Publications by authors named "Cyrille Lescop"

8 Publications

  • Page 1 of 1

Cenerimod, a novel selective S1P receptor modulator with unique signaling properties.

Authors:
Luca Piali Magdalena Birker-Robaczewska Cyrille Lescop Sylvie Froidevaux Nicole Schmitz Keith Morrison Christopher Kohl Markus Rey Rolf Studer Enrico Vezzali Patrick Hess Martine Clozel Beat Steiner Martin H Bolli Oliver Nayler

Pharmacol Res Perspect 2017 12;5(6)

Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

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December 2017

S1P Modulator-Induced G Signaling and -Arrestin Recruitment Are Both Necessary to Induce Rapid and Efficient Reduction of Blood Lymphocyte Count In Vivo.

Authors:
Magdalena Birker-Robaczewska Martin Bolli Markus Rey Ruben de Kanter Christopher Kohl Cyrille Lescop Maxime Boucher Sylvie Poirey Beat Steiner Oliver Nayler

Mol Pharmacol 2018 02 4;93(2):109-118. Epub 2017 Dec 4.

Idorsia Pharmaceuticals Ltd., Allschwil, Switzerland.

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February 2018

Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groups.

Authors:
Cyrille Lescop Claus Müller Boris Mathys Magdalena Birker Ruben de Kanter Christopher Kohl Patrick Hess Oliver Nayler Markus Rey Patrick Sieber Beat Steiner Thomas Weller Martin H Bolli

Eur J Med Chem 2016 Jun 23;116:222-238. Epub 2016 Mar 23.

Drug Discovery Chemistry, Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.

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June 2016

Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridines.

Authors:
Martin H Bolli Cyrille Lescop Magdalena Birker Ruben de Kanter Patrick Hess Christopher Kohl Oliver Nayler Markus Rey Patrick Sieber Jörg Velker Thomas Weller Beat Steiner

Eur J Med Chem 2016 Jun 12;115:326-41. Epub 2016 Mar 12.

Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.

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June 2016

Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.

Authors:
Martin H Bolli Stefan Abele Magdalena Birker Roberto Bravo Daniel Bur Ruben de Kanter Christopher Kohl Julien Grimont Patrick Hess Cyrille Lescop Boris Mathys Claus Müller Oliver Nayler Markus Rey Michael Scherz Gunther Schmidt Jürgen Seifert Beat Steiner Jörg Velker Thomas Weller

J Med Chem 2014 Jan 24;57(1):110-30. Epub 2013 Dec 24.

Drug Discovery Chemistry, Actelion Pharmaceuticals Ltd. , Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.

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January 2014

Synthetic sphingosine 1-phosphate receptor modulators--opportunities and potential pitfalls.

Authors:
Martin H Bolli Cyrille Lescop Oliver Nayler

Curr Top Med Chem 2011 ;11(6):726-57

Drug Discovery Chemistry, Actelion Pharmaceuticals Ltd., Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.

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September 2011

Effect of calpain and proteasome inhibition on Ca2+-dependent proteolysis and muscle histopathology in the mdx mouse.

Authors:
Alexandre Briguet Michael Erb Isabelle Courdier-Fruh Patrizia Barzaghi Gesa Santos Holger Herzner Cyrille Lescop Hervé Siendt Marco Henneboehle Philipp Weyermann Josef P Magyar Judith Dubach-Powell Günther Metz Thomas Meier

FASEB J 2008 Dec 26;22(12):4190-200. Epub 2008 Aug 26.

Santhera Pharmaceuticals (Switzerland) Ltd, Hammerstrasse 47, CH-4410 Liestal, Switzerland.

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December 2008

Novel cell-penetrating alpha-keto-amide calpain inhibitors as potential treatment for muscular dystrophy.

Authors:
Cyrille Lescop Holger Herzner Hervé Siendt Reto Bolliger Marco Henneböhle Philipp Weyermann Alexandre Briguet Isabelle Courdier-Fruh Michael Erb Mark Foster Thomas Meier Josef P Magyar Andreas von Sprecher

Bioorg Med Chem Lett 2005 Dec 26;15(23):5176-81. Epub 2005 Sep 26.

Medicinal Chemistry Department, Santhera Pharmaceuticals, Hammerstrasse 25, CH-4410 Liestal, Switzerland.

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December 2005