Publications by authors named "Cyriel Y Ponsioen"

100Publications

Impaired Quality of Working Life in Inflammatory Bowel Disease Patients.

Dig Dis Sci 2020 Oct 16. Epub 2020 Oct 16.

Department of Public and Occupational Health, Amsterdam UMC, Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.

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October 2020

The Simple Cholestatic Complaints Score is a valid and quick patient-reported outcome measure in primary sclerosing cholangitis.

Liver Int 2020 11;40(11):2758-2766

Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, location AMC, Amsterdam Gastroenterology & Metabolism, Amsterdam, The Netherlands.

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November 2020

Letter to the Editor: Fair Comparisons in the Arena of Risk Scores.

Hepatology 2020 01 24;71(1):398-399. Epub 2019 Dec 24.

Department of Gastroenterology & Hepatology, Amsterdam University Medical Center Location AMC, Amsterdam, the Netherlands.

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January 2020

Return to sender: Lymphocyte trafficking mechanisms as contributors to primary sclerosing cholangitis.

J Hepatol 2019 09 18;71(3):603-615. Epub 2019 May 18.

Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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September 2019

Off-label prescriptions of drugs used for the treatment of Crohn's disease or ulcerative colitis.

Aliment Pharmacol Ther 2019 05 25;49(10):1293-1300. Epub 2019 Mar 25.

Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit Amsterdam, AG&M research institute, Amsterdam, The Netherlands.

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May 2019

Relapse rates and predictors for relapse in a real-life cohort of IBD patients after discontinuation of anti-TNF therapy.

Scand J Gastroenterol 2019 Mar 23;54(3):281-288. Epub 2019 Mar 23.

a Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam , Amsterdam , The Netherlands.

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March 2019

Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis.

Clin Gastroenterol Hepatol 2019 09 4;17(10):2076-2084.e2. Epub 2019 Jan 4.

Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, Rotterdam, The Netherlands; Toronto Centre for Liver Disease, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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September 2019

Comparison of MRI Activity Scoring Systems and Features for the Terminal Ileum in Patients With Crohn Disease.

AJR Am J Roentgenol 2019 02 12;212(2):W25-W31. Epub 2018 Dec 12.

1 Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.

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February 2019

Comparison of contrast-enhanced and diffusion-weighted MRI in assessment of the terminal ileum in Crohn's disease patients.

Abdom Radiol (NY) 2019 02;44(2):398-405

Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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February 2019

Design and Endpoints for Clinical Trials in Primary Sclerosing Cholangitis.

Hepatology 2018 09 31;68(3):1174-1188. Epub 2018 Aug 31.

Division of Gastroenterology and Inborn Errors Products, United States Food and Drug Administration, Silver Spring, MD.

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September 2018

Semiautomatic Assessment of the Terminal Ileum and Colon in Patients with Crohn Disease Using MRI (the VIGOR++ Project).

Acad Radiol 2018 08 7;25(8):1038-1045. Epub 2018 Feb 7.

Department of Radiology and Nuclear Medicine, Academic Medical Centre, Meibergdreef 9, P.O 22660, 1100DD, Amsterdam, The Netherlands; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands.

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August 2018

High Risk of Advanced Colorectal Neoplasia in Patients With Primary Sclerosing Cholangitis Associated With Inflammatory Bowel Disease.

Clin Gastroenterol Hepatol 2018 07 15;16(7):1106-1113.e3. Epub 2018 Mar 15.

The Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York; Surgical Department, Gastroenterology Division, Hospital Beatriz Ângelo, Loures, Portugal. Electronic address:

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July 2018

Endpoints in the design of clinical trials for primary sclerosing cholangitis.

Biochim Biophys Acta Mol Basis Dis 2018 04 25;1864(4 Pt B):1410-1414. Epub 2017 Aug 25.

Department of Gastroenterology & Hepatology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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April 2018

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.

Gut 2018 08 4;67(8):1517-1524. Epub 2017 Aug 4.

Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.

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August 2018

Clinical Predictors of Future Nonadherence in Inflammatory Bowel Disease.

