncomms13898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196438PMC
December 2016

Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.

Authors:
Dadi Jiang Arvin B Tam Muthuraman Alagappan Michael P Hay Aparna Gupta Margaret M Kozak David E Solow-Cordero Pek Y Lum Nicholas C Denko Amato J Giaccia Quynh-Thu Le Maho Niwa Albert C Koong

Mol Cancer Ther 2016 09 15;15(9):2055-65. Epub 2016 Jun 15.

Department of Radiation Oncology, Stanford University, Stanford, California.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1158/1535-7163.MCT-15-1023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010920PMC
September 2016

Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.

Authors:
Dadi Jiang Connor Lynch Bruno C Medeiros Michaela Liedtke Rakesh Bam Arvin B Tam Zhifen Yang Muthuraman Alagappan Parveen Abidi Quynh-Thu Le Amato J Giaccia Nicholas C Denko Maho Niwa Albert C Koong

Sci Rep 2016 09 16;6:33353. Epub 2016 Sep 16.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/srep33353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025885PMC
September 2016

Comparison of effects of p53 null and gain-of-function mutations on salivary tumors in MMTV-Hras transgenic mice.

Authors:
Dadi Jiang Catherine I Dumur H Davis Massey Viswanathan Ramakrishnan Mark A Subler Jolene J Windle

PLoS One 2015 19;10(2):e0118029. Epub 2015 Feb 19.

Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America; Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America.

View Article

Download full-text PDF

 Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118029PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335025PMC
January 2016

Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.

Authors:
Dadi Jiang Maho Niwa Albert C Koong

Semin Cancer Biol 2015 Aug 16;33:48-56. Epub 2015 May 16.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.semcancer.2015.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523453PMC
August 2015

Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells.

Authors:
Elizabeth C Finger Laura Castellini Erinn B Rankin Marta Vilalta Adam J Krieg Dadi Jiang Alice Banh Wayne Zundel Marianne Broome Powell Amato J Giaccia

Proc Natl Acad Sci U S A 2015 Apr 19;112(14):4441-6. Epub 2015 Mar 19.

Department of Radiation Oncology, Stanford University, Stanford, CA 94305;

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1073/pnas.1418164112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394282PMC
April 2015

Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.

Authors:
Dadi Jiang Edward L LaGory Daniela Kenzelmann Brož Kathryn T Bieging Colleen A Brady Nichole Link John M Abrams Amato J Giaccia Laura D Attardi

Cell Rep 2015 Feb 19;10(7):1096-109. Epub 2015 Feb 19.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.celrep.2015.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365998PMC
February 2015

Engaging the p53 metabolic brake drives senescence.

Authors:
Dadi Jiang Laura D Attardi

Cell Res 2013 Jun 12;23(6):739-40. Epub 2013 Mar 12.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1038/cr.2013.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674383PMC
June 2013

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses.

Authors:
Daniela Kenzelmann Broz Stephano Spano Mello Kathryn T Bieging Dadi Jiang Rachel L Dusek Colleen A Brady Arend Sidow Laura D Attardi

Genes Dev 2013 May;27(9):1016-31

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1101/gad.212282.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3656320PMC
May 2013

Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages.

Authors:
Dadi Jiang Colleen A Brady Thomas M Johnson Eunice Y Lee Eunice J Park Matthew P Scott Laura D Attardi

Proc Natl Acad Sci U S A 2011 Oct 3;108(41):17123-8. Epub 2011 Oct 3.

Department of Radiation Oncology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

 Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1111245108
Publisher Site
http://dx.doi.org/10.1073/pnas.1111245108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193184PMC
October 2011

Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.

Authors:
Colleen A Brady Dadi Jiang Stephano S Mello Thomas M Johnson Lesley A Jarvis Margaret M Kozak Daniela Kenzelmann Broz Shashwati Basak Eunice J Park Margaret E McLaughlin Anthony N Karnezis Laura D Attardi

Cell 2011 May;145(4):571-83

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1016/j.cell.2011.03.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259909PMC
May 2011

Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.

Authors:
Veronica G Beaudry Dadi Jiang Rachel L Dusek Eunice J Park Stevan Knezevich Katie Ridd Hannes Vogel Boris C Bastian Laura D Attardi

PLoS Genet 2010 Oct 21;6(10):e1001168. Epub 2010 Oct 21.

Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University School of Medicine, Stanford, California, USA.

View Article

Download full-text PDF

 Source
http://dx.doi.org/10.1371/journal.pgen.1001168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958815PMC
October 2010