DaChuan Huang

DaChuan Huang

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DaChuan Huang

DaChuan Huang

Publications by authors named "DaChuan Huang"

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28Publications

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Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein.

Nat Commun 2017 06 28;8:15866. Epub 2017 Jun 28.

Center for Cancer Research, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts 02139, USA.

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http://dx.doi.org/10.1038/ncomms15866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493755PMC
June 2017

Effect of Ang-2-VEGF-A Bispecific Antibody in Renal Cell Carcinoma.

Cancer Invest 2015 26;33(8):378-86. Epub 2015 Jun 26.

a Laboratory of Cancer Epigenome , National Cancer Centre Singapore , Singapore.

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http://dx.doi.org/10.3109/07357907.2015.1047505DOI Listing
April 2016

Fumarate Hydratase-deficient Cell Line NCCFH1 as a New In Vitro Model of Hereditary Papillary Renal Cell Carcinoma Type 2.

Anticancer Res 2015 Dec;35(12):6639-53

Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Republic of Singapore Division of Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Republic of Singapore

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December 2015

Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.

Gut 2015 May 22;64(5):707-19. Epub 2014 Jul 22.

Cancer and Stem Cell Biology program, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore Cellular and Molecular Research, National Cancer Centre, Singapore, Singapore Genome Institute of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1136/gutjnl-2013-306596DOI Listing
May 2015

Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.

J Clin Endocrinol Metab 2015 Feb 11;100(2):E360-4. Epub 2014 Nov 11.

Laboratory of Cancer Epigenome (W.Y., H.L.H., A.G., D.H., S.L.P., C.K.O., B.T.T.), Division of Medical Sciences, National Cancer Centre Singapore, 169610 Singapore; Division of Cancer and Stem Cell Biology (W.Y., J.R.M., H.L.H., D.H., S.L.P., C.K.O., S.G.R., P.T., B.T.T.), Duke-National University of Singapore Graduate Medical School, 169857 Singapore; National University of Singapore Graduate School for Integrative Sciences and Engineering (W.Y.), 117456 Singapore; Academic Endocrine Unit, Nuffield Department of Clinical Medicine (M.S., P.N., R.V.T.), Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, OX3 7LJ Oxford, United Kingdom; Department of Pathology (R.v.E., D.R., T.v.W., H.M.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Molecular Endocrinology Group, Molecular Pathobiology Research Centre Unit (U.I.P.M.) (B.C.) of the Portuguese Institute of Oncology from Lisbon Francisco Gentil (IPOLFG) and Chronic Diseases Research Centre (CEDOC), Faculty of Medical Sciences (FCM), New University of Lisbon (UNL), 1099-023 Lisbon, Portugal; Genome Institute of Singapore (P.T.), 138672 Singapore; and Cancer Science Institute of Singapore (P.T., B.T.T.), National University of Singapore, 117599 Singapore.

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http://dx.doi.org/10.1210/jc.2014-3238DOI Listing
February 2015

Inhibition of placental growth factor in renal cell carcinoma.

Anticancer Res 2015 Jan;35(1):531-41

Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.

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January 2015

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers.

Nat Genet 2013 Dec 3;45(12):1474-8. Epub 2013 Nov 3.

1] Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore. [2] Division of Cancer and Stem Cell Biology, Duke-National University of Singapore Graduate Medical School, Singapore. [3] Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. [4].

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http://www.nature.com/articles/ng.2806
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http://dx.doi.org/10.1038/ng.2806DOI Listing
December 2013

Expression of the PTTG1 oncogene is associated with aggressive clear cell renal cell carcinoma.

Cancer Res 2012 Sep 17;72(17):4361-71. Epub 2012 Jul 17.

Laboratories of Cancer Genetics, Cytogenetics, and Computational Biology, Van Andel Research Institute; Department of Urology, Spectrum Health Hospital, Grand Rapids, MI 49503, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-11-2330DOI Listing
September 2012

SNX3-dependent regulation of epidermal growth factor receptor (EGFR) trafficking and degradation by aspirin in epidermoid carcinoma (A-431) cells.

Cell Mol Life Sci 2012 May 11;69(9):1505-21. Epub 2011 Dec 11.

Laboratory of Membrane Trafficking and Immunoregulation, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore.

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http://link.springer.com/10.1007/s00018-011-0887-z
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http://dx.doi.org/10.1007/s00018-011-0887-zDOI Listing
May 2012

A novel CARD containing splice-isoform of CIITA regulates nitric oxide synthesis in dendritic cells.

Protein Cell 2010 Mar 17;1(3):291-306. Epub 2010 Apr 17.

Laboratory of Membrane Trafficking and Immunoregulation, Department of Microbiology, Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Block MD4, 5 Science Drive 2, Singapore 117597, Republic of Singapore.

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http://dx.doi.org/10.1007/s13238-010-0039-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875089PMC
March 2010

Caspases regulate VAMP-8 expression and phagocytosis in dendritic cells.

Biochem Biophys Res Commun 2009 Sep 14;387(2):371-5. Epub 2009 Jul 14.

Department of Microbiology, Laboratory of Membrane Trafficking and Immunoregulation, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Republic of Singapore.

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http://dx.doi.org/10.1016/j.bbrc.2009.07.028DOI Listing
September 2009

Vesicle-associated membrane protein-8/endobrevin negatively regulates phagocytosis of bacteria in dendritic cells.

J Immunol 2008 Mar;180(5):3148-57

Laboratory of Membrane Trafficking and Immunoregulation Research, Department of Microbiology, Immunology Program, Yong Loo Lin School of Medicine, National University of Singapore, Republic of Singapore.

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http://dx.doi.org/10.4049/jimmunol.180.5.3148DOI Listing
March 2008

Nitric-oxide synthase 2 interacts with CD74 and inhibits its cleavage by caspase during dendritic cell development.

J Biol Chem 2008 Jan 14;283(3):1713-22. Epub 2007 Nov 14.

Laboratory of Membrane Trafficking and Immunoregulation, Department of Microbiology, Yong Loo Lin School of Medicine.

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http://dx.doi.org/10.1074/jbc.M705998200DOI Listing
January 2008