Inflamm Bowel Dis 2017 09;23(9):1568-1576

1Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands; 2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; 3Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands; 4Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; 5Department of Gastroenterology and Hepatology (Co-MIK), Zuyderland Medical Center, Heerlen, Sittard, Geleen, the Netherlands; 6Department of Gastroenterology and Hepatology, Diaconessenhuis, Leiden, the Netherlands; 7Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands; 8Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; 9Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; 10Department of Gastroenterology and Hepatology, Antonius Hospital, Nieuwegein, the Netherlands; 11Department of Gastroenterology and Hepatology, Slingeland Hospital, Doetinchem, the Netherlands; 12Department of Gastroenterology and Hepatology, Leiden University Medical Center, the Netherlands; 13Department of Gastroenterology and Hepatology, Maastricht University Medical Center, the Netherlands; 14Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands; 15Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands; and 16Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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September 2017

Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.

Gastroenterology 2017 06 6;152(8):1975-1984.e8. Epub 2017 Mar 6.

Norwegian PSC Research Center and Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address:

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June 2017

Comparison of health-related quality of life and disability in ulcerative colitis patients following restorative proctocolectomy with ileal pouch-anal anastomosis versus anti-tumor necrosis factor therapy.

Eur J Gastroenterol Hepatol 2017 Mar;29(3):338-344

Departments of aGastroenterology and Hepatology bSurgery, Academic Medical Center, Amsterdam, The Netherlands Departments of cAbdominal Surgery dGastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.

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March 2017

Low Rate of Dysplasia Detection in Mucosa Surrounding Dysplastic Lesions in Patients Undergoing Surveillance for Inflammatory Bowel Diseases.

Clin Gastroenterol Hepatol 2017 02 6;15(2):222-228.e2. Epub 2016 Sep 6.

Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

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February 2017

MRI characteristics of proctitis in Crohn's disease on perianal MRI.

Abdom Radiol (NY) 2016 10;41(10):1918-30

Department of Radiology, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands.

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October 2016

Burden of disease and increasing prevalence of inflammatory bowel disease in a population-based cohort in the Netherlands.

Eur J Gastroenterol Hepatol 2016 Sep;28(9):1065-72

Departments of aGastroenterology and Hepatology bSurgery cMedical Psychology, Academic Medical Center, Amsterdam dDepartment of Gastroenterology and Hepatology, Tergooi, Hilversum and Blaricum eDepartment of Gastroenterology and Hepatology, Flevohospital, Almere, The Netherlands.

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September 2016

Genetic Abnormalities in Biliary Brush Samples for Distinguishing Cholangiocarcinoma from Benign Strictures in Primary Sclerosing Cholangitis.

Gastroenterol Res Pract 2016 3;2016:4381513. Epub 2016 Apr 3.

Department of Gastroenterology and Hepatology, Academic Medical Center, 1100 DD Amsterdam, Netherlands; Center for Experimental and Molecular Medicine, Academic Medical Center, 1100 DD Amsterdam, Netherlands.

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April 2016

Alkaline phosphatase at diagnosis of primary sclerosing cholangitis and 1 year later: evaluation of prognostic value.

Liver Int 2016 12 4;36(12):1867-1875. Epub 2016 Apr 4.

Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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December 2016

Short article: Remicade infusions at home: an alternative setting of infliximab therapy for patients with Crohn's disease.

Eur J Gastroenterol Hepatol 2016 Feb;28(2):222-5

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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February 2016

Incidence and Severity of Prepouch Ileitis: A Distinct Disease Entity or a Manifestation of Refractory Pouchitis?

Inflamm Bowel Dis 2016 Mar;22(3):662-8

*Department of Gastroenterology, University College London Hospital, United Kingdom; †Robarts Clinical Trials Inc., Amsterdam, the Netherlands; ‡Department of Gastroenterology, Academic Medical Center, Amsterdam, the Netherlands; §Department of Surgery, Academic Medical Centre, Amsterdam, the Netherlands; and ‖Department of Surgery, University Hospitals, Leuven, Belgium.

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March 2016

Applicability and prognostic value of histologic scoring systems in primary sclerosing cholangitis.

J Hepatol 2015 Nov 18;63(5):1212-9. Epub 2015 Jun 18.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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November 2015

Incidence of Interval Colorectal Cancer Among Inflammatory Bowel Disease Patients Undergoing Regular Colonoscopic Surveillance.

Clin Gastroenterol Hepatol 2015 Sep 6;13(9):1656-61. Epub 2015 May 6.

Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

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September 2015

Fecal microbiota transplantation as novel therapy in gastroenterology: A systematic review.

World J Gastroenterol 2015 May;21(17):5359-71

Noortje G Rossen, Elisabeth M de Vries, Geert R D'Haens, Cyriel Y Ponsioen, Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam, 1105 AZ Amsterdam, The Netherlands.

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May 2015

Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis.

Gastroenterology 2015 Aug 25;149(2):350-5.e2. Epub 2015 Apr 25.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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August 2015

Biomarkers for disease progression of primary sclerosing cholangitis.

Curr Opin Gastroenterol 2015 May;31(3):239-46

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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May 2015

Self-reported disability in patients with inflammatory bowel disease largely determined by disease activity and illness perceptions.

Inflamm Bowel Dis 2015 Feb;21(2):369-77

1Department of Gastroenterology and Hepatology, University Medical Center Utrecht, the Netherlands; 2Medical Psychology Section, Leiden University Medical Center, Leiden, the Netherlands; 3Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; 4Department of Gastroenterology and Hepatology, Orbis Medical Center, Sittard, the Netherlands; 5Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands; 6University of Groningen, Groningen, the Netherlands; 7Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; 8Division of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands; 9Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands; 10Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands; 11Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands; 12Department of Gastroenterology and Hepatology, Slingeland Hospital, Doetinchem, the Netherlands; 13Department of Gastroenterology and Hepatology, Diaconessenhuis, Leiden, the Netherlands; 14Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; 15Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands; 16Department of Gastroenterology and Hepatology, Reinier de Graaf Groep, Delft, the Netherlands; and 17Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands.

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February 2015

Acute dysphagia: don't wait and see.

Gastroenterology 2014 Aug 25;147(2):281-2. Epub 2014 Jun 25.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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August 2014

Vitamin D deficiency in Crohn's disease and healthy controls: a prospective case-control study in the Netherlands.

J Crohns Colitis 2014 Oct 23;8(10):1267-73. Epub 2014 Mar 23.

Dept. of Gastroenterology and Hepatology, Academic Medical Center (AMC) Amsterdam, The Netherlands. Electronic address:

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October 2014

Effect of aging on healthcare costs of inflammatory bowel disease: a glimpse into the future.

Inflamm Bowel Dis 2014 Apr;20(4):637-45

1Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, the Netherlands 2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands; 3Agis Health Insurance, Amersfoort, the Netherlands; 4Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, the Netherlands; 5Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands; 6Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands; 7Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands; 8Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands; 9Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands; 10Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands; 11Department of Gastroenterology and Hepatology, Slingeland Hospital, Doetinchem, the Netherlands; 12Department of Gastroenterology and Hepatology, Orbis Medical Center, Sittard, the Netherlands; 13Department of Gastroenterology and Hepatology, Diaconessenhuis, Leiden, the Netherlands; 14Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands; 15Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, the Netherlands; 16Department of Gastroenterology and Hepatology, Reinier de Graaf Groep, Delft, the Netherlands; and 17Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, the Netherlands.

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April 2014

Effects of infliximab retreatment after consecutive discontinuation of infliximab and adalimumab in refractory Crohn's disease.

Inflamm Bowel Dis 2014 Feb;20(2):251-8

*Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands; †Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands; and ‡Department of Gastroenterology and Hepatology, Medisch Centrum Alkmaar, North Holland, The Netherlands.

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February 2014

Prior colorectal neoplasia is associated with increased risk of ileoanal pouch neoplasia in patients with inflammatory bowel disease.

Gastroenterology 2014 Jan 25;146(1):119-28.e1. Epub 2013 Sep 25.

Inflammatory Bowel Disease Center, Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. Electronic address:

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January 2014

Reply to Drs. Walmsley and Casey letter.

J Crohns Colitis 2013 Dec 7;7(11):932. Epub 2013 Aug 7.

Academic Medical Centre, Amsterdam, The Netherlands. Electronic address:

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December 2013